Movement disorder society-sponsored revision of the unified Parkinson's disease rating scale (MDS-UPDRS) : Process, format, and clinimetric testing plan
Identifieur interne : 001837 ( PascalFrancis/Corpus ); précédent : 001836; suivant : 001838Movement disorder society-sponsored revision of the unified Parkinson's disease rating scale (MDS-UPDRS) : Process, format, and clinimetric testing plan
Auteurs : Christopher G. Goetz ; Stanley Fahn ; Pablo Martinez-Martin ; Werner Poewe ; Cristina Sampaio ; Glenn T. Stebbins ; Matthew B. Stern ; Barbara C. Tilley ; Richard Dodel ; Bruno Dubois ; Robert Holloway ; Joseph Jankovic ; Jaime Kulisevsky ; Anthony E. Lang ; Andrew Lees ; Sue Leurgans ; Peter A. Lewitt ; David Nyenhuis ; C. Warren Olanow ; Olivier Rascol ; Anette Schrag ; Jeanne A. Teresi ; Jacobus J. Van Hilten ; Nancy LapelleSource :
- Movement disorders [ 0885-3185 ] ; 2007.
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- Pascal (Inist)
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Abstract
This article presents the revision process, major innovations, and clinimetric testing program for the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (UPDRS), known as the MDS-UPDRS. The UPDRS is the most widely used scale for the clinical study of Parkinson's disease (PD). The MDS previously organized a critique of the UPDRS, which cited many strengths, but recommended revision of the scale to accommodate new advances and to resolve problematic areas. An MDS-UPDRS committee prepared the revision using the recommendations of the published critique of the scale. Subcommittees developed new material that was reviewed by the entire committee. A 1-day face-to-face committee meeting was organized to resolve areas of debate and to arrive at a working draft ready for clinimetric testing. The MDS-UPDRS retains the UPDRS structure of four parts with a total summed score, but the parts have been modified to provide a section that integrates nonmotor elements of PD: I, Nonmotor Experiences of Daily Living; II, Motor Experiences of Daily Living; III, Motor Examination; and IV, Motor Complications. All items have five response options with uniform anchors of 0 = normal, 1 = slight, 2 = mild, 3 = moderate, and 4 = severe. Several questions in Part I and all of Part II are written as a patient/caregiver questionnaire, so that the total rater time should remain approximately 30 minutes. Detailed instructions for testing and data acquisition accompany the MDS-UPDRS in order to increase uniform usage. Multiple language editions are planned. A three-part clinimetric program will provide testing of reliability, validity, and responsiveness to interventions. Although the MDS-UPDRS will not be published until it has successfully passed clinimetric testing, explanation of the process, key changes, and clinimetric programs allow clinicians and researchers to understand and participate in the revision process.
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NO : | PASCAL 07-0133215 INIST |
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ET : | Movement disorder society-sponsored revision of the unified Parkinson's disease rating scale (MDS-UPDRS) : Process, format, and clinimetric testing plan |
AU : | GOETZ (Christopher G.); FAHN (Stanley); MARTINEZ-MARTIN (Pablo); POEWE (Werner); SAMPAIO (Cristina); STEBBINS (Glenn T.); STERN (Matthew B.); TILLEY (Barbara C.); DODEL (Richard); DUBOIS (Bruno); HOLLOWAY (Robert); JANKOVIC (Joseph); KULISEVSKY (Jaime); LANG (Anthony E.); LEES (Andrew); LEURGANS (Sue); LEWITT (Peter A.); NYENHUIS (David); OLANOW (C. Warren); RASCOL (Olivier); SCHRAG (Anette); TERESI (Jeanne A.); VAN HILTEN (Jacobus J.); LAPELLE (Nancy) |
AF : | Department of Neurological Sciences, Rush University Medical Center/Chicago, Illinois/Etats-Unis (1 aut., 6 aut., 16 aut.); Department of Neurology, Columbia University/New York, New York/Etats-Unis (2 aut.); Department of Neuroepidemiology, Carlos III Institute/Madrid/Espagne (3 aut.); Department of Neurology, Innsbruck Medical University/Innsbruck/Autriche (4 aut.); Department of Pharmacology, Faculdade de Medicina de Lisboa/Lisboa/Portugal (5 aut.); Department of Neurology, University of Pennsylvania/Philadelphia, Pennsylvania/Etats-Unis (7 aut.); Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina/Charleston, South Carolina/Etats-Unis (8 aut.); Department of Neurology, Friedrich-Wilhelms University/Bonn/Allemagne (9 aut.); Department of Neurology, Hôpital de la Salpetriere/Paris/France (10 aut.); Department of Neurology, University of Rochester/Rochester, New York/Etats-Unis (11 aut.); Department of Neurology, Baylor College of Medicine/Houston, Texas/Etats-Unis (12 aut.); Department of Neurology, Sant Pau Hospital/Barcelona/Espagne (13 aut.); Division of Applied and Interventional Research, University of Toronto/Toronto/Canada (14 aut.); Reta Lila Weston Institute of Neurological Studies, University College/London, England/Royaume-Uni (15 aut.); Department of Neurology, Wayne State University/Detroit, Michigan/Etats-Unis (17 aut.); Department of Neurology and Rehabilitation, University of Illinois/Chicago, Illinois/Etats-Unis (18 aut.); Department of Neurology, Mount Sinai School of Medicine/New York, New York/Etats-Unis (19 aut.); Laboratoire de Pharmacologie Medicale et Clinique, Toulouse University/Toulouse/France (20 aut.); Department of Clinical Neurosciences, University College/London, England/Royaume-Uni (21 aut.); Division of General Medicine, Columbia University/New York, New York/Etats-Unis (22 aut.); Department of Neurology, Leiden University/Leiden/Pays-Bas (23 aut.); Division of Preventive and Behavioral Medicine, University of Massachusetts/Worcester, Massachusetts/Etats-Unis (24 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 1; Pp. 41-47; Bibl. 6 ref. |
LA : | Anglais |
EA : | This article presents the revision process, major innovations, and clinimetric testing program for the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (UPDRS), known as the MDS-UPDRS. The UPDRS is the most widely used scale for the clinical study of Parkinson's disease (PD). The MDS previously organized a critique of the UPDRS, which cited many strengths, but recommended revision of the scale to accommodate new advances and to resolve problematic areas. An MDS-UPDRS committee prepared the revision using the recommendations of the published critique of the scale. Subcommittees developed new material that was reviewed by the entire committee. A 1-day face-to-face committee meeting was organized to resolve areas of debate and to arrive at a working draft ready for clinimetric testing. The MDS-UPDRS retains the UPDRS structure of four parts with a total summed score, but the parts have been modified to provide a section that integrates nonmotor elements of PD: I, Nonmotor Experiences of Daily Living; II, Motor Experiences of Daily Living; III, Motor Examination; and IV, Motor Complications. All items have five response options with uniform anchors of 0 = normal, 1 = slight, 2 = mild, 3 = moderate, and 4 = severe. Several questions in Part I and all of Part II are written as a patient/caregiver questionnaire, so that the total rater time should remain approximately 30 minutes. Detailed instructions for testing and data acquisition accompany the MDS-UPDRS in order to increase uniform usage. Multiple language editions are planned. A three-part clinimetric program will provide testing of reliability, validity, and responsiveness to interventions. Although the MDS-UPDRS will not be published until it has successfully passed clinimetric testing, explanation of the process, key changes, and clinimetric programs allow clinicians and researchers to understand and participate in the revision process. |
CC : | 002B17; 002B17G; 002B17A01; 002B17A03 |
FD : | Système nerveux pathologie; Parkinson maladie; Myélodysplasique syndrome; Révision; Echelle d'évaluation |
FG : | Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Hémopathie maligne |
ED : | Nervous system diseases; Parkinson disease; Myelodysplastic syndrome; Revision; Evaluation scale |
EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Malignant hemopathy |
SD : | Sistema nervioso patología; Parkinson enfermedad; Mielodisplastico síndrome; Revisión; Escala evaluación |
