Decision Making in Parkinson's Disease : Analysis of Behavioral and Physiological Patterns in the Iowa Gambling Task
Identifieur interne : 001319 ( PascalFrancis/Corpus ); précédent : 001318; suivant : 001320Decision Making in Parkinson's Disease : Analysis of Behavioral and Physiological Patterns in the Iowa Gambling Task
Auteurs : Mutsutaka Kobayakawa ; Shinichi Koyama ; Masaru Mimura ; Mitsuru KawamuraSource :
- Movement disorders [ 0885-3185 ] ; 2008.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Recent studies suggest that social recognition processes are affected by Parkinson's disease (PD). However, whether PD patients exhibit behavioral changes is still controversial. The purpose of the present study was to examine the decision making of PD patients performing the Iowa Gambling Task (IGT). We recruited a large number of early, nondemented PD patients for the IGT. We also recorded the skin conductance responses (SCRs) during the task as a measure of emotional arousal. Compared with the normal control (NC) subjects, PD patients selected more disadvantageous decks in the IGT, and their SCRs were lower than those of NC subjects before making decisions and after receiving reward or punishment. The tendency toward risky choices was not correlated with age, education, global cognitive function, or the severity of the disease. These results confirmed that the decision making of PD patients was affected by the disease, rather than by other cognitive functions; moreover, such behavior was related to lower emotional responses. Behavioral and SCR patterns of PD patients were similar to those of amygdala-damaged patients. The response bias toward risky choices in PD may be explained by the dysfunction of the amygdala, which is known to be involved in risk evaluation.
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Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 08-0199273 INIST |
---|---|
ET : | Decision Making in Parkinson's Disease : Analysis of Behavioral and Physiological Patterns in the Iowa Gambling Task |
AU : | KOBAYAKAWA (Mutsutaka); KOYAMA (Shinichi); MIMURA (Masaru); KAWAMURA (Mitsuru) |
AF : | Department of Neurology, Showa University School of Medicine/Tokyo/Japon (1 aut., 2 aut., 4 aut.); Design Psychology Unit, Department of Design Science, Graduate School of Engineering, Chiba University/Chiba/Japon (2 aut.); Department of Neuropsychiatry, Showa University School of Medicine/Tokyo/Japon (3 aut.); Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST)/Saitama/Japon (4 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 4; Pp. 547-552; Bibl. 35 ref. |
LA : | Anglais |
EA : | Recent studies suggest that social recognition processes are affected by Parkinson's disease (PD). However, whether PD patients exhibit behavioral changes is still controversial. The purpose of the present study was to examine the decision making of PD patients performing the Iowa Gambling Task (IGT). We recruited a large number of early, nondemented PD patients for the IGT. We also recorded the skin conductance responses (SCRs) during the task as a measure of emotional arousal. Compared with the normal control (NC) subjects, PD patients selected more disadvantageous decks in the IGT, and their SCRs were lower than those of NC subjects before making decisions and after receiving reward or punishment. The tendency toward risky choices was not correlated with age, education, global cognitive function, or the severity of the disease. These results confirmed that the decision making of PD patients was affected by the disease, rather than by other cognitive functions; moreover, such behavior was related to lower emotional responses. Behavioral and SCR patterns of PD patients were similar to those of amygdala-damaged patients. The response bias toward risky choices in PD may be explained by the dysfunction of the amygdala, which is known to be involved in risk evaluation. |
CC : | 002B17; 002B17G |
FD : | Maladie de Parkinson; Pathologie du système nerveux; Prise de décision; Analyse comportementale; Peau; Cognition |
FG : | Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central |
ED : | Parkinson disease; Nervous system diseases; Decision making; Behavioral analysis; Skin; Cognition |
EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease |
SD : | Parkinson enfermedad; Sistema nervioso patología; Toma decision; Análisis conductual; Piel; Cognición |
LO : | INIST-20953.354000183361080090 |
ID : | 08-0199273 |
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Pascal:08-0199273Le document en format XML
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<front><div type="abstract" xml:lang="en">Recent studies suggest that social recognition processes are affected by Parkinson's disease (PD). However, whether PD patients exhibit behavioral changes is still controversial. The purpose of the present study was to examine the decision making of PD patients performing the Iowa Gambling Task (IGT). We recruited a large number of early, nondemented PD patients for the IGT. We also recorded the skin conductance responses (SCRs) during the task as a measure of emotional arousal. Compared with the normal control (NC) subjects, PD patients selected more disadvantageous decks in the IGT, and their SCRs were lower than those of NC subjects before making decisions and after receiving reward or punishment. The tendency toward risky choices was not correlated with age, education, global cognitive function, or the severity of the disease. These results confirmed that the decision making of PD patients was affected by the disease, rather than by other cognitive functions; moreover, such behavior was related to lower emotional responses. Behavioral and SCR patterns of PD patients were similar to those of amygdala-damaged patients. The response bias toward risky choices in PD may be explained by the dysfunction of the amygdala, which is known to be involved in risk evaluation.</div>
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<ET>Decision Making in Parkinson's Disease : Analysis of Behavioral and Physiological Patterns in the Iowa Gambling Task</ET>
<AU>KOBAYAKAWA (Mutsutaka); KOYAMA (Shinichi); MIMURA (Masaru); KAWAMURA (Mitsuru)</AU>
<AF>Department of Neurology, Showa University School of Medicine/Tokyo/Japon (1 aut., 2 aut., 4 aut.); Design Psychology Unit, Department of Design Science, Graduate School of Engineering, Chiba University/Chiba/Japon (2 aut.); Department of Neuropsychiatry, Showa University School of Medicine/Tokyo/Japon (3 aut.); Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST)/Saitama/Japon (4 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 4; Pp. 547-552; Bibl. 35 ref.</SO>
<LA>Anglais</LA>
<EA>Recent studies suggest that social recognition processes are affected by Parkinson's disease (PD). However, whether PD patients exhibit behavioral changes is still controversial. The purpose of the present study was to examine the decision making of PD patients performing the Iowa Gambling Task (IGT). We recruited a large number of early, nondemented PD patients for the IGT. We also recorded the skin conductance responses (SCRs) during the task as a measure of emotional arousal. Compared with the normal control (NC) subjects, PD patients selected more disadvantageous decks in the IGT, and their SCRs were lower than those of NC subjects before making decisions and after receiving reward or punishment. The tendency toward risky choices was not correlated with age, education, global cognitive function, or the severity of the disease. These results confirmed that the decision making of PD patients was affected by the disease, rather than by other cognitive functions; moreover, such behavior was related to lower emotional responses. Behavioral and SCR patterns of PD patients were similar to those of amygdala-damaged patients. The response bias toward risky choices in PD may be explained by the dysfunction of the amygdala, which is known to be involved in risk evaluation.</EA>
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