Is Transcranial Sonography Useful to Distinguish Scans Without Evidence of Dopaminergic Deficit Patients From Parkinson's Disease?
Identifieur interne : 000152 ( PascalFrancis/Checkpoint ); précédent : 000151; suivant : 000153Is Transcranial Sonography Useful to Distinguish Scans Without Evidence of Dopaminergic Deficit Patients From Parkinson's Disease?
Auteurs : Heike Stockner [Autriche] ; Petra Schwingenschuh [Royaume-Uni, Autriche] ; Atbin Djamshidian [Royaume-Uni] ; Laura Silveira-Moriyama [Royaume-Uni] ; Petra Katschnig [Royaume-Uni, Autriche] ; Klaus Seppi [Autriche] ; John Dickson [Royaume-Uni] ; Mark J. Edwards [Royaume-Uni] ; Andrew Lees (neurologue) [Royaume-Uni] ; Werner Poewe [Autriche] ; Kailash P. Bhatia [Royaume-Uni]Source :
- Movement disorders [ 0885-3185 ] ; 2012.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
Background: Approximately 10% of patients clinically diagnosed with early Parkinson's disease (PD) subsequently have normal dopaminergic functional imaging. Transcranial sonography (TCS) has been shown to detect midbrain hyperechogenicity in approximately 90% of Parkinson's disease (PD) patients and 10% of the healthy population. The aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (SWEDD), in comparison to PD patients. Methods: TCS was performed in 14 patients with SWEDD and 19 PD patients. Results: There was a significantly increased area of echogenicity in the PD group (0.24 ± 0.06 cm2), compared to the group of patients with SWEDD (0.13 ± 0.06 cm2; P < 0.001). One (9.1%) of these patients, compared to 14 (82.5%) of the PD patients, was found to have hyperechogenicity (P < 0.001). Conclusions: We conclude that TCS is useful to distinguish PD patients from patients with suspected parkinsonism and SWEDD.
Affiliations:
- Autriche, Royaume-Uni
- Angleterre, Grand Londres, Tyrol (Land)
- Innsbruck, Londres
- National Hospital for Neurology and Neurosurgery, Université de médecine d'Innsbruck
Links toward previous steps (curation, corpus...)
Links to Exploration step
Pascal:12-0339944Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Is Transcranial Sonography Useful to Distinguish Scans Without Evidence of Dopaminergic Deficit Patients From Parkinson's Disease?</title><author><name sortKey="Stockner, Heike" sort="Stockner, Heike" uniqKey="Stockner H" first="Heike" last="Stockner">Heike Stockner</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Medical University Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Schwingenschuh, Petra" sort="Schwingenschuh, Petra" uniqKey="Schwingenschuh P" first="Petra" last="Schwingenschuh">Petra Schwingenschuh</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurology, Division of Special Neurology, Medical University of Graz</s1><s2>Graz</s2><s3>AUT</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Djamshidian, Atbin" sort="Djamshidian, Atbin" uniqKey="Djamshidian A" first="Atbin" last="Djamshidian">Atbin Djamshidian</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Reta Lila Weston Institute of Neurological Studies, UCL, Institute of Neurology</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Silveira Moriyama, Laura" sort="Silveira Moriyama, Laura" uniqKey="Silveira Moriyama L" first="Laura" last="Silveira-Moriyama">Laura Silveira-Moriyama</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Reta Lila Weston Institute of Neurological Studies, UCL, Institute of Neurology</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Katschnig, Petra" sort="Katschnig, Petra" uniqKey="Katschnig P" first="Petra" last="Katschnig">Petra Katschnig</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurology, Division of Special Neurology, Medical University of Graz</s1><s2>Graz</s2><s3>AUT</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Medical University Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Dickson, John" sort="Dickson, John" uniqKey="Dickson J" first="John" last="Dickson">John Dickson</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Institute of Nuclear Medicine, UCL</s1><s2>London</s2><s3>GBR</s3><sZ>7 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Edwards, Mark J" sort="Edwards, Mark J" uniqKey="Edwards M" first="Mark J." last="Edwards">Mark