MovDisordV3, PascalFrancis, Corpus, bibRecord, 000B35

Gray Matter Correlations of Cognition in Incident Parkinson's Disease

Identifieur interne : 000B35 ( PascalFrancis/Corpus ); précédent : 000B34; suivant : 000B36

Gray Matter Correlations of Cognition in Incident Parkinson's Disease

Auteurs : Turi O. Dalaker ; Robert Zivadinov ; Jan P. Larsen ; Mona K. Beyer ; Jennifer L. Cox ; Guido Alves ; Kolbjorn Bronnick ; Ole-Bjorn Tysnes ; Ronald Antulov ; Michael G. Dwyer ; Dag Aarsland

Source :

Movement disorders [ 0885-3185 ] ; 2010.

RBID : Pascal:10-0233228

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Atrophie, Déficit cognitif léger, Trouble cognitif, Pathologie du système nerveux, Cognition, Imagerie RMN, Voxel, Morphométrie, Encéphale.

English descriptors

KwdEn :
- Atrophy, Cognition, Cognitive disorder, Encephalon, Morphometry, Nervous system diseases, Nuclear magnetic resonance imaging, Parkinson disease, Voxel, mild cognitive impairment.

Abstract

We aimed to investigate whether mild cognitive impairment (MCI) in Parkinson's disease (PD) is characterized by region-specific gray matter (GM) atrophy and to explore correlations between GM and cognition in PD. Magnetic resonance images of 42 newly diagnosed PD patients (of which 11 had MCI) and 37 normal controls were analyzed using voxel-based morphometry. Analyses comparing groups showed no regional atrophy, and in patients there were no significant correlations between cognitive domain test performance and GM loss. In conclusion, GM atrophy does not seem to be a major feature of cognitive dysfunction in incident PD.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A11	`01`	`1`		`@1 DALAKER (Turi O.)`
A11	`02`	`1`		`@1 ZIVADINOV (Robert)`
A11	`03`	`1`		`@1 LARSEN (Jan P.)`
A11	`04`	`1`		`@1 BEYER (Mona K.)`
A11	`05`	`1`		`@1 COX (Jennifer L.)`
A11	`06`	`1`		`@1 ALVES (Guido)`
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A14	`01`			`@1 Department of Neurology, Buffalo Neuroimaging Analysis Center, State University of New York at Buffalo @2 Buffalo, New York @3 USA @Z 1 aut. @Z 2 aut. @Z 9 aut. @Z 10 aut.`
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C01	`01`		`ENG`	@0 We aimed to investigate whether mild cognitive impairment (MCI) in Parkinson's disease (PD) is characterized by region-specific gray matter (GM) atrophy and to explore correlations between GM and cognition in PD. Magnetic resonance images of 42 newly diagnosed PD patients (of which 11 had MCI) and 37 normal controls were analyzed using voxel-based morphometry. Analyses comparing groups showed no regional atrophy, and in patients there were no significant correlations between cognitive domain test performance and GM loss. In conclusion, GM atrophy does not seem to be a major feature of cognitive dysfunction in incident PD.
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C03	`02`	`X`	`ENG`	`@0 Atrophy @5 02`
C03	`02`	`X`	`SPA`	`@0 Atrofia @5 02`
C03	`03`	`X`	`FRE`	`@0 Déficit cognitif léger @2 NM @5 03`
C03	`03`	`X`	`ENG`	`@0 mild cognitive impairment @2 NM @5 03`
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C03	`05`	`X`	`FRE`	`@0 Pathologie du système nerveux @5 05`
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C03	`05`	`X`	`SPA`	`@0 Sistema nervioso patología @5 05`
C03	`06`	`X`	`FRE`	`@0 Cognition @5 09`
C03	`06`	`X`	`ENG`	`@0 Cognition @5 09`
C03	`06`	`X`	`SPA`	`@0 Cognición @5 09`
C03	`07`	`X`	`FRE`	`@0 Imagerie RMN @5 10`
C03	`07`	`X`	`ENG`	`@0 Nuclear magnetic resonance imaging @5 10`
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C03	`08`	`X`	`SPA`	`@0 Voxel @5 11`
C03	`09`	`X`	`FRE`	`@0 Morphométrie @5 12`
C03	`09`	`X`	`ENG`	`@0 Morphometry @5 12`
C03	`09`	`X`	`SPA`	`@0 Morfometría @5 12`
C03	`10`	`X`	`FRE`	`@0 Encéphale @5 13`
C03	`10`	`X`	`ENG`	`@0 Encephalon @5 13`
C03	`10`	`X`	`SPA`	`@0 Encéfalo @5 13`
C07	`01`	`X`	`FRE`	`@0 Pathologie de l'encéphale @5 37`
C07	`01`	`X`	`ENG`	`@0 Cerebral disorder @5 37`
C07	`01`	`X`	`SPA`	`@0 Encéfalo patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Syndrome extrapyramidal @5 38`
C07	`02`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 38`
C07	`02`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 38`
C07	`03`	`X`	`FRE`	`@0 Maladie dégénérative @5 39`
C07	`03`	`X`	`ENG`	`@0 Degenerative disease @5 39`
C07	`03`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 39`
C07	`04`	`X`	`FRE`	`@0 Pathologie du système nerveux central @5 40`
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C07	`05`	`X`	`ENG`	`@0 Central nervous system @5 42`
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N21				`@1 158`
N44	`01`			`@1 OTO`
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Format Inist (serveur)

NO :	PASCAL 10-0233228 INIST
ET :	Gray Matter Correlations of Cognition in Incident Parkinson's Disease
AU :	DALAKER (Turi O.); ZIVADINOV (Robert); LARSEN (Jan P.); BEYER (Mona K.); COX (Jennifer L.); ALVES (Guido); BRONNICK (Kolbjorn); TYSNES (Ole-Bjorn); ANTULOV (Ronald); DWYER (Michael G.); AARSLAND (Dag)
AF :	Department of Neurology, Buffalo Neuroimaging Analysis Center, State University of New York at Buffalo/Buffalo, New York/Etats-Unis (1 aut., 2 aut., 9 aut., 10 aut.); Department of Radiology, Stavanger University Hospital/Stavanger/Norvège (1 aut., 4 aut.); The Norwegian Centre for Movement Disorders, Stavanger University Hospital/Stavanger/Norvège (1 aut., 3 aut., 4 aut., 6 aut., 7 aut., 11 aut.); Department of Neurology, The Jacobs Neurological Institute, State University of New York at Buffalo/Buffalo, New York/Etats-Unis (2 aut., 5 aut.); Department of Neurology, Stavanger University Hospital/Stavanger/Norvège (3 aut., 6 aut.); Institute of Clinical Medicine, University of Bergen/Bergen/Norvège (3 aut., 8 aut., 11 aut.); Department of Neurology, Haukeland University Hospital/Bergen/Norvège (8 aut.); Department of Radiology, Clinical Hospital Centre Rijeka/Rijeka/Croatie (9 aut.)
DT :	Publication en série; Courte communication, note brève; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 5; Pp. 629-633; Bibl. 17 ref.
LA :	Anglais
EA :	We aimed to investigate whether mild cognitive impairment (MCI) in Parkinson's disease (PD) is characterized by region-specific gray matter (GM) atrophy and to explore correlations between GM and cognition in PD. Magnetic resonance images of 42 newly diagnosed PD patients (of which 11 had MCI) and 37 normal controls were analyzed using voxel-based morphometry. Analyses comparing groups showed no regional atrophy, and in patients there were no significant correlations between cognitive domain test performance and GM loss. In conclusion, GM atrophy does not seem to be a major feature of cognitive dysfunction in incident PD.
CC :	002B17; 002B17G
FD :	Maladie de Parkinson; Atrophie; Déficit cognitif léger; Trouble cognitif; Pathologie du système nerveux; Cognition; Imagerie RMN; Voxel; Morphométrie; Encéphale
FG :	Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Système nerveux central
ED :	Parkinson disease; Atrophy; mild cognitive impairment; Cognitive disorder; Nervous system diseases; Cognition; Nuclear magnetic resonance imaging; Voxel; Morphometry; Encephalon
EG :	Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Central nervous system
SD :	Parkinson enfermedad; Atrofia; Disturbio cognitivo ligero; Trastorno cognitivo; Sistema nervioso patología; Cognición; Imaginería RMN; Voxel; Morfometría; Encéfalo
LO :	INIST-20953.354000181079390160
ID :	10-0233228

Links to Exploration step

Pascal:10-0233228

Le document en format XML

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<author><name sortKey="Alves, Guido" sort="Alves, Guido" uniqKey="Alves G" first="Guido" last="Alves">Guido Alves</name>
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<author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Gray Matter Correlations of Cognition in Incident Parkinson's Disease</title>
<author><name sortKey="Dalaker, Turi O" sort="Dalaker, Turi O" uniqKey="Dalaker T" first="Turi O." last="Dalaker">Turi O. Dalaker</name>
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<s2>Buffalo, New York</s2>
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<affiliation><inist:fA14 i1="02"><s1>Department of Radiology, Stavanger University Hospital</s1>
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<author><name sortKey="Zivadinov, Robert" sort="Zivadinov, Robert" uniqKey="Zivadinov R" first="Robert" last="Zivadinov">Robert Zivadinov</name>
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<author><name sortKey="Larsen, Jan P" sort="Larsen, Jan P" uniqKey="Larsen J" first="Jan P." last="Larsen">Jan P. Larsen</name>
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<affiliation><inist:fA14 i1="05"><s1>Department of Neurology, Stavanger University Hospital</s1>
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<author><name sortKey="Beyer, Mona K" sort="Beyer, Mona K" uniqKey="Beyer M" first="Mona K." last="Beyer">Mona K. Beyer</name>
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<sZ>1 aut.</sZ>
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<affiliation><inist:fA14 i1="03"><s1>The Norwegian Centre for Movement Disorders, Stavanger University Hospital</s1>
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<affiliation><inist:fA14 i1="04"><s1>Department of Neurology, The Jacobs Neurological Institute, State University of New York at Buffalo</s1>
<s2>Buffalo, New York</s2>
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<author><name sortKey="Alves, Guido" sort="Alves, Guido" uniqKey="Alves G" first="Guido" last="Alves">Guido Alves</name>
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<affiliation><inist:fA14 i1="05"><s1>Department of Neurology, Stavanger University Hospital</s1>
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<sZ>3 aut.</sZ>
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</inist:fA14>
</affiliation>
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<author><name sortKey="Bronnick, Kolbjorn" sort="Bronnick, Kolbjorn" uniqKey="Bronnick K" first="Kolbjorn" last="Bronnick">Kolbjorn Bronnick</name>
<affiliation><inist:fA14 i1="03"><s1>The Norwegian Centre for Movement Disorders, Stavanger University Hospital</s1>
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<s3>NOR</s3>
<sZ>1 aut.</sZ>
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<author><name sortKey="Tysnes, Ole Bjorn" sort="Tysnes, Ole Bjorn" uniqKey="Tysnes O" first="Ole-Bjorn" last="Tysnes">Ole-Bjorn Tysnes</name>
<affiliation><inist:fA14 i1="06"><s1>Institute of Clinical Medicine, University of Bergen</s1>
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<s3>NOR</s3>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="07"><s1>Department of Neurology, Haukeland University Hospital</s1>
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<s3>NOR</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Antulov, Ronald" sort="Antulov, Ronald" uniqKey="Antulov R" first="Ronald" last="Antulov">Ronald Antulov</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Buffalo Neuroimaging Analysis Center, State University of New York at Buffalo</s1>
<s2>Buffalo, New York</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
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<sZ>10 aut.</sZ>
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<affiliation><inist:fA14 i1="08"><s1>Department of Radiology, Clinical Hospital Centre Rijeka</s1>
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<author><name sortKey="Dwyer, Michael G" sort="Dwyer, Michael G" uniqKey="Dwyer M" first="Michael G." last="Dwyer">Michael G. Dwyer</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, Buffalo Neuroimaging Analysis Center, State University of New York at Buffalo</s1>
<s2>Buffalo, New York</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
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<author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name>
<affiliation><inist:fA14 i1="03"><s1>The Norwegian Centre for Movement Disorders, Stavanger University Hospital</s1>
<s2>Stavanger</s2>
<s3>NOR</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
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<sZ>11 aut.</sZ>
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<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2010">2010</date>
</imprint>
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<seriesStmt><title level="j" type="main">Movement disorders</title>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Atrophy</term>
<term>Cognition</term>
<term>Cognitive disorder</term>
<term>Encephalon</term>
<term>Morphometry</term>
<term>Nervous system diseases</term>
<term>Nuclear magnetic resonance imaging</term>
<term>Parkinson disease</term>
<term>Voxel</term>
<term>mild cognitive impairment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term>
<term>Atrophie</term>
<term>Déficit cognitif léger</term>
<term>Trouble cognitif</term>
<term>Pathologie du   système nerveux</term>
<term>Cognition</term>
<term>Imagerie RMN</term>
<term>Voxel</term>
<term>Morphométrie</term>
<term>Encéphale</term>
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<front><div type="abstract" xml:lang="en">We aimed to investigate whether mild cognitive impairment (MCI) in Parkinson's disease (PD) is characterized by region-specific gray matter (GM) atrophy and to explore correlations between GM and cognition in PD. Magnetic resonance images of 42 newly diagnosed PD patients (of which 11 had MCI) and 37 normal controls were analyzed using voxel-based morphometry. Analyses comparing groups showed no regional atrophy, and in patients there were no significant correlations between cognitive domain test performance and GM loss. In conclusion, GM atrophy does not seem to be a major feature of cognitive dysfunction in incident PD.</div>
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<fA08 i1="01" i2="1" l="ENG"><s1>Gray Matter Correlations of Cognition in Incident Parkinson's Disease</s1>
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<fA14 i1="04"><s1>Department of Neurology, The Jacobs Neurological Institute, State University of New York at Buffalo</s1>
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<fA14 i1="07"><s1>Department of Neurology, Haukeland University Hospital</s1>
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<sZ>8 aut.</sZ>
</fA14>
<fA14 i1="08"><s1>Department of Radiology, Clinical Hospital Centre Rijeka</s1>
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<sZ>9 aut.</sZ>
</fA14>
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<fA60><s1>P</s1>
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<fC01 i1="01" l="ENG"><s0>We aimed to investigate whether mild cognitive impairment (MCI) in Parkinson's disease (PD) is characterized by region-specific gray matter (GM) atrophy and to explore correlations between GM and cognition in PD. Magnetic resonance images of 42 newly diagnosed PD patients (of which 11 had MCI) and 37 normal controls were analyzed using voxel-based morphometry. Analyses comparing groups showed no regional atrophy, and in patients there were no significant correlations between cognitive domain test performance and GM loss. In conclusion, GM atrophy does not seem to be a major feature of cognitive dysfunction in incident PD.</s0>
</fC01>
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<fC02 i1="02" i2="X"><s0>002B17G</s0>
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<fC03 i1="01" i2="X" l="FRE"><s0>Maladie de Parkinson</s0>
<s2>NM</s2>
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<fC03 i1="01" i2="X" l="ENG"><s0>Parkinson disease</s0>
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<s5>02</s5>
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<s5>03</s5>
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<fC03 i1="03" i2="X" l="ENG"><s0>mild cognitive impairment</s0>
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<fC03 i1="08" i2="X" l="SPA"><s0>Voxel</s0>
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<server><NO>PASCAL 10-0233228 INIST</NO>
<ET>Gray Matter Correlations of Cognition in Incident Parkinson's Disease</ET>
<AU>DALAKER (Turi O.); ZIVADINOV (Robert); LARSEN (Jan P.); BEYER (Mona K.); COX (Jennifer L.); ALVES (Guido); BRONNICK (Kolbjorn); TYSNES (Ole-Bjorn); ANTULOV (Ronald); DWYER (Michael G.); AARSLAND (Dag)</AU>
<AF>Department of Neurology, Buffalo Neuroimaging Analysis Center, State University of New York at Buffalo/Buffalo, New York/Etats-Unis (1 aut., 2 aut., 9 aut., 10 aut.); Department of Radiology, Stavanger University Hospital/Stavanger/Norvège (1 aut., 4 aut.); The Norwegian Centre for Movement Disorders, Stavanger University Hospital/Stavanger/Norvège (1 aut., 3 aut., 4 aut., 6 aut., 7 aut., 11 aut.); Department of Neurology, The Jacobs Neurological Institute, State University of New York at Buffalo/Buffalo, New York/Etats-Unis (2 aut., 5 aut.); Department of Neurology, Stavanger University Hospital/Stavanger/Norvège (3 aut., 6 aut.); Institute of Clinical Medicine, University of Bergen/Bergen/Norvège (3 aut., 8 aut., 11 aut.); Department of Neurology, Haukeland University Hospital/Bergen/Norvège (8 aut.); Department of Radiology, Clinical Hospital Centre Rijeka/Rijeka/Croatie (9 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 5; Pp. 629-633; Bibl. 17 ref.</SO>
<LA>Anglais</LA>
<EA>We aimed to investigate whether mild cognitive impairment (MCI) in Parkinson's disease (PD) is characterized by region-specific gray matter (GM) atrophy and to explore correlations between GM and cognition in PD. Magnetic resonance images of 42 newly diagnosed PD patients (of which 11 had MCI) and 37 normal controls were analyzed using voxel-based morphometry. Analyses comparing groups showed no regional atrophy, and in patients there were no significant correlations between cognitive domain test performance and GM loss. In conclusion, GM atrophy does not seem to be a major feature of cognitive dysfunction in incident PD.</EA>
<CC>002B17; 002B17G</CC>
<FD>Maladie de Parkinson; Atrophie; Déficit cognitif léger; Trouble cognitif; Pathologie du   système nerveux; Cognition; Imagerie RMN; Voxel; Morphométrie; Encéphale</FD>
<FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du   système nerveux central; Système nerveux central</FG>
<ED>Parkinson disease; Atrophy; mild cognitive impairment; Cognitive disorder; Nervous system diseases; Cognition; Nuclear magnetic resonance imaging; Voxel; Morphometry; Encephalon</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Central nervous system</EG>
<SD>Parkinson enfermedad; Atrofia; Disturbio cognitivo ligero; Trastorno cognitivo; Sistema nervioso patología; Cognición; Imaginería RMN; Voxel; Morfometría; Encéfalo</SD>
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   |texte=   Gray Matter Correlations of Cognition in Incident Parkinson's Disease
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	Movement Disorders (revue)
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Movement Disorders (revue)

Gray Matter Correlations of Cognition in Incident Parkinson's Disease

Gray Matter Correlations of Cognition in Incident Parkinson's Disease

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