Movement Disorders (revue)

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Chronic Deep Brain Stimulation in Patients with Tardive Dystonia Without a History of Major Psychosis

Identifieur interne : 000969 ( PascalFrancis/Corpus ); précédent : 000968; suivant : 000970

Chronic Deep Brain Stimulation in Patients with Tardive Dystonia Without a History of Major Psychosis

Auteurs : Hans-Holger Capelle ; Christian Blahak ; Christoph Schrader ; Hansjörg Baezner ; Thomas M. Kinfe ; Jan Herzog ; Reinhard Dengler ; Joachim K. Krauss

Source :

RBID : Pascal:10-0377369

Descripteurs français

English descriptors

Abstract

Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for "mild depression" or "neurasthenia." Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long-acting depot neuroleptics prescribed for mild depression or "nervousness." Assessment included the Burke-Fahn-Marsden (BFM) scale preoperatively and at 12 months follow-up. Extended follow-up was available at a mean of 27.3 months postoperatively (range 16-36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS, Mean improvement at 12 months was 77% for the BFM motor score (range, 45-91%; P = 0.043), and 84% at the last available follow-up (range, 70-91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow-up for up to 3 years.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 25
A06       @2 10
A08 01  1  ENG  @1 Chronic Deep Brain Stimulation in Patients with Tardive Dystonia Without a History of Major Psychosis
A11 01  1    @1 CAPELLE (Hans-Holger)
A11 02  1    @1 BLAHAK (Christian)
A11 03  1    @1 SCHRADER (Christoph)
A11 04  1    @1 BAEZNER (Hansjörg)
A11 05  1    @1 KINFE (Thomas M.)
A11 06  1    @1 HERZOG (Jan)
A11 07  1    @1 DENGLER (Reinhard)
A11 08  1    @1 KRAUSS (Joachim K.)
A14 01      @1 Department of Neurosurgery, Medical School Hannover, MHH @2 Hannover @3 DEU @Z 1 aut. @Z 5 aut. @Z 8 aut.
A14 02      @1 Department of Neurology, University Hospital Mannheim @2 Mannheim @3 DEU @Z 2 aut. @Z 4 aut.
A14 03      @1 Department of Neurology, Medical School Hannover, MHH @2 Hannover @3 DEU @Z 3 aut. @Z 7 aut.
A14 04      @1 Department of Neurology, University Hospital Kiel @2 Kiel @3 DEU @Z 6 aut.
A20       @1 1477-1481
A21       @1 2010
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000194762830210
A44       @0 0000 @1 © 2010 INIST-CNRS. All rights reserved.
A45       @0 26 ref.
A47 01  1    @0 10-0377369
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for "mild depression" or "neurasthenia." Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long-acting depot neuroleptics prescribed for mild depression or "nervousness." Assessment included the Burke-Fahn-Marsden (BFM) scale preoperatively and at 12 months follow-up. Extended follow-up was available at a mean of 27.3 months postoperatively (range 16-36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS, Mean improvement at 12 months was 77% for the BFM motor score (range, 45-91%; P = 0.043), and 84% at the last available follow-up (range, 70-91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow-up for up to 3 years.
C02 01  X    @0 002B17
C02 02  X    @0 002B17H
C03 01  X  FRE  @0 Dystonie @5 01
C03 01  X  ENG  @0 Dystonia @5 01
C03 01  X  SPA  @0 Distonía @5 01
C03 02  X  FRE  @0 Psychose @5 02
C03 02  X  ENG  @0 Psychosis @5 02
C03 02  X  SPA  @0 Psicosis @5 02
C03 03  X  FRE  @0 Pathologie du système nerveux @5 03
C03 03  X  ENG  @0 Nervous system diseases @5 03
C03 03  X  SPA  @0 Sistema nervioso patología @5 03
C03 04  X  FRE  @0 Chronique @5 09
C03 04  X  ENG  @0 Chronic @5 09
C03 04  X  SPA  @0 Crónico @5 09
