Executive dysfunction using behavioral assessment of the dysexecutive syndrome in Parkinson's disease.
Identifieur interne : 001F84 ( Ncbi/Merge ); précédent : 001F83; suivant : 001F85Executive dysfunction using behavioral assessment of the dysexecutive syndrome in Parkinson's disease.
Auteurs : Satoshi Kamei [Japon] ; Motohiko Hara ; Kan Serizawa ; Masato Murakami ; Tomohiko Mizutani ; Motoko Ishiburo ; Ritsuko Kawahara ; Yukiko Takagi ; Katsuhiko Ogawa ; Hirokazu Yoshihashi ; Satoru Shinbo ; Yutaka Suzuki ; Mai Yamaguchi ; Akihiko Morita ; Jun Takeshita ; Kaname HirayanagiSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Cognition Disorders (diagnosis), Cognition Disorders (etiology), Disability Evaluation, Disease Progression, Female, Humans, Male, Middle Aged, Movement Disorders (diagnosis), Movement Disorders (etiology), Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (diagnosis), Risk Factors, Severity of Illness Index.
- MESH :
- complications : Parkinson Disease.
- diagnosis : Cognition Disorders, Movement Disorders, Parkinson Disease.
- etiology : Cognition Disorders, Movement Disorders.
- Aged, Aged, 80 and over, Disability Evaluation, Disease Progression, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Risk Factors, Severity of Illness Index.
Abstract
The objective of this study was to evaluate the executive dysfunction (ExD) in Parkinson's disease (PD) using the Behavioral Assessment of the Dysexecutive Syndrome (BADS), which provides a wide-range assessment of ExD. The BADS and the Unified Parkinson's Disease Rating Scale (UPDRS) were investigated in 63 nondemented PD patients who revealed scores of >or=24 points on the Mini-Mental State Examination based on the DSM-IV. Multiple logistic regression analysis was performed to evaluate the predisposing factors to ExD, which was defined as <70 points on the age-controlled standardized score. The total score on the UPDRS was a significant independent predisposing factor to ExD. Among the various parts of the UPDRS, part II was the significant factor for ExD. The profile scores of all subtests on the BADS in patients with ExD were significantly lower than those of patients without ExD. All profile scores decreased with severity of PD, but the changes among these scores differed. ExD in nondemented PD predisposed to a greater severity of PD, particularly as regards the activity of daily living impairment. Nondemented PD revealed wide-range components of ExD. All components of ExD were impaired with severity of PD, but the patterns of each component exhibited variety.
DOI: 10.1002/mds.21890
PubMed: 18098279
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pubmed:18098279Le document en format XML
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Serizawa</name></author><author><name sortKey="Murakami, Masato" sort="Murakami, Masato" uniqKey="Murakami M" first="Masato" last="Murakami">Masato Murakami</name></author><author><name sortKey="Mizutani, Tomohiko" sort="Mizutani, Tomohiko" uniqKey="Mizutani T" first="Tomohiko" last="Mizutani">Tomohiko Mizutani</name></author><author><name sortKey="Ishiburo, Motoko" sort="Ishiburo, Motoko" uniqKey="Ishiburo M" first="Motoko" last="Ishiburo">Motoko Ishiburo</name></author><author><name sortKey="Kawahara, Ritsuko" sort="Kawahara, Ritsuko" uniqKey="Kawahara R" first="Ritsuko" last="Kawahara">Ritsuko Kawahara</name></author><author><name sortKey="Takagi, Yukiko" sort="Takagi, Yukiko" uniqKey="Takagi Y" first="Yukiko" last="Takagi">Yukiko Takagi</name></author><author><name sortKey="Ogawa, Katsuhiko" sort="Ogawa, Katsuhiko" uniqKey="Ogawa K" first="Katsuhiko" last="Ogawa">Katsuhiko Ogawa</name></author><author><name sortKey="Yoshihashi, Hirokazu" sort="Yoshihashi, Hirokazu" 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School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Hara, Motohiko" sort="Hara, Motohiko" uniqKey="Hara M" first="Motohiko" last="Hara">Motohiko Hara</name></author><author><name sortKey="Serizawa, Kan" sort="Serizawa, Kan" uniqKey="Serizawa K" first="Kan" last="Serizawa">Kan Serizawa</name></author><author><name sortKey="Murakami, Masato" sort="Murakami, Masato" uniqKey="Murakami M" first="Masato" last="Murakami">Masato Murakami</name></author><author><name sortKey="Mizutani, Tomohiko" sort="Mizutani, Tomohiko" uniqKey="Mizutani T" first="Tomohiko" last="Mizutani">Tomohiko Mizutani</name></author><author><name sortKey="Ishiburo, Motoko" sort="Ishiburo, Motoko" uniqKey="Ishiburo M" first="Motoko" last="Ishiburo">Motoko Ishiburo</name></author><author><name sortKey="Kawahara, Ritsuko" sort="Kawahara, Ritsuko" uniqKey="Kawahara R" first="Ritsuko" last="Kawahara">Ritsuko Kawahara</name></author><author><name sortKey="Takagi, Yukiko" sort="Takagi, Yukiko" uniqKey="Takagi Y" first="Yukiko" last="Takagi">Yukiko Takagi</name></author><author><name sortKey="Ogawa, Katsuhiko" sort="Ogawa, Katsuhiko" uniqKey="Ogawa K" first="Katsuhiko" last="Ogawa">Katsuhiko Ogawa</name></author><author><name sortKey="Yoshihashi, Hirokazu" sort="Yoshihashi, Hirokazu" uniqKey="Yoshihashi H" first="Hirokazu" last="Yoshihashi">Hirokazu