Deep brain pulse-generator and lead-extensions: subjective sensations related to measured parameters.
Identifieur interne : 002077 ( Ncbi/Merge ); précédent : 002076; suivant : 002078Deep brain pulse-generator and lead-extensions: subjective sensations related to measured parameters.
Auteurs : Camillo Sherif [Autriche] ; Christian Dorfer ; Karin Kalteis ; Caroline Thun ; Iris Kaiser ; Daniel Gibson ; François AleschSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.
English descriptors
- KwdEn :
- MESH :
- adverse effects : Deep Brain Stimulation.
- diagnosis : Parkinson Disease.
- epidemiology : Parkinson Disease.
- instrumentation : Deep Brain Stimulation.
- Body Mass Index, Equipment Design, Humans, Questionnaires.
Abstract
This study analyzed subjective sensations caused by DBS pulse-generator and lead-extensions in relation with objectively measured parameters. In 50 patients implant-related sensations were evaluated. The pulse-generator mobility was video-analyzed. Insufficient lead-extension/pulse-generator tolerability (72%/84%) was documented. Furthermore, 54% of the patients described movement impairments and 48% cosmetic deformity. High body mass index (BMI) was associated with low lead-extension related pain (P < 0.001). High generator mobility resulted in high lead-extension related pain (P < 0.001). Compared with lead-extension type 7482, type 7495 showed less lead-extension related pain (P = 0.0138), we suppose secondary to surgical tunneling instruments with a larger tip diameter. The lead-extension path with one tissue tunnel for both lead-extensions had 36% lead-extension related pain versus 11% for the path with one single tunnel for each lead-extension. Smaller pulse-generators for better cosmetic results, surgical procedures using larger tunneling instruments and one single tunnel for each lead-extension would provide better results for patients with BMI <30.
DOI: 10.1002/mds.21973
PubMed: 18381642
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pubmed:18381642Le document en format XML
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<author><name sortKey="Sherif, Camillo" sort="Sherif, Camillo" uniqKey="Sherif C" first="Camillo" last="Sherif">Camillo Sherif</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Neurosurgery, Medical University of Vienna, Vienna, Austria. camillo.sherif@meduniwien.ac.at</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Neurosurgery, Medical University of Vienna, Vienna</wicri:regionArea>
<placeName><settlement type="city">Vienne (Autriche)</settlement>
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<author><name sortKey="Dorfer, Christian" sort="Dorfer, Christian" uniqKey="Dorfer C" first="Christian" last="Dorfer">Christian Dorfer</name>
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<author><name sortKey="Kalteis, Karin" sort="Kalteis, Karin" uniqKey="Kalteis K" first="Karin" last="Kalteis">Karin Kalteis</name>
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<author><name sortKey="Thun, Caroline" sort="Thun, Caroline" uniqKey="Thun C" first="Caroline" last="Thun">Caroline Thun</name>
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<author><name sortKey="Kaiser, Iris" sort="Kaiser, Iris" uniqKey="Kaiser I" first="Iris" last="Kaiser">Iris Kaiser</name>
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<author><name sortKey="Gibson, Daniel" sort="Gibson, Daniel" uniqKey="Gibson D" first="Daniel" last="Gibson">Daniel Gibson</name>
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<author><name sortKey="Alesch, Francois" sort="Alesch, Francois" uniqKey="Alesch F" first="François" last="Alesch">François Alesch</name>
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<term>Equipment Design</term>
<term>Humans</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (epidemiology)</term>
<term>Questionnaires</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Deep Brain Stimulation</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Parkinson Disease</term>
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<keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Deep Brain Stimulation</term>
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<front><div type="abstract" xml:lang="en">This study analyzed subjective sensations caused by DBS pulse-generator and lead-extensions in relation with objectively measured parameters. In 50 patients implant-related sensations were evaluated. The pulse-generator mobility was video-analyzed. Insufficient lead-extension/pulse-generator tolerability (72%/84%) was documented. Furthermore, 54% of the patients described movement impairments and 48% cosmetic deformity. High body mass index (BMI) was associated with low lead-extension related pain (P < 0.001). High generator mobility resulted in high lead-extension related pain (P < 0.001). Compared with lead-extension type 7482, type 7495 showed less lead-extension related pain (P = 0.0138), we suppose secondary to surgical tunneling instruments with a larger tip diameter. The lead-extension path with one tissue tunnel for both lead-extensions had 36% lead-extension related pain versus 11% for the path with one single tunnel for each lead-extension. Smaller pulse-generators for better cosmetic results, surgical procedures using larger tunneling instruments and one single tunnel for each lead-extension would provide better results for patients with BMI <30.</div>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<ArticleTitle>Deep brain pulse-generator and lead-extensions: subjective sensations related to measured parameters.</ArticleTitle>
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<Abstract><AbstractText>This study analyzed subjective sensations caused by DBS pulse-generator and lead-extensions in relation with objectively measured parameters. In 50 patients implant-related sensations were evaluated. The pulse-generator mobility was video-analyzed. Insufficient lead-extension/pulse-generator tolerability (72%/84%) was documented. Furthermore, 54% of the patients described movement impairments and 48% cosmetic deformity. High body mass index (BMI) was associated with low lead-extension related pain (P < 0.001). High generator mobility resulted in high lead-extension related pain (P < 0.001). Compared with lead-extension type 7482, type 7495 showed less lead-extension related pain (P = 0.0138), we suppose secondary to surgical tunneling instruments with a larger tip diameter. The lead-extension path with one tissue tunnel for both lead-extensions had 36% lead-extension related pain versus 11% for the path with one single tunnel for each lead-extension. Smaller pulse-generators for better cosmetic results, surgical procedures using larger tunneling instruments and one single tunnel for each lead-extension would provide better results for patients with BMI <30.</AbstractText>
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<name sortKey="Gibson, Daniel" sort="Gibson, Daniel" uniqKey="Gibson D" first="Daniel" last="Gibson">Daniel Gibson</name>
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