Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia
Identifieur interne : 002296 ( Ncbi/Merge ); précédent : 002295; suivant : 002297Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia
Auteurs : Roy C. Martin [États-Unis] ; Ozioma C. Okonkwo [États-Unis] ; Joni Hill [États-Unis] ; H. Randall Griffith [États-Unis] ; Kristen Triebel [États-Unis] ; Alfred Bartolucci [États-Unis] ; Anthony P. Nicholas [États-Unis] ; Ray L. Watts [États-Unis] ; Natividad Stover [États-Unis] ; Lindy E. Harrell [États-Unis] ; David Clark [États-Unis] ; Daniel C. Marson [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2008.
English descriptors
- KwdEn :
- Aged, Case-Control Studies, Cognition Disorders (complications), Cognition Disorders (psychology), Decision Making (physiology), Dementia (complications), Female, Humans, Informed Consent (psychology), Informed Consent (standards), Male, Mental Competency, Middle Aged, Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (psychology), Physician-Patient Relations, Retrospective Studies.
- MESH :
- complications : Cognition Disorders, Dementia, Parkinson Disease.
- physiology : Decision Making.
- psychology : Cognition Disorders, Informed Consent, Parkinson Disease.
- standards : Informed Consent.
- Aged, Case-Control Studies, Female, Humans, Male, Mental Competency, Middle Aged, Neuropsychological Tests, Physician-Patient Relations, Retrospective Studies.
Abstract
Little is currently known about the higher order functional skills of patients with Parkinson disease and cognitive impairment. Medical decision-making capacity (MDC) was assessed in patients with Parkinson's disease (PD) with cognitive impairment and dementia. Participants were 16 patients with PD and cognitive impairment without dementia (PD-CIND), 16 patients with PD dementia (PDD), and 22 healthy older adults. All participants were administered the Capacity to Consent to Treatment Instrument (CCTI), a standardized capacity instrument assessing MDC under five different consent standards. Parametric and non-parametric statistical analyses were utilized to examine capacity performance on the consent standards. In addition, capacity outcomes (capable, marginally capable, or incapable outcomes) on the standards were identified for the two patient groups. Relative to controls, PD-CIND patients demonstrated significant impairment on the understanding treatment consent standard, clinically the most stringent CCTI standard. Relative to controls and PD-CIND patients, patients with PDD patients were impaired on the three clinical standards of
Url:
DOI: 10.1002/mds.22170
PubMed: 18759361
PubMed Central: 2579319
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000034
- to stream Pmc, to step Curation: 000034
- to stream Pmc, to step Checkpoint: 000442
- to stream PubMed, to step Corpus: 002067
- to stream PubMed, to step Curation: 002067
- to stream PubMed, to step Checkpoint: 002223
Links to Exploration step
PMC:2579319Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia</title>
<author><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C." last="Martin">Roy C. Martin</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C." last="Okonkwo">Ozioma C. Okonkwo</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H. Randall" last="Griffith">H. Randall Griffith</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L." last="Watts">Ray L. Watts</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C." last="Marson">Daniel C. Marson</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">18759361</idno>
<idno type="pmc">2579319</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579319</idno>
<idno type="RBID">PMC:2579319</idno>
<idno type="doi">10.1002/mds.22170</idno>
<date when="2008">2008</date>
<idno type="wicri:Area/Pmc/Corpus">000034</idno>
<idno type="wicri:Area/Pmc/Curation">000034</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000442</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">002067</idno>
<idno type="wicri:Area/PubMed/Curation">002067</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002223</idno>
<idno type="wicri:Area/Ncbi/Merge">002296</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia</title>
<author><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C." last="Martin">Roy C. Martin</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C." last="Okonkwo">Ozioma C. Okonkwo</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H. Randall" last="Griffith">H. Randall Griffith</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L." last="Watts">Ray L. Watts</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C." last="Marson">Daniel C. Marson</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Case-Control Studies</term>
<term>Cognition Disorders (complications)</term>
<term>Cognition Disorders (psychology)</term>
<term>Decision Making (physiology)</term>
<term>Dementia (complications)</term>
<term>Female</term>
<term>Humans</term>
<term>Informed Consent (psychology)</term>
<term>Informed Consent (standards)</term>
<term>Male</term>
<term>Mental Competency</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (psychology)</term>
<term>Physician-Patient Relations</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Cognition Disorders</term>
<term>Dementia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Decision Making</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Cognition Disorders</term>
<term>Informed Consent</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Informed Consent</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Case-Control Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Mental Competency</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Physician-Patient Relations</term>