C03 05  X  FRE  @0 Homme @5 10
C03 05  X  ENG  @0 Human @5 10
C03 05  X  SPA  @0 Hombre @5 10
C03 06  X  FRE  @0 Encéphale @5 11
C03 06  X  ENG  @0 Encephalon @5 11
C03 06  X  SPA  @0 Encéfalo @5 11
C03 07  X  FRE  @0 Stimulation cérébrale profonde @4 CD @5 96
C03 07  X  ENG  @0 Deep brain stimulation @4 CD @5 96
C07 01  X  FRE  @0 Syndrome extrapyramidal @5 37
C07 01  X  ENG  @0 Extrapyramidal syndrome @5 37
C07 01  X  SPA  @0 Extrapiramidal síndrome @5 37
C07 02  X  FRE  @0 Mouvement involontaire @5 38
C07 02  X  ENG  @0 Involuntary movement @5 38
C07 02  X  SPA  @0 Movimiento involuntario @5 38
C07 03  X  FRE  @0 Pathologie du muscle strié @5 39
C07 03  X  ENG  @0 Striated muscle disease @5 39
C07 03  X  SPA  @0 Músculo estriado patología @5 39
C07 04  X  FRE  @0 Trouble neurologique @5 41
C07 04  X  ENG  @0 Neurological disorder @5 41
C07 04  X  SPA  @0 Trastorno neurológico @5 41
C07 05  X  FRE  @0 Système nerveux central @5 42
C07 05  X  ENG  @0 Central nervous system @5 42
C07 05  X  SPA  @0 Sistema nervioso central @5 42
C07 06  X  FRE  @0 Pathologie de l'encéphale @5 43
C07 06  X  ENG  @0 Cerebral disorder @5 43
C07 06  X  SPA  @0 Encéfalo patología @5 43
C07 07  X  FRE  @0 Pathologie du système nerveux central @5 44
C07 07  X  ENG  @0 Central nervous system disease @5 44
C07 07  X  SPA  @0 Sistema nervosio central patología @5 44
N21       @1 242
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 10-0377369 INIST
ET : Chronic Deep Brain Stimulation in Patients with Tardive Dystonia Without a History of Major Psychosis
AU : CAPELLE (Hans-Holger); BLAHAK (Christian); SCHRADER (Christoph); BAEZNER (Hansjörg); KINFE (Thomas M.); HERZOG (Jan); DENGLER (Reinhard); KRAUSS (Joachim K.)
AF : Department of Neurosurgery, Medical School Hannover, MHH/Hannover/Allemagne (1 aut., 5 aut., 8 aut.); Department of Neurology, University Hospital Mannheim/Mannheim/Allemagne (2 aut., 4 aut.); Department of Neurology, Medical School Hannover, MHH/Hannover/Allemagne (3 aut., 7 aut.); Department of Neurology, University Hospital Kiel/Kiel/Allemagne (6 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 10; Pp. 1477-1481; Bibl. 26 ref.
LA : Anglais
EA : Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for "mild depression" or "neurasthenia." Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long-acting depot neuroleptics prescribed for mild depression or "nervousness." Assessment included the Burke-Fahn-Marsden (BFM) scale preoperatively and at 12 months follow-up. Extended follow-up was available at a mean of 27.3 months postoperatively (range 16-36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS, Mean improvement at 12 months was 77% for the BFM motor score (range, 45-91%; P = 0.043), and 84% at the last available follow-up (range, 70-91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow-up for up to 3 years.
CC : 002B17; 002B17H
FD : Dystonie; Psychose; Pathologie du système nerveux; Chronique; Homme; Encéphale; Stimulation cérébrale profonde
FG : Syndrome extrapyramidal; Mouvement involontaire; Pathologie du muscle strié; Trouble neurologique; Système nerveux central; Pathologie de l'encéphale; Pathologie du système nerveux central
ED : Dystonia; Psychosis; Nervous system diseases; Chronic; Human; Encephalon; Deep brain stimulation
EG : Extrapyramidal syndrome; Involuntary movement; Striated muscle disease; Neurological disorder; Central nervous system; Cerebral disorder; Central nervous system disease
SD : Distonía; Psicosis; Sistema nervioso patología; Crónico; Hombre; Encéfalo
LO : INIST-20953.354000194762830210
ID : 10-0377369

