Retinal pathology detected by optical coherence tomography in an animal model of Parkinson's disease.
Identifieur interne : 004064 ( Ncbi/Merge ); précédent : 004063; suivant : 004065Retinal pathology detected by optical coherence tomography in an animal model of Parkinson's disease.
Auteurs : Jay S. Schneider [États-Unis] ; Mark E. Ault ; David W. AndersonSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
Abstract
Optical coherence tomography (OCT) is a noninvasive procedure for analysis of retinal morphology. Significant changes in the thickness of the peripapillary retinal nerve fiber layer (RNFL) in Parkinson's disease (PD) have been reported, and the current study was performed to examine whether such changes can also be detected in an animal model of PD.
DOI: 10.1002/mds.25974
PubMed: 25070726
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000439
- to stream PubMed, to step Curation: 000439
- to stream PubMed, to step Checkpoint: 000430
Links to Exploration step
pubmed:25070726Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Retinal pathology detected by optical coherence tomography in an animal model of Parkinson's disease.</title><author><name sortKey="Schneider, Jay S" sort="Schneider, Jay S" uniqKey="Schneider J" first="Jay S" last="Schneider">Jay S. Schneider</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Ault, Mark E" sort="Ault, Mark E" uniqKey="Ault M" first="Mark E" last="Ault">Mark E. Ault</name></author><author><name sortKey="Anderson, David W" sort="Anderson, David W" uniqKey="Anderson D" first="David W" last="Anderson">David W. Anderson</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:25070726</idno><idno type="pmid">25070726</idno><idno type="doi">10.1002/mds.25974</idno><idno type="wicri:Area/PubMed/Corpus">000439</idno><idno type="wicri:Area/PubMed/Curation">000439</idno><idno type="wicri:Area/PubMed/Checkpoint">000430</idno><idno type="wicri:Area/Ncbi/Merge">004064</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Retinal pathology detected by optical coherence tomography in an animal model of Parkinson's disease.</title><author><name sortKey="Schneider, Jay S" sort="Schneider, Jay S" uniqKey="Schneider J" first="Jay S" last="Schneider">Jay S. Schneider</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Ault, Mark E" sort="Ault, Mark E" uniqKey="Ault M" first="Mark E" last="Ault">Mark E. Ault</name></author><author><name sortKey="Anderson, David W" sort="Anderson, David W" uniqKey="Anderson D" first="David W" last="Anderson">David W. Anderson</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Disease Models, Animal</term><term>MPTP Poisoning (pathology)</term><term>Macaca fascicularis</term><term>Male</term><term>Retina (pathology)</term><term>Tomography, Optical Coherence</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>MPTP Poisoning</term><term>Retina</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Disease Models, Animal</term><term>Macaca fascicularis</term><term>Male</term><term>Tomography, Optical Coherence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Optical coherence tomography (OCT) is a noninvasive procedure for analysis of retinal morphology. Significant changes in the thickness of the peripapillary retinal nerve fiber layer (RNFL) in Parkinson's disease (PD) have been reported, and the current study was performed to examine whether such changes can also be detected in an animal model of PD.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">25070726</PMID><DateCreated><Year>2014</Year><Month>10</Month><Day>06</Day></DateCreated><DateCompleted><Year>2015</Year><Month>06</Month><Day>03</Day></DateCompleted><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>29</Volume><Issue>12</Issue><PubDate><Year>2014</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Retinal pathology detected by optical coherence tomography in an animal model of Parkinson's disease.</ArticleTitle><Pagination><MedlinePgn>1547-51</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.25974</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Optical coherence tomography (OCT) is a noninvasive procedure for analysis of retinal morphology. Significant changes in the thickness of the peripapillary retinal nerve fiber layer (RNFL) in Parkinson's disease (PD) have been reported, and the current study was performed to examine whether such changes can also be detected in an animal model of PD.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Optical coherence tomography measurements of peripapillary RNFL thickness, macula volume, and foveal thickness were obtained from 10 normal and five 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated cynomolgus monkeys with stable Parkinsonian signs.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Average RNFL thickness was significantly decreased in Parkinsonian monkeys compared with controls, with statistically significant RNFL thinning found in nasal and inferior quadrants. Macula volume and foveal thickness were also significantly reduced in Parkinsonian animals compared with controls.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">As described in PD, RNFL thinning, reduced macula volume, and reduced foveal thickness also occurs in monkeys with MPTP-induced Parkinsonism. These findings pave the way for additional studies in which OCT may be used to track changes in the retina that might be present very early in the PD pathological process, perhaps preceding the onset of motor signs.</AbstractText><CopyrightInformation>© 2014 International Parkinson and Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Schneider</LastName><ForeName>Jay S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ault</LastName><ForeName>Mark E</ForeName><Initials>ME</Initials></Author><Author ValidYN="Y"><LastName>Anderson</LastName><ForeName>David W</ForeName><Initials>DW</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>07</Month><Day>28</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000818">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004195">Disease Models, Animal</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D020267">MPTP Poisoning</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008252">Macaca fascicularis</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012160">Retina</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000473">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D041623">Tomography, Optical Coherence</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">MPTP</Keyword><Keyword MajorTopicYN="N">Parkinson's disease</Keyword><Keyword MajorTopicYN="N">monkey</Keyword><Keyword MajorTopicYN="N">optical coherence tomography</Keyword><Keyword MajorTopicYN="N">retina</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>3</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>6</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="aheadofprint"><Year>2014</Year><Month>7</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>7</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>7</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>6</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25070726</ArticleId><ArticleId IdType="doi">10.1002/mds.25974</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region></list><tree><noCountry><name sortKey="Anderson, David W" sort="Anderson, David W" uniqKey="Anderson D" first="David W" last="Anderson">David W. Anderson</name><name sortKey="Ault, Mark E" sort="Ault, Mark E" uniqKey="Ault M" first="Mark E" last="Ault">Mark E. Ault</name></noCountry><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Schneider, Jay S" sort="Schneider, Jay S" uniqKey="Schneider J" first="Jay S" last="Schneider">Jay S. Schneider</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004064 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 004064 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:25070726
|texte= Retinal pathology detected by optical coherence tomography in an animal model of Parkinson's disease.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:25070726" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |