MovDisordV3, Ncbi, Merge, bibRecord, 001945

Pregabalin (Lyrica) in the treatment of essential tremor.

Identifieur interne : 001945 ( Ncbi/Merge ); précédent : 001944; suivant : 001946

Pregabalin (Lyrica) in the treatment of essential tremor.

Auteurs : Theresa A. Zesiewicz [États-Unis] ; Christopher L. Ward ; Robert A. Hauser ; Jessica A. Pease Campbell ; Kelly L. Sullivan

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2007.

RBID : pubmed:17089400

English descriptors

KwdEn :
- Aged, Anticonvulsants (therapeutic use), Dose-Response Relationship, Drug, Essential Tremor (drug therapy), Essential Tremor (physiopathology), Humans, Male, Middle Aged, Psychomotor Performance (drug effects), gamma-Aminobutyric Acid (analogs & derivatives), gamma-Aminobutyric Acid (therapeutic use).
MESH :
- chemical , analogs & derivatives : gamma-Aminobutyric Acid.
- chemical , therapeutic use : Anticonvulsants, gamma-Aminobutyric Acid.
- drug effects : Psychomotor Performance.
- drug therapy : Essential Tremor.
- physiopathology : Essential Tremor.
- Aged, Dose-Response Relationship, Drug, Humans, Male, Middle Aged.

Abstract

We report on 2 essential tremor patients who experienced marked improvement in upper extremity tremor with the use of pregabalin (Lyrica, PGB). On PGB 200 mg/day, tremor amplitude was reduced by at least 40% in the worst affected hand in both patients as measured by accelerometry. Both patients also reported moderate reduction in tremor on the Clinical Global Impression Scale, and Fahn-Tolosa-Marin Part I scores were markedly improved.

DOI: 10.1002/mds.21211
PubMed: 17089400

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pubmed:17089400

Le document en format XML

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<author><name sortKey="Zesiewicz, Theresa A" sort="Zesiewicz, Theresa A" uniqKey="Zesiewicz T" first="Theresa A" last="Zesiewicz">Theresa A. Zesiewicz</name>
<affiliation wicri:level="4"><nlm:affiliation>Parkinson's Disease and Movement Disorders Center, Department of Neurology, Neuroscience Program, University of South Florida, Tampa, Florida 33612, USA. tzesiewi@hsc.usf.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Parkinson's Disease and Movement Disorders Center, Department of Neurology, Neuroscience Program, University of South Florida, Tampa, Florida 33612</wicri:regionArea>
<orgName type="university">Université de Floride du Sud</orgName>
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<region type="state">Floride</region>
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<author><name sortKey="Ward, Christopher L" sort="Ward, Christopher L" uniqKey="Ward C" first="Christopher L" last="Ward">Christopher L. Ward</name>
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<author><name sortKey="Hauser, Robert A" sort="Hauser, Robert A" uniqKey="Hauser R" first="Robert A" last="Hauser">Robert A. Hauser</name>
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<author><name sortKey="Pease Campbell, Jessica A" sort="Pease Campbell, Jessica A" uniqKey="Pease Campbell J" first="Jessica A" last="Pease Campbell">Jessica A. Pease Campbell</name>
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<author><name sortKey="Sullivan, Kelly L" sort="Sullivan, Kelly L" uniqKey="Sullivan K" first="Kelly L" last="Sullivan">Kelly L. Sullivan</name>
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<author><name sortKey="Ward, Christopher L" sort="Ward, Christopher L" uniqKey="Ward C" first="Christopher L" last="Ward">Christopher L. Ward</name>
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<author><name sortKey="Hauser, Robert A" sort="Hauser, Robert A" uniqKey="Hauser R" first="Robert A" last="Hauser">Robert A. Hauser</name>
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<author><name sortKey="Pease Campbell, Jessica A" sort="Pease Campbell, Jessica A" uniqKey="Pease Campbell J" first="Jessica A" last="Pease Campbell">Jessica A. Pease Campbell</name>
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<term>Essential Tremor (physiopathology)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Psychomotor Performance (drug effects)</term>
<term>gamma-Aminobutyric Acid (analogs & derivatives)</term>
<term>gamma-Aminobutyric Acid (therapeutic use)</term>
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<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>gamma-Aminobutyric Acid</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Essential Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Essential Tremor</term>
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<front><div type="abstract" xml:lang="en">We report on 2 essential tremor patients who experienced marked improvement in upper extremity tremor with the use of pregabalin (Lyrica, PGB). On PGB 200 mg/day, tremor amplitude was reduced by at least 40% in the worst affected hand in both patients as measured by accelerometry. Both patients also reported moderate reduction in tremor on the Clinical Global Impression Scale, and Fahn-Tolosa-Marin Part I scores were markedly improved.</div>
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<DateCompleted><Year>2007</Year>
<Month>04</Month>
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<DateRevised><Year>2013</Year>
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<JournalIssue CitedMedium="Print"><Volume>22</Volume>
<Issue>1</Issue>
<PubDate><Year>2007</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
<ISOAbbreviation>Mov. Disord.</ISOAbbreviation>
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<ArticleTitle>Pregabalin (Lyrica) in the treatment of essential tremor.</ArticleTitle>
<Pagination><MedlinePgn>139-41</MedlinePgn>
</Pagination>
<Abstract><AbstractText>We report on 2 essential tremor patients who experienced marked improvement in upper extremity tremor with the use of pregabalin (Lyrica, PGB). On PGB 200 mg/day, tremor amplitude was reduced by at least 40% in the worst affected hand in both patients as measured by accelerometry. Both patients also reported moderate reduction in tremor on the Clinical Global Impression Scale, and Fahn-Tolosa-Marin Part I scores were markedly improved.</AbstractText>
<CopyrightInformation>Copyright 2006 Movement Disorder Society.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zesiewicz</LastName>
<ForeName>Theresa A</ForeName>
<Initials>TA</Initials>
<AffiliationInfo><Affiliation>Parkinson's Disease and Movement Disorders Center, Department of Neurology, Neuroscience Program, University of South Florida, Tampa, Florida 33612, USA. tzesiewi@hsc.usf.edu</Affiliation>
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<Author ValidYN="Y"><LastName>Pease Campbell</LastName>
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<tree><noCountry><name sortKey="Hauser, Robert A" sort="Hauser, Robert A" uniqKey="Hauser R" first="Robert A" last="Hauser">Robert A. Hauser</name>
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<name sortKey="Sullivan, Kelly L" sort="Sullivan, Kelly L" uniqKey="Sullivan K" first="Kelly L" last="Sullivan">Kelly L. Sullivan</name>
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<country name="États-Unis"><region name="Floride"><name sortKey="Zesiewicz, Theresa A" sort="Zesiewicz, Theresa A" uniqKey="Zesiewicz T" first="Theresa A" last="Zesiewicz">Theresa A. Zesiewicz</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Pregabalin (Lyrica) in the treatment of essential tremor.

Pregabalin (Lyrica) in the treatment of essential tremor.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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Pour générer des pages wiki