Unilateral Lower Limb Rest Tremor is not Necessarily a Presenting Symptom of Parkinson's Disease
Identifieur interne : 000762 ( PascalFrancis/Checkpoint ); précédent : 000761; suivant : 000763Unilateral Lower Limb Rest Tremor is not Necessarily a Presenting Symptom of Parkinson's Disease
Auteurs : Mark A. Hellmann [Israël] ; Eldad Melamed [Israël] ; Adam P. Steinmetz [Israël] ; Ruth Djaldetti [Israël]Source :
- Movement disorders [ 0885-3185 ] ; 2010.
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- Pascal (Inist)
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- KwdEn :
Abstract
Lower leg rest tremor is an uncommon symptom of neurological disease. Review of the files of 16 patients who presented with lower leg tremor (average age 58 ± 16 years; average disease duration 6.8 ± 8.5 years) yielded a diagnosis of Parkinson's disease (PD) in 5 and probable multiple system atrophy (MSA) in 3. In 4 patients with an indeterminate diagnosis, cardiac MIBG SPECT was positive in 3, indicating PD, and negative in one, suggesting MSA. Two patients each had psychogenic tremor and drug-induced parkinsonism. Although lower leg tremor is considered an unusual presentation of PD, it should raise suspicions of MSA and other neurodegenerative disorders.
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<front><div type="abstract" xml:lang="en">Lower leg rest tremor is an uncommon symptom of neurological disease. Review of the files of 16 patients who presented with lower leg tremor (average age 58 ± 16 years; average disease duration 6.8 ± 8.5 years) yielded a diagnosis of Parkinson's disease (PD) in 5 and probable multiple system atrophy (MSA) in 3. In 4 patients with an indeterminate diagnosis, cardiac MIBG SPECT was positive in 3, indicating PD, and negative in one, suggesting MSA. Two patients each had psychogenic tremor and drug-induced parkinsonism. Although lower leg tremor is considered an unusual presentation of PD, it should raise suspicions of MSA and other neurodegenerative disorders.</div>
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