Movement Disorders (revue)

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Suggested Immobilization Test for Diagnosis of Restless Legs Syndrome in Parkinson's Disease

Identifieur interne : 000182 ( PascalFrancis/Corpus ); précédent : 000181; suivant : 000183

Suggested Immobilization Test for Diagnosis of Restless Legs Syndrome in Parkinson's Disease

Auteurs : Valérie Cochen De Cock ; Sophie Bayard ; HUAN YU ; Magda Grini ; Bertrand Carlander ; Ron Postuma ; Mahmoud Charif ; Yves Dauvilliers

Source :

RBID : Pascal:12-0248758

Descripteurs français

English descriptors

Abstract

Diagnosis of restless leg syndrome (RLS) in Parkinson's disease (PD) is difficult because of clinical confounds. The suggested immobilization test (SIT) is validated for diagnosis of primary RLS. This study evaluated the usefulness of the SIT for diagnosis of RLS in PD. We compared SIT scores, as well as polysomnography measures in 50 patients with PD (25 with RLS, 25 without), 25 patients with primary RLS, and 25 age/sex matched controls. Mean leg discomfort score was increased in patients with PD and RLS compared to PD without RLS, and also in patients with primary RLS compared to controls. Leg discomfort was significantly higher at the end of the test in patients with RLS compared to patients without RLS. Intensity of leg discomfort was similar between patients with RLS, with or without PD. Using a mean leg discomfort cutoff of 11, we showed sensitivity of 91% and specificity of 72% for RLS diagnosis in PD during symptomatic time intervals. Periodic leg movements index during the SIT did not differ between groups. Periodic leg movements index during sleep and wakefulness was increased in patients with primary RLS compared to controls, but did not differ between patients with PD, with and without RLS. The sensory SIT is a simple test that may help diagnose RLS in patients with PD.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0885-3185
A03   1    @0 Mov. disord.
A05       @2 27
A06       @2 6
A08 01  1  ENG  @1 Suggested Immobilization Test for Diagnosis of Restless Legs Syndrome in Parkinson's Disease
A11 01  1    @1 DE COCK (Valérie Cochen)
A11 02  1    @1 BAYARD (Sophie)
A11 03  1    @1 HUAN YU
A11 04  1    @1 GRINI (Magda)
A11 05  1    @1 CARLANDER (Bertrand)
A11 06  1    @1 POSTUMA (Ron)
A11 07  1    @1 CHARIF (Mahmoud)
A11 08  1    @1 DAUVILLIERS (Yves)
A14 01      @1 Unité des troubles du sommeil, Service de Neurologie, Hôpital Gui de Chauliac @2 Montpellier @3 FRA @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 5 aut. @Z 8 aut.
A14 02      @1 Service de Neurologie, Hôpital Gui de Chauliac @2 Montpellier @3 FRA @Z 1 aut. @Z 4 aut. @Z 5 aut. @Z 7 aut. @Z 8 aut.
A14 03      @1 INSERM U1061 @2 Montpellier @3 FRA @Z 1 aut. @Z 2 aut. @Z 8 aut.
A14 04      @1 Department of Neurology, Shanghai Huashan Hospital, Shangai Fudan University @2 Shangai @3 CHN @Z 3 aut.
A14 05      @1 Department of Neurology, McGill University, Montreal General Hospital @2 Montreal, Ontario @3 CAN @Z 6 aut.
A20       @1 743-749
A21       @1 2012
A23 01      @0 ENG
A43 01      @1 INIST @2 20953 @5 354000507771510140
A44       @0 0000 @1 © 2012 INIST-CNRS. All rights reserved.
A45       @0 39 ref.
A47 01  1    @0 12-0248758
A60       @1 P
A61       @0 A
A64 01  1    @0 Movement disorders
A66 01      @0 USA
C01 01    ENG  @0 Diagnosis of restless leg syndrome (RLS) in Parkinson's disease (PD) is difficult because of clinical confounds. The suggested immobilization test (SIT) is validated for diagnosis of primary RLS. This study evaluated the usefulness of the SIT for diagnosis of RLS in PD. We compared SIT scores, as well as polysomnography measures in 50 patients with PD (25 with RLS, 25 without), 25 patients with primary RLS, and 25 age/sex matched controls. Mean leg discomfort score was increased in patients with PD and RLS compared to PD without RLS, and also in patients with primary RLS compared to controls. Leg discomfort was significantly higher at the end of the test in patients with RLS compared to patients without RLS. Intensity of leg discomfort was similar between patients with RLS, with or without PD. Using a mean leg discomfort cutoff of 11, we showed sensitivity of 91% and specificity of 72% for RLS diagnosis in PD during symptomatic time intervals. Periodic leg movements index during the SIT did not differ between groups. Periodic leg movements index during sleep and wakefulness was increased in patients with primary RLS compared to controls, but did not differ between patients with PD, with and without RLS. The sensory SIT is a simple test that may help diagnose RLS in patients with PD.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C03 01  X  FRE  @0 Syndrome des jambes sans repos @5 01
