MovDisordV3, PascalFrancis, Corpus, bibRecord, 000A64

Imitation in Patients with Gilles de la Tourette Syndrome: A Behavioral Study

Identifieur interne : 000A64 ( PascalFrancis/Corpus ); précédent : 000A63; suivant : 000A65

Imitation in Patients with Gilles de la Tourette Syndrome: A Behavioral Study

Auteurs : Melanie Jonas ; Götz Thomalla ; Katja Biermann-Ruben ; Hartwig Roman Siebner ; Kirsten Müller-Vahl ; Tobias B Umer ; Christian Gerloff ; Alfons Schnitzler ; Michael Orth ; Alexander Münchau

Source :

Movement disorders [ 0885-3185 ] ; 2010.

RBID : Pascal:10-0315059

Descripteurs français

Pascal (Inist)
- Syndrome de Gilles de la Tourette, Pathologie du système nerveux, Homme, Temps réaction.

English descriptors

KwdEn :
- Gilles de la Tourette syndrome, Human, Nervous system diseases, Reaction time.

Abstract

Echophenomena in Gilles de la Tourette syndrome (GTS) may relate to deficient processing of observed biological movements. This would be reflected in altered effects of movement observation on motor responses in these patients. We studied reaction times in 11 unmedicated GTS patients without psychiatric comorbidity and healthy subjects. In experiment 1, participants imitated single biological finger movement stimuli or nonbiological dot movement stimuli immediately. In experiment 2, participants responded to a tone while viewing biological or nonbiological movement stimuli that were either compatible (identical) or incompatible (different) with their response. In experiment 1, both patients and healthy subjects responded faster to single biological than to nonbiological stimuli. In experiment 2, biological stimuli caused a larger compatibility-effect in responses than nonbiological stimuli in both groups, provided stimulus presentation and response initiation coincided. Healthy subjects responded faster to compatible biological than nonbiological stimuli. In contrast, GTS patients responded slower to incompatible biological than nonbiological stimuli. Patients' mean reaction time in experiment 2 correlated with phonic tic-frequency. Motor facilitation by observing biological movements appears to rely on concomitance of stimuli and responses in GTS patients and healthy individuals. Differing behavioral effects of movement observation in GTS might reflect altered activation of an action observation-execution matching system. To avoid unwanted movements GTS patients probably have to inhibit motor activation induced by observed movement automatically. Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A08	`01`	`1`	`ENG`	`@1 Imitation in Patients with Gilles de la Tourette Syndrome: A Behavioral Study`
A11	`01`	`1`		`@1 JONAS (Melanie)`
A11	`02`	`1`		`@1 THOMALLA (Götz)`
A11	`03`	`1`		`@1 BIERMANN-RUBEN (Katja)`
A11	`04`	`1`		`@1 ROMAN SIEBNER (Hartwig)`
A11	`05`	`1`		`@1 MÜLLER-VAHL (Kirsten)`
A11	`06`	`1`		`@1 BÄUMER (Tobias)`
A11	`07`	`1`		`@1 GERLOFF (Christian)`
A11	`08`	`1`		`@1 SCHNITZLER (Alfons)`
A11	`09`	`1`		`@1 ORTH (Michael)`
A11	`10`	`1`		`@1 MÜNCHAU (Alexander)`
A14	`01`			`@1 Department of Neurology, University Medical Center Hambut-g-Eppendorf @2 Hamburg @3 DEU @Z 1 aut. @Z 2 aut. @Z 6 aut. @Z 7 aut. @Z 10 aut.`
A14	`02`			`@1 Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf @2 Hamburg @3 DEU @Z 1 aut.`
A14	`03`			`@1 Department of Neurology, MEG Laboratory, Dusseldorf University Hospital @2 Düsseldorf @3 DEU @Z 3 aut. @Z 8 aut.`
A14	`04`			`@1 Institute of Clinical Neuroscience and Medical Psychology, Heinrich-Heine-University @2 Düsseldorf @3 DEU @Z 3 aut. @Z 8 aut.`
