Levodopa-related motor complications--phenomenology.
Identifieur interne : 002310 ( Ncbi/Merge ); précédent : 002309; suivant : 002311Levodopa-related motor complications--phenomenology.
Auteurs : Susan H. Fox [Canada] ; Anthony E. LangSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.
English descriptors
- KwdEn :
- Antiparkinson Agents (adverse effects), Cognition Disorders (chemically induced), Disease Progression, Drug Administration Schedule, Dyskinesias (etiology), Fatigue, Humans, Levodopa (adverse effects), Levodopa (pharmacokinetics), Levodopa (therapeutic use), Mood Disorders (chemically induced), Motor Activity (drug effects), Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson Disease (psychology), Treatment Failure.
- MESH :
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- chemically induced : Cognition Disorders, Mood Disorders.
- drug effects : Motor Activity.
- drug therapy : Parkinson Disease.
- etiology : Dyskinesias.
- chemical , pharmacokinetics : Levodopa.
- physiopathology : Parkinson Disease.
- psychology : Parkinson Disease.
- chemical , therapeutic use : Levodopa.
- Disease Progression, Drug Administration Schedule, Fatigue, Humans, Treatment Failure.
Abstract
Long term levodopa therapy in Parkinson's disease (PD) results in a range of problems. These include fluctuations in FD symptoms termed motor fluctuations, as well as non-motor symptoms, termed non-motor fluctuations. Here we review the phenomenology and methods of assessing these levodopa-related complications.
DOI: 10.1002/mds.22021
PubMed: 18781677
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pubmed:18781677Le document en format XML
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<affiliation wicri:level="4"><nlm:affiliation>Division of Neurology, Toronto Western Hospital, Movement Disorders Clinic, University of Toronto, Toronto, Ontario, Canada. sfox@uhnresearch.ca</nlm:affiliation>
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<wicri:regionArea>Division of Neurology, Toronto Western Hospital, Movement Disorders Clinic, University of Toronto, Toronto, Ontario</wicri:regionArea>
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<term>Dyskinesias (etiology)</term>
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<term>Levodopa (pharmacokinetics)</term>
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<front><div type="abstract" xml:lang="en">Long term levodopa therapy in Parkinson's disease (PD) results in a range of problems. These include fluctuations in FD symptoms termed motor fluctuations, as well as non-motor symptoms, termed non-motor fluctuations. Here we review the phenomenology and methods of assessing these levodopa-related complications.</div>
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<DateRevised><Year>2013</Year>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<CopyrightInformation>(c) 2008 Movement Disorder Society.</CopyrightInformation>
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