Fulminant lewy body disease
Identifieur interne : 001941 ( PascalFrancis/Corpus ); précédent : 001940; suivant : 001942Fulminant lewy body disease
Auteurs : Isabelle Momjian-Mayor ; Gian Paolo Pizzolato ; Karim Burkhardt ; Theodor Landis ; Alessandra Coeytaux ; Pierre R. BurkhardSource :
- Movement disorders [ 0885-3185 ] ; 2006.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
pA |
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Format Inist (serveur)
NO : | PASCAL 06-0538601 INIST |
---|---|
ET : | Fulminant lewy body disease |
AU : | MOMJIAN-MAYOR (Isabelle); PIZZOLATO (Gian Paolo); BURKHARDT (Karim); LANDIS (Theodor); COEYTAUX (Alessandra); BURKHARD (Pierre R.) |
AF : | Department of Neurology, Geneva University Hospitals and Medical School/Geneva/Suisse (1 aut., 4 aut., 5 aut., 6 aut.); Neuropathology Unit, Department of Pathology, Geneva University Hospitals and Medical School/Geneva/Suisse (2 aut., 3 aut.) |
DT : | Publication en série; Courte communication, note brève; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2006; Vol. 21; No. 10; Pp. 1748-1751; Bibl. 18 ref. |
LA : | Anglais |
EA : | The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity. |
CC : | 002B17; 002B17G; 002B17A03 |
FD : | Système nerveux pathologie; Parkinson maladie; Démence; Fulminant; Corps Lewy; Corps Lewy maladie |
FG : | Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie |
ED : | Nervous system diseases; Parkinson disease; Dementia; Fulminant; Lewy body; Lewy body disease |
EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease |
SD : | Sistema nervioso patología; Parkinson enfermedad; Demencia; Fulminante; Cuerpo Lewy; Cuerpo Lewy enfermedad |
LO : | INIST-20953.354000158877800310 |
ID : | 06-0538601 |
Links to Exploration step
Pascal:06-0538601Le document en format XML
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<EA>The clinical distinction between Parkinson's disease (PD) with dementia (PDD) and dementia with Lewy bodies (DLB) is challenged by most neuropathological studies showing nearly identical changes in both conditions. We report an unusual case of PD evolving into a rapidly progressive dementia leading to death within 3 months that showed nearly all clinical features of DLB. At autopsy, numerous Lewy bodies and Lewy neurites were found in several areas of the brainstem, the limbic system, and the neocortex, consistent with pure DLB. This case demonstrates that Lewy body disease may exhibit a dramatic course without any coexisting pathology and exemplifies that PD, PDD, and DLB may sometimes represent sequential, yet overlapping, phenotypes of a same clinicopathological entity.</EA>
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