A14	`05`			`@1 Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre @2 Copenhagen @3 DNK @Z 4 aut.`
A14	`06`			`@1 NeuroImage Nord @2 Hamburg-Kiel-Lübeck @3 DEU @Z 4 aut.`
A14	`07`			`@1 Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School @2 Hannover @3 DEU @Z 5 aut.`
A14	`08`			`@1 Department of Neurology, Ulm University Hospital @2 Ulm @3 DEU @Z 9 aut.`
A20				`@1 991-999`
A21				`@1 2010`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20953 @5 354000170524820040`
A44				`@0 0000 @1 © 2010 INIST-CNRS. All rights reserved.`
A45				`@0 37 ref.`
A47	`01`	`1`		`@0 10-0315059`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 Echophenomena in Gilles de la Tourette syndrome (GTS) may relate to deficient processing of observed biological movements. This would be reflected in altered effects of movement observation on motor responses in these patients. We studied reaction times in 11 unmedicated GTS patients without psychiatric comorbidity and healthy subjects. In experiment 1, participants imitated single biological finger movement stimuli or nonbiological dot movement stimuli immediately. In experiment 2, participants responded to a tone while viewing biological or nonbiological movement stimuli that were either compatible (identical) or incompatible (different) with their response. In experiment 1, both patients and healthy subjects responded faster to single biological than to nonbiological stimuli. In experiment 2, biological stimuli caused a larger compatibility-effect in responses than nonbiological stimuli in both groups, provided stimulus presentation and response initiation coincided. Healthy subjects responded faster to compatible biological than nonbiological stimuli. In contrast, GTS patients responded slower to incompatible biological than nonbiological stimuli. Patients' mean reaction time in experiment 2 correlated with phonic tic-frequency. Motor facilitation by observing biological movements appears to rely on concomitance of stimuli and responses in GTS patients and healthy individuals. Differing behavioral effects of movement observation in GTS might reflect altered activation of an action observation-execution matching system. To avoid unwanted movements GTS patients probably have to inhibit motor activation induced by observed movement automatically. Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients.
C02	`01`	`X`		`@0 002B17`
C02	`02`	`X`		`@0 002B17F`
C03	`01`	`X`	`FRE`	`@0 Syndrome de Gilles de la Tourette @5 01`
C03	`01`	`X`	`ENG`	`@0 Gilles de la Tourette syndrome @5 01`
C03	`01`	`X`	`SPA`	`@0 Gilles de la Tourette síndrome @5 01`
C03	`02`	`X`	`FRE`	`@0 Pathologie du système nerveux @5 02`
C03	`02`	`X`	`ENG`	`@0 Nervous system diseases @5 02`
C03	`02`	`X`	`SPA`	`@0 Sistema nervioso patología @5 02`
C03	`03`	`X`	`FRE`	`@0 Homme @5 09`
C03	`03`	`X`	`ENG`	`@0 Human @5 09`
C03	`03`	`X`	`SPA`	`@0 Hombre @5 09`
C03	`04`	`X`	`FRE`	`@0 Temps réaction @5 10`
C03	`04`	`X`	`ENG`	`@0 Reaction time @5 10`
C03	`04`	`X`	`SPA`	`@0 Tiempo reacción @5 10`
C07	`01`	`X`	`FRE`	`@0 Pathologie de l'encéphale @5 37`
C07	`01`	`X`	`ENG`	`@0 Cerebral disorder @5 37`
C07	`01`	`X`	`SPA`	`@0 Encéfalo patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Maladie dégénérative @5 38`
C07	`02`	`X`	`ENG`	`@0 Degenerative disease @5 38`
C07	`02`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 38`
C07	`03`	`X`	`FRE`	`@0 Pathologie du système nerveux central @5 39`
C07	`03`	`X`	`ENG`	`@0 Central nervous system disease @5 39`
