Movement Disorders (revue)

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Assessment of quality of life with the multiple system atrophy health-related quality of life scale.

Identifieur interne : 003839 ( Ncbi/Merge ); précédent : 003838; suivant : 003840

Assessment of quality of life with the multiple system atrophy health-related quality of life scale.

Auteurs : Wassilios G. Meissner [France] ; Alexandra Foubert-Samier ; Sandrine Dupouy ; Angélique Gerdelat-Mas ; Rachel Debs ; Fabienne Marquant ; Valérie Cochen De Cock ; Olivier Rascol ; François Tison ; Anne Pavy-Le Traon

Source :

RBID : pubmed:23033055

English descriptors

Abstract

Multiple system atrophy (MSA) has considerable effect on health-related quality of life (Hr-QoL). The aim of this study was to prospectively evaluate Hr-QoL by using the MSA health-related Quality of Life (MSA-QoL) scale.

DOI: 10.1002/mds.25174
PubMed: 23033055

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pubmed:23033055

Le document en format XML

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<nlm:affiliation>Centre de Référence Atrophie Multisystématisée, CHU de Bordeaux, Pessac, France. wassilios.meissner@chu-bordeaux.fr</nlm:affiliation>
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<name sortKey="Foubert Samier, Alexandra" sort="Foubert Samier, Alexandra" uniqKey="Foubert Samier A" first="Alexandra" last="Foubert-Samier">Alexandra Foubert-Samier</name>
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<name sortKey="Dupouy, Sandrine" sort="Dupouy, Sandrine" uniqKey="Dupouy S" first="Sandrine" last="Dupouy">Sandrine Dupouy</name>
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<name sortKey="Debs, Rachel" sort="Debs, Rachel" uniqKey="Debs R" first="Rachel" last="Debs">Rachel Debs</name>
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<name sortKey="Marquant, Fabienne" sort="Marquant, Fabienne" uniqKey="Marquant F" first="Fabienne" last="Marquant">Fabienne Marquant</name>
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<name sortKey="De Cock, Valerie Cochen" sort="De Cock, Valerie Cochen" uniqKey="De Cock V" first="Valérie Cochen" last="De Cock">Valérie Cochen De Cock</name>
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<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
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<name sortKey="Marquant, Fabienne" sort="Marquant, Fabienne" uniqKey="Marquant F" first="Fabienne" last="Marquant">Fabienne Marquant</name>
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<name sortKey="De Cock, Valerie Cochen" sort="De Cock, Valerie Cochen" uniqKey="De Cock V" first="Valérie Cochen" last="De Cock">Valérie Cochen De Cock</name>
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<name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name>
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<name sortKey="Tison, Francois" sort="Tison, Francois" uniqKey="Tison F" first="François" last="Tison">François Tison</name>
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<name sortKey="Pavy Le Traon, Anne" sort="Pavy Le Traon, Anne" uniqKey="Pavy Le Traon A" first="Anne" last="Pavy-Le Traon">Anne Pavy-Le Traon</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Multiple System Atrophy (diagnosis)</term>
<term>Multiple System Atrophy (psychology)</term>
<term>Quality of Life</term>
<term>Questionnaires</term>
<term>Severity of Illness Index</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Multiple System Atrophy</term>
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<term>Multiple System Atrophy</term>
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<term>Disability Evaluation</term>
<term>Disease Progression</term>
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<div type="abstract" xml:lang="en">Multiple system atrophy (MSA) has considerable effect on health-related quality of life (Hr-QoL). The aim of this study was to prospectively evaluate Hr-QoL by using the MSA health-related Quality of Life (MSA-QoL) scale.</div>
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<Month>10</Month>
<Day>19</Day>
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<Month>04</Month>
<Day>18</Day>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Multiple system atrophy (MSA) has considerable effect on health-related quality of life (Hr-QoL). The aim of this study was to prospectively evaluate Hr-QoL by using the MSA health-related Quality of Life (MSA-QoL) scale.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Evaluation of 100 patients at baseline and after a mean follow-up of 11.5 months was performed. Assessment was made of potential associations with established markers of disease progression. Calculation was performed of sample-size estimates for various effect sizes.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">MSA-QoL scale scores were less responsive to change than Unified MSA Rating Scale (UMSARS) scores. Responsiveness was largely improved and reasonable sample-size estimates were obtained when limiting the analysis to items with significant change over time.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The UMSARS remains the "gold standard" for disease-modifying/neuroprotection trials. An MSA-QoL Change Scale, based on the most responsive items, may become a valuable tool.</AbstractText>
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