Movement Disorders (revue)

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The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil

Identifieur interne : 001022 ( PascalFrancis/Corpus ); précédent : 001021; suivant : 001023

The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil

Auteurs : Laura Silveira-Moriyama ; Margarete De Jesus Carvalho ; Regina Katzenschlager ; Aviva Petrie ; Ronald Ranvaud ; Egberto Reis Barbosa ; Andrew J. Lees

Source :

RBID : Pascal:09-0058919

Descripteurs français

English descriptors

Abstract

Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls), The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A03   1    @0 Mov. disord.
A05       @2 23
A06       @2 16
A08 01  1  ENG  @1 The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil
A11 01  1    @1 SILVEIRA-MORIYAMA (Laura)
A11 02  1    @1 CARVALHO (Margarete De Jesus)
A11 03  1    @1 KATZENSCHLAGER (Regina)
A11 04  1    @1 PETRIE (Aviva)
A11 05  1    @1 RANVAUD (Ronald)
A11 06  1    @1 REIS BARBOSA (Egberto)
A11 07  1    @1 LEES (Andrew J.)
A14 01      @1 Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology @2 London @3 GBR @Z 1 aut. @Z 7 aut.
A14 02      @1 Neurology Department, São Paulo School of Medicine, University of São Paulo @2 São Paulo @3 BRA @Z 2 aut. @Z 6 aut.
A14 03      @1 Department of Neurology, DonauspitallSozialmedizinisches Zentrum Ost @2 Vienna @3 AUT @Z 3 aut.
A14 04      @1 Biostatistics Unit, UCL Eastman Dental Institute @2 London @3 GBR @Z 4 aut.
A14 05      @1 Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sdo Paulo @2 São Paulo @3 BRA @Z 5 aut.
A20       @1 2328-2334
A21       @1 2008
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000196116650060
A44       @0 0000 @1 © 2009 INIST-CNRS. All rights reserved.
A45       @0 40 ref.
A47 01  1    @0 09-0058919
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
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C01 01    ENG  @0 Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls), The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C03 01  X  FRE  @0 Maladie de Parkinson @2 NM @5 01
C03 01  X  ENG  @0 Parkinson disease @2 NM @5 01
C03 01  X  SPA  @0 Parkinson enfermedad @2 NM @5 01
C03 02  X  FRE  @0 Pathologie du système nerveux @5 02
C03 02  X  ENG  @0 Nervous system diseases @5 02
C03 02  X  SPA  @0 Sistema nervioso patología @5 02
C03 03  X  FRE  @0 Essai identification @5 09
C03 03  X  ENG  @0 Identification test @5 09
C03 03  X  SPA  @0 Prueba identificación @5 09
C03 04  X  FRE  @0 Diagnostic @5 10
C03 04  X  ENG  @0 Diagnosis @5 10
C03 04  X  SPA  @0 Diagnóstico @5 10
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C03 05  X  ENG  @0 Brazil @2 NG @5 11
C03 05  X  SPA  @0 Brasil @2 NG @5 11
C03 06  X  FRE  @0 Olfaction @5 12
C03 06  X  ENG  @0 Olfaction @5 12
C03 06  X  SPA  @0 Olfación @5 12
C07 01  X  FRE  @0 Amérique du Sud @2 NG
C07 01  X  ENG  @0 South America @2 NG
C07 01  X  SPA  @0 America del sur @2 NG
C07 02  X  FRE  @0 Amérique @2 NG
C07 02  X  ENG  @0 America @2 NG
C07 02  X  SPA  @0 America @2 NG
C07 03  X  FRE  @0 Pathologie de l'encéphale @5 37
C07 03  X  ENG  @0 Cerebral disorder @5 37
C07 03  X  SPA  @0 Encéfalo patología @5 37
C07 04  X  FRE  @0 Syndrome extrapyramidal @5 38
C07 04  X  ENG  @0 Extrapyramidal syndrome @5 38
C07 04  X  SPA  @0 Extrapiramidal síndrome @5 38
C07 05  X  FRE  @0 Maladie dégénérative @5 39
C07 05  X  ENG  @0 Degenerative disease @5 39
C07 05  X  SPA  @0 Enfermedad degenerativa @5 39
C07 06  X  FRE  @0 Pathologie du système nerveux central @5 40
C07 06  X  ENG  @0 Central nervous system disease @5 40
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Format Inist (serveur)

