Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait
Identifieur interne : 001457 ( PascalFrancis/Corpus ); précédent : 001456; suivant : 001458Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait
Auteurs : Orna Moore ; Chava Peretz ; Nir GiladiSource :
- Movement disorders [ 0885-3185 ] ; 2007.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
The aim of this study was to examine the association between freezing of gait (FOG) and quality of life (QoL) in patients with Parkinson's disease (PD). PD patients (n = 118) completed the PDQ-39 (QoL) and FOG-Q questionnaires. Disease severity was assessed by the Hoehn and Yahr (H&Y) staging and the Unified Parkinson's Disease Rating Scale (UPDRS). The relations between those parameters were assessed using regression models. 66 men and 52 women (mean age 65.8 ± 10.2 years, UPDRS total score 48.4 ± 17.1, disease duration 8.5 ± 5.8 years, H&Y stage 2.7 ± 0.8) participated. FOG severity had a significant effect on QoL (P < 0.0015), accounting for disease severity assessed by UPDRS. Specifically, FOG severity was correlated with all the dimensions of the PDQ-39 except for stigma and social support, as follows: with mobility, bodily discomfort, activity of daily living (ADL) (P < 0.005 in all), with emotional, communication, and cognition (P < 0.05 in all). FOG severity (FOG-Q) was also found to affect a modified PDQ total score, without the mobility aspect (P = 0.0081). FOG should be viewed as a highly important symptom with regard to QoL of PD patients beyond its effect on gait and mobility. On the basis of the present results, special attention should be given to FOG in the treatment of patients with PD.
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Format Inist (serveur)
NO : | PASCAL 08-0071404 INIST |
---|---|
ET : | Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait |
AU : | MOORE (Orna); PERETZ (Chava); GILADI (Nir) |
AF : | Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center/Tel Aviv/Israël (1 aut., 2 aut., 3 aut.); School of Health Professions, Tel-Aviv University/Tel-Aviv/Israël (2 aut., 3 aut.); Sackler Faculty of Medicine, Tel-Aviv University/Tel-Aviv/Israël (3 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 15; Pp. 2192-2195; Bibl. 28 ref. |
LA : | Anglais |
EA : | The aim of this study was to examine the association between freezing of gait (FOG) and quality of life (QoL) in patients with Parkinson's disease (PD). PD patients (n = 118) completed the PDQ-39 (QoL) and FOG-Q questionnaires. Disease severity was assessed by the Hoehn and Yahr (H&Y) staging and the Unified Parkinson's Disease Rating Scale (UPDRS). The relations between those parameters were assessed using regression models. 66 men and 52 women (mean age 65.8 ± 10.2 years, UPDRS total score 48.4 ± 17.1, disease duration 8.5 ± 5.8 years, H&Y stage 2.7 ± 0.8) participated. FOG severity had a significant effect on QoL (P < 0.0015), accounting for disease severity assessed by UPDRS. Specifically, FOG severity was correlated with all the dimensions of the PDQ-39 except for stigma and social support, as follows: with mobility, bodily discomfort, activity of daily living (ADL) (P < 0.005 in all), with emotional, communication, and cognition (P < 0.05 in all). FOG severity (FOG-Q) was also found to affect a modified PDQ total score, without the mobility aspect (P = 0.0081). FOG should be viewed as a highly important symptom with regard to QoL of PD patients beyond its effect on gait and mobility. On the basis of the present results, special attention should be given to FOG in the treatment of patients with PD. |
CC : | 002B17; 002B17G; 002B17F |
FD : | Pathologie du système nerveux; Maladie de Parkinson; Congélation; Qualité de vie; Mobilité |
FG : | Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central |
ED : | Nervous system diseases; Parkinson disease; Freezing; Quality of life; Mobility |
EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease |
SD : | Sistema nervioso patología; Parkinson enfermedad; Congelación; Calidad vida; Movilidad |
LO : | INIST-20953.354000162671070080 |
ID : | 08-0071404 |
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Pascal:08-0071404Le document en format XML
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<front><div type="abstract" xml:lang="en">The aim of this study was to examine the association between freezing of gait (FOG) and quality of life (QoL) in patients with Parkinson's disease (PD). PD patients (n = 118) completed the PDQ-39 (QoL) and FOG-Q questionnaires. Disease severity was assessed by the Hoehn and Yahr (H&Y) staging and the Unified Parkinson's Disease Rating Scale (UPDRS). The relations between those parameters were assessed using regression models. 66 men and 52 women (mean age 65.8 ± 10.2 years, UPDRS total score 48.4 ± 17.1, disease duration 8.5 ± 5.8 years, H&Y stage 2.7 ± 0.8) participated. FOG severity had a significant effect on QoL (P < 0.0015), accounting for disease severity assessed by UPDRS. Specifically, FOG severity was correlated with all the dimensions of the PDQ-39 except for stigma and social support, as follows: with mobility, bodily discomfort, activity of daily living (ADL) (P < 0.005 in all), with emotional, communication, and cognition (P < 0.05 in all). FOG severity (FOG-Q) was also found to affect a modified PDQ total score, without the mobility aspect (P = 0.0081). FOG should be viewed as a highly important symptom with regard to QoL of PD patients beyond its effect on gait and mobility. On the basis of the present results, special attention should be given to FOG in the treatment of patients with PD.</div>
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<ET>Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait</ET>
<AU>MOORE (Orna); PERETZ (Chava); GILADI (Nir)</AU>
<AF>Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center/Tel Aviv/Israël (1 aut., 2 aut., 3 aut.); School of Health Professions, Tel-Aviv University/Tel-Aviv/Israël (2 aut., 3 aut.); Sackler Faculty of Medicine, Tel-Aviv University/Tel-Aviv/Israël (3 aut.)</AF>
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<EA>The aim of this study was to examine the association between freezing of gait (FOG) and quality of life (QoL) in patients with Parkinson's disease (PD). PD patients (n = 118) completed the PDQ-39 (QoL) and FOG-Q questionnaires. Disease severity was assessed by the Hoehn and Yahr (H&Y) staging and the Unified Parkinson's Disease Rating Scale (UPDRS). The relations between those parameters were assessed using regression models. 66 men and 52 women (mean age 65.8 ± 10.2 years, UPDRS total score 48.4 ± 17.1, disease duration 8.5 ± 5.8 years, H&Y stage 2.7 ± 0.8) participated. FOG severity had a significant effect on QoL (P < 0.0015), accounting for disease severity assessed by UPDRS. Specifically, FOG severity was correlated with all the dimensions of the PDQ-39 except for stigma and social support, as follows: with mobility, bodily discomfort, activity of daily living (ADL) (P < 0.005 in all), with emotional, communication, and cognition (P < 0.05 in all). FOG severity (FOG-Q) was also found to affect a modified PDQ total score, without the mobility aspect (P = 0.0081). FOG should be viewed as a highly important symptom with regard to QoL of PD patients beyond its effect on gait and mobility. On the basis of the present results, special attention should be given to FOG in the treatment of patients with PD.</EA>
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