MovDisordV3, PascalFrancis, Corpus, bibRecord, 000922

Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed

Identifieur interne : 000922 ( PascalFrancis/Corpus ); précédent : 000921; suivant : 000923

Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed

Auteurs : Avner Shahar ; Kushang V. Patel ; Richard D. Semba ; Stefania Bandinelli ; Danit R. Shahar ; Louigi Ferrucci ; Jack M. Guralnik

Source :

Movement disorders [ 0885-3185 ] ; 2010.

RBID : Pascal:10-0446308

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Pathologie du système nerveux, Sélénium, Performance, Coordination, Vitesse déplacement, Antioxydant, Personne âgée.

English descriptors

KwdEn :
- Antioxidant, Coordination, Elderly, Nervous system diseases, Parkinson disease, Performance, Selenium, Speed.

Abstract

Parkinson's disease (PD) is a degenerative process affecting the striato nigral system (SN). Its etiology, although obscure, may involve oxidative damage. Selenium, an antioxidant, was shown to protect the SN in animal models. In the current study, we investigate the association between plasma selenium concentrations and the presence of "soft" neurological signs related to the SN. Plasma selenium concentration was assessed in participants of age ≥65 years in the InCHIANTI study, a population-based cohort study in Tuscany, Italy. PD was defined based on standard criteria. "Soft" neurological signs were ascertained by physical examination. A total of 1,012 participants were included. No association was found between the presence of PD and plasma selenium. There was, however, a strong association between plasma selenium and timed performance-based assessments. Lower levels of selenium were significantly associated with decreased performance in neurological tests of coordination among older adults. Prospective studies are needed to further investigate the effects of selenium on SN dysfunction.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 0885-3185`
A03		`1`		`@0 Mov. disord.`
A05				`@2 25`
A06				`@2 12`
A08	`01`	`1`	`ENG`	`@1 Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed`
A11	`01`	`1`		`@1 SHAHAR (Avner)`
A11	`02`	`1`		`@1 PATEL (Kushang V.)`
A11	`03`	`1`		`@1 SEMBA (Richard D.)`
A11	`04`	`1`		`@1 BANDINELLI (Stefania)`
A11	`05`	`1`		`@1 SHAHAR (Danit R.)`
A11	`06`	`1`		`@1 FERRUCCI (Louigi)`
A11	`07`	`1`		`@1 GURALNIK (Jack M.)`
A14	`01`			`@1 Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging @2 Bethesda, Maryland @3 USA @Z 1 aut. @Z 2 aut. @Z 5 aut. @Z 7 aut.`
A14	`02`			`@1 South district Geriatric Physician, Ministry of Health @2 Beer-Sheva @3 ISR @Z 1 aut.`
A14	`03`			`@1 Johns Hopkins University School of Medicine @2 Baltimore, Maryland @3 USA @Z 3 aut.`
A14	`04`			`@1 Geriatric Rehabilitation Unit, Azienda Sanitaria Firenze @3 ITA @Z 4 aut.`
A14	`05`			`@1 The S. Daniel Abraham International Center for health and Nutrition, Ben-Gurion University of the Negev @2 Beer-Sheva @3 ISR @Z 5 aut.`
A14	`06`			`@1 Clinical Research Branch, National Institute on Aging @2 Baltimore, Maryland @3 USA @Z 6 aut.`
A20				`@1 1909-1915`
A21				`@1 2010`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20953 @5 354000194841700190`
A44				`@0 0000 @1 © 2010 INIST-CNRS. All rights reserved.`
A45				`@0 32 ref.`
A47	`01`	`1`		`@0 10-0446308`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 Parkinson's disease (PD) is a degenerative process affecting the striato nigral system (SN). Its etiology, although obscure, may involve oxidative damage. Selenium, an antioxidant, was shown to protect the SN in animal models. In the current study, we investigate the association between plasma selenium concentrations and the presence of "soft" neurological signs related to the SN. Plasma selenium concentration was assessed in participants of age ≥65 years in the InCHIANTI study, a population-based cohort study in Tuscany, Italy. PD was defined based on standard criteria. "Soft" neurological signs were ascertained by physical examination. A total of 1,012 participants were included. No association was found between the presence of PD and plasma selenium. There was, however, a strong association between plasma selenium and timed performance-based assessments. Lower levels of selenium were significantly associated with decreased performance in neurological tests of coordination among older adults. Prospective studies are needed to further investigate the effects of selenium on SN dysfunction.
C02	`01`	`X`		`@0 002B17`
C02	`02`	`X`		`@0 002B24D02`
C03	`01`	`X`	`FRE`	`@0 Maladie de Parkinson @2 NM @5 01`
