Photophobia in Essential Blepharospasm-A Positron Emission Tomographic Study
Identifieur interne : 000903 ( PascalFrancis/Checkpoint ); précédent : 000902; suivant : 000904Photophobia in Essential Blepharospasm-A Positron Emission Tomographic Study
Auteurs : Hirofumi Emoto [Japon] ; Yukihisa Suzuki [Japon] ; Masato Wakakura [Japon] ; Chiharu Horie [Japon] ; Motohiro Kiyosawa [Japon] ; Manabu Mochizuki [Japon] ; Keiichi Kawasaki [Japon] ; Keiichi Oda [Japon] ; Kiichi Ishiwata [Japon] ; Kenji Ishii [Japon]Source :
- Movement disorders [ 0885-3185 ] ; 2010.
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Abstract
To localize regional alterations in cerebral glucose metabolism in essential blepharospasm (EB) patients with photophobia. We have studied 22 EB patients by performing positron emission tomography and [18F]-fluorodeoxyglucose analysis. The patients were classified into two subgroups, namely, EB with photophobia (P group) and EB without photophobia (NP group), and compared with a healthy control group (n = 44). There were no significant differences between the two patient groups with respect to the severity of motor symptoms or the duration for which the condition persisted. The FDG-PET images were analyzed using the statistical parametric mapping software. As compared to the control group, the P group exhibited significant hypermetabolism in the thalamus (P = 0.002), while the NP group exhibited significant hypometabolism in the dorsal midbrain, especially, in the superior colliculus (P = 0.005). The P group exhibited significant hypermetabolism in the thalamus and the dorsal midbrain as compared to the NP group (P < 0.001). These findings suggest that photophobia in EB patients may be associated with abnormal hyperactivity in the thalamus. Either hyperactivity of the thalamus or hypoactivity of the superior colliculus, or both may be associated with excessive blinking in these patients.
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Manabu" sort="Mochizuki, Manabu" uniqKey="Mochizuki M" first="Manabu" last="Mochizuki">Manabu Mochizuki</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Kawasaki, Keiichi" sort="Kawasaki, Keiichi" uniqKey="Kawasaki K" first="Keiichi" last="Kawasaki">Keiichi Kawasaki</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Oda, Keiichi" sort="Oda, Keiichi" uniqKey="Oda K" first="Keiichi" last="Oda">Keiichi Oda</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Ishiwata, Kiichi" sort="Ishiwata, Kiichi" uniqKey="Ishiwata K" first="Kiichi" last="Ishiwata">Kiichi Ishiwata</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 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type="wicri:Area/PascalFrancis/Checkpoint">000903</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Photophobia in Essential Blepharospasm-A Positron Emission Tomographic Study</title><author><name sortKey="Emoto, Hirofumi" sort="Emoto, Hirofumi" uniqKey="Emoto H" first="Hirofumi" last="Emoto">Hirofumi Emoto</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Suzuki, Yukihisa" sort="Suzuki, Yukihisa" uniqKey="Suzuki Y" first="Yukihisa" last="Suzuki">Yukihisa Suzuki</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Wakakura, Masato" sort="Wakakura, Masato" uniqKey="Wakakura M" first="Masato" last="Wakakura">Masato Wakakura</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Neuro-Ophthalmology, Inouye Eye Hospital</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>3 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Horie, Chiharu" sort="Horie, Chiharu" uniqKey="Horie C" first="Chiharu" last="Horie">Chiharu Horie</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Kiyosawa, Motohiro" sort="Kiyosawa, Motohiro" uniqKey="Kiyosawa M" first="Motohiro" last="Kiyosawa">Motohiro Kiyosawa</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Mochizuki, Manabu" sort="Mochizuki, Manabu" uniqKey="Mochizuki M" first="Manabu" last="Mochizuki">Manabu Mochizuki</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Kawasaki, Keiichi" sort="Kawasaki, Keiichi" uniqKey="Kawasaki K" first="Keiichi" last="Kawasaki">Keiichi Kawasaki</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Oda, Keiichi" sort="Oda, Keiichi" uniqKey="Oda K" first="Keiichi" last="Oda">Keiichi Oda</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Ishiwata, Kiichi" sort="Ishiwata, Kiichi" uniqKey="Ishiwata K" first="Kiichi" last="Ishiwata">Kiichi Ishiwata</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Ishii, Kenji" sort="Ishii, Kenji" uniqKey="Ishii K" first="Kenji" last="Ishii">Kenji Ishii</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Blepharospasm</term><term>Colliculus superior</term><term>Emission tomography</term><term>Nervous system diseases</term><term>Positron</term><term>Positron emission tomography</term><term>Thalamus</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Blépharospasme</term><term>Pathologie du système nerveux</term><term>Positon</term><term>Tomographie par émission de positons</term><term>Tomoscintigraphie</term><term>Thalamus</term><term>Tubercule quadrijumeau antérieur</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To localize regional alterations in cerebral glucose metabolism in essential blepharospasm (EB) patients with photophobia. We have studied 22 EB patients by performing positron emission tomography and [<sup>18</sup>F]-fluorodeoxyglucose analysis. The patients were classified into two subgroups, namely, EB with photophobia (P group) and EB without photophobia (NP group), and compared with a healthy control group (n = 44). There were no significant differences between the two patient groups with respect to the severity of motor symptoms or the duration for which the condition persisted. The FDG-PET images were analyzed using the statistical parametric mapping software. As compared to the control group, the P group exhibited significant hypermetabolism in the thalamus (P = 0.002), while the NP group exhibited significant hypometabolism in the dorsal midbrain, especially, in the superior colliculus (P = 0.005). The P group exhibited significant hypermetabolism in the thalamus and the dorsal midbrain as compared to the NP group (P < 0.001). These findings suggest that photophobia in EB patients may be associated with abnormal hyperactivity in the thalamus. Either hyperactivity of the thalamus or hypoactivity of the superior colliculus, or both may be associated with excessive blinking in these patients.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0></fA01><fA03 i2="1"><s0>Mov. disord.</s0></fA03><fA05><s2>25</s2></fA05><fA06><s2>4</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Photophobia in Essential Blepharospasm-A Positron Emission Tomographic Study</s1></fA08><fA11 i1="01" i2="1"><s1>EMOTO (Hirofumi)</s1></fA11><fA11 i1="02" i2="1"><s1>SUZUKI (Yukihisa)</s1></fA11><fA11 i1="03" i2="1"><s1>WAKAKURA (Masato)</s1></fA11><fA11 i1="04" i2="1"><s1>HORIE (Chiharu)</s1></fA11><fA11 i1="05" i2="1"><s1>KIYOSAWA (Motohiro)</s1></fA11><fA11 i1="06" i2="1"><s1>MOCHIZUKI (Manabu)</s1></fA11><fA11 i1="07" i2="1"><s1>KAWASAKI (Keiichi)</s1></fA11><fA11 i1="08" i2="1"><s1>ODA (Keiichi)</s1></fA11><fA11 i1="09" i2="1"><s1>ISHIWATA (Kiichi)</s1></fA11><fA11 i1="10" i2="1"><s1>ISHII (Kenji)</s1></fA11><fA14 i1="01"><s1>Positron Medical Center, Tokyo Metropolitan Institute of Gerontology</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>7 aut.</sZ><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></fA14><fA14 i1="02"><s1>Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></fA14><fA14 i1="03"><s1>Department of Neuro-Ophthalmology, Inouye Eye Hospital</s1><s2>Tokyo</s2><s3>JPN</s3><sZ>3 aut.</sZ></fA14><fA20><s1>433-439</s1></fA20><fA21><s1>2010</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20953</s2><s5>354000181523490060</s5></fA43><fA44><s0>0000</s0><s1>© 2010 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>27 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>10-0178213</s0></fA47><fA60><s1>P</s1></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Movement disorders</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>To localize regional alterations in cerebral glucose metabolism in essential blepharospasm (EB) patients with photophobia. We have studied 22 EB patients by performing positron emission tomography and [<sup>18</sup>F]-fluorodeoxyglucose analysis. The patients were classified into two subgroups, namely, EB with photophobia (P group) and EB without photophobia (NP group), and compared with a healthy control group (n = 44). There were no significant differences between the two patient groups with respect to the severity of motor symptoms or the duration for which the condition persisted. The FDG-PET images were analyzed using the statistical parametric mapping software. As compared to the control group, the P group exhibited significant hypermetabolism in the thalamus (P = 0.002), while the NP group exhibited significant hypometabolism in the dorsal midbrain, especially, in the superior colliculus (P = 0.005). The P group exhibited significant hypermetabolism in the thalamus and the dorsal midbrain as compared to the NP group (P < 0.001). These findings suggest that photophobia in EB patients may be associated with abnormal hyperactivity in the thalamus. Either hyperactivity of the thalamus or hypoactivity of the superior colliculus, or both may be associated with excessive blinking in these patients.