The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil
Identifieur interne : 001022 ( PascalFrancis/Corpus ); précédent : 001021; suivant : 001023The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil
Auteurs : Laura Silveira-Moriyama ; Margarete De Jesus Carvalho ; Regina Katzenschlager ; Aviva Petrie ; Ronald Ranvaud ; Egberto Reis Barbosa ; Andrew J. LeesSource :
- Movement disorders [ 0885-3185 ] ; 2008.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls), The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.
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Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 09-0058919 INIST |
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ET : | The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil |
AU : | SILVEIRA-MORIYAMA (Laura); CARVALHO (Margarete De Jesus); KATZENSCHLAGER (Regina); PETRIE (Aviva); RANVAUD (Ronald); REIS BARBOSA (Egberto); LEES (Andrew J.) |
AF : | Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology/London/Royaume-Uni (1 aut., 7 aut.); Neurology Department, São Paulo School of Medicine, University of São Paulo/São Paulo/Brésil (2 aut., 6 aut.); Department of Neurology, DonauspitallSozialmedizinisches Zentrum Ost/Vienna/Autriche (3 aut.); Biostatistics Unit, UCL Eastman Dental Institute/London/Royaume-Uni (4 aut.); Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sdo Paulo/São Paulo/Brésil (5 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 16; Pp. 2328-2334; Bibl. 40 ref. |
LA : | Anglais |
EA : | Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls), The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls. |
CC : | 002B17; 002B17G |
FD : | Maladie de Parkinson; Pathologie du système nerveux; Essai identification; Diagnostic; Brésil; Olfaction |
FG : | Amérique du Sud; Amérique; Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central |
ED : | Parkinson disease; Nervous system diseases; Identification test; Diagnosis; Brazil; Olfaction |
EG : | South America; America; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease |
SD : | Parkinson enfermedad; Sistema nervioso patología; Prueba identificación; Diagnóstico; Brasil; Olfación |
LO : | INIST-20953.354000196116650060 |
ID : | 09-0058919 |
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Pascal:09-0058919Le document en format XML
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<server><NO>PASCAL 09-0058919 INIST</NO>
<ET>The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil</ET>
<AU>SILVEIRA-MORIYAMA (Laura); CARVALHO (Margarete De Jesus); KATZENSCHLAGER (Regina); PETRIE (Aviva); RANVAUD (Ronald); REIS BARBOSA (Egberto); LEES (Andrew J.)</AU>
<AF>Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology/London/Royaume-Uni (1 aut., 7 aut.); Neurology Department, São Paulo School of Medicine, University of São Paulo/São Paulo/Brésil (2 aut., 6 aut.); Department of Neurology, DonauspitallSozialmedizinisches Zentrum Ost/Vienna/Autriche (3 aut.); Biostatistics Unit, UCL Eastman Dental Institute/London/Royaume-Uni (4 aut.); Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sdo Paulo/São Paulo/Brésil (5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 16; Pp. 2328-2334; Bibl. 40 ref.</SO>
<LA>Anglais</LA>
<EA>Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls), The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.</EA>
<CC>002B17; 002B17G</CC>
<FD>Maladie de Parkinson; Pathologie du système nerveux; Essai identification; Diagnostic; Brésil; Olfaction</FD>
<FG>Amérique du Sud; Amérique; Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central</FG>
<ED>Parkinson disease; Nervous system diseases; Identification test; Diagnosis; Brazil; Olfaction</ED>
<EG>South America; America; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease</EG>
<SD>Parkinson enfermedad; Sistema nervioso patología; Prueba identificación; Diagnóstico; Brasil; Olfación</SD>
<LO>INIST-20953.354000196116650060</LO>
<ID>09-0058919</ID>
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