Links to Exploration step

Pascal:10-0377369

Le document en format XML

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<div type="abstract" xml:lang="en">Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for "mild depression" or "neurasthenia." Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long-acting depot neuroleptics prescribed for mild depression or "nervousness." Assessment included the Burke-Fahn-Marsden (BFM) scale preoperatively and at 12 months follow-up. Extended follow-up was available at a mean of 27.3 months postoperatively (range 16-36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS, Mean improvement at 12 months was 77% for the BFM motor score (range, 45-91%; P = 0.043), and 84% at the last available follow-up (range, 70-91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow-up for up to 3 years.</div>
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<s2>Kiel</s2>
<s3>DEU</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA20>
<s1>1477-1481</s1>
</fA20>
<fA21>
<s1>2010</s1>
</fA21>
<fA23 i1="01">
<s0>ENG</s0>
</fA23>
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<s1>INIST</s1>
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<s5>354000194762830210</s5>
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<s0>0000</s0>
<s1>© 2010 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45>
<s0>26 ref.</s0>
</fA45>
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<s0>10-0377369</s0>
</fA47>
<fA60>
<s1>P</s1>
</fA60>
<fA61>
<s0>A</s0>
</fA61>
<fA64 i1="01" i2="1">
<s0>Movement disorders</s0>
</fA64>
<fA66 i1="01">
<s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG">
<s0>Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for "mild depression" or "neurasthenia." Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long-acting depot neuroleptics prescribed for mild depression or "nervousness." Assessment included the Burke-Fahn-Marsden (BFM) scale preoperatively and at 12 months follow-up. Extended follow-up was available at a mean of 27.3 months postoperatively (range 16-36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS, Mean improvement at 12 months was 77% for the BFM motor score (range, 45-91%; P = 0.043), and 84% at the last available follow-up (range, 70-91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow-up for up to 3 years.</s0>
</fC01>
<fC02 i1="01" i2="X">
<s0>002B17</s0>
</fC02>
<fC02 i1="02" i2="X">
<s0>002B17H</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE">
<s0>Dystonie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Dystonia</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Distonía</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Psychose</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Psychosis</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Psicosis</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Pathologie du système nerveux</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Nervous system diseases</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Sistema nervioso patología</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE">
<s0>Chronique</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG">
<s0>Chronic</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA">
<s0>Crónico</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE">
<s0>Homme</s0>
<s5>10</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG">
<s0>Human</s0>
<s5>10</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA">
<s0>Hombre</s0>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE">
<s0>Encéphale</s0>
<s5>11</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG">
<s0>Encephalon</s0>
<s5>11</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA">
<s0>Encéfalo</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE">
<s0>Stimulation cérébrale profonde</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG">
<s0>Deep brain stimulation</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Syndrome extrapyramidal</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Extrapyramidal syndrome</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Extrapiramidal síndrome</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Mouvement involontaire</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Involuntary movement</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Movimiento involuntario</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Pathologie du muscle strié</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Striated muscle disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Músculo estriado patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Trouble neurologique</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Neurological disorder</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Trastorno neurológico</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE">
<s0>Système nerveux central</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Central nervous system</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Sistema nervioso central</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE">
<s0>Pathologie de l'encéphale</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Cerebral disorder</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Encéfalo patología</s0>
<s5>43</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE">
<s0>Pathologie du système nerveux central</s0>
<s5>44</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG">
<s0>Central nervous system disease</s0>
<s5>44</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA">
<s0>Sistema nervosio central patología</s0>
<s5>44</s5>
</fC07>
<fN21>
<s1>242</s1>
</fN21>
<fN44 i1="01">
<s1>OTO</s1>
</fN44>
<fN82>
<s1>OTO</s1>
</fN82>
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<NO>PASCAL 10-0377369 INIST</NO>
<ET>Chronic Deep Brain Stimulation in Patients with Tardive Dystonia Without a History of Major Psychosis</ET>
<AU>CAPELLE (Hans-Holger); BLAHAK (Christian); SCHRADER (Christoph); BAEZNER (Hansjörg); KINFE (Thomas M.); HERZOG (Jan); DENGLER (Reinhard); KRAUSS (Joachim K.)</AU>
<AF>Department of Neurosurgery, Medical School Hannover, MHH/Hannover/Allemagne (1 aut., 5 aut., 8 aut.); Department of Neurology, University Hospital Mannheim/Mannheim/Allemagne (2 aut., 4 aut.); Department of Neurology, Medical School Hannover, MHH/Hannover/Allemagne (3 aut., 7 aut.); Department of Neurology, University Hospital Kiel/Kiel/Allemagne (6 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 10; Pp. 1477-1481; Bibl. 26 ref.</SO>
<LA>Anglais</LA>
<EA>Tardive dystonia usually occurs with a delay after neuroleptic exposure in patients with major psychosis. A subgroup of patients, however, is given such medication for "mild depression" or "neurasthenia." Tardive dystonia, in general, may respond favorably to pallidal deep brain stimulation (DBS). Nevertheless, it remains unclear thus far whether or not similar beneficial outcome is achieved with pallidal DBS in different subgroups of patients with tardive dystonia. Four women (mean age 59 years at surgery) underwent stereotactic pallidal DBS in the frame of an observational study. Tardive dystonia occurred secondary to medication with fluspirilene and haloperidol, and injection of long-acting depot neuroleptics prescribed for mild depression or "nervousness." Assessment included the Burke-Fahn-Marsden (BFM) scale preoperatively and at 12 months follow-up. Extended follow-up was available at a mean of 27.3 months postoperatively (range 16-36 months). There were no surgically related complications. All 4 patients experienced sustained statistically significant benefit from pallidal DBS, Mean improvement at 12 months was 77% for the BFM motor score (range, 45-91%; P = 0.043), and 84% at the last available follow-up (range, 70-91%; P = 0.03). This was paralleled by improvement of the BFM disability score. Chronic pallidal DBS in patients with tardive dystonia without a history of major psychosis provides sustained improvement which is similar to that in other subgroups of patients with tardive dystonia. This effect is stable on extended follow-up for up to 3 years.</EA>
<CC>002B17; 002B17H</CC>
<FD>Dystonie; Psychose; Pathologie du système nerveux; Chronique; Homme; Encéphale; Stimulation cérébrale profonde</FD>
<FG>Syndrome extrapyramidal; Mouvement involontaire; Pathologie du muscle strié; Trouble neurologique; Système nerveux central; Pathologie de l'encéphale; Pathologie du système nerveux central</FG>
<ED>Dystonia; Psychosis; Nervous system diseases; Chronic; Human; Encephalon; Deep brain stimulation</ED>
<EG>Extrapyramidal syndrome; Involuntary movement; Striated muscle disease; Neurological disorder; Central nervous system; Cerebral disorder; Central nervous system disease</EG>
<SD>Distonía; Psicosis; Sistema nervioso patología; Crónico; Hombre; Encéfalo</SD>
<LO>INIST-20953.354000194762830210</LO>
<ID>10-0377369</ID>
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