MovDisordV3, PascalFrancis, Corpus, bibRecord, 001186

The Role of Gait Rhythmicity and Bilateral Coordination of Stepping in the Pathophysiology of Freezing of Gait in Parkinson's Disease

Identifieur interne : 001186 ( PascalFrancis/Corpus ); précédent : 001185; suivant : 001187

The Role of Gait Rhythmicity and Bilateral Coordination of Stepping in the Pathophysiology of Freezing of Gait in Parkinson's Disease

Auteurs : Meir Plotnik ; Jeffrey M. Hausdorff

Source :

Movement disorders [ 0885-3185 ] ; 2008.

RBID : Pascal:08-0414962

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Pathologie du système nerveux, Coordination, Physiopathologie, Congélation, Asymétrie.

English descriptors

KwdEn :
- Asymmetry, Coordination, Freezing, Nervous system diseases, Parkinson disease, Pathophysiology.

Abstract

Freezing of gait (FOG) is a disabling episodic gait disturbance that is common among patients with Parkinson's disease (PD). In this review, we describe a new approach for understanding the mechanisms underlying this puzzling phenomenon. We propose that impairments in the ongoing regulation of gait, even during periods in which freezing is not present, set the stage for the occurrence of a FOG episode. More specifically, three "interictal" walking attributes are associated with FOG: gait rhythmicity, gait asymmetry, and bilateral dyscoordination of left-right stepping. Gait is less rhythmic, more asymmetric, and less coordinated among PD patients with FOG, when compared with PD patients without FOG. We describe the relationship between these changes and other features of patients with FOG and discuss whether these gait changes may predispose to FOG or if they also cause FOG, perhaps, when they are altered beyond a certain threshold or exacerbated by another trigger.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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C01	`01`		`ENG`	@0 Freezing of gait (FOG) is a disabling episodic gait disturbance that is common among patients with Parkinson's disease (PD). In this review, we describe a new approach for understanding the mechanisms underlying this puzzling phenomenon. We propose that impairments in the ongoing regulation of gait, even during periods in which freezing is not present, set the stage for the occurrence of a FOG episode. More specifically, three "interictal" walking attributes are associated with FOG: gait rhythmicity, gait asymmetry, and bilateral dyscoordination of left-right stepping. Gait is less rhythmic, more asymmetric, and less coordinated among PD patients with FOG, when compared with PD patients without FOG. We describe the relationship between these changes and other features of patients with FOG and discuss whether these gait changes may predispose to FOG or if they also cause FOG, perhaps, when they are altered beyond a certain threshold or exacerbated by another trigger.
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Format Inist (serveur)

NO :	PASCAL 08-0414962 INIST
ET :	The Role of Gait Rhythmicity and Bilateral Coordination of Stepping in the Pathophysiology of Freezing of Gait in Parkinson's Disease
AU :	PLOTNIK (Meir); HAUSDORFF (Jeffrey M.); GILADI (Nir); NIEUWBOER (Alice)
AF :	Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center/Tel-Aviv/Israël (1 aut., 2 aut.); Department of Physical Therapy, Sackler Faculty of Medicine, Tel-Aviv University/Tel-Aviv/Israël (2 aut.); Division on Aging, Harvard Medical School/Boston, Massachusetts/Etats-Unis (2 aut.); Department of Neurology, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University/Tel-Aviv/Israël (1 aut.); Department Revalidatiewetenschappen Faculteit Bewegings- en Revalidatiewetenschappen, Katholieke Universiteit Leuven/Leuven (Heverlee)/Belgique (2 aut.)
DT :	Publication en série; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. SUP2; S444-S450; Bibl. 34 ref.
LA :	Anglais
EA :	Freezing of gait (FOG) is a disabling episodic gait disturbance that is common among patients with Parkinson's disease (PD). In this review, we describe a new approach for understanding the mechanisms underlying this puzzling phenomenon. We propose that impairments in the ongoing regulation of gait, even during periods in which freezing is not present, set the stage for the occurrence of a FOG episode. More specifically, three "interictal" walking attributes are associated with FOG: gait rhythmicity, gait asymmetry, and bilateral dyscoordination of left-right stepping. Gait is less rhythmic, more asymmetric, and less coordinated among PD patients with FOG, when compared with PD patients without FOG. We describe the relationship between these changes and other features of patients with FOG and discuss whether these gait changes may predispose to FOG or if they also cause FOG, perhaps, when they are altered beyond a certain threshold or exacerbated by another trigger.
CC :	002B17; 002B17G
FD :	Maladie de Parkinson; Pathologie du système nerveux; Coordination; Physiopathologie; Congélation; Asymétrie
FG :	Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central
ED :	Parkinson disease; Nervous system diseases; Coordination; Pathophysiology; Freezing; Asymmetry
EG :	Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD :	Parkinson enfermedad; Sistema nervioso patología; Coordinación; Fisiopatología; Congelación; Asimetría
LO :	INIST-20953.354000196264240040
ID :	08-0414962

