Neuropsychiatric and cognitive features in autosomal-recessive early parkinsonism due to PINK1 mutations
Identifieur interne : 001567 ( PascalFrancis/Checkpoint ); précédent : 001566; suivant : 001568Neuropsychiatric and cognitive features in autosomal-recessive early parkinsonism due to PINK1 mutations
Auteurs : Lilach Ephraty [Israël] ; Omer Porat [Israël] ; David Israeli [Israël] ; Oren S. Cohen [Israël] ; Olga Tunkel [Israël] ; Shinar Yael [Israël] ; Yasaku Hatano [Japon] ; Nobutaka Hattori [Japon] ; Sharon Hassin-Baer [Israël]Source :
- Movement disorders [ 0885-3185 ] ; 2007.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Autosomal-recessive early-onset Parkinsonism (AREP) due to PINK1 mutations is characterized by an early-onset, slowly progressive disease, with a good response to levodopa. Psychiatric and cognitive disturbances associated with AREP have rarely been reported in the literature. We describe 2 brothers from a Jewish-Iraqi consanguineous family with a homozygous PINK1 nonsense mutation. Both patients presented with anxiety and dysphoria accompanied by a gait disturbance that developed subsequently into a clinical depression. During the course of the disease, both developed drug-induced behavioral disturbances of the hedonistic homeostatic dysregulation type and 1 had drug-induced psychosis. The first patient had been diagnosed with mild mental retardation and during the 22 years of disease had further deteriorated; the second developed frontal-type dementia at an early age, 20 years after onset. Their father had a psychiatric disorder but no Parkinsonism. This report expands the phenotypic profile of PINK1-related disease, presenting unique psychiatric and cognitive features as part of the clinical picture.
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
Pascal:07-0210961Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Neuropsychiatric and cognitive features in autosomal-recessive early parkinsonism due to PINK1 mutations</title><author><name sortKey="Ephraty, Lilach" sort="Ephraty, Lilach" uniqKey="Ephraty L" first="Lilach" last="Ephraty">Lilach Ephraty</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Porat, Omer" sort="Porat, Omer" uniqKey="Porat O" first="Omer" last="Porat">Omer Porat</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Israeli, David" sort="Israeli, David" uniqKey="Israeli D" first="David" last="Israeli">David Israeli</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Psychiatry, Chaim Sheba Medical Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>3 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Cohen, Oren S" sort="Cohen, Oren S" uniqKey="Cohen O" first="Oren S." last="Cohen">Oren S. Cohen</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Tunkel, Olga" sort="Tunkel, Olga" uniqKey="Tunkel O" first="Olga" last="Tunkel">Olga Tunkel</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Yael, Shinar" sort="Yael, Shinar" uniqKey="Yael S" first="Shinar" last="Yael">Shinar Yael</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Hatano, Yasaku" sort="Hatano, Yasaku" uniqKey="Hatano Y" first="Yasaku" last="Hatano">Yasaku Hatano</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurology, Juntendo University School of Medicine</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>7 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Hattori, Nobutaka" sort="Hattori, Nobutaka" uniqKey="Hattori N" first="Nobutaka" last="Hattori">Nobutaka Hattori</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurology, Juntendo University School of Medicine</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>7 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Hassin Baer, Sharon" sort="Hassin Baer, Sharon" uniqKey="Hassin Baer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">07-0210961</idno><date when="2007">2007</date><idno type="stanalyst">PASCAL 07-0210961 INIST</idno><idno type="RBID">Pascal:07-0210961</idno><idno type="wicri:Area/PascalFrancis/Corpus">001741</idno><idno type="wicri:Area/PascalFrancis/Curation">001580</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001567</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Neuropsychiatric and cognitive features in autosomal-recessive early parkinsonism due to PINK1 mutations</title><author><name sortKey="Ephraty, Lilach" sort="Ephraty, Lilach" uniqKey="Ephraty L" first="Lilach" last="Ephraty">Lilach Ephraty</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Porat, Omer" sort="Porat, Omer" uniqKey="Porat