Movement Disorders (revue)

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Tourette's Syndrome in Adults

Identifieur interne : 000873 ( PascalFrancis/Corpus ); précédent : 000872; suivant : 000874

Tourette's Syndrome in Adults

Auteurs : Joseph Jankovic ; Rose Gelineau-Kattner ; Anthony Davidson

Source :

RBID : Pascal:10-0474358

Descripteurs français

English descriptors

Abstract

Tourette's syndrome (TS) is defined as motor and phonic tics starting betore age 18 years, and theretore most studies have focused on childhood TS, whereas the disorder in adults has not been well characterized. We reviewed medical records of all new TS patients referred to our Movement Disorders Clinic over the past 5 years, 19 years or older on initial evaluation and compared them with 100 TS patients 18 years or younger. The mean age at initial visit of 43 adult TS patients was 58.8 ± 6.7 years, whereas the mean age at initial visit of children with TS was 12.9 ± 2.0 years. Of the adult TS patients, 35 (8 1 .4%) had a history of tics with onset before the age of 18 years (mean age at onset: 8.5 ± 3.4 years), with 8 (18.6%) reporting first occurrence of tics after the age of 18 years (mean age at onset: 37.8 ± 13.2 years). Only two (4.7%) patients reported tic onset after the age of 50 years. Adult patients with TS had significantly more facial and truncal tics, and a greater prevalence of substance abuse and mood disorders, but fewer phonic tics, and lower rates of attention-deficit hyperactivity disorder and oppositional behavior than children with TS. Adult TS largely represents reemergence or exacerbation of childhood-onset TS. During the course of TS, phonic and complex motor tics, self-injurious behaviors, and attention-deficit hyperactivity disorder tend to improve, but facial, neck, and trunk tics dominate the adult TS phenotype. In addition, adults with TS are more likely to exhibit substance abuse and mood disorders compared with children with TS.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
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A03   1    @0 Mov. disord.
A05       @2 25
A06       @2 13
A08 01  1  ENG  @1 Tourette's Syndrome in Adults
A11 01  1    @1 JANKOVIC (Joseph)
A11 02  1    @1 GELINEAU-KATTNER (Rose)
A11 03  1    @1 DAVIDSON (Anthony)
A14 01      @1 Parkinson Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine @2 Houston, Texas @3 USA @Z 1 aut. @Z 2 aut. @Z 3 aut.
A20       @1 2171-2175
A21       @1 2010
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C01 01    ENG  @0 Tourette's syndrome (TS) is defined as motor and phonic tics starting betore age 18 years, and theretore most studies have focused on childhood TS, whereas the disorder in adults has not been well characterized. We reviewed medical records of all new TS patients referred to our Movement Disorders Clinic over the past 5 years, 19 years or older on initial evaluation and compared them with 100 TS patients 18 years or younger. The mean age at initial visit of 43 adult TS patients was 58.8 ± 6.7 years, whereas the mean age at initial visit of children with TS was 12.9 ± 2.0 years. Of the adult TS patients, 35 (8 1 .4%) had a history of tics with onset before the age of 18 years (mean age at onset: 8.5 ± 3.4 years), with 8 (18.6%) reporting first occurrence of tics after the age of 18 years (mean age at onset: 37.8 ± 13.2 years). Only two (4.7%) patients reported tic onset after the age of 50 years. Adult patients with TS had significantly more facial and truncal tics, and a greater prevalence of substance abuse and mood disorders, but fewer phonic tics, and lower rates of attention-deficit hyperactivity disorder and oppositional behavior than children with TS. Adult TS largely represents reemergence or exacerbation of childhood-onset TS. During the course of TS, phonic and complex motor tics, self-injurious behaviors, and attention-deficit hyperactivity disorder tend to improve, but facial, neck, and trunk tics dominate the adult TS phenotype. In addition, adults with TS are more likely to exhibit substance abuse and mood disorders compared with children with TS.
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C03 01  X  ENG  @0 Gilles de la Tourette syndrome @5 01
C03 01  X  SPA  @0 Gilles de la Tourette síndrome @5 01
C03 02  X  FRE  @0 Tic @5 02
C03 02  X  ENG  @0 Tic @5 02
C03 02  X  SPA  @0 Tic @5 02
C03 03  X  FRE  @0 Pathologie du système nerveux @5 03
C03 03  X  ENG  @0 Nervous system diseases @5 03
C03 03  X  SPA  @0 Sistema nervioso patología @5 03
C07 01  X  FRE  @0 Pathologie de l'encéphale @5 37
C07 01  X  ENG  @0 Cerebral disorder @5 37
C07 01  X  SPA  @0 Encéfalo patología @5 37
C07 02  X  FRE  @0 Maladie dégénérative @5 38
C07 02  X  ENG  @0 Degenerative disease @5 38
C07 02  X  SPA  @0 Enfermedad degenerativa @5 38
C07 03  X  FRE  @0 Pathologie du système nerveux central @5 39
C07 03  X  ENG  @0 Central nervous system disease @5 39
C07 03  X  SPA  @0 Sistema nervosio central patología @5 39
C07 04  X  FRE  @0 Mouvement involontaire @5 41
C07 04  X  ENG  @0 Involuntary movement @5 41
C07 04  X  SPA  @0 Movimiento involuntario @5 41
C07 05  X  FRE  @0 Trouble neurologique @5 42
C07 05  X  ENG  @0 Neurological disorder @5 42
C07 05  X  SPA  @0 Trastorno neurológico @5 42
N21       @1 312
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 10-0474358 INIST
ET : Tourette's Syndrome in Adults
AU : JANKOVIC (Joseph); GELINEAU-KATTNER (Rose); DAVIDSON (Anthony)
AF : Parkinson Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine/Houston, Texas/Etats-Unis (1 aut., 2 aut., 3 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2010; Vol. 25; No. 13; Pp. 2171-2175; Bibl. 22 ref.
LA : Anglais
EA : Tourette's syndrome (TS) is defined as motor and phonic tics starting betore age 18 years, and theretore most studies have focused on childhood TS, whereas the disorder in adults has not been well characterized. We reviewed medical records of all new TS patients referred to our Movement Disorders Clinic over the past 5 years, 19 years or older on initial evaluation and compared them with 100 TS patients 18 years or younger. The mean age at initial visit of 43 adult TS patients was 58.8 ± 6.7 years, whereas the mean age at initial visit of children with TS was 12.9 ± 2.0 years. Of the adult TS patients, 35 (8 1 .4%) had a history of tics with onset before the age of 18 years (mean age at onset: 8.5 ± 3.4 years), with 8 (18.6%) reporting first occurrence of tics after the age of 18 years (mean age at onset: 37.8 ± 13.2 years). Only two (4.7%) patients reported tic onset after the age of 50 years. Adult patients with TS had significantly more facial and truncal tics, and a greater prevalence of substance abuse and mood disorders, but fewer phonic tics, and lower rates of attention-deficit hyperactivity disorder and oppositional behavior than children with TS. Adult TS largely represents reemergence or exacerbation of childhood-onset TS. During the course of TS, phonic and complex motor tics, self-injurious behaviors, and attention-deficit hyperactivity disorder tend to improve, but facial, neck, and trunk tics dominate the adult TS phenotype. In addition, adults with TS are more likely to exhibit substance abuse and mood disorders compared with children with TS.
CC : 002B17; 002B17D
FD : Syndrome de Gilles de la Tourette; Tic; Pathologie du système nerveux
FG : Pathologie de l'encéphale; Maladie dégénérative; Pathologie du système nerveux central; Mouvement involontaire; Trouble neurologique
ED : Gilles de la Tourette syndrome; Tic; Nervous system diseases
EG : Cerebral disorder; Degenerative disease; Central nervous system disease; Involuntary movement; Neurological disorder
SD : Gilles de la Tourette síndrome; Tic; Sistema nervioso patología
LO : INIST-20953.354000193258110230
ID : 10-0474358

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Pascal:10-0474358

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<ED>Gilles de la Tourette syndrome; Tic; Nervous system diseases</ED>
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<SD>Gilles de la Tourette síndrome; Tic; Sistema nervioso patología</SD>
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<ID>10-0474358</ID>
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