Impaired finger dexterity in patients with parkinson's disease correlates with discriminative cutaneous sensory dysfunction.
Identifieur interne : 002D84 ( Ncbi/Merge ); précédent : 002D83; suivant : 002D85Impaired finger dexterity in patients with parkinson's disease correlates with discriminative cutaneous sensory dysfunction.
Auteurs : Myung Sik Lee [Corée du Sud] ; Chul Hyoung Lyoo ; Myung Jun Lee ; Jaeeun Sim ; Hanna Cho ; Yun Ho ChoiSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.
English descriptors
- KwdEn :
- Aged, Discrimination (Psychology), Female, Fingers (physiopathology), Humans, Male, Middle Aged, Parkinson Disease (complications), Parkinson Disease (physiopathology), Perceptual Disorders (complications), Perceptual Disorders (physiopathology), Psychomotor Performance (physiology), Regression Analysis, Severity of Illness Index, Touch Perception (physiology).
- MESH :
- complications : Parkinson Disease, Perceptual Disorders.
- physiology : Psychomotor Performance, Touch Perception.
- physiopathology : Fingers, Parkinson Disease, Perceptual Disorders.
- Aged, Discrimination (Psychology), Female, Humans, Male, Middle Aged, Regression Analysis, Severity of Illness Index.
Abstract
To study the influence of discriminative cutaneous sensory dysfunction on impaired finger dexterity in Parkinson's disease (PD), we evaluated 48 right-handed PD patients during a practically defined off-medication period and 24 healthy age-matched controls. With visual deprivation, a finger tapping task (FTT) was performed to assess the speed of simple repetitive finger movements and a coin rotation task (CRT) was used to assess finger dexterity. The tasks were performed with the right hand. We measured the somesthetic temporal discrimination threshold (sTDT) in the right index finger. The mean ± SD FTT score of the patient group was lower than that of the control group (24.0 ± 8.0 vs. 29.8 ± 7.8; P < 0.01). The patient group performed worse on the CRT than the control group (8.5 ± 3.5 vs. 12.6 ± 1.7; P < 0.001). The mean sTDT value of the patient group was longer than that of the control group (124.0 ± 44.8 vs. 78.1 ± 26.2 ms; P < 0.001). The CRT scores correlated with the sTDT values (Pearson's correlation coefficient = -0.43; P < 0.01), but not with the Unified Parkinson's Disease Rating Scale (UPDRS) finger bradykinesia scores or FTT scores. Multiple regression analysis showed that the sTDT values (parameter estimate = -0.03, SE = 0.01; P < 0.01), but not patient age, UPDRS finger bradykinesia score, or FTT score, affected the CRT score. Slowness of simple repetitive finger movements did not have a strong impact on the impaired manual dexterity of PD. Discriminative sensory dysfunction and consequent abnormal sensorimotor integration seem to be involved in the impaired finger dexterity of PD.
DOI: 10.1002/mds.23304
PubMed: 20721911
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001633
- to stream PubMed, to step Curation: 001633
- to stream PubMed, to step Checkpoint: 001835
Links to Exploration step
pubmed:20721911Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Impaired finger dexterity in patients with parkinson's disease correlates with discriminative cutaneous sensory dysfunction.</title><author><name sortKey="Lee, Myung Sik" sort="Lee, Myung Sik" uniqKey="Lee M" first="Myung Sik" last="Lee">Myung Sik Lee</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. mslee@yuhs.ac</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Lyoo, Chul Hyoung" sort="Lyoo, Chul Hyoung" uniqKey="Lyoo C" first="Chul Hyoung" last="Lyoo">Chul Hyoung Lyoo</name></author><author><name sortKey="Lee, Myung Jun" sort="Lee, Myung Jun" uniqKey="Lee M" first="Myung Jun" last="Lee">Myung Jun Lee</name></author><author><name sortKey="Sim, Jaeeun" sort="Sim, Jaeeun" uniqKey="Sim J" first="Jaeeun" last="Sim">Jaeeun Sim</name></author><author><name sortKey="Cho, Hanna" sort="Cho, Hanna" uniqKey="Cho H" first="Hanna" last="Cho">Hanna Cho</name></author><author><name sortKey="Choi, Yun Ho" sort="Choi, Yun Ho" uniqKey="Choi Y" first="Yun Ho" last="Choi">Yun Ho Choi</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1002/mds.23304</idno><idno type="RBID">pubmed:20721911</idno><idno type="pmid">20721911</idno><idno type="wicri:Area/PubMed/Corpus">001633</idno><idno type="wicri:Area/PubMed/Curation">001633</idno><idno type="wicri:Area/PubMed/Checkpoint">001835</idno><idno type="wicri:Area/Ncbi/Merge">002D84</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Impaired finger dexterity in patients with parkinson's disease correlates with discriminative cutaneous sensory dysfunction.