Impairment of high-contrast visual acuity in Parkinson's disease.
Identifieur interne : 001458 ( Ncbi/Merge ); précédent : 001457; suivant : 001459Impairment of high-contrast visual acuity in Parkinson's disease.
Auteurs : R D Jones [Nouvelle-Zélande] ; I M Donaldson ; P L TimmingsSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1992.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Parkinson Disease.
- physiology : Attention, Discrimination Learning, Sensory Thresholds, Visual Acuity.
- physiopathology : Parkinson Disease, Visual Cortex.
- Adult, Aged, Female, Humans, Male, Middle Aged, Vision Tests.
Abstract
Several studies have shown that the visual system is affected in Parkinson's disease (PD) with reduced contrast sensitivity, low-contrast acuity, and flicker sensitivity, as well as altered electroretinograms (ERGs) and pattern visual evoked potentials (VEPs). Apparently, however, no study has yet specifically determined whether visual acuity to high-contrast stimuli is impaired in PD. Visual acuity was measured in a group of 16 patients with PD, both on and off drugs (for 24 h), and 16 age- and sex-matched normal control subjects. Acuity was impaired in the PD group both on standard Snellen chart and on a screen in a computerized test of visual resolution. The degree of impairment was 24 and 25%, respectively, in the two tests. The PD patients had marginally better acuity on both tests while receiving drugs, but the differences were not significant. The difference between the two groups was consistent with impaired resolution and could not be accounted for by any perceptual dysfunction that may also have been present in the PD group. Conversely, however, impaired acuity may be implicated in studies that have reported mild deficits of visuospatial/visuoperceptual function in PD. Reduced acuity appears to be a subtle sequela of dopaminergic deficiency in the visual system.
DOI: 10.1002/mds.870070308
PubMed: 1620141
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 004D32
- to stream PubMed, to step Curation: 004D32
- to stream PubMed, to step Checkpoint: 004D42
Links to Exploration step
pubmed:1620141Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Impairment of high-contrast visual acuity in Parkinson's disease.</title><author><name sortKey="Jones, R D" sort="Jones, R D" uniqKey="Jones R" first="R D" last="Jones">R D Jones</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Physics and Bioengineering, Christchurch Hospital, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Department of Medical Physics and Bioengineering, Christchurch Hospital</wicri:regionArea><wicri:noRegion>Christchurch Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Donaldson, I M" sort="Donaldson, I M" uniqKey="Donaldson I" first="I M" last="Donaldson">I M Donaldson</name></author><author><name sortKey="Timmings, P L" sort="Timmings, P L" uniqKey="Timmings P" first="P L" last="Timmings">P L Timmings</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1992">1992</date><idno type="RBID">pubmed:1620141</idno><idno type="pmid">1620141</idno><idno type="doi">10.1002/mds.870070308</idno><idno type="wicri:Area/PubMed/Corpus">004D32</idno><idno type="wicri:Area/PubMed/Curation">004D32</idno><idno type="wicri:Area/PubMed/Checkpoint">004D42</idno><idno type="wicri:Area/Ncbi/Merge">001458</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Impairment of high-contrast visual acuity in Parkinson's disease.</title><author><name sortKey="Jones, R D" sort="Jones, R D" uniqKey="Jones R" first="R D" last="Jones">R D Jones</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Physics and Bioengineering, Christchurch Hospital, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Department of Medical Physics and Bioengineering, Christchurch Hospital</wicri:regionArea><wicri:noRegion>Christchurch Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Donaldson, I M" sort="Donaldson, I M" uniqKey="Donaldson I" first="I M" last="Donaldson">I M Donaldson</name></author><author><name sortKey="Timmings, P L" sort="Timmings, P L" uniqKey="Timmings P" first="P L" last="Timmings">P L Timmings</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="1992" type="published">1992</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Attention (physiology)</term><term>Discrimination Learning (physiology)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (physiopathology)</term><term>Sensory Thresholds (physiology)</term><term>Vision Tests</term><term>Visual Acuity (physiology)</term><term>Visual Cortex (physiopathology)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Attention</term><term>Discrimination Learning</term><term>Sensory Thresholds</term><term>Visual Acuity</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term><term>Visual Cortex</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Vision Tests</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Several studies have shown that the visual system is affected in Parkinson's disease (PD) with reduced contrast sensitivity, low-contrast acuity, and flicker sensitivity, as well as altered electroretinograms (ERGs) and pattern visual evoked potentials (VEPs). Apparently, however, no study has yet specifically determined whether visual acuity to high-contrast stimuli is impaired in PD. Visual acuity was measured in a group of 16 patients with PD, both on and off drugs (for 24 h), and 16 age- and sex-matched normal control subjects. Acuity was impaired in the PD group both on standard Snellen chart and on a screen in a computerized test of visual resolution. The degree of impairment was 24 and 25%, respectively, in the two tests. The PD patients had marginally better acuity on both tests while receiving drugs, but the differences were not significant. The difference between the two groups was consistent with impaired resolution and could not be accounted for by any perceptual dysfunction that may also have been present in the PD group. Conversely, however, impaired acuity may be implicated in studies that have reported mild deficits of visuospatial/visuoperceptual function in PD. Reduced acuity appears to be a subtle sequela of dopaminergic deficiency in the visual system.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">1620141</PMID><DateCreated><Year>1992</Year><Month>08</Month><Day>04</Day></DateCreated><DateCompleted><Year>1992</Year><Month>08</Month><Day>04</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN><JournalIssue CitedMedium="Print"><Volume>7</Volume><Issue>3</Issue><PubDate><Year>1992</Year></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Impairment of high-contrast visual acuity in Parkinson's disease.</ArticleTitle><Pagination><MedlinePgn>232-8</MedlinePgn></Pagination><Abstract><AbstractText>Several studies have shown that the visual system is affected in Parkinson's disease (PD) with reduced contrast sensitivity, low-contrast acuity, and flicker sensitivity, as well as altered electroretinograms (ERGs) and pattern visual evoked potentials (VEPs). Apparently, however, no study has yet specifically determined whether visual acuity to high-contrast stimuli is impaired in PD. Visual acuity was measured in a group of 16 patients with PD, both on and off drugs (for 24 h), and 16 age- and sex-matched normal control subjects. Acuity was impaired in the PD group both on standard Snellen chart and on a screen in a computerized test of visual resolution. The degree of impairment was 24 and 25%, respectively, in the two tests. The PD patients had marginally better acuity on both tests while receiving drugs, but the differences were not significant. The difference between the two groups was consistent with impaired resolution and could not be accounted for by any perceptual dysfunction that may also have been present in the PD group. Conversely, however, impaired acuity may be implicated in studies that have reported mild deficits of visuospatial/visuoperceptual function in PD. Reduced acuity appears to be a subtle sequela of dopaminergic deficiency in the visual system.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Jones</LastName><ForeName>R D</ForeName><Initials>RD</Initials><AffiliationInfo><Affiliation>Department of Medical Physics and Bioengineering, Christchurch Hospital, New Zealand.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Donaldson</LastName><ForeName>I M</ForeName><Initials>IM</Initials></Author><Author ValidYN="Y"><LastName>Timmings</LastName><ForeName>P L</ForeName><Initials>PL</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>UNITED STATES</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000328">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D001288">Attention</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D004193">Discrimination Learning</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName><QualifierName MajorTopicYN="Y" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012684">Sensory Thresholds</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014787">Vision Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014792">Visual Acuity</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D014793">Visual Cortex</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1992</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1992</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1992</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">1620141</ArticleId><ArticleId IdType="doi">10.1002/mds.870070308</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Nouvelle-Zélande</li></country></list><tree><noCountry><name sortKey="Donaldson, I M" sort="Donaldson, I M" uniqKey="Donaldson I" first="I M" last="Donaldson">I M Donaldson</name><name sortKey="Timmings, P L" sort="Timmings, P L" uniqKey="Timmings P" first="P L" last="Timmings">P L Timmings</name></noCountry><country name="Nouvelle-Zélande"><noRegion><name sortKey="Jones, R D" sort="Jones, R D" uniqKey="Jones R" first="R D" last="Jones">R D Jones</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001458 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 001458 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:1620141
|texte= Impairment of high-contrast visual acuity in Parkinson's disease.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:1620141" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |