Phenotypic Spectrum of Musician's Dystonia: A Task-Specific Disorder?
Identifieur interne : 000660 ( PascalFrancis/Corpus ); précédent : 000659; suivant : 000661Phenotypic Spectrum of Musician's Dystonia: A Task-Specific Disorder?
Auteurs : Alexander Schmidt ; Hans-Christian Jabusch ; Eckart Altenmüller ; Leonie Enders ; Rachel Saunders-Pullman ; Susan B. Bressman ; Alexander Munchau ; Christine Klein ; Johann HagenahSource :
- Movement disorders [ 0885-3185 ] ; 2011.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background: Musician's dystonia (MD) is traditionally considered a sporadic and task-specific movement disorder. Methods: The phenotypic spectrum of the disorder was studied in 116 patients suffering from MD including videotaping. Results: Based on the movement disorders observed, we categorized our patients into two different groups: (i) 65 patients with isolated MD, that is only present when playing the instrument and (ii) 51 patients with MD and one or more additional features of primary dystonia independent of MD (complex MD). Patients with a positive family history of movement disorders had an increased risk to develop complex MD [odds ratio = 4.80; 95% confidence interval: 1.94-11.92; P = 0.001]. Discussion: In previous studies, we recently identified 22 relatives with different types of movement disorders in the families of 28 MD patients. Taken together, our results further support a genetic contribution to MD with a broad individual and familial phenotypic spectrum consisting of MD, other dystonias and even other, non-dystonic movement disorders.
Notice en format standard (ISO 2709)
Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 11-0211322 INIST |
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ET : | Phenotypic Spectrum of Musician's Dystonia: A Task-Specific Disorder? |
AU : | SCHMIDT (Alexander); JABUSCH (Hans-Christian); ALTENMÜLLER (Eckart); ENDERS (Leonie); SAUNDERS-PULLMAN (Rachel); BRESSMAN (Susan B.); MUNCHAU (Alexander); KLEIN (Christine); HAGENAH (Johann) |
AF : | Section of Clinical and Molecular Neurogenetics, University of Lüebeck/Lübeck/Allemagne (1 aut., 8 aut., 9 aut.); Department of Neurology, University of Lüebeck/Lübeck/Allemagne (1 aut., 8 aut., 9 aut.); Institute of Music Physiology and Musicians' Medicine, Hanover University of Music and Drama/Hanover/Allemagne (1 aut., 2 aut., 3 aut., 4 aut.); Institute of Musicians' Medicine, Dresden University of Music "Carl Maria von Weber"/Dresden/Allemagne (2 aut.); Department of Neurology, Albert Einstein College of Medicine/Bronx, New York/Etats-Unis (5 aut., 6 aut.); Department of Neurology, Beth Israel Medical Center, New York/New York/Etats-Unis (5 aut., 6 aut.); Department of Neurology, University Medical Center Hamburg-Eppendorf/Hamburg/Allemagne (7 aut.) |
DT : | Publication en série; Courte communication, note brève; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2011; Vol. 26; No. 3; Pp. 546-549; Bibl. 8 ref. |
LA : | Anglais |
EA : | Background: Musician's dystonia (MD) is traditionally considered a sporadic and task-specific movement disorder. Methods: The phenotypic spectrum of the disorder was studied in 116 patients suffering from MD including videotaping. Results: Based on the movement disorders observed, we categorized our patients into two different groups: (i) 65 patients with isolated MD, that is only present when playing the instrument and (ii) 51 patients with MD and one or more additional features of primary dystonia independent of MD (complex MD). Patients with a positive family history of movement disorders had an increased risk to develop complex MD [odds ratio = 4.80; 95% confidence interval: 1.94-11.92; P = 0.001]. Discussion: In previous studies, we recently identified 22 relatives with different types of movement disorders in the families of 28 MD patients. Taken together, our results further support a genetic contribution to MD with a broad individual and familial phenotypic spectrum consisting of MD, other dystonias and even other, non-dystonic movement disorders. |
CC : | 002B17; 002B17H |
FD : | Dystonie; Crampe écrivain; Pathologie du système nerveux; Musicien |
FG : | Syndrome extrapyramidal; Mouvement involontaire; Pathologie du muscle strié; Trouble neurologique; Pathologie de l'encéphale; Pathologie du système nerveux central |
ED : | Dystonia; Writer cramp; Nervous system diseases; Musician |
EG : | Extrapyramidal syndrome; Involuntary movement; Striated muscle disease; Neurological disorder; Cerebral disorder; Central nervous system disease |
SD : | Distonía; Calambre escribano; Sistema nervioso patología; Músico |
LO : | INIST-20953.354000190875360270 |
ID : | 11-0211322 |
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Pascal:11-0211322Le document en format XML
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<front><div type="abstract" xml:lang="en">Background: Musician's dystonia (MD) is traditionally considered a sporadic and task-specific movement disorder. Methods: The phenotypic spectrum of the disorder was studied in 116 patients suffering from MD including videotaping. Results: Based on the movement disorders observed, we categorized our patients into two different groups: (i) 65 patients with isolated MD, that is only present when playing the instrument and (ii) 51 patients with MD and one or more additional features of primary dystonia independent of MD (complex MD). Patients with a positive family history of movement disorders had an increased risk to develop complex MD [odds ratio = 4.80; 95% confidence interval: 1.94-11.92; P = 0.001]. Discussion: In previous studies, we recently identified 22 relatives with different types of movement disorders in the families of 28 MD patients. Taken together, our results further support a genetic contribution to MD with a broad individual and familial phenotypic spectrum consisting of MD, other dystonias and even other, non-dystonic movement disorders.</div>
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</fA61>
