Movement Disorders (revue)

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Fulminant lewy body disease

Identifieur interne : 001941 ( PascalFrancis/Corpus ); précédent : 001940; suivant : 001942

Fulminant lewy body disease

Auteurs : Isabelle Momjian-Mayor ; Gian Paolo Pizzolato ; Karim Burkhardt ; Theodor Landis ; Alessandra Coeytaux ; Pierre R. Burkhard

Source :

RBID : Pascal:06-0538601

Descripteurs français

English descriptors

Abstract

The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 21
A06       @2 10
A08 01  1  ENG  @1 Fulminant lewy body disease
A11 01  1    @1 MOMJIAN-MAYOR (Isabelle)
A11 02  1    @1 PIZZOLATO (Gian Paolo)
A11 03  1    @1 BURKHARDT (Karim)
A11 04  1    @1 LANDIS (Theodor)
A11 05  1    @1 COEYTAUX (Alessandra)
A11 06  1    @1 BURKHARD (Pierre R.)
A14 01      @1 Department of Neurology, Geneva University Hospitals and Medical School @2 Geneva @3 CHE @Z 1 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut.
A14 02      @1 Neuropathology Unit, Department of Pathology, Geneva University Hospitals and Medical School @2 Geneva @3 CHE @Z 2 aut. @Z 3 aut.
A20       @1 1748-1751
A21       @1 2006
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000158877800310
A44       @0 0000 @1 © 2006 INIST-CNRS. All rights reserved.
A45       @0 18 ref.
A47 01  1    @0 06-0538601
A60       @1 P @3 CC
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C02 03  X    @0 002B17A03
C03 01  X  FRE  @0 Système nerveux pathologie @5 01
C03 01  X  ENG  @0 Nervous system diseases @5 01
C03 01  X  SPA  @0 Sistema nervioso patología @5 01
C03 02  X  FRE  @0 Parkinson maladie @5 02
C03 02  X  ENG  @0 Parkinson disease @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @5 02
C03 03  X  FRE  @0 Démence @5 03
C03 03  X  ENG  @0 Dementia @5 03
C03 03  X  SPA  @0 Demencia @5 03
C03 04  X  FRE  @0 Fulminant @5 09
C03 04  X  ENG  @0 Fulminant @5 09
C03 04  X  SPA  @0 Fulminante @5 09
C03 05  X  FRE  @0 Corps Lewy @5 10
C03 05  X  ENG  @0 Lewy body @5 10
C03 05  X  SPA  @0 Cuerpo Lewy @5 10
C03 06  X  FRE  @0 Corps Lewy maladie @4 CD @5 96
C03 06  X  ENG  @0 Lewy body disease @4 CD @5 96
C03 06  X  SPA  @0 Cuerpo Lewy enfermedad @4 CD @5 96
C07 01  X  FRE  @0 Encéphale pathologie @5 37
C07 01  X  ENG  @0 Cerebral disorder @5 37
C07 01  X  SPA  @0 Encéfalo patología @5 37
C07 02  X  FRE  @0 Extrapyramidal syndrome @5 38
C07 02  X  ENG  @0 Extrapyramidal syndrome @5 38
C07 02  X  SPA  @0 Extrapiramidal síndrome @5 38
C07 03  X  FRE  @0 Maladie dégénérative @5 39
C07 03  X  ENG  @0 Degenerative disease @5 39
C07 03  X  SPA  @0 Enfermedad degenerativa @5 39
C07 04  X  FRE  @0 Système nerveux central pathologie @5 40
C07 04  X  ENG  @0 Central nervous system disease @5 40
C07 04  X  SPA  @0 Sistema nervosio central patología @5 40
N21       @1 353
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 06-0538601 INIST
ET : Fulminant lewy body disease
AU : MOMJIAN-MAYOR (Isabelle); PIZZOLATO (Gian Paolo); BURKHARDT (Karim); LANDIS (Theodor); COEYTAUX (Alessandra); BURKHARD (Pierre R.)
AF : Department of Neurology, Geneva University Hospitals and Medical School/Geneva/Suisse (1 aut., 4 aut., 5 aut., 6 aut.); Neuropathology Unit, Department of Pathology, Geneva University Hospitals and Medical School/Geneva/Suisse (2 aut., 3 aut.)
DT : Publication en série; Courte communication, note brève; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 10; Pp. 1748-1751; Bibl. 18 ref.
LA : Anglais
EA : The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity.
CC : 002B17; 002B17G; 002B17A03
FD : Système nerveux pathologie; Parkinson maladie; Démence; Fulminant; Corps Lewy; Corps Lewy maladie
FG : Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie
ED : Nervous system diseases; Parkinson disease; Dementia; Fulminant; Lewy body; Lewy body disease
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD : Sistema nervioso patología; Parkinson enfermedad; Demencia; Fulminante; Cuerpo Lewy; Cuerpo Lewy enfermedad
LO : INIST-20953.354000158877800310
ID : 06-0538601

Links to Exploration step

Pascal:06-0538601

Le document en format XML

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<s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Système nerveux central pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fN21>
<s1>353</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 06-0538601 INIST</NO>
<ET>Fulminant lewy body disease</ET>
<AU>MOMJIAN-MAYOR (Isabelle); PIZZOLATO (Gian Paolo); BURKHARDT (Karim); LANDIS (Theodor); COEYTAUX (Alessandra); BURKHARD (Pierre R.)</AU>
<AF>Department of Neurology, Geneva University Hospitals and Medical School/Geneva/Suisse (1 aut., 4 aut., 5 aut., 6 aut.); Neuropathology Unit, Department of Pathology, Geneva University Hospitals and Medical School/Geneva/Suisse (2 aut., 3 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 10; Pp. 1748-1751; Bibl. 18 ref.</SO>
<LA>Anglais</LA>
<EA>The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity.</EA>
<CC>002B17; 002B17G; 002B17A03</CC>
<FD>Système nerveux pathologie; Parkinson maladie; Démence; Fulminant; Corps Lewy; Corps Lewy maladie</FD>
<FG>Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie</FG>
<ED>Nervous system diseases; Parkinson disease; Dementia; Fulminant; Lewy body; Lewy body disease</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease</EG>
<SD>Sistema nervioso patología; Parkinson enfermedad; Demencia; Fulminante; Cuerpo Lewy; Cuerpo Lewy enfermedad</SD>
<LO>INIST-20953.354000158877800310</LO>
<ID>06-0538601</ID>
</server>
</inist>
</record>

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