Movement Disorders (revue)

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Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging?

Identifieur interne : 000394 ( PascalFrancis/Corpus ); précédent : 000393; suivant : 000395

Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging?

Auteurs : Syam Krishnan ; Gangadhara Sarma ; Sankara Sarma ; Asha Kishore

Source :

RBID : Pascal:11-0444654

Descripteurs français

English descriptors

Abstract

Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before. Methods: We performed a prospective case-control study to assess the frequency and severity of nonmotor symptoms in patients with Parkinson's disease (n = 174) and age-matched normal controls (n = 128) using the Non-Motor Symptoms Scale. Results: Nonmotor symptoms in Parkinson's disease were ubiquitous, more frequent, and more severe than in normal aging, particularly in women. Cardiovascular, mood/cognition, and perceptual problems/hallucinations domains were rarely involved in age-matched controls. Age had no effect and sex some influence on nonmotor symptoms in Parkinson's disease. In contrast, in controls, nonmotor symptoms increased with age, and sex had no effect. Conclusions: Nonmotor symptoms in Parkinson's disease differ from those in aging in frequency, severity, sex predilection, and domain involvement.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A03   1    @0 Mov. disord.
A05       @2 26
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A08 01  1  ENG  @1 Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging?
A11 01  1    @1 KRISHNAN (Syam)
A11 02  1    @1 SARMA (Gangadhara)
A11 03  1    @1 SARMA (Sankara)
A11 04  1    @1 KISHORE (Asha)
A14 01      @1 Comprehensive Care Centre for Movement Disorders, Sree Chitra Tirunal Institute for Medical Sciences and Technology @2 Kerala @3 IND @Z 1 aut. @Z 2 aut. @Z 4 aut.
A14 02      @1 Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology @2 Kerala @3 IND @Z 3 aut.
A20       @1 2110-2113
A21       @1 2011
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A43 01      @1 INIST @2 20953 @5 354000509954560230
A44       @0 0000 @1 © 2011 INIST-CNRS. All rights reserved.
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A47 01  1    @0 11-0444654
A60       @1 P @3 CC
A61       @0 A
A64 01  1    @0 Movement disorders
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C01 01    ENG  @0 Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before. Methods: We performed a prospective case-control study to assess the frequency and severity of nonmotor symptoms in patients with Parkinson's disease (n = 174) and age-matched normal controls (n = 128) using the Non-Motor Symptoms Scale. Results: Nonmotor symptoms in Parkinson's disease were ubiquitous, more frequent, and more severe than in normal aging, particularly in women. Cardiovascular, mood/cognition, and perceptual problems/hallucinations domains were rarely involved in age-matched controls. Age had no effect and sex some influence on nonmotor symptoms in Parkinson's disease. In contrast, in controls, nonmotor symptoms increased with age, and sex had no effect. Conclusions: Nonmotor symptoms in Parkinson's disease differ from those in aging in frequency, severity, sex predilection, and domain involvement.
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C03 05  X  SPA  @0 Calidad vida @5 10
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C07 01  X  ENG  @0 Cerebral disorder @5 37
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C07 02  X  FRE  @0 Syndrome extrapyramidal @5 38
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C07 05  X  FRE  @0 Trouble neurologique @5 42
C07 05  X  ENG  @0 Neurological disorder @5 42
C07 05  X  SPA  @0 Trastorno neurológico @5 42
N21       @1 305
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Format Inist (serveur)

NO : PASCAL 11-0444654 INIST
ET : Do Nonmotor Symptoms in Parkinson's Disease Differ from Normal Aging?
AU : KRISHNAN (Syam); SARMA (Gangadhara); SARMA (Sankara); KISHORE (Asha)
AF : Comprehensive Care Centre for Movement Disorders, Sree Chitra Tirunal Institute for Medical Sciences and Technology/Kerala/Inde (1 aut., 2 aut., 4 aut.); Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology/Kerala/Inde (3 aut.)
DT : Publication en série; Courte communication, note brève; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2011; Vol. 26; No. 11; Pp. 2110-2113; Bibl. 28 ref.
LA : Anglais
EA : Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before. Methods: We performed a prospective case-control study to assess the frequency and severity of nonmotor symptoms in patients with Parkinson's disease (n = 174) and age-matched normal controls (n = 128) using the Non-Motor Symptoms Scale. Results: Nonmotor symptoms in Parkinson's disease were ubiquitous, more frequent, and more severe than in normal aging, particularly in women. Cardiovascular, mood/cognition, and perceptual problems/hallucinations domains were rarely involved in age-matched controls. Age had no effect and sex some influence on nonmotor symptoms in Parkinson's disease. In contrast, in controls, nonmotor symptoms increased with age, and sex had no effect. Conclusions: Nonmotor symptoms in Parkinson's disease differ from those in aging in frequency, severity, sex predilection, and domain involvement.
CC : 002B17; 002B17G
FD : Maladie de Parkinson; Trouble moteur; Pathologie du système nerveux; Sénescence; Qualité de vie
FG : Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Trouble neurologique
ED : Parkinson disease; Motor system disorder; Nervous system diseases; Senescence; Quality of life
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Neurological disorder
SD : Parkinson enfermedad; Trastorno motor; Sistema nervioso patología; Senescencia; Calidad vida
LO : INIST-20953.354000509954560230
ID : 11-0444654

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Pascal:11-0444654

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<SO>Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2011; Vol. 26; No. 11; Pp. 2110-2113; Bibl. 28 ref.</SO>
<LA>Anglais</LA>
<EA>Background: Nonmotor symptoms in Parkinson's disease are frequent and affect health-related quality of life of patients. The severity and domains of nonmotor symptoms involved in Parkinson's disease and normal aging have not been compared before. Methods: We performed a prospective case-control study to assess the frequency and severity of nonmotor symptoms in patients with Parkinson's disease (n = 174) and age-matched normal controls (n = 128) using the Non-Motor Symptoms Scale. Results: Nonmotor symptoms in Parkinson's disease were ubiquitous, more frequent, and more severe than in normal aging, particularly in women. Cardiovascular, mood/cognition, and perceptual problems/hallucinations domains were rarely involved in age-matched controls. Age had no effect and sex some influence on nonmotor symptoms in Parkinson's disease. In contrast, in controls, nonmotor symptoms increased with age, and sex had no effect. Conclusions: Nonmotor symptoms in Parkinson's disease differ from those in aging in frequency, severity, sex predilection, and domain involvement.</EA>
<CC>002B17; 002B17G</CC>
<FD>Maladie de Parkinson; Trouble moteur; Pathologie du système nerveux; Sénescence; Qualité de vie</FD>
<FG>Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central; Trouble neurologique</FG>
<ED>Parkinson disease; Motor system disorder; Nervous system diseases; Senescence; Quality of life</ED>
<EG>Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease; Neurological disorder</EG>
<SD>Parkinson enfermedad; Trastorno motor; Sistema nervioso patología; Senescencia; Calidad vida</SD>
<LO>INIST-20953.354000509954560230</LO>
<ID>11-0444654</ID>
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