<fA64 i1="01" i2="1"><s0>Movement disorders</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Background: Musician's dystonia (MD) is traditionally considered a sporadic and task-specific movement disorder. Methods: The phenotypic spectrum of the disorder was studied in 116 patients suffering from MD including videotaping. Results: Based on the movement disorders observed, we categorized our patients into two different groups: (i) 65 patients with isolated MD, that is only present when playing the instrument and (ii) 51 patients with MD and one or more additional features of primary dystonia independent of MD (complex MD). Patients with a positive family history of movement disorders had an increased risk to develop complex MD [odds ratio = 4.80; 95% confidence interval: 1.94-11.92; P = 0.001]. Discussion: In previous studies, we recently identified 22 relatives with different types of movement disorders in the families of 28 MD patients. Taken together, our results further support a genetic contribution to MD with a broad individual and familial phenotypic spectrum consisting of MD, other dystonias and even other, non-dystonic movement disorders.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B17H</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Dystonie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Dystonia</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Distonía</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Crampe écrivain</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Writer cramp</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Calambre escribano</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Pathologie du système nerveux</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Musicien</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Musician</s0>
<s5>09</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Músico</s0>
<s5>09</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Syndrome extrapyramidal</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Mouvement involontaire</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Involuntary movement</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Movimiento involuntario</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Pathologie du muscle strié</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Striated muscle disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Músculo estriado patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Trouble neurologique</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Neurological disorder</s0>
<s5>41</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Trastorno neurológico</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Pathologie de l'encéphale</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>42</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Pathologie du système nerveux central</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>43</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>43</s5>
</fC07>
<fN21><s1>143</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 11-0211322 INIST</NO>
<ET>Phenotypic Spectrum of Musician's Dystonia: A Task-Specific Disorder?</ET>
<AU>SCHMIDT (Alexander); JABUSCH (Hans-Christian); ALTENMÜLLER (Eckart); ENDERS (Leonie); SAUNDERS-PULLMAN (Rachel); BRESSMAN (Susan B.); MUNCHAU (Alexander); KLEIN (Christine); HAGENAH (Johann)</AU>
<AF>Section of Clinical and Molecular Neurogenetics, University of Lüebeck/Lübeck/Allemagne (1 aut., 8 aut., 9 aut.); Department of Neurology, University of Lüebeck/Lübeck/Allemagne (1 aut., 8 aut., 9 aut.); Institute of Music Physiology and Musicians' Medicine, Hanover University of Music and Drama/Hanover/Allemagne (1 aut., 2 aut., 3 aut., 4 aut.); Institute of Musicians' Medicine, Dresden University of Music "Carl Maria von Weber"/Dresden/Allemagne (2 aut.); Department of Neurology, Albert Einstein College of Medicine/Bronx, New York/Etats-Unis (5 aut., 6 aut.); Department of Neurology, Beth Israel Medical Center, New York/New York/Etats-Unis (5 aut., 6 aut.); Department of Neurology, University Medical Center Hamburg-Eppendorf/Hamburg/Allemagne (7 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2011; Vol. 26; No. 3; Pp. 546-549; Bibl. 8 ref.</SO>
<LA>Anglais</LA>
<EA>Background: Musician's dystonia (MD) is traditionally considered a sporadic and task-specific movement disorder. Methods: The phenotypic spectrum of the disorder was studied in 116 patients suffering from MD including videotaping. Results: Based on the movement disorders observed, we categorized our patients into two different groups: (i) 65 patients with isolated MD, that is only present when playing the instrument and (ii) 51 patients with MD and one or more additional features of primary dystonia independent of MD (complex MD). Patients with a positive family history of movement disorders had an increased risk to develop complex MD [odds ratio = 4.80; 95% confidence interval: 1.94-11.92; P = 0.001]. Discussion: In previous studies, we recently identified 22 relatives with different types of movement disorders in the families of 28 MD patients. Taken together, our results further support a genetic contribution to MD with a broad individual and familial phenotypic spectrum consisting of MD, other dystonias and even other, non-dystonic movement disorders.</EA>
<CC>002B17; 002B17H</CC>
<FD>Dystonie; Crampe écrivain; Pathologie du système nerveux; Musicien</FD>
<FG>Syndrome extrapyramidal; Mouvement involontaire; Pathologie du muscle strié; Trouble neurologique; Pathologie de l'encéphale; Pathologie du système nerveux central</FG>
<ED>Dystonia; Writer cramp; Nervous system diseases; Musician</ED>
<EG>Extrapyramidal syndrome; Involuntary movement; Striated muscle disease; Neurological disorder; Cerebral disorder; Central nervous system disease</EG>
<SD>Distonía; Calambre escribano; Sistema nervioso patología; Músico</SD>
<LO>INIST-20953.354000190875360270</LO>
<ID>11-0211322</ID>
</server>
</inist>
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