C03	`01`	`X`	`ENG`	`@0 Parkinson disease @2 NM @5 01`
C03	`01`	`X`	`SPA`	`@0 Parkinson enfermedad @2 NM @5 01`
C03	`02`	`X`	`FRE`	`@0 Pathologie du système nerveux @5 02`
C03	`02`	`X`	`ENG`	`@0 Nervous system diseases @5 02`
C03	`02`	`X`	`SPA`	`@0 Sistema nervioso patología @5 02`
C03	`03`	`X`	`FRE`	`@0 Sélénium @2 NC @5 09`
C03	`03`	`X`	`ENG`	`@0 Selenium @2 NC @5 09`
C03	`03`	`X`	`SPA`	`@0 Selenio @2 NC @5 09`
C03	`04`	`X`	`FRE`	`@0 Performance @5 10`
C03	`04`	`X`	`ENG`	`@0 Performance @5 10`
C03	`04`	`X`	`SPA`	`@0 Rendimiento @5 10`
C03	`05`	`X`	`FRE`	`@0 Coordination @5 11`
C03	`05`	`X`	`ENG`	`@0 Coordination @5 11`
C03	`05`	`X`	`SPA`	`@0 Coordinación @5 11`
C03	`06`	`X`	`FRE`	`@0 Vitesse déplacement @5 12`
C03	`06`	`X`	`ENG`	`@0 Speed @5 12`
C03	`06`	`X`	`SPA`	`@0 Velocidad desplazamiento @5 12`
C03	`07`	`X`	`FRE`	`@0 Antioxydant @5 13`
C03	`07`	`X`	`ENG`	`@0 Antioxidant @5 13`
C03	`07`	`X`	`SPA`	`@0 Antioxidante @5 13`
C03	`08`	`X`	`FRE`	`@0 Personne âgée @5 14`
C03	`08`	`X`	`ENG`	`@0 Elderly @5 14`
C03	`08`	`X`	`SPA`	`@0 Anciano @5 14`
C07	`01`	`X`	`FRE`	`@0 Homme`
C07	`01`	`X`	`ENG`	`@0 Human`
C07	`01`	`X`	`SPA`	`@0 Hombre`
C07	`02`	`X`	`FRE`	`@0 Pathologie de l'encéphale @5 37`
C07	`02`	`X`	`ENG`	`@0 Cerebral disorder @5 37`
C07	`02`	`X`	`SPA`	`@0 Encéfalo patología @5 37`
C07	`03`	`X`	`FRE`	`@0 Syndrome extrapyramidal @5 38`
C07	`03`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 38`
C07	`03`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 38`
C07	`04`	`X`	`FRE`	`@0 Maladie dégénérative @5 39`
C07	`04`	`X`	`ENG`	`@0 Degenerative disease @5 39`
C07	`04`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 39`
C07	`05`	`X`	`FRE`	`@0 Pathologie du système nerveux central @5 40`
C07	`05`	`X`	`ENG`	`@0 Central nervous system disease @5 40`
C07	`05`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 40`
N21				`@1 291`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 10-0446308 INIST
ET :	Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed
AU :	SHAHAR (Avner); PATEL (Kushang V.); SEMBA (Richard D.); BANDINELLI (Stefania); SHAHAR (Danit R.); FERRUCCI (Louigi); GURALNIK (Jack M.)
AF :	Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging/Bethesda, Maryland/Etats-Unis (1 aut., 2 aut., 5 aut., 7 aut.); South district Geriatric Physician, Ministry of Health/Beer-Sheva/Israël (1 aut.); Johns Hopkins University School of Medicine/Baltimore, Maryland/Etats-Unis (3 aut.); Geriatric Rehabilitation Unit, Azienda Sanitaria Firenze/Italie (4 aut.); The S. Daniel Abraham International Center for health and Nutrition, Ben-Gurion University of the Negev/Beer-Sheva/Israël (5 aut.); Clinical Research Branch, National Institute on Aging/Baltimore, Maryland/Etats-Unis (6 aut.)
DT :	Publication en série; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 12; Pp. 1909-1915; Bibl. 32 ref.
LA :	Anglais
EA :	Parkinson's disease (PD) is a degenerative process affecting the striato nigral system (SN). Its etiology, although obscure, may involve oxidative damage. Selenium, an antioxidant, was shown to protect the SN in animal models. In the current study, we investigate the association between plasma selenium concentrations and the presence of "soft" neurological signs related to the SN. Plasma selenium concentration was assessed in participants of age ≥65 years in the InCHIANTI study, a population-based cohort study in Tuscany, Italy. PD was defined based on standard criteria. "Soft" neurological signs were ascertained by physical examination. A total of 1,012 participants were included. No association was found between the presence of PD and plasma selenium. There was, however, a strong association between plasma selenium and timed performance-based assessments. Lower levels of selenium were significantly associated with decreased performance in neurological tests of coordination among older adults. Prospective studies are needed to further investigate the effects of selenium on SN dysfunction.
CC :	002B17; 002B24D02
FD :	Maladie de Parkinson; Pathologie du système nerveux; Sélénium; Performance; Coordination; Vitesse déplacement; Antioxydant; Personne âgée
FG :	Homme; Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central
ED :	Parkinson disease; Nervous system diseases; Selenium; Performance; Coordination; Speed; Antioxidant; Elderly
EG :	Human; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD :	Parkinson enfermedad; Sistema nervioso patología; Selenio; Rendimiento; Coordinación; Velocidad desplazamiento; Antioxidante; Anciano
LO :	INIST-20953.354000194841700190
ID :	10-0446308

