Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging?
Identifieur interne : 000394 ( PascalFrancis/Corpus ); précédent : 000393; suivant : 000395Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging?
Auteurs : Syam Krishnan ; Gangadhara Sarma ; Sankara Sarma ; Asha KishoreSource :
- Movement disorders [ 0885-3185 ] ; 2011.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before. Methods: We performed a prospective case-control study to assess the frequency and severity of nonmotor symptoms in patients with Parkinson's disease (n = 174) and age-matched normal controls (n = 128) using the Non-Motor Symptoms Scale. Results: Nonmotor symptoms in Parkinson's disease were ubiquitous, more frequent, and more severe than in normal aging, particularly in women. Cardiovascular, mood/cognition, and perceptual problems/hallucinations domains were rarely involved in age-matched controls. Age had no effect and sex some influence on nonmotor symptoms in Parkinson's disease. In contrast, in controls, nonmotor symptoms increased with age, and sex had no effect. Conclusions: Nonmotor symptoms in Parkinson's disease differ from those in aging in frequency, severity, sex predilection, and domain involvement.
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NO : | PASCAL 11-0444654 INIST |
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ET : | Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging? |
AU : | KRISHNAN (Syam); SARMA (Gangadhara); SARMA (Sankara); KISHORE (Asha) |
AF : | Comprehensive Care Centre for Movement Disorders, Sree Chitra Tirunal Institute for Medical Sciences and Technology/Kerala/Inde (1 aut., 2 aut., 4 aut.); Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology/Kerala/Inde (3 aut.) |
DT : | Publication en série; Courte communication, note brève; Niveau analytique |
SO : | Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2011; Vol. 26; No. 11; Pp. 2110-2113; Bibl. 28 ref. |
LA : | Anglais |
EA : | Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before. Methods: We performed a prospective case-control study to assess the frequency and severity of nonmotor symptoms in patients with Parkinson's disease (n = 174) and age-matched normal controls (n = 128) using the Non-Motor Symptoms Scale. Results: Nonmotor symptoms in Parkinson's disease were ubiquitous, more frequent, and more severe than in normal aging, particularly in women. Cardiovascular, mood/cognition, and perceptual problems/hallucinations domains were rarely involved in age-matched controls. Age had no effect and sex some influence on nonmotor symptoms in Parkinson's disease. In contrast, in controls, nonmotor symptoms increased with age, and sex had no effect. Conclusions: Nonmotor symptoms in Parkinson's disease differ from those in aging in frequency, severity, sex predilection, and domain involvement. |
CC : | 002B17; 002B17G |
FD : | Maladie de Parkinson; Trouble moteur; Pathologie du système nerveux; Sénescence; Qualité de vie |
FG : | Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Trouble neurologique |
ED : | Parkinson disease; Motor system disorder; Nervous system diseases; Senescence; Quality of life |
EG : | Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Neurological disorder |
SD : | Parkinson enfermedad; Trastorno motor; Sistema nervioso patología; Senescencia; Calidad vida |
LO : | INIST-20953.354000509954560230 |
ID : | 11-0444654 |
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Pascal:11-0444654Le document en format XML
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<front><div type="abstract" xml:lang="en">Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before. Methods: We performed a prospective case-control study to assess the frequency and severity of nonmotor symptoms in patients with Parkinson's disease (n = 174) and age-matched normal controls (n = 128) using the Non-Motor Symptoms Scale. Results: Nonmotor symptoms in Parkinson's disease were ubiquitous, more frequent, and more severe than in normal aging, particularly in women. Cardiovascular, mood/cognition, and perceptual problems/hallucinations domains were rarely involved in age-matched controls. Age had no effect and sex some influence on nonmotor symptoms in Parkinson's disease. In contrast, in controls, nonmotor symptoms increased with age, and sex had no effect. Conclusions: Nonmotor symptoms in Parkinson's disease differ from those in aging in frequency, severity, sex predilection, and domain involvement.</div>
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<ET>Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging?</ET>
<AU>KRISHNAN (Syam); SARMA (Gangadhara); SARMA (Sankara); KISHORE (Asha)</AU>
<AF>Comprehensive Care Centre for Movement Disorders, Sree Chitra Tirunal Institute for Medical Sciences and Technology/Kerala/Inde (1 aut., 2 aut., 4 aut.); Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology/Kerala/Inde (3 aut.)</AF>
<DT>Publication en série; Courte communication, note brève; Niveau analytique</DT>
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<LA>Anglais</LA>
<EA>Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before. Methods: We performed a prospective case-control study to assess the frequency and severity of nonmotor symptoms in patients with Parkinson's disease (n = 174) and age-matched normal controls (n = 128) using the Non-Motor Symptoms Scale. Results: Nonmotor symptoms in Parkinson's disease were ubiquitous, more frequent, and more severe than in normal aging, particularly in women. Cardiovascular, mood/cognition, and perceptual problems/hallucinations domains were rarely involved in age-matched controls. Age had no effect and sex some influence on nonmotor symptoms in Parkinson's disease. In contrast, in controls, nonmotor symptoms increased with age, and sex had no effect. Conclusions: Nonmotor symptoms in Parkinson's disease differ from those in aging in frequency, severity, sex predilection, and domain involvement.</EA>
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