NO : PASCAL 09-0058919 INIST
ET : The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil
AU : SILVEIRA-MORIYAMA (Laura); CARVALHO (Margarete De Jesus); KATZENSCHLAGER (Regina); PETRIE (Aviva); RANVAUD (Ronald); REIS BARBOSA (Egberto); LEES (Andrew J.)
AF : Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology/London/Royaume-Uni (1 aut., 7 aut.); Neurology Department, São Paulo School of Medicine, University of São Paulo/São Paulo/Brésil (2 aut., 6 aut.); Department of Neurology, DonauspitallSozialmedizinisches Zentrum Ost/Vienna/Autriche (3 aut.); Biostatistics Unit, UCL Eastman Dental Institute/London/Royaume-Uni (4 aut.); Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sdo Paulo/São Paulo/Brésil (5 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 16; Pp. 2328-2334; Bibl. 40 ref.
LA : Anglais
EA : Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls), The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.
CC : 002B17; 002B17G
FD : Maladie de Parkinson; Pathologie du système nerveux; Essai identification; Diagnostic; Brésil; Olfaction
FG : Amérique du Sud; Amérique; Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central
ED : Parkinson disease; Nervous system diseases; Identification test; Diagnosis; Brazil; Olfaction
EG : South America; America; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD : Parkinson enfermedad; Sistema nervioso patología; Prueba identificación; Diagnóstico; Brasil; Olfación
LO : INIST-20953.354000196116650060
ID : 09-0058919

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Pascal:09-0058919

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<fC02 i1="02" i2="X">
<s0>002B17G</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE">
<s0>Maladie de Parkinson</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Parkinson disease</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Parkinson enfermedad</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Pathologie du système nerveux</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Nervous system diseases</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Sistema nervioso patología</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Essai identification</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Identification test</s0>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Prueba identificación</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Diagnostic</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Diagnosis</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Diagnóstico</s0>
<s5>10</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Brésil</s0>
<s2>NG</s2>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Brazil</s0>
<s2>NG</s2>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Brasil</s0>
<s2>NG</s2>
<s5>11</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Olfaction</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Olfaction</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Olfación</s0>
<s5>12</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Amérique du Sud</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>South America</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>America del sur</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Amérique</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>America</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>America</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Pathologie de l'encéphale</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Syndrome extrapyramidal</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Pathologie du système nerveux central</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fN21>
<s1>040</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
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<server>
<NO>PASCAL 09-0058919 INIST</NO>
<ET>The Use of Smell Identification Tests in the Diagnosis of Parkinson's Disease in Brazil</ET>
<AU>SILVEIRA-MORIYAMA (Laura); CARVALHO (Margarete De Jesus); KATZENSCHLAGER (Regina); PETRIE (Aviva); RANVAUD (Ronald); REIS BARBOSA (Egberto); LEES (Andrew J.)</AU>
<AF>Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology/London/Royaume-Uni (1 aut., 7 aut.); Neurology Department, São Paulo School of Medicine, University of São Paulo/São Paulo/Brésil (2 aut., 6 aut.); Department of Neurology, DonauspitallSozialmedizinisches Zentrum Ost/Vienna/Autriche (3 aut.); Biostatistics Unit, UCL Eastman Dental Institute/London/Royaume-Uni (4 aut.); Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sdo Paulo/São Paulo/Brésil (5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2008; Vol. 23; No. 16; Pp. 2328-2334; Bibl. 40 ref.</SO>
<LA>Anglais</LA>
<EA>Smell identification tests may be of routine clinical value in the differential diagnosis of PD but are subject to cultural variation and have not been systematically evaluated in the Brazilian population. We have applied culturally adapted translations of the University of Pennsylvania 40-item smell identification test (UPSIT-40) and the 16-item identification test from Sniffin' Sticks (SS-16) to nondemented Brazilian PD patients and controls. Pearson's correlation coefficient between the test scores was 0.76 (95% CI 0.70-0.81, n = 204, P < 0.001). To calculate reliability measures for each test we used the diagnosis (either PD or control) as outcome variable for separate logistic regression analyses using the score in the UPSIT-40 or the SS-16 as a covariate. The SS-16 specificity was 89.0% with a sensitivity of 81.1% (106 PD and 118 controls), The UPSIT-40 specificity was 83.5% and its sensitivity 82.1% (95 PD and 109 controls). Regression curves were used to associate an individual's smell test score with the probability of belonging to the PD, as opposed to the control group. Our data provide support for the use of the UPSIT-40 and SS-16 to help distinguish early PD from controls.</EA>
<CC>002B17; 002B17G</CC>
<FD>Maladie de Parkinson; Pathologie du système nerveux; Essai identification; Diagnostic; Brésil; Olfaction</FD>
<FG>Amérique du Sud; Amérique; Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central</FG>
<ED>Parkinson disease; Nervous system diseases; Identification test; Diagnosis; Brazil; Olfaction</ED>
<EG>South America; America; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease</EG>
<SD>Parkinson enfermedad; Sistema nervioso patología; Prueba identificación; Diagnóstico; Brasil; Olfación</SD>
<LO>INIST-20953.354000196116650060</LO>
<ID>09-0058919</ID>
</server>
</inist>
</record>

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