LO : | INIST-20953.354000145483830060 |
ID : | 07-0133215 |
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Pascal:07-0133215Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Movement disorder society-sponsored revision of the unified Parkinson's disease rating scale (MDS-UPDRS) : Process, format, and clinimetric testing plan</title>
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<author><name sortKey="Martinez Martin, Pablo" sort="Martinez Martin, Pablo" uniqKey="Martinez Martin P" first="Pablo" last="Martinez-Martin">Pablo Martinez-Martin</name>
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<author><name sortKey="Sampaio, Cristina" sort="Sampaio, Cristina" uniqKey="Sampaio C" first="Cristina" last="Sampaio">Cristina Sampaio</name>
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<author><name sortKey="Stern, Matthew B" sort="Stern, Matthew B" uniqKey="Stern M" first="Matthew B." last="Stern">Matthew B. Stern</name>
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<author><name sortKey="Tilley, Barbara C" sort="Tilley, Barbara C" uniqKey="Tilley B" first="Barbara C." last="Tilley">Barbara C. Tilley</name>
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<author><name sortKey="Dodel, Richard" sort="Dodel, Richard" uniqKey="Dodel R" first="Richard" last="Dodel">Richard Dodel</name>
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<author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name>
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<author><name sortKey="Jankovic, Joseph" sort="Jankovic, Joseph" uniqKey="Jankovic J" first="Joseph" last="Jankovic">Joseph Jankovic</name>
<affiliation><inist:fA14 i1="11"><s1>Department of Neurology, Baylor College of Medicine</s1>
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<author><name sortKey="Kulisevsky, Jaime" sort="Kulisevsky, Jaime" uniqKey="Kulisevsky J" first="Jaime" last="Kulisevsky">Jaime Kulisevsky</name>
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<author><name sortKey="Lang, Anthony E" sort="Lang, Anthony E" uniqKey="Lang A" first="Anthony E." last="Lang">Anthony E. Lang</name>
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<author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name>
<affiliation><inist:fA14 i1="14"><s1>Reta Lila Weston Institute of Neurological Studies, University College</s1>
<s2>London, England</s2>
<s3>GBR</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
</affiliation>
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<author><name sortKey="Leurgans, Sue" sort="Leurgans, Sue" uniqKey="Leurgans S" first="Sue" last="Leurgans">Sue Leurgans</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurological Sciences, Rush University Medical Center</s1>
<s2>Chicago, Illinois</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>16 aut.</sZ>
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<author><name sortKey="Lewitt, Peter A" sort="Lewitt, Peter A" uniqKey="Lewitt P" first="Peter A." last="Lewitt">Peter A. Lewitt</name>
<affiliation><inist:fA14 i1="15"><s1>Department of Neurology, Wayne State University</s1>
<s2>Detroit, Michigan</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Nyenhuis, David" sort="Nyenhuis, David" uniqKey="Nyenhuis D" first="David" last="Nyenhuis">David Nyenhuis</name>
<affiliation><inist:fA14 i1="16"><s1>Department of Neurology and Rehabilitation, University of Illinois</s1>
<s2>Chicago, Illinois</s2>
<s3>USA</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Olanow, C Warren" sort="Olanow, C Warren" uniqKey="Olanow C" first="C. Warren" last="Olanow">C. Warren Olanow</name>
<affiliation><inist:fA14 i1="17"><s1>Department of Neurology, Mount Sinai School of Medicine</s1>
<s2>New York, New York</s2>
<s3>USA</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
</affiliation>
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<author><name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<affiliation><inist:fA14 i1="18"><s1>Laboratoire de Pharmacologie Medicale et Clinique, Toulouse University</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Schrag, Anette" sort="Schrag, Anette" uniqKey="Schrag A" first="Anette" last="Schrag">Anette Schrag</name>