Links to Exploration step

Pascal:10-0446308

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed</title>
<author><name sortKey="Shahar, Avner" sort="Shahar, Avner" uniqKey="Shahar A" first="Avner" last="Shahar">Avner Shahar</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>South district Geriatric Physician, Ministry of Health</s1>
<s2>Beer-Sheva</s2>
<s3>ISR</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Patel, Kushang V" sort="Patel, Kushang V" uniqKey="Patel K" first="Kushang V." last="Patel">Kushang V. Patel</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Semba, Richard D" sort="Semba, Richard D" uniqKey="Semba R" first="Richard D." last="Semba">Richard D. Semba</name>
<affiliation><inist:fA14 i1="03"><s1>Johns Hopkins University School of Medicine</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name>
<affiliation><inist:fA14 i1="04"><s1>Geriatric Rehabilitation Unit, Azienda Sanitaria Firenze</s1>
<s3>ITA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Shahar, Danit R" sort="Shahar, Danit R" uniqKey="Shahar D" first="Danit R." last="Shahar">Danit R. Shahar</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="05"><s1>The S. Daniel Abraham International Center for health and Nutrition, Ben-Gurion University of the Negev</s1>
<s2>Beer-Sheva</s2>
<s3>ISR</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Ferrucci, Louigi" sort="Ferrucci, Louigi" uniqKey="Ferrucci L" first="Louigi" last="Ferrucci">Louigi Ferrucci</name>
<affiliation><inist:fA14 i1="06"><s1>Clinical Research Branch, National Institute on Aging</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Guralnik, Jack M" sort="Guralnik, Jack M" uniqKey="Guralnik J" first="Jack M." last="Guralnik">Jack M. Guralnik</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">10-0446308</idno>
<date when="2010">2010</date>
<idno type="stanalyst">PASCAL 10-0446308 INIST</idno>
<idno type="RBID">Pascal:10-0446308</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000922</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed</title>
<author><name sortKey="Shahar, Avner" sort="Shahar, Avner" uniqKey="Shahar A" first="Avner" last="Shahar">Avner Shahar</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="02"><s1>South district Geriatric Physician, Ministry of Health</s1>
<s2>Beer-Sheva</s2>
<s3>ISR</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Patel, Kushang V" sort="Patel, Kushang V" uniqKey="Patel K" first="Kushang V." last="Patel">Kushang V. Patel</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Semba, Richard D" sort="Semba, Richard D" uniqKey="Semba R" first="Richard D." last="Semba">Richard D. Semba</name>
<affiliation><inist:fA14 i1="03"><s1>Johns Hopkins University School of Medicine</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Bandinelli, Stefania" sort="Bandinelli, Stefania" uniqKey="Bandinelli S" first="Stefania" last="Bandinelli">Stefania Bandinelli</name>
<affiliation><inist:fA14 i1="04"><s1>Geriatric Rehabilitation Unit, Azienda Sanitaria Firenze</s1>
<s3>ITA</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Shahar, Danit R" sort="Shahar, Danit R" uniqKey="Shahar D" first="Danit R." last="Shahar">Danit R. Shahar</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
<affiliation><inist:fA14 i1="05"><s1>The S. Daniel Abraham International Center for health and Nutrition, Ben-Gurion University of the Negev</s1>
<s2>Beer-Sheva</s2>
<s3>ISR</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Ferrucci, Louigi" sort="Ferrucci, Louigi" uniqKey="Ferrucci L" first="Louigi" last="Ferrucci">Louigi Ferrucci</name>
<affiliation><inist:fA14 i1="06"><s1>Clinical Research Branch, National Institute on Aging</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Guralnik, Jack M" sort="Guralnik, Jack M" uniqKey="Guralnik J" first="Jack M." last="Guralnik">Jack M. Guralnik</name>
<affiliation><inist:fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2010">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antioxidant</term>
<term>Coordination</term>
<term>Elderly</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Performance</term>
<term>Selenium</term>
<term>Speed</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term>
<term>Pathologie du   système nerveux</term>
<term>Sélénium</term>
<term>Performance</term>
<term>Coordination</term>
<term>Vitesse déplacement</term>
<term>Antioxydant</term>