O" first="Omer" last="Porat">Omer Porat</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Israeli, David" sort="Israeli, David" uniqKey="Israeli D" first="David" last="Israeli">David Israeli</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Psychiatry, Chaim Sheba Medical Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>3 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Cohen, Oren S" sort="Cohen, Oren S" uniqKey="Cohen O" first="Oren S." last="Cohen">Oren S. Cohen</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Tunkel, Olga" sort="Tunkel, Olga" uniqKey="Tunkel O" first="Olga" last="Tunkel">Olga Tunkel</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Yael, Shinar" sort="Yael, Shinar" uniqKey="Yael S" first="Shinar" last="Yael">Shinar Yael</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Hatano, Yasaku" sort="Hatano, Yasaku" uniqKey="Hatano Y" first="Yasaku" last="Hatano">Yasaku Hatano</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurology, Juntendo University School of Medicine</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>7 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Hattori, Nobutaka" sort="Hattori, Nobutaka" uniqKey="Hattori N" first="Nobutaka" last="Hattori">Nobutaka Hattori</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Neurology, Juntendo University School of Medicine</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>7 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Hassin Baer, Sharon" sort="Hassin Baer, Sharon" uniqKey="Hassin Baer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Mutation</term><term>Nervous system diseases</term><term>Neuropsychiatry</term><term>Parkinsonism</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term><term>Parkinsonisme</term><term>Mutation</term><term>Neuropsychiatrie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Autosomal-recessive early-onset Parkinsonism (AREP) due to PINK1 mutations is characterized by an early-onset, slowly progressive disease, with a good response to levodopa. Psychiatric and cognitive disturbances associated with AREP have rarely been reported in the literature. We describe 2 brothers from a Jewish-Iraqi consanguineous family with a homozygous PINK1 nonsense mutation. Both patients presented with anxiety and dysphoria accompanied by a gait disturbance that developed subsequently into a clinical depression. During the course of the disease, both developed drug-induced behavioral disturbances of the hedonistic homeostatic dysregulation type and 1 had drug-induced psychosis. The first patient had been diagnosed with mild mental retardation and during the 22 years of disease had further deteriorated; the second developed frontal-type dementia at an early age, 20 years after onset. Their father had a psychiatric disorder but no Parkinsonism. This report expands the phenotypic profile of PINK1-related disease, presenting unique psychiatric and cognitive features as part of the clinical picture.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0></fA01><fA03 i2="1"><s0>Mov. disord.</s0></fA03><fA05><s2>22</s2></fA05><fA06><s2>4</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Neuropsychiatric and cognitive features in autosomal-recessive early parkinsonism due to PINK1 mutations</s1></fA08><fA11 i1="01" i2="1"><s1>EPHRATY (Lilach)</s1></fA11><fA11 i1="02" i2="1"><s1>PORAT (Omer)</s1></fA11><fA11 i1="03" i2="1"><s1>ISRAELI (David)</s1></fA11><fA11 i1="04" i2="1"><s1>COHEN (Oren S.)</s1></fA11><fA11 i1="05" i2="1"><s1>TUNKEL (Olga)</s1></fA11><fA11 i1="06" i2="1"><s1>YAEL (Shinar)</s1></fA11><fA11 i1="07" i2="1"><s1>HATANO (Yasaku)</s1></fA11><fA11 i1="08" i2="1"><s1>HATTORI (Nobutaka)</s1></fA11><fA11 i1="09" i2="1"><s1>HASSIN-BAER (Sharon)</s1></fA11><fA14 i1="01"><s1>Department of Neurology, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ><sZ>9 aut.</sZ></fA14><fA14 i1="02"><s1>Parkinson's Disease and Movement Disorders Clinic, The Sagol Neuroscience Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>9 aut.</sZ></fA14><fA14 i1="03"><s1>Department of Psychiatry, Chaim Sheba Medical Center, Tel-Aviv University</s1><s2>Tel-Aviv</s2><s3>ISR</s3><sZ>3 aut.</sZ></fA14><fA14 i1="04"><s1>Department of Neurology, Juntendo University School of Medicine</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>7 aut.</sZ><sZ>8 aut.