<affiliation><inist:fA14 i1="19"><s1>Department of Clinical Neurosciences, University College</s1>
<s2>London, England</s2>
<s3>GBR</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Teresi, Jeanne A" sort="Teresi, Jeanne A" uniqKey="Teresi J" first="Jeanne A." last="Teresi">Jeanne A. Teresi</name>
<affiliation><inist:fA14 i1="20"><s1>Division of General Medicine, Columbia University</s1>
<s2>New York, New York</s2>
<s3>USA</s3>
<sZ>22 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Van Hilten, Jacobus J" sort="Van Hilten, Jacobus J" uniqKey="Van Hilten J" first="Jacobus J." last="Van Hilten">Jacobus J. Van Hilten</name>
<affiliation><inist:fA14 i1="21"><s1>Department of Neurology, Leiden University</s1>
<s2>Leiden</s2>
<s3>NLD</s3>
<sZ>23 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Lapelle, Nancy" sort="Lapelle, Nancy" uniqKey="Lapelle N" first="Nancy" last="Lapelle">Nancy Lapelle</name>
<affiliation><inist:fA14 i1="22"><s1>Division of Preventive and Behavioral Medicine, University of Massachusetts</s1>
<s2>Worcester, Massachusetts</s2>
<s3>USA</s3>
<sZ>24 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2007">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Evaluation scale</term>
<term>Myelodysplastic syndrome</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Revision</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Parkinson maladie</term>
<term>Myélodysplasique syndrome</term>
<term>Révision</term>
<term>Echelle d'évaluation</term>
</keywords>
</textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en">This article presents the revision process, major innovations, and clinimetric testing program for the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (UPDRS), known as the MDS-UPDRS. The UPDRS is the most widely used scale for the clinical study of Parkinson's disease (PD). The MDS previously organized a critique of the UPDRS, which cited many strengths, but recommended revision of the scale to accommodate new advances and to resolve problematic areas. An MDS-UPDRS committee prepared the revision using the recommendations of the published critique of the scale. Subcommittees developed new material that was reviewed by the entire committee. A 1-day face-to-face committee meeting was organized to resolve areas of debate and to arrive at a working draft ready for clinimetric testing. The MDS-UPDRS retains the UPDRS structure of four parts with a total summed score, but the parts have been modified to provide a section that integrates nonmotor elements of PD: I, Nonmotor Experiences of Daily Living; II, Motor Experiences of Daily Living; III, Motor Examination; and IV, Motor Complications. All items have five response options with uniform anchors of 0 = normal, 1 = slight, 2 = mild, 3 = moderate, and 4 = severe. Several questions in Part I and all of Part II are written as a patient/caregiver questionnaire, so that the total rater time should remain approximately 30 minutes. Detailed instructions for testing and data acquisition accompany the MDS-UPDRS in order to increase uniform usage. Multiple language editions are planned. A three-part clinimetric program will provide testing of reliability, validity, and responsiveness to interventions. Although the MDS-UPDRS will not be published until it has successfully passed clinimetric testing, explanation of the process, key changes, and clinimetric programs allow clinicians and researchers to understand and participate in the revision process.</div>
</front>
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<fA08 i1="01" i2="1" l="ENG"><s1>Movement disorder society-sponsored revision of the unified Parkinson's disease rating scale (MDS-UPDRS) : Process, format, and clinimetric testing plan</s1>
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<fA11 i1="01" i2="1"><s1>GOETZ (Christopher G.)</s1>
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<fA11 i1="02" i2="1"><s1>FAHN (Stanley)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>MARTINEZ-MARTIN (Pablo)</s1>
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<fA11 i1="04" i2="1"><s1>POEWE (Werner)</s1>
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<fA11 i1="05" i2="1"><s1>SAMPAIO (Cristina)</s1>
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<fA11 i1="06" i2="1"><s1>STEBBINS (Glenn T.)</s1>
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<fA11 i1="07" i2="1"><s1>STERN (Matthew B.)</s1>
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<fA11 i1="08" i2="1"><s1>TILLEY (Barbara C.)</s1>
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<fA11 i1="10" i2="1"><s1>DUBOIS (Bruno)</s1>
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<fA11 i1="11" i2="1"><s1>HOLLOWAY (Robert)</s1>
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<fA11 i1="12" i2="1"><s1>JANKOVIC (Joseph)</s1>
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<fA11 i1="13" i2="1"><s1>KULISEVSKY (Jaime)</s1>
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<fA11 i1="14" i2="1"><s1>LANG (Anthony E.)</s1>
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<fA11 i1="17" i2="1"><s1>LEWITT (Peter A.)</s1>
</fA11>
<fA11 i1="18" i2="1"><s1>NYENHUIS (David)</s1>
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<fA11 i1="19" i2="1"><s1>OLANOW (C. Warren)</s1>
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<fA11 i1="20" i2="1"><s1>RASCOL (Olivier)</s1>
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<fA11 i1="21" i2="1"><s1>SCHRAG (Anette)</s1>
</fA11>
<fA11 i1="22" i2="1"><s1>TERESI (Jeanne A.)</s1>
</fA11>
<fA11 i1="23" i2="1"><s1>VAN HILTEN (Jacobus J.)</s1>
</fA11>
<fA11 i1="24" i2="1"><s1>LAPELLE (Nancy)</s1>
</fA11>
<fA14 i1="01"><s1>Department of Neurological Sciences, Rush University Medical Center</s1>
<s2>Chicago, Illinois</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>16 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Department of Neurology, Columbia University</s1>
<s2>New York, New York</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Department of Neuroepidemiology, Carlos III Institute</s1>
<s2>Madrid</s2>
<s3>ESP</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Department of Neurology, Innsbruck Medical University</s1>
<s2>Innsbruck</s2>
<s3>AUT</s3>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Department of Pharmacology, Faculdade de Medicina de Lisboa</s1>
<s2>Lisboa</s2>
<s3>PRT</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Department of Neurology, University of Pennsylvania</s1>
<s2>Philadelphia, Pennsylvania</s2>
<s3>USA</s3>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="07"><s1>Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina</s1>
<s2>Charleston, South Carolina</s2>
<s3>USA</s3>
<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="08"><s1>Department of Neurology, Friedrich-Wilhelms University</s1>
<s2>Bonn</s2>
<s3>DEU</s3>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="09"><s1>Department of Neurology, Hôpital de la Salpetriere</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>10 aut.</sZ>
</fA14>
<fA14 i1="10"><s1>Department of Neurology, University of Rochester</s1>
<s2>Rochester, New York</s2>
<s3>USA</s3>
<sZ>11 aut.</sZ>
</fA14>
<fA14 i1="11"><s1>Department of Neurology, Baylor College of Medicine</s1>
<s2>Houston, Texas</s2>
<s3>USA</s3>
<sZ>12 aut.</sZ>
</fA14>
<fA14 i1="12"><s1>Department of Neurology, Sant Pau Hospital</s1>
<s2>Barcelona</s2>
<s3>ESP</s3>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="13"><s1>Division of Applied and Interventional Research, University of Toronto</s1>
<s2>Toronto</s2>
<s3>CAN</s3>
<sZ>14 aut.</sZ>
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<fA14 i1="14"><s1>Reta Lila Weston Institute of Neurological Studies, University College</s1>
<s2>London, England</s2>
<s3>GBR</s3>
<sZ>15 aut.</sZ>
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<fA14 i1="15"><s1>Department of Neurology, Wayne State University</s1>
<s2>Detroit, Michigan</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
</fA14>
<fA14 i1="16"><s1>Department of Neurology and Rehabilitation, University of Illinois</s1>
<s2>Chicago, Illinois</s2>
<s3>USA</s3>
<sZ>18 aut.</sZ>
</fA14>
<fA14 i1="17"><s1>Department of Neurology, Mount Sinai School of Medicine</s1>
