Movement Disorders (revue)

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Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait

Identifieur interne : 001457 ( PascalFrancis/Corpus ); précédent : 001456; suivant : 001458

Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait

Auteurs : Orna Moore ; Chava Peretz ; Nir Giladi

Source :

RBID : Pascal:08-0071404

Descripteurs français

English descriptors

Abstract

The aim of this study was to examine the association between freezing of gait (FOG) and quality of life (QoL) in patients with Parkinson's disease (PD). PD patients (n = 118) completed the PDQ-39 (QoL) and FOG-Q questionnaires. Disease severity was assessed by the Hoehn and Yahr (H&Y) staging and the Unified Parkinson's Disease Rating Scale (UPDRS). The relations between those parameters were assessed using regression models. 66 men and 52 women (mean age 65.8 ± 10.2 years, UPDRS total score 48.4 ± 17.1, disease duration 8.5 ± 5.8 years, H&Y stage 2.7 ± 0.8) participated. FOG severity had a significant effect on QoL (P < 0.0015), accounting for disease severity assessed by UPDRS. Specifically, FOG severity was correlated with all the dimensions of the PDQ-39 except for stigma and social support, as follows: with mobility, bodily discomfort, activity of daily living (ADL) (P < 0.005 in all), with emotional, communication, and cognition (P < 0.05 in all). FOG severity (FOG-Q) was also found to affect a modified PDQ total score, without the mobility aspect (P = 0.0081). FOG should be viewed as a highly important symptom with regard to QoL of PD patients beyond its effect on gait and mobility. On the basis of the present results, special attention should be given to FOG in the treatment of patients with PD.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A03   1    @0 Mov. disord.
A05       @2 22
A06       @2 15
A08 01  1  ENG  @1 Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait
A11 01  1    @1 MOORE (Orna)
A11 02  1    @1 PERETZ (Chava)
A11 03  1    @1 GILADI (Nir)
A14 01      @1 Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center @2 Tel Aviv @3 ISR @Z 1 aut. @Z 2 aut. @Z 3 aut.
A14 02      @1 School of Health Professions, Tel-Aviv University @2 Tel-Aviv @3 ISR @Z 2 aut. @Z 3 aut.
A14 03      @1 Sackler Faculty of Medicine, Tel-Aviv University @2 Tel-Aviv @3 ISR @Z 3 aut.
A20       @1 2192-2195
A21       @1 2007
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000162671070080
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 28 ref.
A47 01  1    @0 08-0071404
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
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C01 01    ENG  @0 The aim of this study was to examine the association between freezing of gait (FOG) and quality of life (QoL) in patients with Parkinson's disease (PD). PD patients (n = 118) completed the PDQ-39 (QoL) and FOG-Q questionnaires. Disease severity was assessed by the Hoehn and Yahr (H&Y) staging and the Unified Parkinson's Disease Rating Scale (UPDRS). The relations between those parameters were assessed using regression models. 66 men and 52 women (mean age 65.8 ± 10.2 years, UPDRS total score 48.4 ± 17.1, disease duration 8.5 ± 5.8 years, H&Y stage 2.7 ± 0.8) participated. FOG severity had a significant effect on QoL (P < 0.0015), accounting for disease severity assessed by UPDRS. Specifically, FOG severity was correlated with all the dimensions of the PDQ-39 except for stigma and social support, as follows: with mobility, bodily discomfort, activity of daily living (ADL) (P < 0.005 in all), with emotional, communication, and cognition (P < 0.05 in all). FOG severity (FOG-Q) was also found to affect a modified PDQ total score, without the mobility aspect (P = 0.0081). FOG should be viewed as a highly important symptom with regard to QoL of PD patients beyond its effect on gait and mobility. On the basis of the present results, special attention should be given to FOG in the treatment of patients with PD.
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C03 01  X  SPA  @0 Sistema nervioso patología @5 01
C03 02  X  FRE  @0 Maladie de Parkinson @2 NM @5 02
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C03 02  X  SPA  @0 Parkinson enfermedad @2 NM @5 02
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C03 03  X  SPA  @0 Congelación @5 09
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C03 04  X  SPA  @0 Calidad vida @5 10
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C03 05  X  SPA  @0 Movilidad @5 11
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C07 01  X  ENG  @0 Cerebral disorder @5 37
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C07 04  X  ENG  @0 Central nervous system disease @5 40
C07 04  X  SPA  @0 Sistema nervosio central patología @5 40
N21       @1 035
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 08-0071404 INIST
ET : Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait
AU : MOORE (Orna); PERETZ (Chava); GILADI (Nir)
AF : Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center/Tel Aviv/Israël (1 aut., 2 aut., 3 aut.); School of Health Professions, Tel-Aviv University/Tel-Aviv/Israël (2 aut., 3 aut.); Sackler Faculty of Medicine, Tel-Aviv University/Tel-Aviv/Israël (3 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 15; Pp. 2192-2195; Bibl. 28 ref.
LA : Anglais
EA : The aim of this study was to examine the association between freezing of gait (FOG) and quality of life (QoL) in patients with Parkinson's disease (PD). PD patients (n = 118) completed the PDQ-39 (QoL) and FOG-Q questionnaires. Disease severity was assessed by the Hoehn and Yahr (H&Y) staging and the Unified Parkinson's Disease Rating Scale (UPDRS). The relations between those parameters were assessed using regression models. 66 men and 52 women (mean age 65.8 ± 10.2 years, UPDRS total score 48.4 ± 17.1, disease duration 8.5 ± 5.8 years, H&Y stage 2.7 ± 0.8) participated. FOG severity had a significant effect on QoL (P < 0.0015), accounting for disease severity assessed by UPDRS. Specifically, FOG severity was correlated with all the dimensions of the PDQ-39 except for stigma and social support, as follows: with mobility, bodily discomfort, activity of daily living (ADL) (P < 0.005 in all), with emotional, communication, and cognition (P < 0.05 in all). FOG severity (FOG-Q) was also found to affect a modified PDQ total score, without the mobility aspect (P = 0.0081). FOG should be viewed as a highly important symptom with regard to QoL of PD patients beyond its effect on gait and mobility. On the basis of the present results, special attention should be given to FOG in the treatment of patients with PD.
CC : 002B17; 002B17G; 002B17F
FD : Pathologie du système nerveux; Maladie de Parkinson; Congélation; Qualité de vie; Mobilité
FG : Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central
ED : Nervous system diseases; Parkinson disease; Freezing; Quality of life; Mobility
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD : Sistema nervioso patología; Parkinson enfermedad; Congelación; Calidad vida; Movilidad
LO : INIST-20953.354000162671070080
ID : 08-0071404

Links to Exploration step

Pascal:08-0071404

Le document en format XML

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<s5>38</s5>
</fC07>
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<s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
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<s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Pathologie du système nerveux central</s0>
<s5>40</s5>
</fC07>
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<s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>40</s5>
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<fN21>
<s1>035</s1>
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<fN44 i1="01">
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<NO>PASCAL 08-0071404 INIST</NO>
<ET>Freezing of Gait Affects Quality of Life of Peoples with Parkinson's Disease Beyond Its Relationships with Mobility and Gait</ET>
<AU>MOORE (Orna); PERETZ (Chava); GILADI (Nir)</AU>
<AF>Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center/Tel Aviv/Israël (1 aut., 2 aut., 3 aut.); School of Health Professions, Tel-Aviv University/Tel-Aviv/Israël (2 aut., 3 aut.); Sackler Faculty of Medicine, Tel-Aviv University/Tel-Aviv/Israël (3 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2007; Vol. 22; No. 15; Pp. 2192-2195; Bibl. 28 ref.</SO>
<LA>Anglais</LA>
<EA>The aim of this study was to examine the association between freezing of gait (FOG) and quality of life (QoL) in patients with Parkinson's disease (PD). PD patients (n = 118) completed the PDQ-39 (QoL) and FOG-Q questionnaires. Disease severity was assessed by the Hoehn and Yahr (H&Y) staging and the Unified Parkinson's Disease Rating Scale (UPDRS). The relations between those parameters were assessed using regression models. 66 men and 52 women (mean age 65.8 ± 10.2 years, UPDRS total score 48.4 ± 17.1, disease duration 8.5 ± 5.8 years, H&Y stage 2.7 ± 0.8) participated. FOG severity had a significant effect on QoL (P < 0.0015), accounting for disease severity assessed by UPDRS. Specifically, FOG severity was correlated with all the dimensions of the PDQ-39 except for stigma and social support, as follows: with mobility, bodily discomfort, activity of daily living (ADL) (P < 0.005 in all), with emotional, communication, and cognition (P < 0.05 in all). FOG severity (FOG-Q) was also found to affect a modified PDQ total score, without the mobility aspect (P = 0.0081). FOG should be viewed as a highly important symptom with regard to QoL of PD patients beyond its effect on gait and mobility. On the basis of the present results, special attention should be given to FOG in the treatment of patients with PD.</EA>
<CC>002B17; 002B17G; 002B17F</CC>
<FD>Pathologie du système nerveux; Maladie de Parkinson; Congélation; Qualité de vie; Mobilité</FD>
<FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central</FG>
<ED>Nervous system diseases; Parkinson disease; Freezing; Quality of life; Mobility</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease</EG>
<SD>Sistema nervioso patología; Parkinson enfermedad; Congelación; Calidad vida; Movilidad</SD>
<LO>INIST-20953.354000162671070080</LO>
<ID>08-0071404</ID>
</server>
</inist>
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