MovDisordV3, PascalFrancis, Corpus, bibRecord, 001237

Evaluation of a Screening Instrument for Essential Tremor

Identifieur interne : 001237 ( PascalFrancis/Corpus ); précédent : 001236; suivant : 001238

Evaluation of a Screening Instrument for Essential Tremor

Auteurs : Delia Lorenz ; Frank Papengut ; Henrik Frederiksen ; Florian Kopper ; Stephan Klebe ; Kaare Christensen ; Stefan Schreiber ; Günther Deuschl

Source :

Movement disorders [ 0885-3185 ] ; 2008.

RBID : Pascal:08-0305145

Descripteurs français

Pascal (Inist)
- Tremblement, Pathologie du système nerveux, Evaluation, Dépistage, Instrument, Spirale.

English descriptors

KwdEn :
- Evaluation, Instrument, Medical screening, Nervous system diseases, Spiral, Tremor.

Abstract

To evaluate a screening instrument for essential tremor (ET) consisting of a seven-item questionnaire and a spiral drawing. A total of 2,448 Danish twins aged 70 years or more and a second sample aged 60 years or more (n = 1,684) from a population-based northern German cross-sectional study (PopGen ET) were screened for ET. Inclusion criteria were a previous diagnosis of ET, a positive answer to two or more questions of the questionnaire or a spiral rating >4 (range of scale 0-9). Three hundred thirteen of 380 positively screened and 321 negatively screened subjects were clinically examined. Definite or probable ET was diagnosed in 104 patients, possible in 86 and other tremors in 98 patients. The sensitivity of the screening instrument was 70.5%, the positive predictive value was 64.9%, the specificity was 68.2%, and the negative predictive value was 73.5%. Tremor severity correlated significantly with higher spiral scores and more positive items. More patients were identified by spiral drawing in all tremor groups. The interrater and intrarater reliability for spirals ranged from 0.7 to 0.8 using intraclass coefficient. A cluster analysis revealed that the questionnaire can be reduced to three items, about uncontrollable tremor in any body part, tremor while drinking or pouring and other family members with tremor, without loosing efficacy. We present an easy to use and reliable screening instrument that is effective to identify patients with ET but not able to exclude patients with other tremor forms.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A11	`02`	`1`		`@1 PAPENGUT (Frank)`
A11	`03`	`1`		`@1 FREDERIKSEN (Henrik)`
A11	`04`	`1`		`@1 KOPPER (Florian)`
A11	`05`	`1`		`@1 KLEBE (Stephan)`
A11	`06`	`1`		`@1 CHRISTENSEN (Kaare)`
A11	`07`	`1`		`@1 SCHREIBER (Stefan)`
A11	`08`	`1`		`@1 DEUSCHL (Günther)`
A14	`01`			`@1 Department of Neurology, Christian-Albrechts-University Kiel @3 DEU @Z 1 aut. @Z 2 aut. @Z 4 aut. @Z 5 aut. @Z 8 aut.`
A14	`02`			`@1 The Danish Twin Registry, Epidemiology, Institute of Public Health, University of SouthernDenmark @3 DNK @Z 3 aut. @Z 6 aut.`
A14	`03`			`@1 Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel @2 Kiel @3 DEU @Z 7 aut.`
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A44				`@0 0000 @1 © 2008 INIST-CNRS. All rights reserved.`
A45				`@0 20 ref.`
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C01	`01`		`ENG`	@0 To evaluate a screening instrument for essential tremor (ET) consisting of a seven-item questionnaire and a spiral drawing. A total of 2,448 Danish twins aged 70 years or more and a second sample aged 60 years or more (n = 1,684) from a population-based northern German cross-sectional study (PopGen ET) were screened for ET. Inclusion criteria were a previous diagnosis of ET, a positive answer to two or more questions of the questionnaire or a spiral rating >4 (range of scale 0-9). Three hundred thirteen of 380 positively screened and 321 negatively screened subjects were clinically examined. Definite or probable ET was diagnosed in 104 patients, possible in 86 and other tremors in 98 patients. The sensitivity of the screening instrument was 70.5%, the positive predictive value was 64.9%, the specificity was 68.2%, and the negative predictive value was 73.5%. Tremor severity correlated significantly with higher spiral scores and more positive items. More patients were identified by spiral drawing in all tremor groups. The interrater and intrarater reliability for spirals ranged from 0.7 to 0.8 using intraclass coefficient. A cluster analysis revealed that the questionnaire can be reduced to three items, about uncontrollable tremor in any body part, tremor while drinking or pouring and other family members with tremor, without loosing efficacy. We present an easy to use and reliable screening instrument that is effective to identify patients with ET but not able to exclude patients with other tremor forms.
C02	`01`	`X`		`@0 002B17`
C02	`02`	`X`		`@0 002B17A01`
C03	`01`	`X`	`FRE`	`@0 Tremblement @5 01`
C03	`01`	`X`	`ENG`	`@0 Tremor @5 01`
C03	`01`	`X`	`SPA`	`@0 Temblor @5 01`
C03	`02`	`X`	`FRE`	`@0 Pathologie du système nerveux @5 02`
C03	`02`	`X`	`ENG`	`@0 Nervous system diseases @5 02`
C03	`02`	`X`	`SPA`	`@0 Sistema nervioso patología @5 02`
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C03	`03`	`X`	`ENG`	`@0 Evaluation @5 09`
C03	`03`	`X`	`SPA`	`@0 Evaluación @5 09`
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C03	`04`	`X`	`ENG`	`@0 Medical screening @5 10`
C03	`04`	`X`	`SPA`	`@0 Descubrimiento @5 10`
C03	`05`	`X`	`FRE`	`@0 Instrument @5 11`
C03	`05`	`X`	`ENG`	`@0 Instrument @5 11`
C03	`05`	`X`	`SPA`	`@0 Instrumento @5 11`
C03	`06`	`X`	`FRE`	`@0 Spirale @5 12`
C03	`06`	`X`	`ENG`	`@0 Spiral @5 12`
C03	`06`	`X`	`SPA`	`@0 Espira @5 12`
C07	`01`	`X`	`FRE`	`@0 Mouvement involontaire @5 37`
C07	`01`	`X`	`ENG`	`@0 Involuntary movement @5 37`
C07	`01`	`X`	`SPA`	`@0 Movimiento involuntario @5 37`
C07	`02`	`X`	`FRE`	`@0 Trouble neurologique @5 39`
C07	`02`	`X`	`ENG`	`@0 Neurological disorder @5 39`
C07	`02`	`X`	`SPA`	`@0 Trastorno neurológico @5 39`
N21				`@1 189`
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Format Inist (serveur)

NO :	PASCAL 08-0305145 INIST
ET :	Evaluation of a Screening Instrument for Essential Tremor
AU :	LORENZ (Delia); PAPENGUT (Frank); FREDERIKSEN (Henrik); KOPPER (Florian); KLEBE (Stephan); CHRISTENSEN (Kaare); SCHREIBER (Stefan); DEUSCHL (Günther)
AF :	Department of Neurology, Christian-Albrechts-University Kiel/Allemagne (1 aut., 2 aut., 4 aut., 5 aut., 8 aut.); The Danish Twin Registry, Epidemiology, Institute of Public Health, University of SouthernDenmark/Danemark (3 aut., 6 aut.); Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel/Kiel/Allemagne (7 aut.)
DT :	Publication en série; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 7; Pp. 1006-1012; Bibl. 20 ref.
LA :	Anglais
EA :	To evaluate a screening instrument for essential tremor (ET) consisting of a seven-item questionnaire and a spiral drawing. A total of 2,448 Danish twins aged 70 years or more and a second sample aged 60 years or more (n = 1,684) from a population-based northern German cross-sectional study (PopGen ET) were screened for ET. Inclusion criteria were a previous diagnosis of ET, a positive answer to two or more questions of the questionnaire or a spiral rating >4 (range of scale 0-9). Three hundred thirteen of 380 positively screened and 321 negatively screened subjects were clinically examined. Definite or probable ET was diagnosed in 104 patients, possible in 86 and other tremors in 98 patients. The sensitivity of the screening instrument was 70.5%, the positive predictive value was 64.9%, the specificity was 68.2%, and the negative predictive value was 73.5%. Tremor severity correlated significantly with higher spiral scores and more positive items. More patients were identified by spiral drawing in all tremor groups. The interrater and intrarater reliability for spirals ranged from 0.7 to 0.8 using intraclass coefficient. A cluster analysis revealed that the questionnaire can be reduced to three items, about uncontrollable tremor in any body part, tremor while drinking or pouring and other family members with tremor, without loosing efficacy. We present an easy to use and reliable screening instrument that is effective to identify patients with ET but not able to exclude patients with other tremor forms.
CC :	002B17; 002B17A01
FD :	Tremblement; Pathologie du système nerveux; Evaluation; Dépistage; Instrument; Spirale
FG :	Mouvement involontaire; Trouble neurologique
ED :	Tremor; Nervous system diseases; Evaluation; Medical screening; Instrument; Spiral
EG :	Involuntary movement; Neurological disorder
SD :	Temblor; Sistema nervioso patología; Evaluación; Descubrimiento; Instrumento; Espira
LO :	INIST-20953.354000200276040120
ID :	08-0305145

Links to Exploration step

Pascal:08-0305145

Le document en format XML

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<front><div type="abstract" xml:lang="en">To evaluate a screening instrument for essential tremor (ET) consisting of a seven-item questionnaire and a spiral drawing. A total of 2,448 Danish twins aged 70 years or more and a second sample aged 60 years or more (n = 1,684) from a population-based northern German cross-sectional study (PopGen ET) were screened for ET. Inclusion criteria were a previous diagnosis of ET, a positive answer to two or more questions of the questionnaire or a spiral rating >4 (range of scale 0-9). Three hundred thirteen of 380 positively screened and 321 negatively screened subjects were clinically examined. Definite or probable ET was diagnosed in 104 patients, possible in 86 and other tremors in 98 patients. The sensitivity of the screening instrument was 70.5%, the positive predictive value was 64.9%, the specificity was 68.2%, and the negative predictive value was 73.5%. Tremor severity correlated significantly with higher spiral scores and more positive items. More patients were identified by spiral drawing in all tremor groups. The interrater and intrarater reliability for spirals ranged from 0.7 to 0.8 using intraclass coefficient. A cluster analysis revealed that the questionnaire can be reduced to three items, about uncontrollable tremor in any body part, tremor while drinking or pouring and other family members with tremor, without loosing efficacy. We present an easy to use and reliable screening instrument that is effective to identify patients with ET but not able to exclude patients with other tremor forms.</div>
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<fC01 i1="01" l="ENG"><s0>To evaluate a screening instrument for essential tremor (ET) consisting of a seven-item questionnaire and a spiral drawing. A total of 2,448 Danish twins aged 70 years or more and a second sample aged 60 years or more (n = 1,684) from a population-based northern German cross-sectional study (PopGen ET) were screened for ET. Inclusion criteria were a previous diagnosis of ET, a positive answer to two or more questions of the questionnaire or a spiral rating >4 (range of scale 0-9). Three hundred thirteen of 380 positively screened and 321 negatively screened subjects were clinically examined. Definite or probable ET was diagnosed in 104 patients, possible in 86 and other tremors in 98 patients. The sensitivity of the screening instrument was 70.5%, the positive predictive value was 64.9%, the specificity was 68.2%, and the negative predictive value was 73.5%. Tremor severity correlated significantly with higher spiral scores and more positive items. More patients were identified by spiral drawing in all tremor groups. The interrater and intrarater reliability for spirals ranged from 0.7 to 0.8 using intraclass coefficient. A cluster analysis revealed that the questionnaire can be reduced to three items, about uncontrollable tremor in any body part, tremor while drinking or pouring and other family members with tremor, without loosing efficacy. We present an easy to use and reliable screening instrument that is effective to identify patients with ET but not able to exclude patients with other tremor forms.</s0>
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<fC02 i1="01" i2="X"><s0>002B17</s0>
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<s5>01</s5>
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<fC03 i1="01" i2="X" l="ENG"><s0>Tremor</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Temblor</s0>
<s5>01</s5>
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<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Evaluación</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Dépistage</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Medical screening</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Descubrimiento</s0>
<s5>10</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Instrument</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Instrument</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Instrumento</s0>
<s5>11</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Spirale</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Spiral</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Espira</s0>
<s5>12</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Mouvement involontaire</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Involuntary movement</s0>
<s5>37</s5>
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<s5>37</s5>
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<fC07 i1="02" i2="X" l="FRE"><s0>Trouble neurologique</s0>
<s5>39</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Neurological disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Trastorno neurológico</s0>
<s5>39</s5>
</fC07>
<fN21><s1>189</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
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<server><NO>PASCAL 08-0305145 INIST</NO>
<ET>Evaluation of a Screening Instrument for Essential Tremor</ET>
<AU>LORENZ (Delia); PAPENGUT (Frank); FREDERIKSEN (Henrik); KOPPER (Florian); KLEBE (Stephan); CHRISTENSEN (Kaare); SCHREIBER (Stefan); DEUSCHL (Günther)</AU>
<AF>Department of Neurology, Christian-Albrechts-University Kiel/Allemagne (1 aut., 2 aut., 4 aut., 5 aut., 8 aut.); The Danish Twin Registry, Epidemiology, Institute of Public Health, University of SouthernDenmark/Danemark (3 aut., 6 aut.); Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Campus Kiel/Kiel/Allemagne (7 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 7; Pp. 1006-1012; Bibl. 20 ref.</SO>
<LA>Anglais</LA>
<EA>To evaluate a screening instrument for essential tremor (ET) consisting of a seven-item questionnaire and a spiral drawing. A total of 2,448 Danish twins aged 70 years or more and a second sample aged 60 years or more (n = 1,684) from a population-based northern German cross-sectional study (PopGen ET) were screened for ET. Inclusion criteria were a previous diagnosis of ET, a positive answer to two or more questions of the questionnaire or a spiral rating >4 (range of scale 0-9). Three hundred thirteen of 380 positively screened and 321 negatively screened subjects were clinically examined. Definite or probable ET was diagnosed in 104 patients, possible in 86 and other tremors in 98 patients. The sensitivity of the screening instrument was 70.5%, the positive predictive value was 64.9%, the specificity was 68.2%, and the negative predictive value was 73.5%. Tremor severity correlated significantly with higher spiral scores and more positive items. More patients were identified by spiral drawing in all tremor groups. The interrater and intrarater reliability for spirals ranged from 0.7 to 0.8 using intraclass coefficient. A cluster analysis revealed that the questionnaire can be reduced to three items, about uncontrollable tremor in any body part, tremor while drinking or pouring and other family members with tremor, without loosing efficacy. We present an easy to use and reliable screening instrument that is effective to identify patients with ET but not able to exclude patients with other tremor forms.</EA>
<CC>002B17; 002B17A01</CC>
<FD>Tremblement; Pathologie du   système nerveux; Evaluation; Dépistage; Instrument; Spirale</FD>
<FG>Mouvement involontaire; Trouble neurologique</FG>
<ED>Tremor; Nervous system diseases; Evaluation; Medical screening; Instrument; Spiral</ED>
<EG>Involuntary movement; Neurological disorder</EG>
<SD>Temblor; Sistema nervioso patología; Evaluación; Descubrimiento; Instrumento; Espira</SD>
<LO>INIST-20953.354000200276040120</LO>
<ID>08-0305145</ID>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Evaluation of a Screening Instrument for Essential Tremor

Evaluation of a Screening Instrument for Essential Tremor

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