Movement Disorders (revue)

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Validation of the Freezing of Gait Questionnaire in Patients with Parkinson's Disease

Identifieur interne : 000F22 ( PascalFrancis/Corpus ); précédent : 000F21; suivant : 000F23

Validation of the Freezing of Gait Questionnaire in Patients with Parkinson's Disease

Auteurs : Nir Giladi ; Joseph Tal ; Tali Azulay ; Oliver Rascol ; David J. Brooks ; Eldad Melamed ; Wolfgang Oertel ; Werner H. Poewe ; Fabrizio Stocchi ; Eduardo Tolosa

Source :

RBID : Pascal:09-0218140

Descripteurs français

English descriptors

Abstract

To revalidate the Freezing of Gait Questionnaire (FOG-Q), patients with Parkinson's disease (PD) were randomly assigned to receive rasagiline (1 mg/day) (n = 150), entacapone (200 mg with each dose of levodopa) (n = 150), or placebo (n = 154). Patients were assessed at baseline and after 10 weeks using the FOG-Q, Unified Parkinson's Disease Rating Scale (UPDRS), Beck Depression Inventory (BDI), and Parkinson's Disease Questionnaire (PDQ-39). FOG-Q dimensionality, test-retest reliability, and internal reliability were examined. Convergent and divergent validities were assessed by correlating FOG-Q with UPDRS, BDI, and PDQ-39. Comparisons between FOG-Q item 3 and UPDRS item 14 were also made. Principal component analysis indicated that FOG-Q measures a single dimension. Test-retest reliability and internal reliability of FOG-Q score was high. FOG-Q was best correlated to items of the UPDRS relating to walking, general motor issues, and mobility. Correlations between baseline and endpoint suggested that FOG-Q item 3 is at least as reliable as UPDRS item 14. At baseline, 85.9% of patients were identified as "Freezers" using FOG-Q item 3 (≥1) and 44.1% using UPDRS item 14 (≥1) (P < 0.001). FOG-Q was a reliable tool for the assessment of treatment intervention. FOG-Q item 3 was effective as a screening question for the presence of FOG.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 24
A06       @2 5
A08 01  1  ENG  @1 Validation of the Freezing of Gait Questionnaire in Patients with Parkinson's Disease
A11 01  1    @1 GILADI (Nir)
A11 02  1    @1 TAL (Joseph)
A11 03  1    @1 AZULAY (Tali)
A11 04  1    @1 RASCOL (Oliver)
A11 05  1    @1 BROOKS (David J.)
A11 06  1    @1 MELAMED (Eldad)
A11 07  1    @1 OERTEL (Wolfgang)
A11 08  1    @1 POEWE (Werner H.)
A11 09  1    @1 STOCCHI (Fabrizio)
A11 10  1    @1 TOLOSA (Eduardo)
A14 01      @1 Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University @2 Tel-Aviv @3 ISR @Z 1 aut.
A14 02      @1 TechnoStat Ltd @2 Hod Hasharon @3 ISR @Z 2 aut. @Z 3 aut.
A14 03      @1 Service de Pharmacologie Medicale et Clinique, Faculté de Médecine @2 Toulouse @3 FRA @Z 4 aut.
A14 04      @1 Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital @2 London @3 GBR @Z 5 aut.
A14 05      @1 Department of Neurology, Rabin Medical Centre, Sackler School of Medicine, Tel-Aviv University @2 Tel-Aviv @3 ISR @Z 6 aut.
A14 06      @1 Centre of Nervous Diseases, Philipps-University of Marburg @2 Marburg @3 DEU @Z 7 aut.
A14 07      @1 Department of Neurology, University of Innsbruck @2 Innsbruck @3 AUT @Z 8 aut.
A14 08      @1 Department of Neuroscience and Neuromed, University La Sapienza @2 Rome @3 ITA @Z 9 aut.
A14 09      @1 Neurology Department, Hospital Clinic @2 Barcelona @3 ESP @Z 10 aut.
A20       @1 655-661
A21       @1 2009
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000186090170030
A44       @0 0000 @1 © 2009 INIST-CNRS. All rights reserved.
A45       @0 24 ref.
A47 01  1    @0 09-0218140
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 To revalidate the Freezing of Gait Questionnaire (FOG-Q), patients with Parkinson's disease (PD) were randomly assigned to receive rasagiline (1 mg/day) (n = 150), entacapone (200 mg with each dose of levodopa) (n = 150), or placebo (n = 154). Patients were assessed at baseline and after 10 weeks using the FOG-Q, Unified Parkinson's Disease Rating Scale (UPDRS), Beck Depression Inventory (BDI), and Parkinson's Disease Questionnaire (PDQ-39). FOG-Q dimensionality, test-retest reliability, and internal reliability were examined. Convergent and divergent validities were assessed by correlating FOG-Q with UPDRS, BDI, and PDQ-39. Comparisons between FOG-Q item 3 and UPDRS item 14 were also made. Principal component analysis indicated that FOG-Q measures a single dimension. Test-retest reliability and internal reliability of FOG-Q score was high. FOG-Q was best correlated to items of the UPDRS relating to walking, general motor issues, and mobility. Correlations between baseline and endpoint suggested that FOG-Q item 3 is at least as reliable as UPDRS item 14. At baseline, 85.9% of patients were identified as "Freezers" using FOG-Q item 3 (≥1) and 44.1% using UPDRS item 14 (≥1) (P < 0.001). FOG-Q was a reliable tool for the assessment of treatment intervention. FOG-Q item 3 was effective as a screening question for the presence of FOG.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C03 01  X  FRE  @0 Maladie de Parkinson @2 NM @5 01
C03 01  X  ENG  @0 Parkinson disease @2 NM @5 01
C03 01  X  SPA  @0 Parkinson enfermedad @2 NM @5 01
C03 02  X  FRE  @0 Pathologie du système nerveux @5 02
C03 02  X  ENG  @0 Nervous system diseases @5 02
C03 02  X  SPA  @0 Sistema nervioso patología @5 02
C03 03  X  FRE  @0 Validation @5 09
C03 03  X  ENG  @0 Validation @5 09
C03 03  X  SPA  @0 Validación @5 09
C03 04  X  FRE  @0 Congélation @5 10
C03 04  X  ENG  @0 Freezing @5 10
C03 04  X  SPA  @0 Congelación @5 10
C03 05  X  FRE  @0 Questionnaire @5 11
C03 05  X  ENG  @0 Questionnaire @5 11
C03 05  X  SPA  @0 Cuestionario @5 11
C03 06  X  FRE  @0 Homme @5 12
C03 06  X  ENG  @0 Human @5 12
C03 06  X  SPA  @0 Hombre @5 12
C03 07  X  FRE  @0 Rasagiline @2 NK @2 FR @5 13
C03 07  X  ENG  @0 Rasagiline @2 NK @2 FR @5 13
C03 07  X  SPA  @0 Rasagilina @2 NK @2 FR @5 13
C07 01  X  FRE  @0 Pathologie de l'encéphale @5 37
C07 01  X  ENG  @0 Cerebral disorder @5 37
C07 01  X  SPA  @0 Encéfalo patología @5 37
C07 02  X  FRE  @0 Syndrome extrapyramidal @5 38
C07 02  X  ENG  @0 Extrapyramidal syndrome @5 38
C07 02  X  SPA  @0 Extrapiramidal síndrome @5 38
C07 03  X  FRE  @0 Maladie dégénérative @5 39
C07 03  X  ENG  @0 Degenerative disease @5 39
C07 03  X  SPA  @0 Enfermedad degenerativa @5 39
C07 04  X  FRE  @0 Pathologie du système nerveux central @5 40
C07 04  X  ENG  @0 Central nervous system disease @5 40
C07 04  X  SPA  @0 Sistema nervosio central patología @5 40
N21       @1 159
N44 01      @1 OTO
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Format Inist (serveur)

NO : PASCAL 09-0218140 INIST
ET : Validation of the Freezing of Gait Questionnaire in Patients with Parkinson's Disease
AU : GILADI (Nir); TAL (Joseph); AZULAY (Tali); RASCOL (Oliver); BROOKS (David J.); MELAMED (Eldad); OERTEL (Wolfgang); POEWE (Werner H.); STOCCHI (Fabrizio); TOLOSA (Eduardo)
AF : Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University/Tel-Aviv/Israël (1 aut.); TechnoStat Ltd/Hod Hasharon/Israël (2 aut., 3 aut.); Service de Pharmacologie Medicale et Clinique, Faculté de Médecine/Toulouse/France (4 aut.); Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital/London/Royaume-Uni (5 aut.); Department of Neurology, Rabin Medical Centre, Sackler School of Medicine, Tel-Aviv University/Tel-Aviv/Israël (6 aut.); Centre of Nervous Diseases, Philipps-University of Marburg/Marburg/Allemagne (7 aut.); Department of Neurology, University of Innsbruck/Innsbruck/Autriche (8 aut.); Department of Neuroscience and Neuromed, University La Sapienza/Rome/Italie (9 aut.); Neurology Department, Hospital Clinic/Barcelona/Espagne (10 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2009; Vol. 24; No. 5; Pp. 655-661; Bibl. 24 ref.
LA : Anglais
EA : To revalidate the Freezing of Gait Questionnaire (FOG-Q), patients with Parkinson's disease (PD) were randomly assigned to receive rasagiline (1 mg/day) (n = 150), entacapone (200 mg with each dose of levodopa) (n = 150), or placebo (n = 154). Patients were assessed at baseline and after 10 weeks using the FOG-Q, Unified Parkinson's Disease Rating Scale (UPDRS), Beck Depression Inventory (BDI), and Parkinson's Disease Questionnaire (PDQ-39). FOG-Q dimensionality, test-retest reliability, and internal reliability were examined. Convergent and divergent validities were assessed by correlating FOG-Q with UPDRS, BDI, and PDQ-39. Comparisons between FOG-Q item 3 and UPDRS item 14 were also made. Principal component analysis indicated that FOG-Q measures a single dimension. Test-retest reliability and internal reliability of FOG-Q score was high. FOG-Q was best correlated to items of the UPDRS relating to walking, general motor issues, and mobility. Correlations between baseline and endpoint suggested that FOG-Q item 3 is at least as reliable as UPDRS item 14. At baseline, 85.9% of patients were identified as "Freezers" using FOG-Q item 3 (≥1) and 44.1% using UPDRS item 14 (≥1) (P < 0.001). FOG-Q was a reliable tool for the assessment of treatment intervention. FOG-Q item 3 was effective as a screening question for the presence of FOG.
CC : 002B17; 002B17G
FD : Maladie de Parkinson; Pathologie du système nerveux; Validation; Congélation; Questionnaire; Homme; Rasagiline
FG : Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central
ED : Parkinson disease; Nervous system diseases; Validation; Freezing; Questionnaire; Human; Rasagiline
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD : Parkinson enfermedad; Sistema nervioso patología; Validación; Congelación; Cuestionario; Hombre; Rasagilina
LO : INIST-20953.354000186090170030
ID : 09-0218140

Links to Exploration step

Pascal:09-0218140

Le document en format XML

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<div type="abstract" xml:lang="en">To revalidate the Freezing of Gait Questionnaire (FOG-Q), patients with Parkinson's disease (PD) were randomly assigned to receive rasagiline (1 mg/day) (n = 150), entacapone (200 mg with each dose of levodopa) (n = 150), or placebo (n = 154). Patients were assessed at baseline and after 10 weeks using the FOG-Q, Unified Parkinson's Disease Rating Scale (UPDRS), Beck Depression Inventory (BDI), and Parkinson's Disease Questionnaire (PDQ-39). FOG-Q dimensionality, test-retest reliability, and internal reliability were examined. Convergent and divergent validities were assessed by correlating FOG-Q with UPDRS, BDI, and PDQ-39. Comparisons between FOG-Q item 3 and UPDRS item 14 were also made. Principal component analysis indicated that FOG-Q measures a single dimension. Test-retest reliability and internal reliability of FOG-Q score was high. FOG-Q was best correlated to items of the UPDRS relating to walking, general motor issues, and mobility. Correlations between baseline and endpoint suggested that FOG-Q item 3 is at least as reliable as UPDRS item 14. At baseline, 85.9% of patients were identified as "Freezers" using FOG-Q item 3 (≥1) and 44.1% using UPDRS item 14 (≥1) (P < 0.001). FOG-Q was a reliable tool for the assessment of treatment intervention. FOG-Q item 3 was effective as a screening question for the presence of FOG.</div>
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<NO>PASCAL 09-0218140 INIST</NO>
<ET>Validation of the Freezing of Gait Questionnaire in Patients with Parkinson's Disease</ET>
<AU>GILADI (Nir); TAL (Joseph); AZULAY (Tali); RASCOL (Oliver); BROOKS (David J.); MELAMED (Eldad); OERTEL (Wolfgang); POEWE (Werner H.); STOCCHI (Fabrizio); TOLOSA (Eduardo)</AU>
<AF>Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University/Tel-Aviv/Israël (1 aut.); TechnoStat Ltd/Hod Hasharon/Israël (2 aut., 3 aut.); Service de Pharmacologie Medicale et Clinique, Faculté de Médecine/Toulouse/France (4 aut.); Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital/London/Royaume-Uni (5 aut.); Department of Neurology, Rabin Medical Centre, Sackler School of Medicine, Tel-Aviv University/Tel-Aviv/Israël (6 aut.); Centre of Nervous Diseases, Philipps-University of Marburg/Marburg/Allemagne (7 aut.); Department of Neurology, University of Innsbruck/Innsbruck/Autriche (8 aut.); Department of Neuroscience and Neuromed, University La Sapienza/Rome/Italie (9 aut.); Neurology Department, Hospital Clinic/Barcelona/Espagne (10 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2009; Vol. 24; No. 5; Pp. 655-661; Bibl. 24 ref.</SO>
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<EA>To revalidate the Freezing of Gait Questionnaire (FOG-Q), patients with Parkinson's disease (PD) were randomly assigned to receive rasagiline (1 mg/day) (n = 150), entacapone (200 mg with each dose of levodopa) (n = 150), or placebo (n = 154). Patients were assessed at baseline and after 10 weeks using the FOG-Q, Unified Parkinson's Disease Rating Scale (UPDRS), Beck Depression Inventory (BDI), and Parkinson's Disease Questionnaire (PDQ-39). FOG-Q dimensionality, test-retest reliability, and internal reliability were examined. Convergent and divergent validities were assessed by correlating FOG-Q with UPDRS, BDI, and PDQ-39. Comparisons between FOG-Q item 3 and UPDRS item 14 were also made. Principal component analysis indicated that FOG-Q measures a single dimension. Test-retest reliability and internal reliability of FOG-Q score was high. FOG-Q was best correlated to items of the UPDRS relating to walking, general motor issues, and mobility. Correlations between baseline and endpoint suggested that FOG-Q item 3 is at least as reliable as UPDRS item 14. At baseline, 85.9% of patients were identified as "Freezers" using FOG-Q item 3 (≥1) and 44.1% using UPDRS item 14 (≥1) (P < 0.001). FOG-Q was a reliable tool for the assessment of treatment intervention. FOG-Q item 3 was effective as a screening question for the presence of FOG.</EA>
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