C07	`03`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 39`
N21				`@1 200`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 10-0315059 INIST
ET :	Imitation in Patients with Gilles de la Tourette Syndrome: A Behavioral Study
AU :	JONAS (Melanie); THOMALLA (Götz); BIERMANN-RUBEN (Katja); ROMAN SIEBNER (Hartwig); MÜLLER-VAHL (Kirsten); BÄUMER (Tobias); GERLOFF (Christian); SCHNITZLER (Alfons); ORTH (Michael); MÜNCHAU (Alexander)
AF :	Department of Neurology, University Medical Center Hambut-g-Eppendorf/Hamburg/Allemagne (1 aut., 2 aut., 6 aut., 7 aut., 10 aut.); Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf/Hamburg/Allemagne (1 aut.); Department of Neurology, MEG Laboratory, Dusseldorf University Hospital/Düsseldorf/Allemagne (3 aut., 8 aut.); Institute of Clinical Neuroscience and Medical Psychology, Heinrich-Heine-University/Düsseldorf/Allemagne (3 aut., 8 aut.); Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre/Copenhagen/Danemark (4 aut.); NeuroImage Nord/Hamburg-Kiel-Lübeck/Allemagne (4 aut.); Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School/Hannover/Allemagne (5 aut.); Department of Neurology, Ulm University Hospital/Ulm/Allemagne (9 aut.)
DT :	Publication en série; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 8; Pp. 991-999; Bibl. 37 ref.
LA :	Anglais
EA :	Echophenomena in Gilles de la Tourette syndrome (GTS) may relate to deficient processing of observed biological movements. This would be reflected in altered effects of movement observation on motor responses in these patients. We studied reaction times in 11 unmedicated GTS patients without psychiatric comorbidity and healthy subjects. In experiment 1, participants imitated single biological finger movement stimuli or nonbiological dot movement stimuli immediately. In experiment 2, participants responded to a tone while viewing biological or nonbiological movement stimuli that were either compatible (identical) or incompatible (different) with their response. In experiment 1, both patients and healthy subjects responded faster to single biological than to nonbiological stimuli. In experiment 2, biological stimuli caused a larger compatibility-effect in responses than nonbiological stimuli in both groups, provided stimulus presentation and response initiation coincided. Healthy subjects responded faster to compatible biological than nonbiological stimuli. In contrast, GTS patients responded slower to incompatible biological than nonbiological stimuli. Patients' mean reaction time in experiment 2 correlated with phonic tic-frequency. Motor facilitation by observing biological movements appears to rely on concomitance of stimuli and responses in GTS patients and healthy individuals. Differing behavioral effects of movement observation in GTS might reflect altered activation of an action observation-execution matching system. To avoid unwanted movements GTS patients probably have to inhibit motor activation induced by observed movement automatically. Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients.
CC :	002B17; 002B17F
FD :	Syndrome de Gilles de la Tourette; Pathologie du système nerveux; Homme; Temps réaction
FG :	Pathologie de l'encéphale; Maladie dégénérative; Pathologie du système nerveux central
ED :	Gilles de la Tourette syndrome; Nervous system diseases; Human; Reaction time
EG :	Cerebral disorder; Degenerative disease; Central nervous system disease
SD :	Gilles de la Tourette síndrome; Sistema nervioso patología; Hombre; Tiempo reacción
LO :	INIST-20953.354000170524820040
ID :	10-0315059

