Movement Disorders (revue)

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Cortical motor activation in akinetic schizophrenic patients: A pilot functional MRI study

Identifieur interne : 002193 ( PascalFrancis/Checkpoint ); précédent : 002192; suivant : 002194

Cortical motor activation in akinetic schizophrenic patients: A pilot functional MRI study

Auteurs : Pierre Payoux [France] ; Kader Boulanouar [France] ; Christine Sarramon [France] ; Nelly Fabre [France] ; Sylvie Descombes [France] ; Monique Galitsky [France] ; Claire Thalamas [France] ; Christine Brefel-Courbon [France] ; Umberto Sabatini [Italie] ; Claude Manelfe [France] ; Francois Chollet [France] ; Laurent Schmitt [France] ; Olivier Rascol [France]

Source :

RBID : Pascal:04-0234531

Descripteurs français

English descriptors

Abstract

Akinesia is associated with supplementary motor area (SMA) dysfunction in Parkinson's disease. We looked for a similar association in patients with schizophrenia. Using functional magnetic resonance imaging (fMRI), we compared motor activation in 6 akinetic neuroleptic-treated schizophrenic patients and 6 normal subjects. Schizophrenic patients had a defective activation in the SMA, left primary sensorimotor cortex, bilateral lateral premotor and inferior parietal cortices, whereas the right primary sensorimotor cortex and a mesial frontal area were hyperactive. SMA was hypoactive in akinetic schizophrenic patients, emphasizing the role of this area in motor slowness. Other abnormal signals likely reflect schizophrenia-related abnormal intracortical connections.


Affiliations:


Links toward previous steps (curation, corpus...)


Links to Exploration step

Pascal:04-0234531

Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en" level="a">Cortical motor activation in akinetic schizophrenic patients: A pilot functional MRI study</title>
<author>
<name sortKey="Payoux, Pierre" sort="Payoux, Pierre" uniqKey="Payoux P" first="Pierre" last="Payoux">Pierre Payoux</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>PET Center, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Boulanouar, Kader" sort="Boulanouar, Kader" uniqKey="Boulanouar K" first="Kader" last="Boulanouar">Kader Boulanouar</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Sarramon, Christine" sort="Sarramon, Christine" uniqKey="Sarramon C" first="Christine" last="Sarramon">Christine Sarramon</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="03">
<s1>Department of Psychiatry, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Fabre, Nelly" sort="Fabre, Nelly" uniqKey="Fabre N" first="Nelly" last="Fabre">Nelly Fabre</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="04">
<s1>Department of Neurology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Descombes, Sylvie" sort="Descombes, Sylvie" uniqKey="Descombes S" first="Sylvie" last="Descombes">Sylvie Descombes</name>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Galitsky, Monique" sort="Galitsky, Monique" uniqKey="Galitsky M" first="Monique" last="Galitsky">Monique Galitsky</name>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Thalamas, Claire" sort="Thalamas, Claire" uniqKey="Thalamas C" first="Claire" last="Thalamas">Claire Thalamas</name>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Brefel Courbon, Christine" sort="Brefel Courbon, Christine" uniqKey="Brefel Courbon C" first="Christine" last="Brefel-Courbon">Christine Brefel-Courbon</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="06">
<s1>Department of Clinical Pharmacology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Sabatini, Umberto" sort="Sabatini, Umberto" uniqKey="Sabatini U" first="Umberto" last="Sabatini">Umberto Sabatini</name>
<affiliation wicri:level="3">
<inist:fA14 i1="07">
<s1>Istituto di Ricovero e Cura a Carattere Scientifico, Fondazione Santa Lucia</s1>
<s2>Rome</s2>
<s3>ITA</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<placeName>
<settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Manelfe, Claude" sort="Manelfe, Claude" uniqKey="Manelfe C" first="Claude" last="Manelfe">Claude Manelfe</name>
<affiliation wicri:level="1">
<inist:fA14 i1="08">
<s1>Department of Neuroradiology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Chollet, Francois" sort="Chollet, Francois" uniqKey="Chollet F" first="Francois" last="Chollet">Francois Chollet</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>PET Center, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="04">
<s1>Department of Neurology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Schmitt, Laurent" sort="Schmitt, Laurent" uniqKey="Schmitt L" first="Laurent" last="Schmitt">Laurent Schmitt</name>
<affiliation wicri:level="1">
<inist:fA14 i1="03">
<s1>Department of Psychiatry, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
<placeName>
<settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Midi-Pyrénées</region>
</placeName>
<orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>PET Center, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
<placeName>
<settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Midi-Pyrénées</region>
</placeName>
<orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
<placeName>
<settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Midi-Pyrénées</region>
</placeName>
<orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="06">
<s1>Department of Clinical Pharmacology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
<placeName>
<settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Midi-Pyrénées</region>
</placeName>
<orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">INIST</idno>
<idno type="inist">04-0234531</idno>
<date when="2004">2004</date>
<idno type="stanalyst">PASCAL 04-0234531 INIST</idno>
<idno type="RBID">Pascal:04-0234531</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">002216</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000B05</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">002193</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en" level="a">Cortical motor activation in akinetic schizophrenic patients: A pilot functional MRI study</title>
<author>
<name sortKey="Payoux, Pierre" sort="Payoux, Pierre" uniqKey="Payoux P" first="Pierre" last="Payoux">Pierre Payoux</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>PET Center, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Boulanouar, Kader" sort="Boulanouar, Kader" uniqKey="Boulanouar K" first="Kader" last="Boulanouar">Kader Boulanouar</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Sarramon, Christine" sort="Sarramon, Christine" uniqKey="Sarramon C" first="Christine" last="Sarramon">Christine Sarramon</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="03">
<s1>Department of Psychiatry, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Fabre, Nelly" sort="Fabre, Nelly" uniqKey="Fabre N" first="Nelly" last="Fabre">Nelly Fabre</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="04">
<s1>Department of Neurology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Descombes, Sylvie" sort="Descombes, Sylvie" uniqKey="Descombes S" first="Sylvie" last="Descombes">Sylvie Descombes</name>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Galitsky, Monique" sort="Galitsky, Monique" uniqKey="Galitsky M" first="Monique" last="Galitsky">Monique Galitsky</name>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Thalamas, Claire" sort="Thalamas, Claire" uniqKey="Thalamas C" first="Claire" last="Thalamas">Claire Thalamas</name>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Brefel Courbon, Christine" sort="Brefel Courbon, Christine" uniqKey="Brefel Courbon C" first="Christine" last="Brefel-Courbon">Christine Brefel-Courbon</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="06">
<s1>Department of Clinical Pharmacology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Sabatini, Umberto" sort="Sabatini, Umberto" uniqKey="Sabatini U" first="Umberto" last="Sabatini">Umberto Sabatini</name>
<affiliation wicri:level="3">
<inist:fA14 i1="07">
<s1>Istituto di Ricovero e Cura a Carattere Scientifico, Fondazione Santa Lucia</s1>
<s2>Rome</s2>
<s3>ITA</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>Italie</country>
<placeName>
<settlement type="city">Rome</settlement>
<region nuts="2">Latium</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Manelfe, Claude" sort="Manelfe, Claude" uniqKey="Manelfe C" first="Claude" last="Manelfe">Claude Manelfe</name>
<affiliation wicri:level="1">
<inist:fA14 i1="08">
<s1>Department of Neuroradiology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Chollet, Francois" sort="Chollet, Francois" uniqKey="Chollet F" first="Francois" last="Chollet">Francois Chollet</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>PET Center, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="04">
<s1>Department of Neurology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Schmitt, Laurent" sort="Schmitt, Laurent" uniqKey="Schmitt L" first="Laurent" last="Schmitt">Laurent Schmitt</name>
<affiliation wicri:level="1">
<inist:fA14 i1="03">
<s1>Department of Psychiatry, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<affiliation wicri:level="1">
<inist:fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
<placeName>
<settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Midi-Pyrénées</region>
</placeName>
<orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="02">
<s1>PET Center, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
<placeName>
<settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Midi-Pyrénées</region>
</placeName>
<orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
<placeName>
<settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Midi-Pyrénées</region>
</placeName>
<orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName>
</affiliation>
<affiliation wicri:level="1">
<inist:fA14 i1="06">
<s1>Department of Clinical Pharmacology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName>
<settlement type="city">Toulouse</settlement>
</placeName>
<placeName>
<settlement type="city">Toulouse</settlement>
<region type="region" nuts="2">Midi-Pyrénées</region>
</placeName>
<orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName>
<orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName>
</affiliation>
</author>
</analytic>
<series>
<title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint>
<date when="2004">2004</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt>
<title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Human</term>
<term>Nervous system diseases</term>
<term>Nuclear magnetic resonance imaging</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Système nerveux pathologie</term>
<term>Homme</term>
<term>Imagerie RMN</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Akinesia is associated with supplementary motor area (SMA) dysfunction in Parkinson's disease. We looked for a similar association in patients with schizophrenia. Using functional magnetic resonance imaging (fMRI), we compared motor activation in 6 akinetic neuroleptic-treated schizophrenic patients and 6 normal subjects. Schizophrenic patients had a defective activation in the SMA, left primary sensorimotor cortex, bilateral lateral premotor and inferior parietal cortices, whereas the right primary sensorimotor cortex and a mesial frontal area were hyperactive. SMA was hypoactive in akinetic schizophrenic patients, emphasizing the role of this area in motor slowness. Other abnormal signals likely reflect schizophrenia-related abnormal intracortical connections.</div>
</front>
</TEI>
<inist>
<standard h6="B">
<pA>
<fA01 i1="01" i2="1">
<s0>0885-3185</s0>
</fA01>
<fA03 i2="1">
<s0>Mov. disord.</s0>
</fA03>
<fA05>
<s2>19</s2>
</fA05>
<fA06>
<s2>1</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG">
<s1>Cortical motor activation in akinetic schizophrenic patients: A pilot functional MRI study</s1>
</fA08>
<fA11 i1="01" i2="1">
<s1>PAYOUX (Pierre)</s1>
</fA11>
<fA11 i1="02" i2="1">
<s1>BOULANOUAR (Kader)</s1>
</fA11>
<fA11 i1="03" i2="1">
<s1>SARRAMON (Christine)</s1>
</fA11>
<fA11 i1="04" i2="1">
<s1>FABRE (Nelly)</s1>
</fA11>
<fA11 i1="05" i2="1">
<s1>DESCOMBES (Sylvie)</s1>
</fA11>
<fA11 i1="06" i2="1">
<s1>GALITSKY (Monique)</s1>
</fA11>
<fA11 i1="07" i2="1">
<s1>THALAMAS (Claire)</s1>
</fA11>
<fA11 i1="08" i2="1">
<s1>BREFEL-COURBON (Christine)</s1>
</fA11>
<fA11 i1="09" i2="1">
<s1>SABATINI (Umberto)</s1>
</fA11>
<fA11 i1="10" i2="1">
<s1>MANELFE (Claude)</s1>
</fA11>
<fA11 i1="11" i2="1">
<s1>CHOLLET (Francois)</s1>
</fA11>
<fA11 i1="12" i2="1">
<s1>SCHMITT (Laurent)</s1>
</fA11>
<fA11 i1="13" i2="1">
<s1>RASCOL (Olivier)</s1>
</fA11>
<fA14 i1="01">
<s1>INSERM U 455</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="02">
<s1>PET Center, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>11 aut.</sZ>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="03">
<s1>Department of Psychiatry, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
<sZ>12 aut.</sZ>
</fA14>
<fA14 i1="04">
<s1>Department of Neurology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>11 aut.</sZ>
</fA14>
<fA14 i1="05">
<s1>Clinical Investigation Centre, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="06">
<s1>Department of Clinical Pharmacology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="07">
<s1>Istituto di Ricovero e Cura a Carattere Scientifico, Fondazione Santa Lucia</s1>
<s2>Rome</s2>
<s3>ITA</s3>
<sZ>9 aut.</sZ>
</fA14>
<fA14 i1="08">
<s1>Department of Neuroradiology, University Hospital of Toulouse</s1>
<s2>Toulouse</s2>
<s3>FRA</s3>
<sZ>10 aut.</sZ>
</fA14>
<fA20>
<s1>83-90</s1>
</fA20>
<fA21>
<s1>2004</s1>
</fA21>
<fA23 i1="01">
<s0>ENG</s0>
</fA23>
<fA43 i1="01">
<s1>INIST</s1>
<s2>20953</s2>
<s5>354000111549200140</s5>
</fA43>
<fA44>
<s0>0000</s0>
<s1>© 2004 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45>
<s0>32 ref.</s0>
</fA45>
<fA47 i1="01" i2="1">
<s0>04-0234531</s0>
</fA47>
<fA60>
<s1>P</s1>
<s3>CC</s3>
</fA60>
<fA61>
<s0>A</s0>
</fA61>
<fA64 i1="01" i2="1">
<s0>Movement disorders</s0>
</fA64>
<fA66 i1="01">
<s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG">
<s0>Akinesia is associated with supplementary motor area (SMA) dysfunction in Parkinson's disease. We looked for a similar association in patients with schizophrenia. Using functional magnetic resonance imaging (fMRI), we compared motor activation in 6 akinetic neuroleptic-treated schizophrenic patients and 6 normal subjects. Schizophrenic patients had a defective activation in the SMA, left primary sensorimotor cortex, bilateral lateral premotor and inferior parietal cortices, whereas the right primary sensorimotor cortex and a mesial frontal area were hyperactive. SMA was hypoactive in akinetic schizophrenic patients, emphasizing the role of this area in motor slowness. Other abnormal signals likely reflect schizophrenia-related abnormal intracortical connections.</s0>
</fC01>
<fC02 i1="01" i2="X">
<s0>002B17</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE">
<s0>Système nerveux pathologie</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG">
<s0>Nervous system diseases</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA">
<s0>Sistema nervioso patología</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE">
<s0>Homme</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG">
<s0>Human</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA">
<s0>Hombre</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE">
<s0>Imagerie RMN</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG">
<s0>Nuclear magnetic resonance imaging</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA">
<s0>Imaginería RMN</s0>
<s5>03</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE">
<s0>Imagerie médicale</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG">
<s0>Medical imagery</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA">
<s0>Imaginería médica</s0>
<s5>37</s5>
</fC07>
<fN21>
<s1>152</s1>
</fN21>
<fN82>
<s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations>
<list>
<country>
<li>France</li>
<li>Italie</li>
</country>
<region>
<li>Latium</li>
<li>Midi-Pyrénées</li>
</region>
<settlement>
<li>Rome</li>
<li>Toulouse</li>
</settlement>
<orgName>
<li>Université Toulouse III - Paul Sabatier</li>
<li>Université de Toulouse</li>
</orgName>
</list>
<tree>
<country name="France">
<noRegion>
<name sortKey="Payoux, Pierre" sort="Payoux, Pierre" uniqKey="Payoux P" first="Pierre" last="Payoux">Pierre Payoux</name>
</noRegion>
<name sortKey="Boulanouar, Kader" sort="Boulanouar, Kader" uniqKey="Boulanouar K" first="Kader" last="Boulanouar">Kader Boulanouar</name>
<name sortKey="Brefel Courbon, Christine" sort="Brefel Courbon, Christine" uniqKey="Brefel Courbon C" first="Christine" last="Brefel-Courbon">Christine Brefel-Courbon</name>
<name sortKey="Brefel Courbon, Christine" sort="Brefel Courbon, Christine" uniqKey="Brefel Courbon C" first="Christine" last="Brefel-Courbon">Christine Brefel-Courbon</name>
<name sortKey="Chollet, Francois" sort="Chollet, Francois" uniqKey="Chollet F" first="Francois" last="Chollet">Francois Chollet</name>
<name sortKey="Chollet, Francois" sort="Chollet, Francois" uniqKey="Chollet F" first="Francois" last="Chollet">Francois Chollet</name>
<name sortKey="Chollet, Francois" sort="Chollet, Francois" uniqKey="Chollet F" first="Francois" last="Chollet">Francois Chollet</name>
<name sortKey="Descombes, Sylvie" sort="Descombes, Sylvie" uniqKey="Descombes S" first="Sylvie" last="Descombes">Sylvie Descombes</name>
<name sortKey="Fabre, Nelly" sort="Fabre, Nelly" uniqKey="Fabre N" first="Nelly" last="Fabre">Nelly Fabre</name>
<name sortKey="Fabre, Nelly" sort="Fabre, Nelly" uniqKey="Fabre N" first="Nelly" last="Fabre">Nelly Fabre</name>
<name sortKey="Galitsky, Monique" sort="Galitsky, Monique" uniqKey="Galitsky M" first="Monique" last="Galitsky">Monique Galitsky</name>
<name sortKey="Manelfe, Claude" sort="Manelfe, Claude" uniqKey="Manelfe C" first="Claude" last="Manelfe">Claude Manelfe</name>
<name sortKey="Payoux, Pierre" sort="Payoux, Pierre" uniqKey="Payoux P" first="Pierre" last="Payoux">Pierre Payoux</name>
<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
<name sortKey="Sarramon, Christine" sort="Sarramon, Christine" uniqKey="Sarramon C" first="Christine" last="Sarramon">Christine Sarramon</name>
<name sortKey="Sarramon, Christine" sort="Sarramon, Christine" uniqKey="Sarramon C" first="Christine" last="Sarramon">Christine Sarramon</name>
<name sortKey="Schmitt, Laurent" sort="Schmitt, Laurent" uniqKey="Schmitt L" first="Laurent" last="Schmitt">Laurent Schmitt</name>
<name sortKey="Thalamas, Claire" sort="Thalamas, Claire" uniqKey="Thalamas C" first="Claire" last="Thalamas">Claire Thalamas</name>
</country>
<country name="Italie">
<region name="Latium">
<name sortKey="Sabatini, Umberto" sort="Sabatini, Umberto" uniqKey="Sabatini U" first="Umberto" last="Sabatini">Umberto Sabatini</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PascalFrancis/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002193 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Checkpoint/biblio.hfd -nk 002193 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    PascalFrancis
   |étape=   Checkpoint
   |type=    RBID
   |clé=     Pascal:04-0234531
   |texte=   Cortical motor activation in akinetic schizophrenic patients: A pilot functional MRI study
}}

Wicri

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024