<s2>New York, New York</s2>
<s3>USA</s3>
<sZ>19 aut.</sZ>
</fA14>
<fA14 i1="18"><s1>Laboratoire de Pharmacologie Medicale et Clinique, Toulouse University</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>20 aut.</sZ>
</fA14>
<fA14 i1="19"><s1>Department of Clinical Neurosciences, University College</s1>
<s2>London, England</s2>
<s3>GBR</s3>
<sZ>21 aut.</sZ>
</fA14>
<fA14 i1="20"><s1>Division of General Medicine, Columbia University</s1>
<s2>New York, New York</s2>
<s3>USA</s3>
<sZ>22 aut.</sZ>
</fA14>
<fA14 i1="21"><s1>Department of Neurology, Leiden University</s1>
<s2>Leiden</s2>
<s3>NLD</s3>
<sZ>23 aut.</sZ>
</fA14>
<fA14 i1="22"><s1>Division of Preventive and Behavioral Medicine, University of Massachusetts</s1>
<s2>Worcester, Massachusetts</s2>
<s3>USA</s3>
<sZ>24 aut.</sZ>
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<fC01 i1="01" l="ENG"><s0>This article presents the revision process, major innovations, and clinimetric testing program for the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (UPDRS), known as the MDS-UPDRS. The UPDRS is the most widely used scale for the clinical study of Parkinson's disease (PD). The MDS previously organized a critique of the UPDRS, which cited many strengths, but recommended revision of the scale to accommodate new advances and to resolve problematic areas. An MDS-UPDRS committee prepared the revision using the recommendations of the published critique of the scale. Subcommittees developed new material that was reviewed by the entire committee. A 1-day face-to-face committee meeting was organized to resolve areas of debate and to arrive at a working draft ready for clinimetric testing. The MDS-UPDRS retains the UPDRS structure of four parts with a total summed score, but the parts have been modified to provide a section that integrates nonmotor elements of PD: I, Nonmotor Experiences of Daily Living; II, Motor Experiences of Daily Living; III, Motor Examination; and IV, Motor Complications. All items have five response options with uniform anchors of 0 = normal, 1 = slight, 2 = mild, 3 = moderate, and 4 = severe. Several questions in Part I and all of Part II are written as a patient/caregiver questionnaire, so that the total rater time should remain approximately 30 minutes. Detailed instructions for testing and data acquisition accompany the MDS-UPDRS in order to increase uniform usage. Multiple language editions are planned. A three-part clinimetric program will provide testing of reliability, validity, and responsiveness to interventions. Although the MDS-UPDRS will not be published until it has successfully passed clinimetric testing, explanation of the process, key changes, and clinimetric programs allow clinicians and researchers to understand and participate in the revision process.</s0>
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<s5>03</s5>
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<server><NO>PASCAL 07-0133215 INIST</NO>
<ET>Movement disorder society-sponsored revision of the unified Parkinson's disease rating scale (MDS-UPDRS) : Process, format, and clinimetric testing plan</ET>
<AU>GOETZ (Christopher G.); FAHN (Stanley); MARTINEZ-MARTIN (Pablo); POEWE (Werner); SAMPAIO (Cristina); STEBBINS (Glenn T.); STERN (Matthew B.); TILLEY (Barbara C.); DODEL (Richard); DUBOIS (Bruno); HOLLOWAY (Robert); JANKOVIC (Joseph); KULISEVSKY (Jaime); LANG (Anthony E.); LEES (Andrew); LEURGANS (Sue); LEWITT (Peter A.); NYENHUIS (David); OLANOW (C. Warren); RASCOL (Olivier); SCHRAG (Anette); TERESI (Jeanne A.); VAN HILTEN (Jacobus J.); LAPELLE (Nancy)</AU>