C03 01  X  ENG  @0 Restless legs syndrome @5 01
C03 01  X  SPA  @0 Acroparestesia nocturna @5 01
C03 02  X  FRE  @0 Maladie de Parkinson @2 NM @5 02
C03 02  X  ENG  @0 Parkinson disease @2 NM @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @2 NM @5 02
C03 03  X  FRE  @0 Pathologie du système nerveux @5 03
C03 03  X  ENG  @0 Nervous system diseases @5 03
C03 03  X  SPA  @0 Sistema nervioso patología @5 03
C03 04  X  FRE  @0 Test immobilisation @5 09
C03 04  X  ENG  @0 Immobilization test @5 09
C03 04  X  SPA  @0 Prueba inmovilización @5 09
C03 05  X  FRE  @0 Diagnostic @5 10
C03 05  X  ENG  @0 Diagnosis @5 10
C03 05  X  SPA  @0 Diagnóstico @5 10
C07 01  X  FRE  @0 Trouble neurologique @5 38
C07 01  X  ENG  @0 Neurological disorder @5 38
C07 01  X  SPA  @0 Trastorno neurológico @5 38
C07 02  X  FRE  @0 Trouble de la sensibilité @5 39
C07 02  X  ENG  @0 Sensitivity disorder @5 39
C07 02  X  SPA  @0 Trastorno sensibilidad @5 39
C07 03  X  FRE  @0 Pathologie de l'encéphale @5 40
C07 03  X  ENG  @0 Cerebral disorder @5 40
C07 03  X  SPA  @0 Encéfalo patología @5 40
C07 04  X  FRE  @0 Syndrome extrapyramidal @5 41
C07 04  X  ENG  @0 Extrapyramidal syndrome @5 41
C07 04  X  SPA  @0 Extrapiramidal síndrome @5 41
C07 05  X  FRE  @0 Maladie dégénérative @5 42
C07 05  X  ENG  @0 Degenerative disease @5 42
C07 05  X  SPA  @0 Enfermedad degenerativa @5 42
C07 06  X  FRE  @0 Pathologie du système nerveux central @5 43
C07 06  X  ENG  @0 Central nervous system disease @5 43
C07 06  X  SPA  @0 Sistema nervosio central patología @5 43
N21       @1 191
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 12-0248758 INIST
ET : Suggested Immobilization Test for Diagnosis of Restless Legs Syndrome in Parkinson's Disease
AU : DE COCK (Valérie Cochen); BAYARD (Sophie); HUAN YU; GRINI (Magda); CARLANDER (Bertrand); POSTUMA (Ron); CHARIF (Mahmoud); DAUVILLIERS (Yves)
AF : Unité des troubles du sommeil, Service de Neurologie, Hôpital Gui de Chauliac/Montpellier/France (1 aut., 2 aut., 3 aut., 5 aut., 8 aut.); Service de Neurologie, Hôpital Gui de Chauliac/Montpellier/France (1 aut., 4 aut., 5 aut., 7 aut., 8 aut.); INSERM U1061/Montpellier/France (1 aut., 2 aut., 8 aut.); Department of Neurology, Shanghai Huashan Hospital, Shangai Fudan University/Shangai/Chine (3 aut.); Department of Neurology, McGill University, Montreal General Hospital/Montreal, Ontario/Canada (6 aut.)
DT : Publication en série; Niveau analytique
SO : Movement disorders; ISSN 0885-3185; Etats-Unis; Da. 2012; Vol. 27; No. 6; Pp. 743-749; Bibl. 39 ref.
LA : Anglais
EA : Diagnosis of restless leg syndrome (RLS) in Parkinson's disease (PD) is difficult because of clinical confounds. The suggested immobilization test (SIT) is validated for diagnosis of primary RLS. This study evaluated the usefulness of the SIT for diagnosis of RLS in PD. We compared SIT scores, as well as polysomnography measures in 50 patients with PD (25 with RLS, 25 without), 25 patients with primary RLS, and 25 age/sex matched controls. Mean leg discomfort score was increased in patients with PD and RLS compared to PD without RLS, and also in patients with primary RLS compared to controls. Leg discomfort was significantly higher at the end of the test in patients with RLS compared to patients without RLS. Intensity of leg discomfort was similar between patients with RLS, with or without PD. Using a mean leg discomfort cutoff of 11, we showed sensitivity of 91% and specificity of 72% for RLS diagnosis in PD during symptomatic time intervals. Periodic leg movements index during the SIT did not differ between groups. Periodic leg movements index during sleep and wakefulness was increased in patients with primary RLS compared to controls, but did not differ between patients with PD, with and without RLS. The sensory SIT is a simple test that may help diagnose RLS in patients with PD.
CC : 002B17; 002B17G
FD : Syndrome des jambes sans repos; Maladie de Parkinson; Pathologie du système nerveux; Test immobilisation; Diagnostic
FG : Trouble neurologique; Trouble de la sensibilité; Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central
ED : Restless legs syndrome; Parkinson disease; Nervous system diseases; Immobilization test; Diagnosis
EG : Neurological disorder; Sensitivity disorder; Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD : Acroparestesia nocturna; Parkinson enfermedad; Sistema nervioso patología; Prueba inmovilización; Diagnóstico
LO : INIST-20953.354000507771510140
ID : 12-0248758

Links to Exploration step

Pascal:12-0248758

Le document en format XML

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<name sortKey="Postuma, Ron" sort="Postuma, Ron" uniqKey="Postuma R" first="Ron" last="Postuma">Ron Postuma</name>
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<div type="abstract" xml:lang="en">Diagnosis of restless leg syndrome (RLS) in Parkinson's disease (PD) is difficult because of clinical confounds. The suggested immobilization test (SIT) is validated for diagnosis of primary RLS. This study evaluated the usefulness of the SIT for diagnosis of RLS in PD. We compared SIT scores, as well as polysomnography measures in 50 patients with PD (25 with RLS, 25 without), 25 patients with primary RLS, and 25 age/sex matched controls. Mean leg discomfort score was increased in patients with PD and RLS compared to PD without RLS, and also in patients with primary RLS compared to controls. Leg discomfort was significantly higher at the end of the test in patients with RLS compared to patients without RLS. Intensity of leg discomfort was similar between patients with RLS, with or without PD. Using a mean leg discomfort cutoff of 11, we showed sensitivity of 91% and specificity of 72% for RLS diagnosis in PD during symptomatic time intervals. Periodic leg movements index during the SIT did not differ between groups. Periodic leg movements index during sleep and wakefulness was increased in patients with primary RLS compared to controls, but did not differ between patients with PD, with and without RLS. The sensory SIT is a simple test that may help diagnose RLS in patients with PD.</div>
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<ET>Suggested Immobilization Test for Diagnosis of Restless Legs Syndrome in Parkinson's Disease</ET>
<AU>DE COCK (Valérie Cochen); BAYARD (Sophie); HUAN YU; GRINI (Magda); CARLANDER (Bertrand); POSTUMA (Ron); CHARIF (Mahmoud); DAUVILLIERS (Yves)</AU>
<AF>Unité des troubles du sommeil, Service de Neurologie, Hôpital Gui de Chauliac/Montpellier/France (1 aut., 2 aut., 3 aut., 5 aut., 8 aut.); Service de Neurologie, Hôpital Gui de Chauliac/Montpellier/France (1 aut., 4 aut., 5 aut., 7 aut., 8 aut.); INSERM U1061/Montpellier/France (1 aut., 2 aut., 8 aut.); Department of Neurology, Shanghai Huashan Hospital, Shangai Fudan University/Shangai/Chine (3 aut.); Department of Neurology, McGill University, Montreal General Hospital/Montreal, Ontario/Canada (6 aut.)</AF>
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<EA>Diagnosis of restless leg syndrome (RLS) in Parkinson's disease (PD) is difficult because of clinical confounds. The suggested immobilization test (SIT) is validated for diagnosis of primary RLS. This study evaluated the usefulness of the SIT for diagnosis of RLS in PD. We compared SIT scores, as well as polysomnography measures in 50 patients with PD (25 with RLS, 25 without), 25 patients with primary RLS, and 25 age/sex matched controls. Mean leg discomfort score was increased in patients with PD and RLS compared to PD without RLS, and also in patients with primary RLS compared to controls. Leg discomfort was significantly higher at the end of the test in patients with RLS compared to patients without RLS. Intensity of leg discomfort was similar between patients with RLS, with or without PD. Using a mean leg discomfort cutoff of 11, we showed sensitivity of 91% and specificity of 72% for RLS diagnosis in PD during symptomatic time intervals. Periodic leg movements index during the SIT did not differ between groups. Periodic leg movements index during sleep and wakefulness was increased in patients with primary RLS compared to controls, but did not differ between patients with PD, with and without RLS. The sensory SIT is a simple test that may help diagnose RLS in patients with PD.</EA>
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