MovDisordV3, PascalFrancis, Checkpoint, bibRecord, 000D96

Myoclonus of Peripheral Origin : Two Case Reports

Identifieur interne : 000D96 ( PascalFrancis/Checkpoint ); précédent : 000D95; suivant : 000D97

Myoclonus of Peripheral Origin : Two Case Reports

Auteurs : Louise Tyvaert [France] ; Pierre Krystkowiak [France] ; Francois Cassim [France] ; Elise Houdayer [France] ; Alexandre Kreisler [France] ; Alain Destée [France] ; Luc Defebvre [France]

Source :

Movement disorders [ 0885-3185 ] ; 2009.

RBID : Pascal:09-0104581

Descripteurs français

Pascal (Inist)
- Myoclonie, Membre fantôme, Pathologie du système nerveux, Etude cas, Douleur.

English descriptors

KwdEn :
- Case study, Myoclonus, Nervous system diseases, Pain, Phantom limb.

Abstract

The concept of peripheral myoclonus is not yet fully accepted by the medical community because ot the difficulty in establishing a cause-and-effect relationship between trauma and subsequent movement disorders. Here, we report two cases of patients suffering from peripheral myoclonus after nerve injury. The first patient experienced myoclonus of the 4th dorsal interosseous muscle several days after trauma to the elbow. The second patient presented myoclonus of the arm stump (combined with phantom-limb pain) 1 year after amputation. In both cases, central nervous system function (spine and brain imaging, somesthetic evoked potentials, EEG back-averaging) was normal. For the second patient, local infiltration of xylocaine and botulinum toxin into the stump scar rapidly stopped myoclonus and pain. Nerve injury induces ephaptic transmission and ectopic excitation. The physiopathological mechanisms of this type of myoclonus involve a peripheral generator that induces central (spinal) generator activity.

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">The concept of peripheral myoclonus is not yet fully accepted by the medical community because ot the difficulty in establishing a cause-and-effect relationship between trauma and subsequent movement disorders. Here, we report two cases of patients suffering from peripheral myoclonus after nerve injury. The first patient experienced myoclonus of the 4th dorsal interosseous muscle several days after trauma to the elbow. The second patient presented myoclonus of the arm stump (combined with phantom-limb pain) 1 year after amputation. In both cases, central nervous system function (spine and brain imaging, somesthetic evoked potentials, EEG back-averaging) was normal. For the second patient, local infiltration of xylocaine and botulinum toxin into the stump scar rapidly stopped myoclonus and pain. Nerve injury induces ephaptic transmission and ectopic excitation. The physiopathological mechanisms of this type of myoclonus involve a peripheral generator that induces central (spinal) generator activity.</div>
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<tree><country name="France"><noRegion><name sortKey="Tyvaert, Louise" sort="Tyvaert, Louise" uniqKey="Tyvaert L" first="Louise" last="Tyvaert">Louise Tyvaert</name>
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<name sortKey="Cassim, Francois" sort="Cassim, Francois" uniqKey="Cassim F" first="Francois" last="Cassim">Francois Cassim</name>
<name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name>
<name sortKey="Destee, Alain" sort="Destee, Alain" uniqKey="Destee A" first="Alain" last="Destee">Alain Destée</name>
<name sortKey="Houdayer, Elise" sort="Houdayer, Elise" uniqKey="Houdayer E" first="Elise" last="Houdayer">Elise Houdayer</name>
<name sortKey="Kreisler, Alexandre" sort="Kreisler, Alexandre" uniqKey="Kreisler A" first="Alexandre" last="Kreisler">Alexandre Kreisler</name>
<name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name>
<name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name>
<name sortKey="Tyvaert, Louise" sort="Tyvaert, Louise" uniqKey="Tyvaert L" first="Louise" last="Tyvaert">Louise Tyvaert</name>
</country>
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</affiliations>
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   |texte=   Myoclonus of Peripheral Origin : Two Case Reports
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	Movement Disorders (revue)
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Movement Disorders (revue)

Myoclonus of Peripheral Origin : Two Case Reports

Myoclonus of Peripheral Origin : Two Case Reports

Source :

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Abstract

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