</title><author><name sortKey="Lee, Myung Sik" sort="Lee, Myung Sik" uniqKey="Lee M" first="Myung Sik" last="Lee">Myung Sik Lee</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. mslee@yuhs.ac</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Lyoo, Chul Hyoung" sort="Lyoo, Chul Hyoung" uniqKey="Lyoo C" first="Chul Hyoung" last="Lyoo">Chul Hyoung Lyoo</name></author><author><name sortKey="Lee, Myung Jun" sort="Lee, Myung Jun" uniqKey="Lee M" first="Myung Jun" last="Lee">Myung Jun Lee</name></author><author><name sortKey="Sim, Jaeeun" sort="Sim, Jaeeun" uniqKey="Sim J" first="Jaeeun" last="Sim">Jaeeun Sim</name></author><author><name sortKey="Cho, Hanna" sort="Cho, Hanna" uniqKey="Cho H" first="Hanna" last="Cho">Hanna Cho</name></author><author><name sortKey="Choi, Yun Ho" sort="Choi, Yun Ho" uniqKey="Choi Y" first="Yun Ho" last="Choi">Yun Ho Choi</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Discrimination (Psychology)</term><term>Female</term><term>Fingers (physiopathology)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (physiopathology)</term><term>Perceptual Disorders (complications)</term><term>Perceptual Disorders (physiopathology)</term><term>Psychomotor Performance (physiology)</term><term>Regression Analysis</term><term>Severity of Illness Index</term><term>Touch Perception (physiology)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term><term>Perceptual Disorders</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Psychomotor Performance</term><term>Touch Perception</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Fingers</term><term>Parkinson Disease</term><term>Perceptual Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Discrimination (Psychology)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Regression Analysis</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To study the influence of discriminative cutaneous sensory dysfunction on impaired finger dexterity in Parkinson's disease (PD), we evaluated 48 right-handed PD patients during a practically defined off-medication period and 24 healthy age-matched controls. With visual deprivation, a finger tapping task (FTT) was performed to assess the speed of simple repetitive finger movements and a coin rotation task (CRT) was used to assess finger dexterity. The tasks were performed with the right hand. We measured the somesthetic temporal discrimination threshold (sTDT) in the right index finger. The mean ± SD FTT score of the patient group was lower than that of the control group (24.0 ± 8.0 vs. 29.8 ± 7.8; P < 0.01). The patient group performed worse on the CRT than the control group (8.5 ± 3.5 vs. 12.6 ± 1.7; P < 0.001). The mean sTDT value of the patient group was longer than that of the control group (124.0 ± 44.8 vs. 78.1 ± 26.2 ms; P < 0.001). The CRT scores correlated with the sTDT values (Pearson's correlation coefficient = -0.43; P < 0.01), but not with the Unified Parkinson's Disease Rating Scale (UPDRS) finger bradykinesia scores or FTT scores. Multiple regression analysis showed that the sTDT values (parameter estimate = -0.03, SE = 0.01; P < 0.01), but not patient age, UPDRS finger bradykinesia score, or FTT score, affected the CRT score. Slowness of simple repetitive finger movements did not have a strong impact on the impaired manual dexterity of PD. Discriminative sensory dysfunction and consequent abnormal sensorimotor integration seem to be involved in the impaired finger dexterity of PD.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">20721911</PMID><DateCreated><Year>2010</Year><Month>11</Month><Day>11</Day></DateCreated><DateCompleted><Year>2011</Year><Month>02</Month><Day>25</Day></DateCompleted><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>25</Volume><Issue>15</Issue><PubDate><Year>2010</Year><Month>Nov</Month><Day>15</Day></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Impaired finger dexterity in patients with parkinson's disease correlates with discriminative cutaneous sensory dysfunction.</ArticleTitle><Pagination><MedlinePgn>2531-5</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1002/mds.23304</ELocationID><Abstract><AbstractText>To study the influence of discriminative cutaneous sensory dysfunction on impaired finger dexterity in Parkinson's disease (PD), we evaluated 48 right-handed PD patients during a practically defined off-medication period and 24 healthy age-matched controls. With visual deprivation, a finger tapping task (FTT) was performed to assess the speed of simple repetitive finger movements and a coin rotation task (CRT) was used to assess finger dexterity. The tasks were performed with the right hand. We measured the somesthetic temporal discrimination threshold (sTDT) in the right index finger. The mean ± SD FTT score of the patient group was lower than that of the control group (24.0 ± 8.0 vs. 29.8 ± 7.8; P < 0.01). The patient group performed worse on the CRT than the control group (8.5 ± 3.5 vs. 12.6 ± 1.7; P < 0.001). The mean sTDT value of the patient group was longer than that of the control group (124.0 ± 44.8 vs. 78.1 ± 26.2 ms; P < 0.001). The CRT scores correlated with the sTDT values (Pearson's correlation coefficient = -0.43; P < 0.01), but not with the Unified Parkinson's Disease Rating Scale (UPDRS) finger bradykinesia scores or FTT scores. Multiple regression analysis showed that the sTDT values (parameter estimate = -0.03, SE = 0.01; P < 0.01), but not patient age, UPDRS finger bradykinesia score, or FTT score, affected the CRT score. Slowness of simple repetitive finger movements did not have a strong impact on the impaired manual dexterity of PD. Discriminative sensory dysfunction and consequent abnormal sensorimotor integration seem to be involved in the impaired finger dexterity of PD.</AbstractText><CopyrightInformation>© 2010 Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Myung Sik</ForeName><Initials>MS</Initials><AffiliationInfo><Affiliation>Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. mslee@yuhs.ac</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lyoo</LastName><ForeName>Chul Hyoung</ForeName><Initials>CH</Initials></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Myung Jun</ForeName><Initials>MJ</Initials></Author><Author ValidYN="Y"><LastName>Sim</LastName><ForeName>Jaeeun</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Cho</LastName><ForeName>Hanna</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Choi</LastName><ForeName>Yun Ho</ForeName><Initials>YH</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y" UI="D004192">Discrimination (Psychology)</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005385">Fingers</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010468">Perceptual Disorders</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000150">complications</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011597">Psychomotor Performance</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012044">Regression Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012720">Severity of Illness Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D055698">Touch Perception</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>8</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>8</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2011</Year><Month>2</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.1002/mds.23304</ArticleId><ArticleId IdType="pubmed">20721911</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Corée du Sud</li></country><settlement><li>Séoul</li></settlement></list><tree><noCountry><name sortKey="Cho, Hanna" sort="Cho, Hanna" uniqKey="Cho H" first="Hanna" last="Cho">Hanna Cho</name><name sortKey="Choi, Yun Ho" sort="Choi, Yun Ho" uniqKey="Choi Y" first="Yun Ho" last="Choi">Yun Ho Choi</name><name sortKey="Lee, Myung Jun" sort="Lee, Myung Jun" uniqKey="Lee M" first="Myung Jun" last="Lee">Myung Jun Lee</name><name sortKey="Lyoo, Chul Hyoung" sort="Lyoo, Chul Hyoung" uniqKey="Lyoo C" first="Chul Hyoung" last="Lyoo">Chul Hyoung Lyoo</name><name sortKey="Sim, Jaeeun" sort="Sim, Jaeeun" uniqKey="Sim J" first="Jaeeun" last="Sim">Jaeeun Sim</name></noCountry><country name="Corée du Sud"><noRegion><name sortKey="Lee, Myung Sik" sort="Lee, Myung Sik" uniqKey="Lee M" first="Myung Sik" last="Lee">Myung Sik Lee</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002D84 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 002D84 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:20721911
|texte= Impaired finger dexterity in patients with parkinson's disease correlates with discriminative cutaneous sensory dysfunction.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:20721911" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |