MovDisordV3, PascalFrancis, Checkpoint, bibRecord, 000B41

Comparing Exercise in Parkinson's Disease-The Berlin LSVT®BIG Study

Identifieur interne : 000B41 ( PascalFrancis/Checkpoint ); précédent : 000B40; suivant : 000B42

Comparing Exercise in Parkinson's Disease-The Berlin LSVT®BIG Study

Auteurs : Georg Ebersbach [Allemagne] ; Almut Ebersbach [Allemagne] ; Daniela Edler [Allemagne] ; Olaf Kaufhold [Allemagne] ; Matthias Kusch [Allemagne] ; Andreas Kupsch [Allemagne] ; Jörg Wissel [Allemagne]

Source :

Movement disorders [ 0885-3185 ] ; 2010.

RBID : Pascal:10-0446314

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Pathologie du système nerveux, Exercice physique, Marche à pied, Physiothérapie.

English descriptors

KwdEn :
- Nervous system diseases, Parkinson disease, Physical exercise, Physiotherapy, Walking.

Abstract

Physiotherapy is widely used in Parkinson's disease (PD), but there are few controlled studies comparing active interventions. Recently, a technique named "LSYT®BIG" has been introduced. LSVT®BIG is derived from the Lee Silverman Voice Treatment and focuses on intensive exercising of high-amplitude movements. In the present comparative study, 60 patients with mild to moderate PD were randomly assigned to receive either one-to-one training (BIG), group training of Nordic Walking (WALK), or domestic nonsupervised exercises (HOME). Patients in training (BIG) and WALK received 16 hours of supervised training within 4 (BIG) or 8 (WALK) weeks. The primary efficacy measure was difference in change in Unified Parkinson's Disease Rating Scale (UPDRS) motor score from baseline to follow-up at 16 weeks between groups. UPDRS scores were obtained by blinded video rating. ANCOVA showed significant group differences for UPDRS-motor score at final assessment (P < 0.001). Mean improvement of UPDRS in BIG was -5.05 (SD 3.91) whereas there was a mild deterioration of 0.58 (SD 3.17) in WALK and of 1.68 (SD 5.95) in HOME. LSVT®BIG was also superior to WALK and HOME in timed-up-and-go and timed 10 m walking. There were no significant group differences for quality of life (PDQ39). These results provide evidence that LSVT®BIG is an effective technique to improve motor performance in patients with PD.

Affiliations:

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<front><div type="abstract" xml:lang="en">Physiotherapy is widely used in Parkinson's disease (PD), but there are few controlled studies comparing active interventions. Recently, a technique named "LSYT®BIG" has been introduced. LSVT®BIG is derived from the Lee Silverman Voice Treatment and focuses on intensive exercising of high-amplitude movements. In the present comparative study, 60 patients with mild to moderate PD were randomly assigned to receive either one-to-one training (BIG), group training of Nordic Walking (WALK), or domestic nonsupervised exercises (HOME). Patients in training (BIG) and WALK received 16 hours of supervised training within 4 (BIG) or 8 (WALK) weeks. The primary efficacy measure was difference in change in Unified Parkinson's Disease Rating Scale (UPDRS) motor score from baseline to follow-up at 16 weeks between groups. UPDRS scores were obtained by blinded video rating. ANCOVA showed significant group differences for UPDRS-motor score at final assessment (P < 0.001). Mean improvement of UPDRS in BIG was -5.05 (SD 3.91) whereas there was a mild deterioration of 0.58 (SD 3.17) in WALK and of 1.68 (SD 5.95) in HOME. LSVT®BIG was also superior to WALK and HOME in timed-up-and-go and timed 10 m walking. There were no significant group differences for quality of life (PDQ39). These results provide evidence that LSVT®BIG is an effective technique to improve motor performance in patients with PD.</div>
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<fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Locomotion</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Locomotion</s0>
<s5>42</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Locomoción</s0>
<s5>42</s5>
</fC07>
<fN21><s1>291</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations><list><country><li>Allemagne</li>
</country>
<region><li>Berlin</li>
</region>
<settlement><li>Berlin</li>
</settlement>
</list>
<tree><country name="Allemagne"><noRegion><name sortKey="Ebersbach, Georg" sort="Ebersbach, Georg" uniqKey="Ebersbach G" first="Georg" last="Ebersbach">Georg Ebersbach</name>
</noRegion>
<name sortKey="Ebersbach, Almut" sort="Ebersbach, Almut" uniqKey="Ebersbach A" first="Almut" last="Ebersbach">Almut Ebersbach</name>
<name sortKey="Edler, Daniela" sort="Edler, Daniela" uniqKey="Edler D" first="Daniela" last="Edler">Daniela Edler</name>
<name sortKey="Kaufhold, Olaf" sort="Kaufhold, Olaf" uniqKey="Kaufhold O" first="Olaf" last="Kaufhold">Olaf Kaufhold</name>
<name sortKey="Kupsch, Andreas" sort="Kupsch, Andreas" uniqKey="Kupsch A" first="Andreas" last="Kupsch">Andreas Kupsch</name>
<name sortKey="Kusch, Matthias" sort="Kusch, Matthias" uniqKey="Kusch M" first="Matthias" last="Kusch">Matthias Kusch</name>
<name sortKey="Wissel, Jorg" sort="Wissel, Jorg" uniqKey="Wissel J" first="Jörg" last="Wissel">Jörg Wissel</name>
</country>
</tree>
</affiliations>
</record>

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	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Comparing Exercise in Parkinson's Disease-The Berlin LSVT®BIG Study

Comparing Exercise in Parkinson's Disease-The Berlin LSVT®BIG Study

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