MovDisordV3, PascalFrancis, Corpus, bibRecord, 000545

Decades of Delayed Diagnosis in 4 Levodopa-Responsive Young-Onset Monogenetic Parkinsonism Patients

Identifieur interne : 000545 ( PascalFrancis/Corpus ); précédent : 000544; suivant : 000546

Decades of Delayed Diagnosis in 4 Levodopa-Responsive Young-Onset Monogenetic Parkinsonism Patients

Auteurs : Helen Ling ; Mark Braschinsky ; Pille Taba ; Siiri-Merike Luus ; Karen Doherty ; Anna Hotter ; Werner Poewe ; Andrew J. Lees

Source :

Movement disorders [ 0885-3185 ] ; 2011.

RBID : Pascal:11-0321221

Descripteurs français

Pascal (Inist)
- Parkinsonisme, Conversion somatique, Syndrome de fatigue chronique, Pathologie du système nerveux, Diagnostic, Lévodopa, Homme, Parkine, Psychogène.

English descriptors

KwdEn :
- Chronic fatigue syndrome, Diagnosis, Human, Levodopa, Nervous system diseases, Parkin, Parkinsonism, Psychogenic, Somatic conversion.

Abstract

Background: We report 4 patients with young-onset monogenetic parkinsonism, each of whom was misdiagnosed with either a psychogenic movement disorder or chronic fatigue syndrome for 10 to 23 years after the onset of their first symptoms. Results: Once the diagnosis was eventually made, they all had a rapid and excellent response to levodopa, albeit with the early appearance of interdose dyskinesias in 3. Conclusions: We discuss possible reasons for the missed diagnosis despite the relentless progression of their motor handicap. DAT scanning supported the revised clinical diagnosis of parkinsonism.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A03		`1`		`@0 Mov. disord.`
A05				`@2 26`
A06				`@2 7`
A08	`01`	`1`	`ENG`	`@1 Decades of Delayed Diagnosis in 4 Levodopa-Responsive Young-Onset Monogenetic Parkinsonism Patients`
A11	`01`	`1`		`@1 LING (Helen)`
A11	`02`	`1`		`@1 BRASCHINSKY (Mark)`
A11	`03`	`1`		`@1 TABA (Pille)`
A11	`04`	`1`		`@1 LUUS (Siiri-Merike)`
A11	`05`	`1`		`@1 DOHERTY (Karen)`
A11	`06`	`1`		`@1 HOTTER (Anna)`
A11	`07`	`1`		`@1 POEWE (Werner)`
A11	`08`	`1`		`@1 LEES (Andrew J.)`
A14	`01`			`@1 Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London @2 London @3 GBR @Z 1 aut. @Z 5 aut. @Z 8 aut.`
A14	`02`			`@1 Queen Square Brain Bank for Neurological Disorders and Institute of Neurology, University College London @2 London @3 GBR @Z 1 aut. @Z 5 aut. @Z 8 aut.`
A14	`03`			`@1 Department of Neurology, University of Tartu @2 Tartu @3 EST @Z 2 aut. @Z 3 aut. @Z 4 aut.`
A14	`04`			`@1 Department of Neurology, University Hospital of Innsbruck @3 AUT @Z 6 aut. @Z 7 aut.`
A20				`@1 1337-1340`
A21				`@1 2011`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 20953 @5 354000190480410210`
A44				`@0 0000 @1 © 2011 INIST-CNRS. All rights reserved.`
A45				`@0 8 ref.`
A47	`01`	`1`		`@0 11-0321221`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Movement disorders`
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C01	`01`		`ENG`	@0 Background: We report 4 patients with young-onset monogenetic parkinsonism, each of whom was misdiagnosed with either a psychogenic movement disorder or chronic fatigue syndrome for 10 to 23 years after the onset of their first symptoms. Results: Once the diagnosis was eventually made, they all had a rapid and excellent response to levodopa, albeit with the early appearance of interdose dyskinesias in 3. Conclusions: We discuss possible reasons for the missed diagnosis despite the relentless progression of their motor handicap. DAT scanning supported the revised clinical diagnosis of parkinsonism.
C02	`01`	`X`		`@0 002B17`
C02	`02`	`X`		`@0 002B17F`
C03	`01`	`X`	`FRE`	`@0 Parkinsonisme @2 NM @5 01`
C03	`01`	`X`	`ENG`	`@0 Parkinsonism @2 NM @5 01`
C03	`01`	`X`	`SPA`	`@0 Parkinson síndrome @2 NM @5 01`
C03	`02`	`X`	`FRE`	`@0 Conversion somatique @5 02`
C03	`02`	`X`	`ENG`	`@0 Somatic conversion @5 02`
C03	`02`	`X`	`SPA`	`@0 Conversion somática @5 02`
C03	`03`	`X`	`FRE`	`@0 Syndrome de fatigue chronique @2 NM @5 03`
C03	`03`	`X`	`ENG`	`@0 Chronic fatigue syndrome @2 NM @5 03`
C03	`03`	`X`	`SPA`	`@0 Fatiga crónica síndrome @2 NM @5 03`
C03	`04`	`X`	`FRE`	`@0 Pathologie du système nerveux @5 04`
C03	`04`	`X`	`ENG`	`@0 Nervous system diseases @5 04`
C03	`04`	`X`	`SPA`	`@0 Sistema nervioso patología @5 04`
C03	`05`	`X`	`FRE`	`@0 Diagnostic @5 09`
C03	`05`	`X`	`ENG`	`@0 Diagnosis @5 09`
C03	`05`	`X`	`SPA`	`@0 Diagnóstico @5 09`
C03	`06`	`X`	`FRE`	`@0 Lévodopa @2 NK @2 FR @5 10`
C03	`06`	`X`	`ENG`	`@0 Levodopa @2 NK @2 FR @5 10`
C03	`06`	`X`	`SPA`	`@0 Levodopa @2 NK @2 FR @5 10`
C03	`07`	`X`	`FRE`	`@0 Homme @5 11`
C03	`07`	`X`	`ENG`	`@0 Human @5 11`
C03	`07`	`X`	`SPA`	`@0 Hombre @5 11`
C03	`08`	`X`	`FRE`	`@0 Parkine @5 12`
C03	`08`	`X`	`ENG`	`@0 Parkin @5 12`
C03	`08`	`X`	`SPA`	`@0 Parkin @5 12`
C03	`09`	`X`	`FRE`	`@0 Psychogène @5 13`
C03	`09`	`X`	`ENG`	`@0 Psychogenic @5 13`
C03	`09`	`X`	`SPA`	`@0 Psicógeno @5 13`
C07	`01`	`X`	`FRE`	`@0 Trouble somatoforme @2 NM @5 38`
C07	`01`	`X`	`ENG`	`@0 Somatoform disorder @2 NM @5 38`
C07	`01`	`X`	`SPA`	`@0 Trastorno somatoformo @2 NM @5 38`
N21				`@1 220`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 11-0321221 INIST
ET :	Decades of Delayed Diagnosis in 4 Levodopa-Responsive Young-Onset Monogenetic Parkinsonism Patients
AU :	LING (Helen); BRASCHINSKY (Mark); TABA (Pille); LUUS (Siiri-Merike); DOHERTY (Karen); HOTTER (Anna); POEWE (Werner); LEES (Andrew J.)
AF :	Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London/London/Royaume-Uni (1 aut., 5 aut., 8 aut.); Queen Square Brain Bank for Neurological Disorders and Institute of Neurology, University College London/London/Royaume-Uni (1 aut., 5 aut., 8 aut.); Department of Neurology, University of Tartu/Tartu/Estonie (2 aut., 3 aut., 4 aut.); Department of Neurology, University Hospital of Innsbruck/Autriche (6 aut., 7 aut.)
DT :	Publication en série; Niveau analytique
SO :	Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2011; Vol. 26; No. 7; Pp. 1337-1340; Bibl. 8 ref.
LA :	Anglais
EA :	Background: We report 4 patients with young-onset monogenetic parkinsonism, each of whom was misdiagnosed with either a psychogenic movement disorder or chronic fatigue syndrome for 10 to 23 years after the onset of their first symptoms. Results: Once the diagnosis was eventually made, they all had a rapid and excellent response to levodopa, albeit with the early appearance of interdose dyskinesias in 3. Conclusions: We discuss possible reasons for the missed diagnosis despite the relentless progression of their motor handicap. DAT scanning supported the revised clinical diagnosis of parkinsonism.
CC :	002B17; 002B17F
FD :	Parkinsonisme; Conversion somatique; Syndrome de fatigue chronique; Pathologie du système nerveux; Diagnostic; Lévodopa; Homme; Parkine; Psychogène
FG :	Trouble somatoforme
ED :	Parkinsonism; Somatic conversion; Chronic fatigue syndrome; Nervous system diseases; Diagnosis; Levodopa; Human; Parkin; Psychogenic
EG :	Somatoform disorder
SD :	Parkinson síndrome; Conversion somática; Fatiga crónica síndrome; Sistema nervioso patología; Diagnóstico; Levodopa; Hombre; Parkin; Psicógeno
LO :	INIST-20953.354000190480410210
ID :	11-0321221

Links to Exploration step

Pascal:11-0321221

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chronic fatigue syndrome</term>
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<front><div type="abstract" xml:lang="en">Background: We report 4 patients with young-onset monogenetic parkinsonism, each of whom was misdiagnosed with either a psychogenic movement disorder or chronic fatigue syndrome for 10 to 23 years after the onset of their first symptoms. Results: Once the diagnosis was eventually made, they all had a rapid and excellent response to levodopa, albeit with the early appearance of interdose dyskinesias in 3. Conclusions: We discuss possible reasons for the missed diagnosis despite the relentless progression of their motor handicap. DAT scanning supported the revised clinical diagnosis of parkinsonism.</div>
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<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Background: We report 4 patients with young-onset monogenetic parkinsonism, each of whom was misdiagnosed with either a psychogenic movement disorder or chronic fatigue syndrome for 10 to 23 years after the onset of their first symptoms. Results: Once the diagnosis was eventually made, they all had a rapid and excellent response to levodopa, albeit with the early appearance of interdose dyskinesias in 3. Conclusions: We discuss possible reasons for the missed diagnosis despite the relentless progression of their motor handicap. DAT scanning supported the revised clinical diagnosis of parkinsonism.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B17F</s0>
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<fC03 i1="01" i2="X" l="FRE"><s0>Parkinsonisme</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Parkinsonism</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Parkinson síndrome</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Conversion somatique</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Somatic conversion</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Conversion somática</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Syndrome de fatigue chronique</s0>
<s2>NM</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Chronic fatigue syndrome</s0>
<s2>NM</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Fatiga crónica síndrome</s0>
<s2>NM</s2>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Pathologie du   système nerveux</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Diagnostic</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Diagnosis</s0>
<s5>09</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Diagnóstico</s0>
<s5>09</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Lévodopa</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Levodopa</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>10</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Levodopa</s0>
<s2>NK</s2>
<s2>FR</s2>
<s5>10</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Homme</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Human</s0>
<s5>11</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Hombre</s0>
<s5>11</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Parkine</s0>
<s5>12</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Parkin</s0>
<s5>12</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Parkin</s0>
<s5>12</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Psychogène</s0>
<s5>13</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Psychogenic</s0>
<s5>13</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Psicógeno</s0>
<s5>13</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Trouble somatoforme</s0>
<s2>NM</s2>
<s5>38</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Somatoform disorder</s0>
<s2>NM</s2>
<s5>38</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Trastorno somatoformo</s0>
<s2>NM</s2>
<s5>38</s5>
</fC07>
<fN21><s1>220</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
<server><NO>PASCAL 11-0321221 INIST</NO>
<ET>Decades of Delayed Diagnosis in 4 Levodopa-Responsive Young-Onset Monogenetic Parkinsonism Patients</ET>
<AU>LING (Helen); BRASCHINSKY (Mark); TABA (Pille); LUUS (Siiri-Merike); DOHERTY (Karen); HOTTER (Anna); POEWE (Werner); LEES (Andrew J.)</AU>
<AF>Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London/London/Royaume-Uni (1 aut., 5 aut., 8 aut.); Queen Square Brain Bank for Neurological Disorders and Institute of Neurology, University College London/London/Royaume-Uni (1 aut., 5 aut., 8 aut.); Department of Neurology, University of Tartu/Tartu/Estonie (2 aut., 3 aut., 4 aut.); Department of Neurology, University Hospital of Innsbruck/Autriche (6 aut., 7 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2011; Vol. 26; No. 7; Pp. 1337-1340; Bibl. 8 ref.</SO>
<LA>Anglais</LA>
<EA>Background: We report 4 patients with young-onset monogenetic parkinsonism, each of whom was misdiagnosed with either a psychogenic movement disorder or chronic fatigue syndrome for 10 to 23 years after the onset of their first symptoms. Results: Once the diagnosis was eventually made, they all had a rapid and excellent response to levodopa, albeit with the early appearance of interdose dyskinesias in 3. Conclusions: We discuss possible reasons for the missed diagnosis despite the relentless progression of their motor handicap. DAT scanning supported the revised clinical diagnosis of parkinsonism.</EA>
<CC>002B17; 002B17F</CC>
<FD>Parkinsonisme; Conversion somatique; Syndrome de fatigue chronique; Pathologie du   système nerveux; Diagnostic; Lévodopa; Homme; Parkine; Psychogène</FD>
<FG>Trouble somatoforme</FG>
<ED>Parkinsonism; Somatic conversion; Chronic fatigue syndrome; Nervous system diseases; Diagnosis; Levodopa; Human; Parkin; Psychogenic</ED>
<EG>Somatoform disorder</EG>
<SD>Parkinson síndrome; Conversion somática; Fatiga crónica síndrome; Sistema nervioso patología; Diagnóstico; Levodopa; Hombre; Parkin; Psicógeno</SD>
<LO>INIST-20953.354000190480410210</LO>
<ID>11-0321221</ID>
</server>
</inist>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Decades of Delayed Diagnosis in 4 Levodopa-Responsive Young-Onset Monogenetic Parkinsonism Patients

Decades of Delayed Diagnosis in 4 Levodopa-Responsive Young-Onset Monogenetic Parkinsonism Patients

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