J. Edwards</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Reta Lila Weston Institute of Neurological Studies, UCL, Institute of Neurology</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName>National Hospital for Neurology and Neurosurgery</orgName></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Medical University Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Innsbruck</wicri:noRegion><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName></affiliation></author><author><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P." last="Bhatia">Kailash P. Bhatia</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">12-0339944</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 12-0339944 INIST</idno><idno type="RBID">Pascal:12-0339944</idno><idno type="wicri:Area/PascalFrancis/Corpus">000118</idno><idno type="wicri:Area/PascalFrancis/Curation">002B96</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000152</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Is Transcranial Sonography Useful to Distinguish Scans Without Evidence of Dopaminergic Deficit Patients From Parkinson's Disease?</title><author><name sortKey="Stockner, Heike" sort="Stockner, Heike" uniqKey="Stockner H" first="Heike" last="Stockner">Heike Stockner</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Medical University Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Schwingenschuh, Petra" sort="Schwingenschuh, Petra" uniqKey="Schwingenschuh P" first="Petra" last="Schwingenschuh">Petra Schwingenschuh</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurology, Division of Special Neurology, Medical University of Graz</s1><s2>Graz</s2><s3>AUT</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Djamshidian, Atbin" sort="Djamshidian, Atbin" uniqKey="Djamshidian A" first="Atbin" last="Djamshidian">Atbin Djamshidian</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Reta Lila Weston Institute of Neurological Studies, UCL, Institute of Neurology</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Silveira Moriyama, Laura" sort="Silveira Moriyama, Laura" uniqKey="Silveira Moriyama L" first="Laura" last="Silveira-Moriyama">Laura Silveira-Moriyama</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Reta Lila Weston Institute of Neurological Studies, UCL, Institute of Neurology</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Katschnig, Petra" sort="Katschnig, Petra" uniqKey="Katschnig P" first="Petra" last="Katschnig">Petra Katschnig</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Neurology, Division of Special Neurology, Medical University of Graz</s1><s2>Graz</s2><s3>AUT</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Medical University Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Dickson, John" sort="Dickson, John" uniqKey="Dickson J" first="John" last="Dickson">John Dickson</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Institute of Nuclear Medicine, UCL</s1><s2>London</s2><s3>GBR</s3><sZ>7 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Edwards, Mark J" sort="Edwards, Mark J" uniqKey="Edwards M" first="Mark J." last="Edwards">Mark J. Edwards</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Reta Lila Weston Institute of Neurological Studies, UCL, Institute of Neurology</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName>National Hospital for Neurology and Neurosurgery</orgName></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Medical University Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Autriche</country><wicri:noRegion>Innsbruck</wicri:noRegion><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName></affiliation></author><author><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P." last="Bhatia">Kailash P. Bhatia</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Human</term><term>Nervous system diseases</term><term>Parkinson disease</term><term>Sonography</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term><term>Pathologie du système nerveux</term><term>Exploration ultrason</term><term>Homme</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Approximately 10% of patients clinically diagnosed with early Parkinson's disease (PD) subsequently have normal dopaminergic functional imaging. Transcranial