Movement Disorders (revue)

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Effect of External Cueing on Gait in Huntington's Disease

Identifieur interne : 001169 ( PascalFrancis/Corpus ); précédent : 001168; suivant : 001170

Effect of External Cueing on Gait in Huntington's Disease

Auteurs : Arnaud Delval ; Pierre Krystkowiak ; Marie Delliaux ; Jean-Louis Blatt ; Philippe Derambure ; Alain Destee ; Luc Defebvre

Source :

RBID : Pascal:08-0417076

Descripteurs français

English descriptors

Abstract

In Huntington's disease (HD) patients, gait is characterized by a timing disorder with marked intraindividual variability in temporal gait parameters (caused by the presence of both hyperkinetic and hypokinetic features). We sought to determine the influence of use of a metronome on gait parameters in patients simultaneously performing motor or cognitive tasks that required attentional resources. The objective is to evaluate the influence of rhythmic cues on gait interference during self-regulated walking and a dual task paradigm in HD. Fifteen HD patients and 15 paired controls were asked to walk and simultaneously perform another motor task (carrying a tray with four full glasses) or a cognitive task (counting backwards). We evaluated the effect of a metronome (set at 100% and 120% of the subject's self-determined cadence) in three different task conditions (gait alone, gait + motor task, gait + cognitive task). The use of auditory cues during free gait and dual tasks did not improve kinematic parameters in HD patients, in contrast to the situation for control subjects (improvement in gait speed and cadence but not stride length when the metronome was set at 120% in all conditions). HD patients have difficulty in synchronizing their footsteps with a metronome, mainly due to attentional deficits.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 23
A06       @2 10
A08 01  1  ENG  @1 Effect of External Cueing on Gait in Huntington's Disease
A11 01  1    @1 DELVAL (Arnaud)
A11 02  1    @1 KRYSTKOWIAK (Pierre)
A11 03  1    @1 DELLIAUX (Marie)
A11 04  1    @1 BLATT (Jean-Louis)
A11 05  1    @1 DERAMBURE (Philippe)
A11 06  1    @1 DESTEE (Alain)
A11 07  1    @1 DEFEBVRE (Luc)
A14 01      @1 Department of Neurology and Movement Disorders, EA 2683, IFR 114, Salengro Hospital, Lille Regional University Hospital @3 FRA @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 6 aut. @Z 7 aut.
A14 02      @1 Department of Clinical Neurophysiology, EA 2683, IFR 114, Salengro Hospital, Lille Regional University Hospital @3 FRA @Z 1 aut. @Z 4 aut. @Z 5 aut.
A20       @1 1446-1452
A21       @1 2008
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000196364640140
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 19 ref.
A47 01  1    @0 08-0417076
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
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C01 01    ENG  @0 In Huntington's disease (HD) patients, gait is characterized by a timing disorder with marked intraindividual variability in temporal gait parameters (caused by the presence of both hyperkinetic and hypokinetic features). We sought to determine the influence of use of a metronome on gait parameters in patients simultaneously performing motor or cognitive tasks that required attentional resources. The objective is to evaluate the influence of rhythmic cues on gait interference during self-regulated walking and a dual task paradigm in HD. Fifteen HD patients and 15 paired controls were asked to walk and simultaneously perform another motor task (carrying a tray with four full glasses) or a cognitive task (counting backwards). We evaluated the effect of a metronome (set at 100% and 120% of the subject's self-determined cadence) in three different task conditions (gait alone, gait + motor task, gait + cognitive task). The use of auditory cues during free gait and dual tasks did not improve kinematic parameters in HD patients, in contrast to the situation for control subjects (improvement in gait speed and cadence but not stride length when the metronome was set at 120% in all conditions). HD patients have difficulty in synchronizing their footsteps with a metronome, mainly due to attentional deficits.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C03 01  X  FRE  @0 Chorée de Huntington @5 01
C03 01  X  ENG  @0 Huntington disease @5 01
C03 01  X  SPA  @0 Corea Huntington @5 01
C03 02  X  FRE  @0 Pathologie du système nerveux @5 02
C03 02  X  ENG  @0 Nervous system diseases @5 02
C03 02  X  SPA  @0 Sistema nervioso patología @5 02
C03 03  X  FRE  @0 Noyau gris central @5 09
C03 03  X  ENG  @0 Basal ganglion @5 09
C03 03  X  SPA  @0 Núcleo basal @5 09
C07 01  X  FRE  @0 Pathologie de l'encéphale @5 37
C07 01  X  ENG  @0 Cerebral disorder @5 37
C07 01  X  SPA  @0 Encéfalo patología @5 37
C07 02  X  FRE  @0 Syndrome extrapyramidal @5 38
C07 02  X  ENG  @0 Extrapyramidal syndrome @5 38
C07 02  X  SPA  @0 Extrapiramidal síndrome @5 38
C07 03  X  FRE  @0 Maladie dégénérative @5 39
C07 03  X  ENG  @0 Degenerative disease @5 39
C07 03  X  SPA  @0 Enfermedad degenerativa @5 39
C07 04  X  FRE  @0 Maladie héréditaire @5 40
C07 04  X  ENG  @0 Genetic disease @5 40
C07 04  X  SPA  @0 Enfermedad hereditaria @5 40
C07 05  X  FRE  @0 Pathologie du système nerveux central @5 41
C07 05  X  ENG  @0 Central nervous system disease @5 41
C07 05  X  SPA  @0 Sistema nervosio central patología @5 41
C07 06  X  FRE  @0 Encéphale @5 43
C07 06  X  ENG  @0 Encephalon @5 43
C07 06  X  SPA  @0 Encéfalo @5 43
C07 07  X  FRE  @0 Système nerveux central @5 44
C07 07  X  ENG  @0 Central nervous system @5 44
C07 07  X  SPA  @0 Sistema nervioso central @5 44
N21       @1 273
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Format Inist (serveur)

NO : PASCAL 08-0417076 INIST
ET : Effect of External Cueing on Gait in Huntington's Disease
AU : DELVAL (Arnaud); KRYSTKOWIAK (Pierre); DELLIAUX (Marie); BLATT (Jean-Louis); DERAMBURE (Philippe); DESTEE (Alain); DEFEBVRE (Luc)
AF : Department of Neurology and Movement Disorders, EA 2683, IFR 114, Salengro Hospital, Lille Regional University Hospital/France (1 aut., 2 aut., 3 aut., 6 aut., 7 aut.); Department of Clinical Neurophysiology, EA 2683, IFR 114, Salengro Hospital, Lille Regional University Hospital/France (1 aut., 4 aut., 5 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 10; Pp. 1446-1452; Bibl. 19 ref.
LA : Anglais
EA : In Huntington's disease (HD) patients, gait is characterized by a timing disorder with marked intraindividual variability in temporal gait parameters (caused by the presence of both hyperkinetic and hypokinetic features). We sought to determine the influence of use of a metronome on gait parameters in patients simultaneously performing motor or cognitive tasks that required attentional resources. The objective is to evaluate the influence of rhythmic cues on gait interference during self-regulated walking and a dual task paradigm in HD. Fifteen HD patients and 15 paired controls were asked to walk and simultaneously perform another motor task (carrying a tray with four full glasses) or a cognitive task (counting backwards). We evaluated the effect of a metronome (set at 100% and 120% of the subject's self-determined cadence) in three different task conditions (gait alone, gait + motor task, gait + cognitive task). The use of auditory cues during free gait and dual tasks did not improve kinematic parameters in HD patients, in contrast to the situation for control subjects (improvement in gait speed and cadence but not stride length when the metronome was set at 120% in all conditions). HD patients have difficulty in synchronizing their footsteps with a metronome, mainly due to attentional deficits.
CC : 002B17; 002B17G
FD : Chorée de Huntington; Pathologie du système nerveux; Noyau gris central
FG : Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Maladie héréditaire; Pathologie du système nerveux central; Encéphale; Système nerveux central
ED : Huntington disease; Nervous system diseases; Basal ganglion
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Genetic disease; Central nervous system disease; Encephalon; Central nervous system
SD : Corea Huntington; Sistema nervioso patología; Núcleo basal
LO : INIST-20953.354000196364640140
ID : 08-0417076

Links to Exploration step

Pascal:08-0417076

Le document en format XML

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<fC03 i1="01" i2="X" l="ENG">
<s0>Huntington disease</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Corea Huntington</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Pathologie du système nerveux</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Nervous system diseases</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Sistema nervioso patología</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Noyau gris central</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Basal ganglion</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Núcleo basal</s0>
<s5>09</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Pathologie de l'encéphale</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Syndrome extrapyramidal</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Maladie héréditaire</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Genetic disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Enfermedad hereditaria</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Pathologie du système nerveux central</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>41</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Encéphale</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Encephalon</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Encéfalo</s0>
<s5>43</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE">
<s0>Système nerveux central</s0>
<s5>44</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG">
<s0>Central nervous system</s0>
<s5>44</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA">
<s0>Sistema nervioso central</s0>
<s5>44</s5>
</fC07>
<fN21>
<s1>273</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
<server>
<NO>PASCAL 08-0417076 INIST</NO>
<ET>Effect of External Cueing on Gait in Huntington's Disease</ET>
<AU>DELVAL (Arnaud); KRYSTKOWIAK (Pierre); DELLIAUX (Marie); BLATT (Jean-Louis); DERAMBURE (Philippe); DESTEE (Alain); DEFEBVRE (Luc)</AU>
<AF>Department of Neurology and Movement Disorders, EA 2683, IFR 114, Salengro Hospital, Lille Regional University Hospital/France (1 aut., 2 aut., 3 aut., 6 aut., 7 aut.); Department of Clinical Neurophysiology, EA 2683, IFR 114, Salengro Hospital, Lille Regional University Hospital/France (1 aut., 4 aut., 5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 10; Pp. 1446-1452; Bibl. 19 ref.</SO>
<LA>Anglais</LA>
<EA>In Huntington's disease (HD) patients, gait is characterized by a timing disorder with marked intraindividual variability in temporal gait parameters (caused by the presence of both hyperkinetic and hypokinetic features). We sought to determine the influence of use of a metronome on gait parameters in patients simultaneously performing motor or cognitive tasks that required attentional resources. The objective is to evaluate the influence of rhythmic cues on gait interference during self-regulated walking and a dual task paradigm in HD. Fifteen HD patients and 15 paired controls were asked to walk and simultaneously perform another motor task (carrying a tray with four full glasses) or a cognitive task (counting backwards). We evaluated the effect of a metronome (set at 100% and 120% of the subject's self-determined cadence) in three different task conditions (gait alone, gait + motor task, gait + cognitive task). The use of auditory cues during free gait and dual tasks did not improve kinematic parameters in HD patients, in contrast to the situation for control subjects (improvement in gait speed and cadence but not stride length when the metronome was set at 120% in all conditions). HD patients have difficulty in synchronizing their footsteps with a metronome, mainly due to attentional deficits.</EA>
<CC>002B17; 002B17G</CC>
<FD>Chorée de Huntington; Pathologie du système nerveux; Noyau gris central</FD>
<FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Maladie héréditaire; Pathologie du système nerveux central; Encéphale; Système nerveux central</FG>
<ED>Huntington disease; Nervous system diseases; Basal ganglion</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Genetic disease; Central nervous system disease; Encephalon; Central nervous system</EG>
<SD>Corea Huntington; Sistema nervioso patología; Núcleo basal</SD>
<LO>INIST-20953.354000196364640140</LO>
<ID>08-0417076</ID>
</server>
</inist>
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