</s0></fC01><fC02 i1="01" i2="X"><s0>002B17</s0></fC02><fC02 i1="02" i2="X"><s0>002B24B07</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Blépharospasme</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Blepharospasm</s0><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Blefaroespasmo</s0><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Pathologie du système nerveux</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Nervous system diseases</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Sistema nervioso patología</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Positon</s0><s5>09</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Positron</s0><s5>09</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Positrón</s0><s5>09</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Tomographie par émission de positons</s0><s5>10</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Positron emission tomography</s0><s5>10</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Tomografía emisión positrones</s0><s5>10</s5></fC03><fC03 i1="05" i2="X" l="FRE"><s0>Tomoscintigraphie</s0><s5>11</s5></fC03><fC03 i1="05" i2="X" l="ENG"><s0>Emission tomography</s0><s5>11</s5></fC03><fC03 i1="05" i2="X" l="SPA"><s0>Tomocentelleografía</s0><s5>11</s5></fC03><fC03 i1="06" i2="X" l="FRE"><s0>Thalamus</s0><s5>12</s5></fC03><fC03 i1="06" i2="X" l="ENG"><s0>Thalamus</s0><s5>12</s5></fC03><fC03 i1="06" i2="X" l="SPA"><s0>Tálamo</s0><s5>12</s5></fC03><fC03 i1="07" i2="X" l="FRE"><s0>Tubercule quadrijumeau antérieur</s0><s5>13</s5></fC03><fC03 i1="07" i2="X" l="ENG"><s0>Colliculus superior</s0><s5>13</s5></fC03><fC03 i1="07" i2="X" l="SPA"><s0>Tubérculo cuadrigémino anterior</s0><s5>13</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Pathologie de l'oeil</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Eye disease</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Ojo patología</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Pathologie de la paupière</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Eyelid disease</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Párpado patología</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Encéphale</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Encephalon</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Encéfalo</s0><s5>39</s5></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Système nerveux central</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervioso central</s0><s5>40</s5></fC07><fC07 i1="05" i2="X" l="FRE"><s0>Voie visuelle</s0><s5>41</s5></fC07><fC07 i1="05" i2="X" l="ENG"><s0>Visual pathway</s0><s5>41</s5></fC07><fC07 i1="05" i2="X" l="SPA"><s0>Vía visual</s0><s5>41</s5></fC07><fN21><s1>116</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist><affiliations><list><country><li>Japon</li></country><settlement><li>Tokyo</li></settlement></list><tree><country name="Japon"><noRegion><name sortKey="Emoto, Hirofumi" sort="Emoto, Hirofumi" uniqKey="Emoto H" first="Hirofumi" last="Emoto">Hirofumi Emoto</name></noRegion><name sortKey="Emoto, Hirofumi" sort="Emoto, Hirofumi" uniqKey="Emoto H" first="Hirofumi" last="Emoto">Hirofumi Emoto</name><name sortKey="Horie, Chiharu" sort="Horie, Chiharu" uniqKey="Horie C" first="Chiharu" last="Horie">Chiharu Horie</name><name sortKey="Horie, Chiharu" sort="Horie, Chiharu" uniqKey="Horie C" first="Chiharu" last="Horie">Chiharu Horie</name><name sortKey="Ishii, Kenji" sort="Ishii, Kenji" uniqKey="Ishii K" first="Kenji" last="Ishii">Kenji Ishii</name><name sortKey="Ishiwata, Kiichi" sort="Ishiwata, Kiichi" uniqKey="Ishiwata K" first="Kiichi" last="Ishiwata">Kiichi Ishiwata</name><name sortKey="Kawasaki, Keiichi" sort="Kawasaki, Keiichi" uniqKey="Kawasaki K" first="Keiichi" last="Kawasaki">Keiichi Kawasaki</name><name sortKey="Kiyosawa, Motohiro" sort="Kiyosawa, Motohiro" uniqKey="Kiyosawa M" first="Motohiro" last="Kiyosawa">Motohiro Kiyosawa</name><name sortKey="Mochizuki, Manabu" sort="Mochizuki, Manabu" uniqKey="Mochizuki M" first="Manabu" last="Mochizuki">Manabu Mochizuki</name><name sortKey="Oda, Keiichi" sort="Oda, Keiichi" uniqKey="Oda K" first="Keiichi" last="Oda">Keiichi Oda</name><name sortKey="Suzuki, Yukihisa" sort="Suzuki, Yukihisa" uniqKey="Suzuki Y" first="Yukihisa" last="Suzuki">Yukihisa Suzuki</name><name sortKey="Suzuki, Yukihisa" sort="Suzuki, Yukihisa" uniqKey="Suzuki Y" first="Yukihisa" last="Suzuki">Yukihisa Suzuki</name><name sortKey="Wakakura, Masato" sort="Wakakura, Masato" uniqKey="Wakakura M" first="Masato" last="Wakakura">Masato Wakakura</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= Photophobia in Essential Blepharospasm-A Positron Emission Tomographic Study
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