Revisiting the Relationship Between Essential Tremor and Parkinson's Disease
Identifieur interne : 000690 ( PascalFrancis/Corpus ); précédent : 000689; suivant : 000691Revisiting the Relationship Between Essential Tremor and Parkinson's Disease
Auteurs : R. Fekete ; J. JankovicSource :
- Movement disorders [ 0885-3185 ] ; 2011.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Background: The relationship between essential tremor and Parkinson's disease has been a subject of reviews and debates for long time, but there is now growing evidence that the two common movement disorders are pathogenically related, at least in some patient populations. Methods: PubMed as well as authors' own files were searched for relevant keywords regarding overlap between the disorders in clinical features as well as on epidemiologic, genetic, imaging, and pathological studies. Results: New findings in each of these categories are critically reviewed and placed in the context of previously published data. DISCUSSION: Although we believe that there is compelling evidence for the notion that some patients with "pure" ET evolve into PD, the biologic nature of the association is not well understood. Furthermore, it is not clear what factors predict which ET patients later develop PD and whether patients with PD are more likely to develop ET. Further epidemiologic, clinical, genetic, imaging, and pathological studies are needed to better understand this mixed, ET-PD phenotype.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 11-0211275 INIST |
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ET : | Revisiting the Relationship Between Essential Tremor and Parkinson's Disease |
AU : | FEKETE (R.); JANKOVIC (J.) |
AF : | Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine/Houston, Texas/Etats-Unis (1 aut., 2 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2011; Vol. 26; No. 3; Pp. 391-398; Bibl. 74 ref. |
LA : | Anglais |
EA : | Background: The relationship between essential tremor and Parkinson's disease has been a subject of reviews and debates for long time, but there is now growing evidence that the two common movement disorders are pathogenically related, at least in some patient populations. Methods: PubMed as well as authors' own files were searched for relevant keywords regarding overlap between the disorders in clinical features as well as on epidemiologic, genetic, imaging, and pathological studies. Results: New findings in each of these categories are critically reviewed and placed in the context of previously published data. DISCUSSION: Although we believe that there is compelling evidence for the notion that some patients with "pure" ET evolve into PD, the biologic nature of the association is not well understood. Furthermore, it is not clear what factors predict which ET patients later develop PD and whether patients with PD are more likely to develop ET. Further epidemiologic, clinical, genetic, imaging, and pathological studies are needed to better understand this mixed, ET-PD phenotype. |
CC : | 002B17; 002B17G |
FD : | Tremblement; Maladie de Parkinson; Pathologie du système nerveux; Cervelet; Corps Lewy |
FG : | Mouvement involontaire; Trouble neurologique; Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Encéphale; Système nerveux central |
ED : | Tremor; Parkinson disease; Nervous system diseases; Cerebellum; Lewy body |
EG : | Involuntary movement; Neurological disorder; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Encephalon; Central nervous system |
SD : | Temblor; Parkinson enfermedad; Sistema nervioso patología; Cerebelo; Cuerpo Lewy |
LO : | INIST-20953.354000190875360040 |
ID : | 11-0211275 |
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Pascal:11-0211275Le document en format XML
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<front><div type="abstract" xml:lang="en">Background: The relationship between essential tremor and Parkinson's disease has been a subject of reviews and debates for long time, but there is now growing evidence that the two common movement disorders are pathogenically related, at least in some patient populations. Methods: PubMed as well as authors' own files were searched for relevant keywords regarding overlap between the disorders in clinical features as well as on epidemiologic, genetic, imaging, and pathological studies. Results: New findings in each of these categories are critically reviewed and placed in the context of previously published data. DISCUSSION: Although we believe that there is compelling evidence for the notion that some patients with "pure" ET evolve into PD, the biologic nature of the association is not well understood. Furthermore, it is not clear what factors predict which ET patients later develop PD and whether patients with PD are more likely to develop ET. Further epidemiologic, clinical, genetic, imaging, and pathological studies are needed to better understand this mixed, ET-PD phenotype.</div>
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<ET>Revisiting the Relationship Between Essential Tremor and Parkinson's Disease</ET>
<AU>FEKETE (R.); JANKOVIC (J.)</AU>
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<DT>Publication en série; Niveau analytique</DT>
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<LA>Anglais</LA>
<EA>Background: The relationship between essential tremor and Parkinson's disease has been a subject of reviews and debates for long time, but there is now growing evidence that the two common movement disorders are pathogenically related, at least in some patient populations. Methods: PubMed as well as authors' own files were searched for relevant keywords regarding overlap between the disorders in clinical features as well as on epidemiologic, genetic, imaging, and pathological studies. Results: New findings in each of these categories are critically reviewed and placed in the context of previously published data. DISCUSSION: Although we believe that there is compelling evidence for the notion that some patients with "pure" ET evolve into PD, the biologic nature of the association is not well understood. Furthermore, it is not clear what factors predict which ET patients later develop PD and whether patients with PD are more likely to develop ET. Further epidemiologic, clinical, genetic, imaging, and pathological studies are needed to better understand this mixed, ET-PD phenotype.</EA>
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