Movement Disorders (revue)

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Contrast sensitivity in Parkinson's disease patients with subthalamic nucleus deep brain stimulation.

Identifieur interne : 002553 ( Ncbi/Merge ); précédent : 002552; suivant : 002554

Contrast sensitivity in Parkinson's disease patients with subthalamic nucleus deep brain stimulation.

Auteurs : Kelvin L. Chou [États-Unis] ; Melissa M. Amick ; Margaret Gagner

Source :

RBID : pubmed:19224590

English descriptors

Abstract

This study examined whether deep brain stimulation (DBS) would affect the contrast sensitivity (CS) curve in patients with PD. CS was tested in 12 nondemented PD patients treated with bilateral subthalamic nucleus DBS on and off stimulation and medications. Neither stimulation condition (on vs. off) nor medications altered CS performance in this group of patients. However, collapsed across conditions, patients with bipolar stimulation in this study had significantly poorer CS at higher spatial frequencies (12 and 18 cycles per degree) than patients with monopolar stimulation. This suggests that CS deficits in PD may possibly be influenced by DBS polarity and merits further study.

DOI: 10.1002/mds.22243
PubMed: 19224590

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pubmed:19224590

Le document en format XML

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<div type="abstract" xml:lang="en">This study examined whether deep brain stimulation (DBS) would affect the contrast sensitivity (CS) curve in patients with PD. CS was tested in 12 nondemented PD patients treated with bilateral subthalamic nucleus DBS on and off stimulation and medications. Neither stimulation condition (on vs. off) nor medications altered CS performance in this group of patients. However, collapsed across conditions, patients with bipolar stimulation in this study had significantly poorer CS at higher spatial frequencies (12 and 18 cycles per degree) than patients with monopolar stimulation. This suggests that CS deficits in PD may possibly be influenced by DBS polarity and merits further study.</div>
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