sonography (TCS) has been shown to detect midbrain hyperechogenicity in approximately 90% of Parkinson's disease (PD) patients and 10% of the healthy population. The aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (SWEDD), in comparison to PD patients. Methods: TCS was performed in 14 patients with SWEDD and 19 PD patients. Results: There was a significantly increased area of echogenicity in the PD group (0.24 ± 0.06 cm<sup>2</sup>), compared to the group of patients with SWEDD (0.13 ± 0.06 cm<sup>2</sup>; P < 0.001). One (9.1%) of these patients, compared to 14 (82.5%) of the PD patients, was found to have hyperechogenicity (P < 0.001). Conclusions: We conclude that TCS is useful to distinguish PD patients from patients with suspected parkinsonism and SWEDD.</div></front></TEI><inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0885-3185</s0></fA01><fA03 i2="1"><s0>Mov. disord.</s0></fA03><fA05><s2>27</s2></fA05><fA06><s2>9</s2></fA06><fA08 i1="01" i2="1" l="ENG"><s1>Is Transcranial Sonography Useful to Distinguish Scans Without Evidence of Dopaminergic Deficit Patients From Parkinson's Disease?</s1></fA08><fA11 i1="01" i2="1"><s1>STOCKNER (Heike)</s1></fA11><fA11 i1="02" i2="1"><s1>SCHWINGENSCHUH (Petra)</s1></fA11><fA11 i1="03" i2="1"><s1>DJAMSHIDIAN (Atbin)</s1></fA11><fA11 i1="04" i2="1"><s1>SILVEIRA-MORIYAMA (Laura)</s1></fA11><fA11 i1="05" i2="1"><s1>KATSCHNIG (Petra)</s1></fA11><fA11 i1="06" i2="1"><s1>SEPPI (Klaus)</s1></fA11><fA11 i1="07" i2="1"><s1>DICKSON (John)</s1></fA11><fA11 i1="08" i2="1"><s1>EDWARDS (Mark J.)</s1></fA11><fA11 i1="09" i2="1"><s1>LEES (Andrew J.)</s1></fA11><fA11 i1="10" i2="1"><s1>POEWE (Werner)</s1></fA11><fA11 i1="11" i2="1"><s1>BHATIA (Kailash P.)</s1></fA11><fA14 i1="01"><s1>Department of Neurology, Medical University Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>1 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></fA14><fA14 i1="02"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London (UCL)</s1><s2>London</s2><s3>GBR</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ><sZ>11 aut.</sZ></fA14><fA14 i1="03"><s1>Department of Neurology, Division of Special Neurology, Medical University of Graz</s1><s2>Graz</s2><s3>AUT</s3><sZ>2 aut.</sZ><sZ>5 aut.</sZ></fA14><fA14 i1="04"><s1>Reta Lila Weston Institute of Neurological Studies, UCL, Institute of Neurology</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>9 aut.</sZ></fA14><fA14 i1="05"><s1>Institute of Nuclear Medicine, UCL</s1><s2>London</s2><s3>GBR</s3><sZ>7 aut.</sZ></fA14><fA20><s1>1180-1183</s1></fA20><fA21><s1>2012</s1></fA21><fA23 i1="01"><s0>ENG</s0></fA23><fA43 i1="01"><s1>INIST</s1><s2>20953</s2><s5>354000504065380220</s5></fA43><fA44><s0>0000</s0><s1>© 2012 INIST-CNRS. All rights reserved.</s1></fA44><fA45><s0>25 ref.</s0></fA45><fA47 i1="01" i2="1"><s0>12-0339944</s0></fA47><fA60><s1>P</s1><s3>CC</s3></fA60><fA61><s0>A</s0></fA61><fA64 i1="01" i2="1"><s0>Movement disorders</s0></fA64><fA66 i1="01"><s0>USA</s0></fA66><fC01 i1="01" l="ENG"><s0>Background: Approximately 10% of patients clinically diagnosed with early Parkinson's disease (PD) subsequently have normal dopaminergic functional imaging. Transcranial sonography (TCS) has been shown to detect midbrain hyperechogenicity in approximately 90% of Parkinson's disease (PD) patients and 10% of the healthy population. The aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (SWEDD), in comparison to PD patients. Methods: TCS was performed in 14 patients with SWEDD and 19 PD patients. Results: There was a significantly increased area of echogenicity in the PD group (0.24 ± 0.06 cm<sup>2</sup>), compared to the group of patients with SWEDD (0.13 ± 0.06 cm<sup>2</sup>; P < 0.001). One (9.1%) of these patients, compared to 14 (82.5%) of the PD patients, was found to have hyperechogenicity (P < 0.001). Conclusions: We conclude that TCS is useful to distinguish PD patients from patients with suspected parkinsonism and SWEDD.