Yoshihashi</name></author><author><name sortKey="Shinbo, Satoru" sort="Shinbo, Satoru" uniqKey="Shinbo S" first="Satoru" last="Shinbo">Satoru Shinbo</name></author><author><name sortKey="Suzuki, Yutaka" sort="Suzuki, Yutaka" uniqKey="Suzuki Y" first="Yutaka" last="Suzuki">Yutaka Suzuki</name></author><author><name sortKey="Yamaguchi, Mai" sort="Yamaguchi, Mai" uniqKey="Yamaguchi M" first="Mai" last="Yamaguchi">Mai Yamaguchi</name></author><author><name sortKey="Morita, Akihiko" sort="Morita, Akihiko" uniqKey="Morita A" first="Akihiko" last="Morita">Akihiko Morita</name></author><author><name sortKey="Takeshita, Jun" sort="Takeshita, Jun" uniqKey="Takeshita J" first="Jun" last="Takeshita">Jun Takeshita</name></author><author><name sortKey="Hirayanagi, Kaname" sort="Hirayanagi, Kaname" uniqKey="Hirayanagi K" first="Kaname" last="Hirayanagi">Kaname Hirayanagi</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2008" type="published">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Cognition Disorders (diagnosis)</term><term>Cognition Disorders (etiology)</term><term>Disability Evaluation</term><term>Disease Progression</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Movement Disorders (diagnosis)</term><term>Movement Disorders (etiology)</term><term>Neuropsychological Tests</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (diagnosis)</term><term>Risk Factors</term><term>Severity of Illness Index</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term><term>Movement Disorders</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term><term>Movement Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Disability Evaluation</term><term>Disease Progression</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Risk Factors</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The objective of this study was to evaluate the executive dysfunction (ExD) in Parkinson's disease (PD) using the Behavioral Assessment of the Dysexecutive Syndrome (BADS), which provides a wide-range assessment of ExD. The BADS and the Unified Parkinson's Disease Rating Scale (UPDRS) were investigated in 63 nondemented PD patients who revealed scores of >or=24 points on the Mini-Mental State Examination based on the DSM-IV. Multiple logistic regression analysis was performed to evaluate the predisposing factors to ExD, which was defined as <70 points on the age-controlled standardized score. The total score on the UPDRS was a significant independent predisposing factor to ExD. Among the various parts of the UPDRS, part II was the significant factor for ExD. The profile scores of all subtests on the BADS in patients with ExD were significantly lower than those of patients without ExD. All profile scores decreased with severity of PD, but the changes among these scores differed. ExD in nondemented PD predisposed to a greater severity of PD, particularly as regards the activity of daily living impairment. Nondemented PD revealed wide-range components of ExD. All components of ExD were impaired with severity of PD, but the patterns of each component exhibited variety.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">18098279</PMID><DateCreated><Year>2008</Year><Month>04</Month><Day>03</Day></DateCreated><DateCompleted><Year>2008</Year><Month>07</Month><Day>22</Day></DateCompleted><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1531-8257</ISSN><JournalIssue CitedMedium="Internet"><Volume>23</Volume><Issue>4</Issue><PubDate><Year>2008</Year><Month>Mar</Month><Day>15</Day></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Executive dysfunction using behavioral assessment of the dysexecutive syndrome in Parkinson's disease.</ArticleTitle><Pagination><MedlinePgn>566-73</MedlinePgn></Pagination><Abstract><AbstractText>The objective of this study was to evaluate the executive dysfunction (ExD) in Parkinson's disease (PD) using the Behavioral Assessment of the Dysexecutive Syndrome (BADS), which provides a wide-range assessment of ExD. The BADS and the Unified Parkinson's Disease Rating Scale (UPDRS) were investigated in 63 nondemented PD patients who revealed scores of >or=24 points on the Mini-Mental State Examination based on the DSM-IV. Multiple logistic regression analysis was performed to evaluate the predisposing factors to ExD, which was defined as <70 points on the age-controlled standardized score. The total score on the UPDRS was a significant independent predisposing factor to ExD. Among the various parts of the UPDRS, part II was the significant factor for ExD. The profile scores of all subtests on the BADS in patients with ExD were significantly lower than those of patients without ExD. All profile scores decreased with severity of PD, but the changes among these scores differed. ExD in nondemented PD predisposed to a greater severity of PD, particularly as regards the activity of daily living impairment. Nondemented PD revealed wide-range components of ExD. All components of ExD were impaired with severity of PD, but the patterns of each component exhibited variety.