<term>Personne âgée</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Parkinson's disease (PD) is a degenerative process affecting the striato nigral system (SN). Its etiology, although obscure, may involve oxidative damage. Selenium, an antioxidant, was shown to protect the SN in animal models. In the current study, we investigate the association between plasma selenium concentrations and the presence of "soft" neurological signs related to the SN. Plasma selenium concentration was assessed in participants of age ≥65 years in the InCHIANTI study, a population-based cohort study in Tuscany, Italy. PD was defined based on standard criteria. "Soft" neurological signs were ascertained by physical examination. A total of 1,012 participants were included. No association was found between the presence of PD and plasma selenium. There was, however, a strong association between plasma selenium and timed performance-based assessments. Lower levels of selenium were significantly associated with decreased performance in neurological tests of coordination among older adults. Prospective studies are needed to further investigate the effects of selenium on SN dysfunction.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0>
</fA01>
<fA03 i2="1"><s0>Mov. disord.</s0>
</fA03>
<fA05><s2>25</s2>
</fA05>
<fA06><s2>12</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>SHAHAR (Avner)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>PATEL (Kushang V.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>SEMBA (Richard D.)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>BANDINELLI (Stefania)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>SHAHAR (Danit R.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>FERRUCCI (Louigi)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>GURALNIK (Jack M.)</s1>
</fA11>
<fA14 i1="01"><s1>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging</s1>
<s2>Bethesda, Maryland</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>South district Geriatric Physician, Ministry of Health</s1>
<s2>Beer-Sheva</s2>
<s3>ISR</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Johns Hopkins University School of Medicine</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Geriatric Rehabilitation Unit, Azienda Sanitaria Firenze</s1>
<s3>ITA</s3>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>The S. Daniel Abraham International Center for health and Nutrition, Ben-Gurion University of the Negev</s1>
<s2>Beer-Sheva</s2>
<s3>ISR</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="06"><s1>Clinical Research Branch, National Institute on Aging</s1>
<s2>Baltimore, Maryland</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
</fA14>
<fA20><s1>1909-1915</s1>
</fA20>
<fA21><s1>2010</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>20953</s2>
<s5>354000194841700190</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2010 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>32 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>10-0446308</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Movement disorders</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Parkinson's disease (PD) is a degenerative process affecting the striato nigral system (SN). Its etiology, although obscure, may involve oxidative damage. Selenium, an antioxidant, was shown to protect the SN in animal models. In the current study, we investigate the association between plasma selenium concentrations and the presence of "soft" neurological signs related to the SN. Plasma selenium concentration was assessed in participants of age ≥65 years in the InCHIANTI study, a population-based cohort study in Tuscany, Italy. PD was defined based on standard criteria. "Soft" neurological signs were ascertained by physical examination. A total of 1,012 participants were included. No association was found between the presence of PD and plasma selenium. There was, however, a strong association between plasma selenium and timed performance-based assessments. Lower levels of selenium were significantly associated with decreased performance in neurological tests of coordination among older adults. Prospective studies are needed to further investigate the effects of selenium on SN dysfunction.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B24D02</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Maladie de Parkinson</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Parkinson disease</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Parkinson enfermedad</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Pathologie du   système nerveux</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Sélénium</s0>
<s2>NC</s2>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Selenium</s0>
<s2>NC</s2>
<s5>09</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Selenio</s0>
<s2>NC</s2>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Performance</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Performance</s0>
<s5>10</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Rendimiento</s0>
<s5>10</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Coordination</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Coordination</s0>
<s5>11</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Coordinación</s0>
<s5>11</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Vitesse déplacement</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Speed</s0>
<s5>12</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Velocidad desplazamiento</s0>
<s5>12</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Antioxydant</s0>
<s5>13</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Antioxidant</s0>
<s5>13</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Antioxidante</s0>
<s5>13</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Personne âgée</s0>
<s5>14</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Elderly</s0>
<s5>14</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Anciano</s0>
<s5>14</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Homme</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Human</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Hombre</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Pathologie de l'encéphale</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Syndrome extrapyramidal</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Pathologie du   système nerveux central</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fN21><s1>291</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 10-0446308 INIST</NO>
<ET>Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed</ET>
<AU>SHAHAR (Avner); PATEL (Kushang V.); SEMBA (Richard D.); BANDINELLI (Stefania); SHAHAR (Danit R.); FERRUCCI (Louigi); GURALNIK (Jack M.)</AU>
<AF>Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging/Bethesda, Maryland/Etats-Unis (1 aut., 2 aut., 5 aut., 7 aut.); South district Geriatric Physician, Ministry of Health/Beer-Sheva/Israël (1 aut.); Johns Hopkins University School of Medicine/Baltimore, Maryland/Etats-Unis (3 aut.); Geriatric Rehabilitation Unit, Azienda Sanitaria Firenze/Italie (4 aut.); The S. Daniel Abraham International Center for health and Nutrition, Ben-Gurion University of the Negev/Beer-Sheva/Israël (5 aut.); Clinical Research Branch, National Institute on Aging/Baltimore, Maryland/Etats-Unis (6 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 12; Pp. 1909-1915; Bibl. 32 ref.</SO>
<LA>Anglais</LA>
<EA>Parkinson's disease (PD) is a degenerative process affecting the striato nigral system (SN). Its etiology, although obscure, may involve oxidative damage. Selenium, an antioxidant, was shown to protect the SN in animal models. In the current study, we investigate the association between plasma selenium concentrations and the presence of "soft" neurological signs related to the SN. Plasma selenium concentration was assessed in participants of age ≥65 years in the InCHIANTI study, a population-based cohort study in Tuscany, Italy. PD was defined based on standard criteria. "Soft" neurological signs were ascertained by physical examination. A total of 1,012 participants were included. No association was found between the presence of PD and plasma selenium. There was, however, a strong association between plasma selenium and timed performance-based assessments. Lower levels of selenium were significantly associated with decreased performance in neurological tests of coordination among older adults. Prospective studies are needed to further investigate the effects of selenium on SN dysfunction.</EA>
<CC>002B17; 002B24D02</CC>
<FD>Maladie de Parkinson; Pathologie du   système nerveux; Sélénium; Performance; Coordination; Vitesse déplacement; Antioxydant; Personne âgée</FD>
<FG>Homme; Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central</FG>
<ED>Parkinson disease; Nervous system diseases; Selenium; Performance; Coordination; Speed; Antioxidant; Elderly</ED>
<EG>Human; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease</EG>
<SD>Parkinson enfermedad; Sistema nervioso patología; Selenio; Rendimiento; Coordinación; Velocidad desplazamiento; Antioxidante; Anciano</SD>
<LO>INIST-20953.354000194841700190</LO>
<ID>10-0446308</ID>
</server>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PascalFrancis/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000922 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 000922 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    PascalFrancis
   |étape=   Corpus
   |type=    RBID
   |clé=     Pascal:10-0446308
   |texte=   Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed
}}

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed

Plasma Selenium is Positively Related to Performance in Neurological Tasks Assessing Coordination and Motor Speed

Source :

Descripteurs français

English descriptors

Abstract

Notice en format standard (ISO 2709)

Format Inist (serveur)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri