Movement Disorders (revue)

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Pathological gambling in parkinson's disease : Risk factors and differences from dopamine dysregulation. An analysis of published case series

Identifieur interne : 001539 ( PascalFrancis/Corpus ); précédent : 001538; suivant : 001540

Pathological gambling in parkinson's disease : Risk factors and differences from dopamine dysregulation. An analysis of published case series

Auteurs : David A. Gallagher ; Sean S. O'Sullivan ; Andrew H. Evans ; Andrew J. Lees ; Anette Schrag

Source :

RBID : Pascal:07-0491123

Descripteurs français

English descriptors

Abstract

Pathological gambling (PG) has been reported as a complication of the treatment of Parkinson's disease (PD). We examined all published cases of PG for prevalence and risk factors of this complication, the relationship of PG and use of dopamine agonists (DA), and the relationship of PG to the dopamine dysregulation syndrome (DDS). The prevalence of PG in prospective studies of PD patients using DA has been reported between 2.3 and 8%, compared to approximately 1% in the general population. As in the general population, PD patients with this complication are often young, male and have psychiatric co-morbidity. The vast majority are on DA, often at maximum dose or above. Differences between oral DA failed to reach significance. PG associated with levodopa monotherapy is uncommon, but in the majority of cases levodopa is co-prescribed, suggesting possible cross-sensitization of brain systems mediating reward. PG can occur with DDS but often occurs in isolation. In contrast to DDS, escalation and self regulation of anti-parkinsonian medication are not usually seen. PG in patients with PD using DA is higher than PG reported in the general population, but shares similar characteristics and risk factors. PG is predominantly associated with oral DA. It often occurs in isolation and may not be associated with DDS, which typically occurs on treatment with levodopa or subcutaneous apomorphine.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A08 01  1  ENG  @1 Pathological gambling in parkinson's disease : Risk factors and differences from dopamine dysregulation. An analysis of published case series
A11 01  1    @1 GALLAGHER (David A.)
A11 02  1    @1 O'SULLIVAN (Sean S.)
A11 03  1    @1 EVANS (Andrew H.)
A11 04  1    @1 LEES (Andrew J.)
A11 05  1    @1 SCHRAG (Anette)
A14 01      @1 Department of Clinical Neurosciences, Royal Free & University College Medical School @2 London @3 GBR @Z 1 aut. @Z 5 aut.
A14 02      @1 Institute of Neurology, University College London @2 London @3 GBR @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
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A44       @0 0000 @1 © 2007 INIST-CNRS. All rights reserved.
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A47 01  1    @0 07-0491123
A60       @1 P
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C01 01    ENG  @0 Pathological gambling (PG) has been reported as a complication of the treatment of Parkinson's disease (PD). We examined all published cases of PG for prevalence and risk factors of this complication, the relationship of PG and use of dopamine agonists (DA), and the relationship of PG to the dopamine dysregulation syndrome (DDS). The prevalence of PG in prospective studies of PD patients using DA has been reported between 2.3 and 8%, compared to approximately 1% in the general population. As in the general population, PD patients with this complication are often young, male and have psychiatric co-morbidity. The vast majority are on DA, often at maximum dose or above. Differences between oral DA failed to reach significance. PG associated with levodopa monotherapy is uncommon, but in the majority of cases levodopa is co-prescribed, suggesting possible cross-sensitization of brain systems mediating reward. PG can occur with DDS but often occurs in isolation. In contrast to DDS, escalation and self regulation of anti-parkinsonian medication are not usually seen. PG in patients with PD using DA is higher than PG reported in the general population, but shares similar characteristics and risk factors. PG is predominantly associated with oral DA. It often occurs in isolation and may not be associated with DDS, which typically occurs on treatment with levodopa or subcutaneous apomorphine.
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Format Inist (serveur)

NO : PASCAL 07-0491123 INIST
ET : Pathological gambling in parkinson's disease : Risk factors and differences from dopamine dysregulation. An analysis of published case series
AU : GALLAGHER (David A.); O'SULLIVAN (Sean S.); EVANS (Andrew H.); LEES (Andrew J.); SCHRAG (Anette)
AF : Department of Clinical Neurosciences, Royal Free & University College Medical School/London/Royaume-Uni (1 aut., 5 aut.); Institute of Neurology, University College London/London/Royaume-Uni (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 12; Pp. 1757-1763; Bibl. 50 ref.
LA : Anglais
EA : Pathological gambling (PG) has been reported as a complication of the treatment of Parkinson's disease (PD). We examined all published cases of PG for prevalence and risk factors of this complication, the relationship of PG and use of dopamine agonists (DA), and the relationship of PG to the dopamine dysregulation syndrome (DDS). The prevalence of PG in prospective studies of PD patients using DA has been reported between 2.3 and 8%, compared to approximately 1% in the general population. As in the general population, PD patients with this complication are often young, male and have psychiatric co-morbidity. The vast majority are on DA, often at maximum dose or above. Differences between oral DA failed to reach significance. PG associated with levodopa monotherapy is uncommon, but in the majority of cases levodopa is co-prescribed, suggesting possible cross-sensitization of brain systems mediating reward. PG can occur with DDS but often occurs in isolation. In contrast to DDS, escalation and self regulation of anti-parkinsonian medication are not usually seen. PG in patients with PD using DA is higher than PG reported in the general population, but shares similar characteristics and risk factors. PG is predominantly associated with oral DA. It often occurs in isolation and may not be associated with DDS, which typically occurs on treatment with levodopa or subcutaneous apomorphine.
CC : 002B17; 002B17G; 002B17E
FD : Système nerveux pathologie; Jeu pathologique; Parkinson maladie; Trouble contrôle impulsion; Facteur risque; Dopamine
FG : Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Catécholamine; Neurotransmetteur
ED : Nervous system diseases; Pathological gambling; Parkinson disease; Impulse control disorder; Risk factor; Dopamine
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Catecholamine; Neurotransmitter
SD : Sistema nervioso patología; Juego patológico; Parkinson enfermedad; Trastorno control impulso; Factor riesgo; Dopamina
LO : INIST-20953.354000143464810100
ID : 07-0491123

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Pascal:07-0491123

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</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Parkinson disease</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Parkinson enfermedad</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Trouble contrôle impulsion</s0>
<s2>NM</s2>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Impulse control disorder</s0>
<s2>NM</s2>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Trastorno control impulso</s0>
<s2>NM</s2>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Facteur risque</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Risk factor</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Factor riesgo</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Dopamine</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Dopamine</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Dopamina</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>10</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Encéphale pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Système nerveux central pathologie</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Catécholamine</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Catecholamine</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Catecolamina</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Neurotransmetteur</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Neurotransmitter</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Neurotransmisor</s0>
<s5>42</s5>
</fC07>
<fN21>
<s1>323</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 07-0491123 INIST</NO>
<ET>Pathological gambling in parkinson's disease : Risk factors and differences from dopamine dysregulation. An analysis of published case series</ET>
<AU>GALLAGHER (David A.); O'SULLIVAN (Sean S.); EVANS (Andrew H.); LEES (Andrew J.); SCHRAG (Anette)</AU>
<AF>Department of Clinical Neurosciences, Royal Free & University College Medical School/London/Royaume-Uni (1 aut., 5 aut.); Institute of Neurology, University College London/London/Royaume-Uni (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 12; Pp. 1757-1763; Bibl. 50 ref.</SO>
<LA>Anglais</LA>
<EA>Pathological gambling (PG) has been reported as a complication of the treatment of Parkinson's disease (PD). We examined all published cases of PG for prevalence and risk factors of this complication, the relationship of PG and use of dopamine agonists (DA), and the relationship of PG to the dopamine dysregulation syndrome (DDS). The prevalence of PG in prospective studies of PD patients using DA has been reported between 2.3 and 8%, compared to approximately 1% in the general population. As in the general population, PD patients with this complication are often young, male and have psychiatric co-morbidity. The vast majority are on DA, often at maximum dose or above. Differences between oral DA failed to reach significance. PG associated with levodopa monotherapy is uncommon, but in the majority of cases levodopa is co-prescribed, suggesting possible cross-sensitization of brain systems mediating reward. PG can occur with DDS but often occurs in isolation. In contrast to DDS, escalation and self regulation of anti-parkinsonian medication are not usually seen. PG in patients with PD using DA is higher than PG reported in the general population, but shares similar characteristics and risk factors. PG is predominantly associated with oral DA. It often occurs in isolation and may not be associated with DDS, which typically occurs on treatment with levodopa or subcutaneous apomorphine.</EA>
<CC>002B17; 002B17G; 002B17E</CC>
<FD>Système nerveux pathologie; Jeu pathologique; Parkinson maladie; Trouble contrôle impulsion; Facteur risque; Dopamine</FD>
<FG>Encéphale pathologie; Extrapyramidal syndrome; Maladie dégénérative; Système nerveux central pathologie; Catécholamine; Neurotransmetteur</FG>
<ED>Nervous system diseases; Pathological gambling; Parkinson disease; Impulse control disorder; Risk factor; Dopamine</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Catecholamine; Neurotransmitter</EG>
<SD>Sistema nervioso patología; Juego patológico; Parkinson enfermedad; Trastorno control impulso; Factor riesgo; Dopamina</SD>
<LO>INIST-20953.354000143464810100</LO>
<ID>07-0491123</ID>
</server>
</inist>
</record>

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