Links to Exploration step

Pascal:08-0414962

Le document en format XML

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<front><div type="abstract" xml:lang="en">Freezing of gait (FOG) is a disabling episodic gait disturbance that is common among patients with Parkinson's disease (PD). In this review, we describe a new approach for understanding the mechanisms underlying this puzzling phenomenon. We propose that impairments in the ongoing regulation of gait, even during periods in which freezing is not present, set the stage for the occurrence of a FOG episode. More specifically, three "interictal" walking attributes are associated with FOG: gait rhythmicity, gait asymmetry, and bilateral dyscoordination of left-right stepping. Gait is less rhythmic, more asymmetric, and less coordinated among PD patients with FOG, when compared with PD patients without FOG. We describe the relationship between these changes and other features of patients with FOG and discuss whether these gait changes may predispose to FOG or if they also cause FOG, perhaps, when they are altered beyond a certain threshold or exacerbated by another trigger.</div>
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<server><NO>PASCAL 08-0414962 INIST</NO>
<ET>The Role of Gait Rhythmicity and Bilateral Coordination of Stepping in the Pathophysiology of Freezing of Gait in Parkinson's Disease</ET>
<AU>PLOTNIK (Meir); HAUSDORFF (Jeffrey M.); GILADI (Nir); NIEUWBOER (Alice)</AU>
<AF>Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center/Tel-Aviv/Israël (1 aut., 2 aut.); Department of Physical Therapy, Sackler Faculty of Medicine, Tel-Aviv University/Tel-Aviv/Israël (2 aut.); Division on Aging, Harvard Medical School/Boston, Massachusetts/Etats-Unis (2 aut.); Department of Neurology, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University/Tel-Aviv/Israël (1 aut.); Department Revalidatiewetenschappen Faculteit Bewegings- en Revalidatiewetenschappen, Katholieke Universiteit Leuven/Leuven (Heverlee)/Belgique (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. SUP2; S444-S450; Bibl. 34 ref.</SO>
<LA>Anglais</LA>
<EA>Freezing of gait (FOG) is a disabling episodic gait disturbance that is common among patients with Parkinson's disease (PD). In this review, we describe a new approach for understanding the mechanisms underlying this puzzling phenomenon. We propose that impairments in the ongoing regulation of gait, even during periods in which freezing is not present, set the stage for the occurrence of a FOG episode. More specifically, three "interictal" walking attributes are associated with FOG: gait rhythmicity, gait asymmetry, and bilateral dyscoordination of left-right stepping. Gait is less rhythmic, more asymmetric, and less coordinated among PD patients with FOG, when compared with PD patients without FOG. We describe the relationship between these changes and other features of patients with FOG and discuss whether these gait changes may predispose to FOG or if they also cause FOG, perhaps, when they are altered beyond a certain threshold or exacerbated by another trigger.</EA>
<CC>002B17; 002B17G</CC>
<FD>Maladie de Parkinson; Pathologie du   système nerveux; Coordination; Physiopathologie; Congélation; Asymétrie</FD>
<FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du   système nerveux central</FG>
<ED>Parkinson disease; Nervous system diseases; Coordination; Pathophysiology; Freezing; Asymmetry</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease</EG>
<SD>Parkinson enfermedad; Sistema nervioso patología; Coordinación; Fisiopatología; Congelación; Asimetría</SD>
<LO>INIST-20953.354000196264240040</LO>
<ID>08-0414962</ID>
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	Movement Disorders (revue)
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Movement Disorders (revue)

The Role of Gait Rhythmicity and Bilateral Coordination of Stepping in the Pathophysiology of Freezing of Gait in Parkinson's Disease

The Role of Gait Rhythmicity and Bilateral Coordination of Stepping in the Pathophysiology of Freezing of Gait in Parkinson's Disease

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