<AF>Department of Neurological Sciences, Rush University Medical Center/Chicago, Illinois/Etats-Unis (1 aut., 6 aut., 16 aut.); Department of Neurology, Columbia University/New York, New York/Etats-Unis (2 aut.); Department of Neuroepidemiology, Carlos III Institute/Madrid/Espagne (3 aut.); Department of Neurology, Innsbruck Medical University/Innsbruck/Autriche (4 aut.); Department of Pharmacology, Faculdade de Medicina de Lisboa/Lisboa/Portugal (5 aut.); Department of Neurology, University of Pennsylvania/Philadelphia, Pennsylvania/Etats-Unis (7 aut.); Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina/Charleston, South Carolina/Etats-Unis (8 aut.); Department of Neurology, Friedrich-Wilhelms University/Bonn/Allemagne (9 aut.); Department of Neurology, Hôpital de la Salpetriere/Paris/France (10 aut.); Department of Neurology, University of Rochester/Rochester, New York/Etats-Unis (11 aut.); Department of Neurology, Baylor College of Medicine/Houston, Texas/Etats-Unis (12 aut.); Department of Neurology, Sant Pau Hospital/Barcelona/Espagne (13 aut.); Division of Applied and Interventional Research, University of Toronto/Toronto/Canada (14 aut.); Reta Lila Weston Institute of Neurological Studies, University College/London, England/Royaume-Uni (15 aut.); Department of Neurology, Wayne State University/Detroit, Michigan/Etats-Unis (17 aut.); Department of Neurology and Rehabilitation, University of Illinois/Chicago, Illinois/Etats-Unis (18 aut.); Department of Neurology, Mount Sinai School of Medicine/New York, New York/Etats-Unis (19 aut.); Laboratoire de Pharmacologie Medicale et Clinique, Toulouse University/Toulouse/France (20 aut.); Department of Clinical Neurosciences, University College/London, England/Royaume-Uni (21 aut.); Division of General Medicine, Columbia University/New York, New York/Etats-Unis (22 aut.); Department of Neurology, Leiden University/Leiden/Pays-Bas (23 aut.); Division of Preventive and Behavioral Medicine, University of Massachusetts/Worcester, Massachusetts/Etats-Unis (24 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 1; Pp. 41-47; Bibl. 6 ref.</SO>
<LA>Anglais</LA>
<EA>This article presents the revision process, major innovations, and clinimetric testing program for the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (UPDRS), known as the MDS-UPDRS. The UPDRS is the most widely used scale for the clinical study of Parkinson's disease (PD). The MDS previously organized a critique of the UPDRS, which cited many strengths, but recommended revision of the scale to accommodate new advances and to resolve problematic areas. An MDS-UPDRS committee prepared the revision using the recommendations of the published critique of the scale. Subcommittees developed new material that was reviewed by the entire committee. A 1-day face-to-face committee meeting was organized to resolve areas of debate and to arrive at a working draft ready for clinimetric testing. The MDS-UPDRS retains the UPDRS structure of four parts with a total summed score, but the parts have been modified to provide a section that integrates nonmotor elements of PD: I, Nonmotor Experiences of Daily Living; II, Motor Experiences of Daily Living; III, Motor Examination; and IV, Motor Complications. All items have five response options with uniform anchors of 0 = normal, 1 = slight, 2 = mild, 3 = moderate, and 4 = severe. Several questions in Part I and all of Part II are written as a patient/caregiver questionnaire, so that the total rater time should remain approximately 30 minutes. Detailed instructions for testing and data acquisition accompany the MDS-UPDRS in order to increase uniform usage. Multiple language editions are planned. A three-part clinimetric program will provide testing of reliability, validity, and responsiveness to interventions. Although the MDS-UPDRS will not be published until it has successfully passed clinimetric testing, explanation of the process, key changes, and clinimetric programs allow clinicians and researchers to understand and participate in the revision process.</EA>
<CC>002B17; 002B17G; 002B17A01; 002B17A03</CC>
<FD>Système nerveux pathologie; Parkinson maladie; Myélodysplasique syndrome; Révision; Echelle d'évaluation</FD>
<FG>Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Hémopathie maligne</FG>
<ED>Nervous system diseases; Parkinson disease; Myelodysplastic syndrome; Revision; Evaluation scale</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Malignant hemopathy</EG>
<SD>Sistema nervioso patología; Parkinson enfermedad; Mielodisplastico síndrome; Revisión; Escala evaluación</SD>
<LO>INIST-20953.354000145483830060</LO>
<ID>07-0133215</ID>
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