</s0></fC01><fC02 i1="01" i2="X"><s0>002B17</s0></fC02><fC02 i1="02" i2="X"><s0>002B17G</s0></fC02><fC03 i1="01" i2="X" l="FRE"><s0>Maladie de Parkinson</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="ENG"><s0>Parkinson disease</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="01" i2="X" l="SPA"><s0>Parkinson enfermedad</s0><s2>NM</s2><s5>01</s5></fC03><fC03 i1="02" i2="X" l="FRE"><s0>Pathologie du système nerveux</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="ENG"><s0>Nervous system diseases</s0><s5>02</s5></fC03><fC03 i1="02" i2="X" l="SPA"><s0>Sistema nervioso patología</s0><s5>02</s5></fC03><fC03 i1="03" i2="X" l="FRE"><s0>Exploration ultrason</s0><s5>09</s5></fC03><fC03 i1="03" i2="X" l="ENG"><s0>Sonography</s0><s5>09</s5></fC03><fC03 i1="03" i2="X" l="SPA"><s0>Exploración ultrasonido</s0><s5>09</s5></fC03><fC03 i1="04" i2="X" l="FRE"><s0>Homme</s0><s5>10</s5></fC03><fC03 i1="04" i2="X" l="ENG"><s0>Human</s0><s5>10</s5></fC03><fC03 i1="04" i2="X" l="SPA"><s0>Hombre</s0><s5>10</s5></fC03><fC07 i1="01" i2="X" l="FRE"><s0>Pathologie de l'encéphale</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="ENG"><s0>Cerebral disorder</s0><s5>37</s5></fC07><fC07 i1="01" i2="X" l="SPA"><s0>Encéfalo patología</s0><s5>37</s5></fC07><fC07 i1="02" i2="X" l="FRE"><s0>Syndrome extrapyramidal</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0><s5>38</s5></fC07><fC07 i1="02" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0><s5>38</s5></fC07><fC07 i1="03" i2="X" l="FRE"><s0>Maladie dégénérative</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="ENG"><s0>Degenerative disease</s0><s5>39</s5></fC07><fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0><s5>39</s5></fC07><fC07 i1="04" i2="X" l="FRE"><s0>Pathologie du système nerveux central</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="ENG"><s0>Central nervous system disease</s0><s5>40</s5></fC07><fC07 i1="04" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0><s5>40</s5></fC07><fN21><s1>261</s1></fN21><fN44 i1="01"><s1>OTO</s1></fN44><fN82><s1>OTO</s1></fN82></pA></standard></inist><affiliations><list><country><li>Autriche</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li><li>Tyrol (Land)</li></region><settlement><li>Innsbruck</li><li>Londres</li></settlement><orgName><li>National Hospital for Neurology and Neurosurgery</li><li>Université de médecine d'Innsbruck</li></orgName></list><tree><country name="Autriche"><noRegion><name sortKey="Stockner, Heike" sort="Stockner, Heike" uniqKey="Stockner H" first="Heike" last="Stockner">Heike Stockner</name></noRegion><name sortKey="Katschnig, Petra" sort="Katschnig, Petra" uniqKey="Katschnig P" first="Petra" last="Katschnig">Petra Katschnig</name><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><name sortKey="Schwingenschuh, Petra" sort="Schwingenschuh, Petra" uniqKey="Schwingenschuh P" first="Petra" last="Schwingenschuh">Petra Schwingenschuh</name><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Schwingenschuh, Petra" sort="Schwingenschuh, Petra" uniqKey="Schwingenschuh P" first="Petra" last="Schwingenschuh">Petra Schwingenschuh</name></region><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P." last="Bhatia">Kailash P. Bhatia</name><name sortKey="Dickson, John" sort="Dickson, John" uniqKey="Dickson J" first="John" last="Dickson">John Dickson</name><name sortKey="Djamshidian, Atbin" sort="Djamshidian, Atbin" uniqKey="Djamshidian A" first="Atbin" last="Djamshidian">Atbin Djamshidian</name><name sortKey="Edwards, Mark J" sort="Edwards, Mark J" uniqKey="Edwards M" first="Mark J." last="Edwards">Mark J. Edwards</name><name sortKey="Katschnig, Petra" sort="Katschnig, Petra" uniqKey="Katschnig P" first="Petra" last="Katschnig">Petra Katschnig</name><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name><name sortKey="Silveira Moriyama, Laura" sort="Silveira Moriyama, Laura" uniqKey="Silveira Moriyama L" first="Laura" last="Silveira-Moriyama">Laura Silveira-Moriyama</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/PascalFrancis/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000152 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Checkpoint/biblio.hfd -nk 000152 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= PascalFrancis
|étape= Checkpoint
|type= RBID
|clé= Pascal:12-0339944
|texte= Is Transcranial Sonography Useful to Distinguish Scans Without Evidence of Dopaminergic Deficit Patients From Parkinson's Disease?
}}
| This area was generated with Dilib version V0.6.23. |  |