</sZ></fA14><fA20><s1>566-569</s1></fA20><fA21><s1>2007</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20953</s2><s5>354000145702210200</s5></fA43><fA44><s0>0000</s0><s1>© 2007 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>14 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>07-0210961</s0></fA47><fA60><s1>P</s1><s3>CC</s3></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Movement disorders</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>Autosomal-recessive early-onset Parkinsonism (AREP) due to PINK1 mutations is characterized by an early-onset, slowly progressive disease, with a good response to levodopa. Psychiatric and cognitive disturbances associated with AREP have rarely been reported in the literature. We describe 2 brothers from a Jewish-Iraqi consanguineous family with a homozygous PINK1 nonsense mutation. Both patients presented with anxiety and dysphoria accompanied by a gait disturbance that developed subsequently into a clinical depression. During the course of the disease, both developed drug-induced behavioral disturbances of the hedonistic homeostatic dysregulation type and 1 had drug-induced psychosis. The first patient had been diagnosed with mild mental retardation and during the 22 years of disease had further deteriorated; the second developed frontal-type dementia at an early age, 20 years after onset. Their father had a psychiatric disorder but no Parkinsonism. This report expands the phenotypic profile of PINK1-related disease, presenting unique psychiatric and cognitive features as part of the clinical picture.</s0></fC01><fC02 i1="01" i2="X"><s0>002B17</s0></fC02><fC02 i1="02" i2="X"><s0>002B17G</s0></fC02><fC02 i1="03" i2="X"><s0>002B17H</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Parkinsonisme</s0><s2>NM</s2><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Parkinsonism</s0><s2>NM</s2><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Parkinson síndrome</s0><s2>NM</s2><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Mutation</s0><s5>09</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Mutation</s0><s5>09</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Mutación</s0><s5>09</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Neuropsychiatrie</s0><s5>10</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Neuropsychiatry</s0><s5>10</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Neurosiquiatría</s0><s5>10</s5></fC03><fN21><s1>141</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist><affiliations><list><country><li>Israël</li><li>Japon</li></country><settlement><li>Tokyo</li></settlement></list><tree><country name="Israël"><noRegion><name sortKey="Ephraty, Lilach" sort="Ephraty, Lilach" uniqKey="Ephraty L" first="Lilach" last="Ephraty">Lilach Ephraty</name></noRegion><name sortKey="Cohen, Oren S" sort="Cohen, Oren S" uniqKey="Cohen O" first="Oren S." last="Cohen">Oren S. Cohen</name><name sortKey="Cohen, Oren S" sort="Cohen, Oren S" uniqKey="Cohen O" first="Oren S." last="Cohen">Oren S. Cohen</name><name sortKey="Hassin Baer, Sharon" sort="Hassin Baer, Sharon" uniqKey="Hassin Baer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name><name sortKey="Hassin Baer, Sharon" sort="Hassin Baer, Sharon" uniqKey="Hassin Baer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name><name sortKey="Israeli, David" sort="Israeli, David" uniqKey="Israeli D" first="David" last="Israeli">David Israeli</name><name sortKey="Porat, Omer" sort="Porat, Omer" uniqKey="Porat O" first="Omer" last="Porat">Omer Porat</name><name sortKey="Tunkel, Olga" sort="Tunkel, Olga" uniqKey="Tunkel O" first="Olga" last="Tunkel">Olga Tunkel</name><name sortKey="Tunkel, Olga" sort="Tunkel, Olga" uniqKey="Tunkel O" first="Olga" last="Tunkel">Olga Tunkel</name><name sortKey="Yael, Shinar" sort="Yael, Shinar" uniqKey="Yael S" first="Shinar" last="Yael">Shinar Yael</name></country><country name="Japon"><noRegion><name sortKey="Hatano, Yasaku" sort="Hatano, Yasaku" uniqKey="Hatano Y" first="Yasaku" last="Hatano">Yasaku Hatano</name></noRegion><name sortKey="Hattori, Nobutaka" sort="Hattori, Nobutaka" uniqKey="Hattori N" first="Nobutaka" last="Hattori">Nobutaka Hattori</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PascalFrancis/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001567 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Checkpoint/biblio.hfd -nk 001567 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= PascalFrancis
|étape= Checkpoint
|type= RBID
|clé= Pascal:07-0210961
|texte= Neuropsychiatric and cognitive features in autosomal-recessive early parkinsonism due to PINK1 mutations
}}
| This area was generated with Dilib version V0.6.23. |  |