<term>Retrospective Studies</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Little is currently known about the higher order functional skills of patients with Parkinson disease and cognitive impairment. Medical decision-making capacity (MDC) was assessed in patients with Parkinson's disease (PD) with cognitive impairment and dementia. Participants were 16 patients with PD and cognitive impairment without dementia (PD-CIND), 16 patients with PD dementia (PDD), and 22 healthy older adults. All participants were administered the Capacity to Consent to Treatment Instrument (CCTI), a standardized capacity instrument assessing MDC under five different consent standards. Parametric and non-parametric statistical analyses were utilized to examine capacity performance on the consent standards. In addition, capacity outcomes (capable, marginally capable, or incapable outcomes) on the standards were identified for the two patient groups. Relative to controls, PD-CIND patients demonstrated significant impairment on the understanding treatment consent standard, clinically the most stringent CCTI standard. Relative to controls and PD-CIND patients, patients with PDD patients were impaired on the three clinical standards of <italic>understanding</italic>
, <italic>reasoning</italic>
, and <italic>appreciation</italic>
. The findings suggest that impairment in decisional capacity is already present in cognitively impaired PD patients without dementia, and increases as these patients develop dementia. Clinicians and researchers should carefully assess decisional capacity in all PD patients with cognitive impairment.</p>
</div>
</front>
</TEI>
<double pmid="18759361"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia</title>
<author><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C." last="Martin">Roy C. Martin</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C." last="Okonkwo">Ozioma C. Okonkwo</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H. Randall" last="Griffith">H. Randall Griffith</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L." last="Watts">Ray L. Watts</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C." last="Marson">Daniel C. Marson</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">18759361</idno>
<idno type="pmc">2579319</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579319</idno>
<idno type="RBID">PMC:2579319</idno>
<idno type="doi">10.1002/mds.22170</idno>
<date when="2008">2008</date>
<idno type="wicri:Area/Pmc/Corpus">000034</idno>
<idno type="wicri:Area/Pmc/Curation">000034</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000442</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia</title>
<author><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C." last="Martin">Roy C. Martin</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C." last="Okonkwo">Ozioma C. Okonkwo</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name>
<affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H. Randall" last="Griffith">H. Randall Griffith</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L." last="Watts">Ray L. Watts</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C." last="Marson">Daniel C. Marson</name>
<affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Alabama</region>
</placeName>
<wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Little is currently known about the higher order functional skills of patients with Parkinson disease and cognitive impairment. Medical decision-making capacity (MDC) was assessed in patients with Parkinson's disease (PD) with cognitive impairment and dementia. Participants were 16 patients with PD and cognitive impairment without dementia (PD-CIND), 16 patients with PD dementia (PDD), and 22 healthy older adults. All participants were administered the Capacity to Consent to Treatment Instrument (CCTI), a standardized capacity instrument assessing MDC under five different consent standards. Parametric and non-parametric statistical analyses were utilized to examine capacity performance on the consent standards. In addition, capacity outcomes (capable, marginally capable, or incapable outcomes) on the standards were identified for the two patient groups. Relative to controls, PD-CIND patients demonstrated significant impairment on the understanding treatment consent standard, clinically the most stringent CCTI standard. Relative to controls and PD-CIND patients, patients with PDD patients were impaired on the three clinical standards of <italic>understanding</italic>
, <italic>reasoning</italic>
, and <italic>appreciation</italic>
. The findings suggest that impairment in decisional capacity is already present in cognitively impaired PD patients without dementia, and increases as these patients develop dementia. Clinicians and researchers should carefully assess decisional capacity in all PD patients with cognitive impairment.</p>
</div>
</front>
</TEI>
</pmc>
<pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Medical decision-making capacity in cognitively impaired Parkinson's disease patients without dementia.</title>
<author><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C" last="Martin">Roy C. Martin</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017</wicri:regionArea>
<wicri:noRegion>Alabama 35294-0017</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C" last="Okonkwo">Ozioma C. Okonkwo</name>
</author>
<author><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name>
</author>
<author><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H Randall" last="Griffith">H Randall Griffith</name>
</author>
<author><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name>
</author>
<author><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name>
</author>
<author><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P" last="Nicholas">Anthony P. Nicholas</name>
</author>
<author><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L" last="Watts">Ray L. Watts</name>
</author>
<author><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name>
</author>
<author><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E" last="Harrell">Lindy E. Harrell</name>
</author>
<author><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name>
</author>
<author><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C" last="Marson">Daniel C. Marson</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2008">2008</date>
<idno type="doi">10.1002/mds.22170</idno>
<idno type="RBID">pubmed:18759361</idno>
<idno type="pmid">18759361</idno>
<idno type="wicri:Area/PubMed/Corpus">002067</idno>
<idno type="wicri:Area/PubMed/Curation">002067</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002223</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Medical decision-making capacity in cognitively impaired Parkinson's disease patients without dementia.</title>
<author><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C" last="Martin">Roy C. Martin</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0017</wicri:regionArea>
<wicri:noRegion>Alabama 35294-0017</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C" last="Okonkwo">Ozioma C. Okonkwo</name>
</author>
<author><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name>
</author>
<author><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H Randall" last="Griffith">H Randall Griffith</name>
</author>
<author><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name>
</author>
<author><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name>
</author>
<author><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P" last="Nicholas">Anthony P. Nicholas</name>
</author>
<author><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L" last="Watts">Ray L. Watts</name>
</author>
<author><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name>
</author>
<author><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E" last="Harrell">Lindy E. Harrell</name>
</author>
<author><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name>
</author>
<author><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C" last="Marson">Daniel C. Marson</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2008" type="published">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Case-Control Studies</term>
<term>Cognition Disorders (complications)</term>
<term>Cognition Disorders (psychology)</term>
<term>Decision Making (physiology)</term>
<term>Dementia (complications)</term>
<term>Female</term>
<term>Humans</term>
<term>Informed Consent (psychology)</term>
<term>Informed Consent (standards)</term>
<term>Male</term>
<term>Mental Competency</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (psychology)</term>
<term>Physician-Patient Relations</term>
<term>Retrospective Studies</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Cognition Disorders</term>
<term>Dementia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Decision Making</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Cognition Disorders</term>
<term>Informed Consent</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Informed Consent</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Case-Control Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Mental Competency</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Physician-Patient Relations</term>
<term>Retrospective Studies</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Little is currently known about the higher order functional skills of patients with Parkinson disease and cognitive impairment. Medical decision-making capacity (MDC) was assessed in patients with Parkinson's disease (PD) with cognitive impairment and dementia. Participants were 16 patients with PD and cognitive impairment without dementia (PD-CIND), 16 patients with PD dementia (PDD), and 22 healthy older adults. All participants were administered the Capacity to Consent to Treatment Instrument (CCTI), a standardized capacity instrument assessing MDC under five different consent standards. Parametric and nonparametric statistical analyses were utilized to examine capacity performance on the consent standards. In addition, capacity outcomes (capable, marginally capable, or incapable outcomes) on the standards were identified for the two patient groups. Relative to controls, PD-CIND patients demonstrated significant impairment on the understanding treatment consent standard, clinically the most stringent CCTI standard. Relative to controls and PD-CIND patients, PDD patients were impaired on the three clinical standards of understanding, reasoning, and appreciation. The findings suggest that impairment in decisional capacity is already present in cognitively impaired patients with PD without dementia and increases as these patients develop dementia. Clinicians and researchers should carefully assess decisional capacity in all patients with PD with cognitive impairment.</div>
</front>
</TEI>
</pubmed>
</double>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002296 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 002296 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Ncbi |étape= Merge |type= RBID |clé= PMC:2579319 |texte= Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:18759361" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \ | NlmPubMed2Wicri -a MovDisordV3
![]() | This area was generated with Dilib version V0.6.23. | ![]() |