Movement Disorders (revue)

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The Prodromal Phase of Sporadic Parkinson's Disease : Does It Exist and If So How Long Is It?

Identifieur interne : 001098 ( PascalFrancis/Corpus ); précédent : 001097; suivant : 001099

The Prodromal Phase of Sporadic Parkinson's Disease : Does It Exist and If So How Long Is It?

Auteurs : Christopher H. Hawkes

Source :

RBID : Pascal:08-0522174

Descripteurs français

English descriptors

Abstract

It is frequently assumed that idiopathic Parkinson's disease starts with several nonmotor symptoms and signs, but the evidence for this stage in the disease process is of variable quality. This review evaluates the more robust prospective or pathologically confirmed publications to establish whether there is a premotor period and if so what is its duration. The most informative studies are considered to be those concerned with olfaction, dysautonomia, and sleep disorder. Estimates for the duration of the prodromal phase vary from months to decades. It is concluded that there probably is an early phase in the disease where a variety of nonmotor features develop, but the sequence and time of onset of such features is not well established.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 23
A06       @2 13
A08 01  1  ENG  @1 The Prodromal Phase of Sporadic Parkinson's Disease : Does It Exist and If So How Long Is It?
A11 01  1    @1 HAWKES (Christopher H.)
A14 01      @1 Neuroscience Centre, Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry @2 London @3 GBR @Z 1 aut.
A20       @1 1799-1807
A21       @1 2008
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000184468160010
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 87 ref.
A47 01  1    @0 08-0522174
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 It is frequently assumed that idiopathic Parkinson's disease starts with several nonmotor symptoms and signs, but the evidence for this stage in the disease process is of variable quality. This review evaluates the more robust prospective or pathologically confirmed publications to establish whether there is a premotor period and if so what is its duration. The most informative studies are considered to be those concerned with olfaction, dysautonomia, and sleep disorder. Estimates for the duration of the prodromal phase vary from months to decades. It is concluded that there probably is an early phase in the disease where a variety of nonmotor features develop, but the sequence and time of onset of such features is not well established.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C03 01  X  FRE  @0 Maladie de Parkinson @2 NM @5 01
C03 01  X  ENG  @0 Parkinson disease @2 NM @5 01
C03 01  X  SPA  @0 Parkinson enfermedad @2 NM @5 01
C03 02  X  FRE  @0 Pathologie du système nerveux @5 02
C03 02  X  ENG  @0 Nervous system diseases @5 02
C03 02  X  SPA  @0 Sistema nervioso patología @5 02
C03 03  X  FRE  @0 Sporadique @5 09
C03 03  X  ENG  @0 Sporadic @5 09
C03 03  X  SPA  @0 Esporádico @5 09
C07 01  X  FRE  @0 Pathologie de l'encéphale @5 37
C07 01  X  ENG  @0 Cerebral disorder @5 37
C07 01  X  SPA  @0 Encéfalo patología @5 37
C07 02  X  FRE  @0 Syndrome extrapyramidal @5 38
C07 02  X  ENG  @0 Extrapyramidal syndrome @5 38
C07 02  X  SPA  @0 Extrapiramidal síndrome @5 38
C07 03  X  FRE  @0 Maladie dégénérative @5 39
C07 03  X  ENG  @0 Degenerative disease @5 39
C07 03  X  SPA  @0 Enfermedad degenerativa @5 39
C07 04  X  FRE  @0 Pathologie du système nerveux central @5 40
C07 04  X  ENG  @0 Central nervous system disease @5 40
C07 04  X  SPA  @0 Sistema nervosio central patología @5 40
N21       @1 343
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 08-0522174 INIST
ET : The Prodromal Phase of Sporadic Parkinson's Disease : Does It Exist and If So How Long Is It?
AU : HAWKES (Christopher H.)
AF : Neuroscience Centre, Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry/London/Royaume-Uni (1 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 13; Pp. 1799-1807; Bibl. 87 ref.
LA : Anglais
EA : It is frequently assumed that idiopathic Parkinson's disease starts with several nonmotor symptoms and signs, but the evidence for this stage in the disease process is of variable quality. This review evaluates the more robust prospective or pathologically confirmed publications to establish whether there is a premotor period and if so what is its duration. The most informative studies are considered to be those concerned with olfaction, dysautonomia, and sleep disorder. Estimates for the duration of the prodromal phase vary from months to decades. It is concluded that there probably is an early phase in the disease where a variety of nonmotor features develop, but the sequence and time of onset of such features is not well established.
CC : 002B17; 002B17G
FD : Maladie de Parkinson; Pathologie du système nerveux; Sporadique
FG : Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central
ED : Parkinson disease; Nervous system diseases; Sporadic
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD : Parkinson enfermedad; Sistema nervioso patología; Esporádico
LO : INIST-20953.354000184468160010
ID : 08-0522174

Links to Exploration step

Pascal:08-0522174

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