Links to Exploration step

Pascal:10-0315059

Le document en format XML

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<author><name sortKey="Gerloff, Christian" sort="Gerloff, Christian" uniqKey="Gerloff C" first="Christian" last="Gerloff">Christian Gerloff</name>
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<author><name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
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<author><name sortKey="Orth, Michael" sort="Orth, Michael" uniqKey="Orth M" first="Michael" last="Orth">Michael Orth</name>
<affiliation><inist:fA14 i1="08"><s1>Department of Neurology, Ulm University Hospital</s1>
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<author><name sortKey="Munchau, Alexander" sort="Munchau, Alexander" uniqKey="Munchau A" first="Alexander" last="Münchau">Alexander Münchau</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University Medical Center Hambut-g-Eppendorf</s1>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Imitation in Patients with Gilles de la Tourette Syndrome: A Behavioral Study</title>
<author><name sortKey="Jonas, Melanie" sort="Jonas, Melanie" uniqKey="Jonas M" first="Melanie" last="Jonas">Melanie Jonas</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University Medical Center Hambut-g-Eppendorf</s1>
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<affiliation><inist:fA14 i1="02"><s1>Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf</s1>
<s2>Hamburg</s2>
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</inist:fA14>
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</author>
<author><name sortKey="Thomalla, Gotz" sort="Thomalla, Gotz" uniqKey="Thomalla G" first="Götz" last="Thomalla">Götz Thomalla</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University Medical Center Hambut-g-Eppendorf</s1>
<s2>Hamburg</s2>
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<author><name sortKey="Biermann Ruben, Katja" sort="Biermann Ruben, Katja" uniqKey="Biermann Ruben K" first="Katja" last="Biermann-Ruben">Katja Biermann-Ruben</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Neurology, MEG Laboratory, Dusseldorf University Hospital</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="04"><s1>Institute of Clinical Neuroscience and Medical Psychology, Heinrich-Heine-University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
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</author>
<author><name sortKey="Roman Siebner, Hartwig" sort="Roman Siebner, Hartwig" uniqKey="Roman Siebner H" first="Hartwig" last="Roman Siebner">Hartwig Roman Siebner</name>
<affiliation><inist:fA14 i1="05"><s1>Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre</s1>
<s2>Copenhagen</s2>
<s3>DNK</s3>
<sZ>4 aut.</sZ>
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<affiliation><inist:fA14 i1="06"><s1>NeuroImage Nord</s1>
<s2>Hamburg-Kiel-Lübeck</s2>
<s3>DEU</s3>
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</author>
<author><name sortKey="Muller Vahl, Kirsten" sort="Muller Vahl, Kirsten" uniqKey="Muller Vahl K" first="Kirsten" last="Müller-Vahl">Kirsten Müller-Vahl</name>
<affiliation><inist:fA14 i1="07"><s1>Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School</s1>
<s2>Hannover</s2>
<s3>DEU</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="B Umer, Tobias" sort="B Umer, Tobias" uniqKey="B Umer T" first="Tobias" last="B Umer">Tobias B Umer</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University Medical Center Hambut-g-Eppendorf</s1>
<s2>Hamburg</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
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</inist:fA14>
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<author><name sortKey="Gerloff, Christian" sort="Gerloff, Christian" uniqKey="Gerloff C" first="Christian" last="Gerloff">Christian Gerloff</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University Medical Center Hambut-g-Eppendorf</s1>
<s2>Hamburg</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
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<author><name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
<affiliation><inist:fA14 i1="03"><s1>Department of Neurology, MEG Laboratory, Dusseldorf University Hospital</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="04"><s1>Institute of Clinical Neuroscience and Medical Psychology, Heinrich-Heine-University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>3 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Orth, Michael" sort="Orth, Michael" uniqKey="Orth M" first="Michael" last="Orth">Michael Orth</name>
<affiliation><inist:fA14 i1="08"><s1>Department of Neurology, Ulm University Hospital</s1>
<s2>Ulm</s2>
<s3>DEU</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Munchau, Alexander" sort="Munchau, Alexander" uniqKey="Munchau A" first="Alexander" last="Münchau">Alexander Münchau</name>
<affiliation><inist:fA14 i1="01"><s1>Department of Neurology, University Medical Center Hambut-g-Eppendorf</s1>
<s2>Hamburg</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>6 aut.</sZ>
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</author>
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<series><title level="j" type="main">Movement disorders</title>
