MovDisordV3, PascalFrancis, Corpus, bibRecord, 000C68

Non-Therapeutic Risk Factors for Onset of Tardive Dyskinesia in Schizophrenia: A Meta-Analysis

Identifieur interne : 000C68 ( PascalFrancis/Corpus ); précédent : 000C67; suivant : 000C69

Non-Therapeutic Risk Factors for Onset of Tardive Dyskinesia in Schizophrenia: A Meta-Analysis

Auteurs : Diederik E. Tenback ; Peter N. Van Harten ; Jim Van Os

Source :

Movement disorders [ 0885-3185 ] ; 2009.

RBID : Pascal:10-0071251

Descripteurs français

Pascal (Inist)
- Dyskinésie, Schizophrénie, Syndrome extrapyramidal, Acathisie, Pathologie du système nerveux, Traitement, Facteur risque.

English descriptors

KwdEn :
- Akathisia, Dyskinesia, Extrapyramidal syndrome, Nervous system diseases, Risk factor, Schizophrenia, Treatment.

Abstract

A meta-analysis of prospective studies with schizophrenia patients was conducted to examine whether the evidence exists for risk factors for the emergence of Tardive Dyskinesia (TD) in schizophrenia. A computer assisted Medline/ PubMed and Embase search was conducted in January 2008 for the years 1985-2007. Selected were truly prospective studies of incident cases of TD in a population with at least 80% patients with schizophrenia. Measures of relative risk were collected from the individual studies, either directly or by calculating the relative risk from the cox- or logistic regression coefficient provided in the article. Hazard Ratio's and Odds Ratio's were pooled using fixed and random effect models in case of multiple studies using the same measure of risk and outcome. Only eight studies satisfied the inclusion criteria reporting on 25 different single estimate risk factors. Of 25 risk factors, six concerned replicated estimates suitable for meta-analysis. Of these, non-white ethnic group and early extrapyramidal symptoms qualified as risk factors for the emergence of TD in schizophrenia. The association with older age was suggestive but inconclusive. Despite many reported risk factors for TD in schizophrenia, little conclusive evidence exists to corroborate this. However, the fact that early EPS predicts onset of TD has important clinical and research implications.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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C07	`02`	`X`	`FRE`	`@0 Trouble neurologique @5 39`
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Format Inist (serveur)

NO :	PASCAL 10-0071251 INIST
ET :	Non-Therapeutic Risk Factors for Onset of Tardive Dyskinesia in Schizophrenia: A Meta-Analysis
AU :	TENBACK (Diederik E.); VAN HARTEN (Peter N.); VAN OS (Jim)
AF :	Psychiatric Center Symfora Group, DB/Amersfoort/Pays-Bas (1 aut., 2 aut.); Department of Psychiatry, University Medical Center Utrecht/Utrecht/Pays-Bas (1 aut.); University Medical Center Groningen/Groningen/Pays-Bas (2 aut.); Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University/Maastricht/Pays-Bas (3 aut.); Division of Psychological Medicine, Institute of Psychiatry/London/Royaume-Uni (3 aut.)
DT :	Publication en série; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2009; Vol. 24; No. 16; Pp. 2309-2315; Bibl. 51 ref.
LA :	Anglais
EA :	A meta-analysis of prospective studies with schizophrenia patients was conducted to examine whether the evidence exists for risk factors for the emergence of Tardive Dyskinesia (TD) in schizophrenia. A computer assisted Medline/ PubMed and Embase search was conducted in January 2008 for the years 1985-2007. Selected were truly prospective studies of incident cases of TD in a population with at least 80% patients with schizophrenia. Measures of relative risk were collected from the individual studies, either directly or by calculating the relative risk from the cox- or logistic regression coefficient provided in the article. Hazard Ratio's and Odds Ratio's were pooled using fixed and random effect models in case of multiple studies using the same measure of risk and outcome. Only eight studies satisfied the inclusion criteria reporting on 25 different single estimate risk factors. Of 25 risk factors, six concerned replicated estimates suitable for meta-analysis. Of these, non-white ethnic group and early extrapyramidal symptoms qualified as risk factors for the emergence of TD in schizophrenia. The association with older age was suggestive but inconclusive. Despite many reported risk factors for TD in schizophrenia, little conclusive evidence exists to corroborate this. However, the fact that early EPS predicts onset of TD has important clinical and research implications.
CC :	002B17; 002B02U01
FD :	Dyskinésie; Schizophrénie; Syndrome extrapyramidal; Acathisie; Pathologie du système nerveux; Traitement; Facteur risque
FG :	Mouvement involontaire; Trouble neurologique; Psychose; Pathologie de l'encéphale; Pathologie du système nerveux central
ED :	Dyskinesia; Schizophrenia; Extrapyramidal syndrome; Akathisia; Nervous system diseases; Treatment; Risk factor
EG :	Involuntary movement; Neurological disorder; Psychosis; Cerebral disorder; Central nervous system disease
SD :	Disquinesia; Esquizofrenia; Extrapiramidal síndrome; Acatisia; Sistema nervioso patología; Tratamiento; Factor riesgo
LO :	INIST-20953.354000190005540010
ID :	10-0071251