</AbstractText><CopyrightInformation>(c) 2007 Movement Disorder Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kamei</LastName><ForeName>Satoshi</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Division of Neurology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan. skamei@med.nihon-u.ac.jp</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hara</LastName><ForeName>Motohiko</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Serizawa</LastName><ForeName>Kan</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Murakami</LastName><ForeName>Masato</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Mizutani</LastName><ForeName>Tomohiko</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Ishiburo</LastName><ForeName>Motoko</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Kawahara</LastName><ForeName>Ritsuko</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Takagi</LastName><ForeName>Yukiko</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Ogawa</LastName><ForeName>Katsuhiko</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Yoshihashi</LastName><ForeName>Hirokazu</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Shinbo</LastName><ForeName>Satoru</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Suzuki</LastName><ForeName>Yutaka</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Yamaguchi</LastName><ForeName>Mai</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Morita</LastName><ForeName>Akihiko</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Takeshita</LastName><ForeName>Jun</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Hirayanagi</LastName><ForeName>Kaname</ForeName><Initials>K</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000369">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D003072">Cognition Disorders</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000209">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004185">Disability Evaluation</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D018450">Disease Progression</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009069">Movement Disorders</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName><QualifierName MajorTopicYN="N" UI="Q000209">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009483">Neuropsychological Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000150">complications</QualifierName><QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012307">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012720">Severity of Illness Index</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2007</Year><Month>12</Month><Day>22</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2008</Year><Month>7</Month><Day>23</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2007</Year><Month>12</Month><Day>22</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="doi">10.1002/mds.21890</ArticleId><ArticleId IdType="pubmed">18098279</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Japon</li></country><settlement><li>Tokyo</li></settlement></list><tree><noCountry><name sortKey="Hara, Motohiko" sort="Hara, Motohiko" uniqKey="Hara M" first="Motohiko" last="Hara">Motohiko Hara</name><name sortKey="Hirayanagi, Kaname" sort="Hirayanagi, Kaname" uniqKey="Hirayanagi K" first="Kaname" last="Hirayanagi">Kaname Hirayanagi</name><name sortKey="Ishiburo, Motoko" sort="Ishiburo, Motoko" uniqKey="Ishiburo M" first="Motoko" last="Ishiburo">Motoko Ishiburo</name><name sortKey="Kawahara, Ritsuko" sort="Kawahara, Ritsuko" uniqKey="Kawahara R" first="Ritsuko" last="Kawahara">Ritsuko Kawahara</name><name sortKey="Mizutani, Tomohiko" sort="Mizutani, Tomohiko" uniqKey="Mizutani T" first="Tomohiko" last="Mizutani">Tomohiko Mizutani</name><name sortKey="Morita, Akihiko" sort="Morita, Akihiko" uniqKey="Morita A" first="Akihiko" last="Morita">Akihiko Morita</name><name sortKey="Murakami, Masato" sort="Murakami, Masato" uniqKey="Murakami M" first="Masato" last="Murakami">Masato Murakami</name><name sortKey="Ogawa, Katsuhiko" sort="Ogawa, Katsuhiko" uniqKey="Ogawa K" first="Katsuhiko" last="Ogawa">Katsuhiko Ogawa</name><name sortKey="Serizawa, Kan" sort="Serizawa, Kan" uniqKey="Serizawa K" first="Kan" last="Serizawa">Kan Serizawa</name><name sortKey="Shinbo, Satoru" sort="Shinbo, Satoru" uniqKey="Shinbo S" first="Satoru" last="Shinbo">Satoru Shinbo</name><name sortKey="Suzuki, Yutaka" sort="Suzuki, Yutaka" uniqKey="Suzuki Y" first="Yutaka" last="Suzuki">Yutaka Suzuki</name><name sortKey="Takagi, Yukiko" sort="Takagi, Yukiko" uniqKey="Takagi Y" first="Yukiko" last="Takagi">Yukiko Takagi</name><name sortKey="Takeshita, Jun" sort="Takeshita, Jun" uniqKey="Takeshita J" first="Jun" last="Takeshita">Jun Takeshita</name><name sortKey="Yamaguchi, Mai" sort="Yamaguchi, Mai" uniqKey="Yamaguchi M" first="Mai" last="Yamaguchi">Mai Yamaguchi</name><name sortKey="Yoshihashi, Hirokazu" sort="Yoshihashi, Hirokazu" uniqKey="Yoshihashi H" first="Hirokazu" last="Yoshihashi">Hirokazu Yoshihashi</name></noCountry><country name="Japon"><noRegion><name sortKey="Kamei, Satoshi" sort="Kamei, Satoshi" uniqKey="Kamei S" first="Satoshi" last="Kamei">Satoshi Kamei</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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