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<term>Reaction time</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Syndrome de Gilles de la Tourette</term>
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<front><div type="abstract" xml:lang="en">Echophenomena in Gilles de la Tourette syndrome (GTS) may relate to deficient processing of observed biological movements. This would be reflected in altered effects of movement observation on motor responses in these patients. We studied reaction times in 11 unmedicated GTS patients without psychiatric comorbidity and healthy subjects. In experiment 1, participants imitated single biological finger movement stimuli or nonbiological dot movement stimuli immediately. In experiment 2, participants responded to a tone while viewing biological or nonbiological movement stimuli that were either compatible (identical) or incompatible (different) with their response. In experiment 1, both patients and healthy subjects responded faster to single biological than to nonbiological stimuli. In experiment 2, biological stimuli caused a larger compatibility-effect in responses than nonbiological stimuli in both groups, provided stimulus presentation and response initiation coincided. Healthy subjects responded faster to compatible biological than nonbiological stimuli. In contrast, GTS patients responded slower to incompatible biological than nonbiological stimuli. Patients' mean reaction time in experiment 2 correlated with phonic tic-frequency. Motor facilitation by observing biological movements appears to rely on concomitance of stimuli and responses in GTS patients and healthy individuals. Differing behavioral effects of movement observation in GTS might reflect altered activation of an action observation-execution matching system. To avoid unwanted movements GTS patients probably have to inhibit motor activation induced by observed movement automatically. Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients.</div>
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<ET>Imitation in Patients with Gilles de la Tourette Syndrome: A Behavioral Study</ET>
<AU>JONAS (Melanie); THOMALLA (Götz); BIERMANN-RUBEN (Katja); ROMAN SIEBNER (Hartwig); MÜLLER-VAHL (Kirsten); BÄUMER (Tobias); GERLOFF (Christian); SCHNITZLER (Alfons); ORTH (Michael); MÜNCHAU (Alexander)</AU>
<AF>Department of Neurology, University Medical Center Hambut-g-Eppendorf/Hamburg/Allemagne (1 aut., 2 aut., 6 aut., 7 aut., 10 aut.); Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf/Hamburg/Allemagne (1 aut.); Department of Neurology, MEG Laboratory, Dusseldorf University Hospital/Düsseldorf/Allemagne (3 aut., 8 aut.); Institute of Clinical Neuroscience and Medical Psychology, Heinrich-Heine-University/Düsseldorf/Allemagne (3 aut., 8 aut.); Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre/Copenhagen/Danemark (4 aut.); NeuroImage Nord/Hamburg-Kiel-Lübeck/Allemagne (4 aut.); Clinic of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School/Hannover/Allemagne (5 aut.); Department of Neurology, Ulm University Hospital/Ulm/Allemagne (9 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 8; Pp. 991-999; Bibl. 37 ref.</SO>
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<EA>Echophenomena in Gilles de la Tourette syndrome (GTS) may relate to deficient processing of observed biological movements. This would be reflected in altered effects of movement observation on motor responses in these patients. We studied reaction times in 11 unmedicated GTS patients without psychiatric comorbidity and healthy subjects. In experiment 1, participants imitated single biological finger movement stimuli or nonbiological dot movement stimuli immediately. In experiment 2, participants responded to a tone while viewing biological or nonbiological movement stimuli that were either compatible (identical) or incompatible (different) with their response. In experiment 1, both patients and healthy subjects responded faster to single biological than to nonbiological stimuli. In experiment 2, biological stimuli caused a larger compatibility-effect in responses than nonbiological stimuli in both groups, provided stimulus presentation and response initiation coincided. Healthy subjects responded faster to compatible biological than nonbiological stimuli. In contrast, GTS patients responded slower to incompatible biological than nonbiological stimuli. Patients' mean reaction time in experiment 2 correlated with phonic tic-frequency. Motor facilitation by observing biological movements appears to rely on concomitance of stimuli and responses in GTS patients and healthy individuals. Differing behavioral effects of movement observation in GTS might reflect altered activation of an action observation-execution matching system. To avoid unwanted movements GTS patients probably have to inhibit motor activation induced by observed movement automatically. Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients.</EA>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Imitation in Patients with Gilles de la Tourette Syndrome: A Behavioral Study

Imitation in Patients with Gilles de la Tourette Syndrome: A Behavioral Study

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