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Pascal:10-0071251

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<front><div type="abstract" xml:lang="en">A meta-analysis of prospective studies with schizophrenia patients was conducted to examine whether the evidence exists for risk factors for the emergence of Tardive Dyskinesia (TD) in schizophrenia. A computer assisted Medline/ PubMed and Embase search was conducted in January 2008 for the years 1985-2007. Selected were truly prospective studies of incident cases of TD in a population with at least 80% patients with schizophrenia. Measures of relative risk were collected from the individual studies, either directly or by calculating the relative risk from the cox- or logistic regression coefficient provided in the article. Hazard Ratio's and Odds Ratio's were pooled using fixed and random effect models in case of multiple studies using the same measure of risk and outcome. Only eight studies satisfied the inclusion criteria reporting on 25 different single estimate risk factors. Of 25 risk factors, six concerned replicated estimates suitable for meta-analysis. Of these, non-white ethnic group and early extrapyramidal symptoms qualified as risk factors for the emergence of TD in schizophrenia. The association with older age was suggestive but inconclusive. Despite many reported risk factors for TD in schizophrenia, little conclusive evidence exists to corroborate this. However, the fact that early EPS predicts onset of TD has important clinical and research implications.</div>
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<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Factor riesgo</s0>
<s5>10</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Mouvement involontaire</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Involuntary movement</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Movimiento involuntario</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Trouble neurologique</s0>
<s5>39</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Neurological disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Trastorno neurológico</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Psychose</s0>
<s5>40</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Psychosis</s0>
<s5>40</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Psicosis</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Pathologie de l'encéphale</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Pathologie du   système nerveux central</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>42</s5>
</fC07>
<fN21><s1>046</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 10-0071251 INIST</NO>
<ET>Non-Therapeutic Risk Factors for Onset of Tardive Dyskinesia in Schizophrenia: A Meta-Analysis</ET>
<AU>TENBACK (Diederik E.); VAN HARTEN (Peter N.); VAN OS (Jim)</AU>
<AF>Psychiatric Center Symfora Group, DB/Amersfoort/Pays-Bas (1 aut., 2 aut.); Department of Psychiatry, University Medical Center Utrecht/Utrecht/Pays-Bas (1 aut.); University Medical Center Groningen/Groningen/Pays-Bas (2 aut.); Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University/Maastricht/Pays-Bas (3 aut.); Division of Psychological Medicine, Institute of Psychiatry/London/Royaume-Uni (3 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2009; Vol. 24; No. 16; Pp. 2309-2315; Bibl. 51 ref.</SO>
<LA>Anglais</LA>
<EA>A meta-analysis of prospective studies with schizophrenia patients was conducted to examine whether the evidence exists for risk factors for the emergence of Tardive Dyskinesia (TD) in schizophrenia. A computer assisted Medline/ PubMed and Embase search was conducted in January 2008 for the years 1985-2007. Selected were truly prospective studies of incident cases of TD in a population with at least 80% patients with schizophrenia. Measures of relative risk were collected from the individual studies, either directly or by calculating the relative risk from the cox- or logistic regression coefficient provided in the article. Hazard Ratio's and Odds Ratio's were pooled using fixed and random effect models in case of multiple studies using the same measure of risk and outcome. Only eight studies satisfied the inclusion criteria reporting on 25 different single estimate risk factors. Of 25 risk factors, six concerned replicated estimates suitable for meta-analysis. Of these, non-white ethnic group and early extrapyramidal symptoms qualified as risk factors for the emergence of TD in schizophrenia. The association with older age was suggestive but inconclusive. Despite many reported risk factors for TD in schizophrenia, little conclusive evidence exists to corroborate this. However, the fact that early EPS predicts onset of TD has important clinical and research implications.</EA>
<CC>002B17; 002B02U01</CC>
<FD>Dyskinésie; Schizophrénie; Syndrome extrapyramidal; Acathisie; Pathologie du   système nerveux; Traitement; Facteur risque</FD>
<FG>Mouvement involontaire; Trouble neurologique; Psychose; Pathologie de l'encéphale; Pathologie du   système nerveux central</FG>
<ED>Dyskinesia; Schizophrenia; Extrapyramidal syndrome; Akathisia; Nervous system diseases; Treatment; Risk factor</ED>
<EG>Involuntary movement; Neurological disorder; Psychosis; Cerebral disorder; Central nervous system disease</EG>
<SD>Disquinesia; Esquizofrenia; Extrapiramidal síndrome; Acatisia; Sistema nervioso patología; Tratamiento; Factor riesgo</SD>
<LO>INIST-20953.354000190005540010</LO>
<ID>10-0071251</ID>
</server>
</inist>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Non-Therapeutic Risk Factors for Onset of Tardive Dyskinesia in Schizophrenia: A Meta-Analysis

Non-Therapeutic Risk Factors for Onset of Tardive Dyskinesia in Schizophrenia: A Meta-Analysis

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