Switching of movement direction is central to parkinsonian bradykinesia in sit-to-stand.
Identifieur interne : 000928 ( Ncbi/Merge ); précédent : 000927; suivant : 000929Switching of movement direction is central to parkinsonian bradykinesia in sit-to-stand.
Auteurs : Margaret K Y. Mak [République populaire de Chine] ; Christina W Y. Hui-ChanSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2002.
English descriptors
- KwdEn :
- Aged, Biomechanical Phenomena, Female, Humans, Hypokinesia (diagnosis), Hypokinesia (physiopathology), Male, Middle Aged, Neurologic Examination, Orientation (physiology), Parkinson Disease (diagnosis), Parkinson Disease (physiopathology), Posture (physiology), Reaction Time (physiology), Reference Values, Weight-Bearing (physiology).
- MESH :
- diagnosis : Hypokinesia, Parkinson Disease.
- physiology : Orientation, Posture, Reaction Time, Weight-Bearing.
- physiopathology : Hypokinesia, Parkinson Disease.
- Aged, Biomechanical Phenomena, Female, Humans, Male, Middle Aged, Neurologic Examination, Reference Values.
Abstract
Patients with Parkinson's disease (PD) are known to manifest slowness in movements. We sought to identify the particular kinematic and kinetic disorders that contribute to the slowness in performing sit-to-stand in these patients. Two inter-related studies were carried out. In the first study, 20 patients with PD and 20 control subjects were instructed to perform sit-to-stand at a natural speed. In the second study, 15 control subjects were instructed to simulate the slower speed of sit-to-stand of the patients identified in the first study. Kinematic and kinetic data were recorded by a PEAK motion analysis system and two force platforms. The results showed that patients with PD generated smaller peak horizontal and vertical velocities during the task. They took a longer time to complete each individual phase as well as the whole movement of sit-to-stand. Patients also produced smaller peak hip flexion and ankle dorsiflexion joint torques and had prolonged time-to-peak torques from sit-to-stand onset. When control subjects simulated the patients' speed of sit-to-stand, there was no difference in all the kinematic and kinetic data between groups. The only exception was that they exhibited a shorter transition time between peak horizontal velocity (flexion phase) and seat-off (extension phase) than the patients. This study demonstrated that the slowness of PD patients during sit-to-stand at a natural speed could be attributed to inadequate peak hip flexion and ankle dorsiflexion torques, a prolonged torque production, as well as a difficulty in switching from the flexion to extension direction during sit-to-stand. As the latter difficulty persisted when the control subjects performed the task at a speed similar to that of the patients, our findings suggest that a fundamental problem of patients with Parkinson's disease could be a switch between movement directions.
DOI: 10.1002/mds.10257
PubMed: 12465056
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 003923
- to stream PubMed, to step Curation: 003923
- to stream PubMed, to step Checkpoint: 003916
Links to Exploration step
pubmed:12465056Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Switching of movement direction is central to parkinsonian bradykinesia in sit-to-stand.</title><author><name sortKey="Mak, Margaret K Y" sort="Mak, Margaret K Y" uniqKey="Mak M" first="Margaret K Y" last="Mak">Margaret K Y. Mak</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, Republic of China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Hui Chan, Christina W Y" sort="Hui Chan, Christina W Y" uniqKey="Hui Chan C" first="Christina W Y" last="Hui-Chan">Christina W Y. Hui-Chan</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2002">2002</date><idno type="RBID">pubmed:12465056</idno><idno type="pmid">12465056</idno><idno type="doi">10.1002/mds.10257</idno><idno type="wicri:Area/PubMed/Corpus">003923</idno><idno type="wicri:Area/PubMed/Curation">003923</idno><idno type="wicri:Area/PubMed/Checkpoint">003916</idno><idno type="wicri:Area/Ncbi/Merge">000928</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Switching of movement direction is central to parkinsonian bradykinesia in sit-to-stand.</title><author><name sortKey="Mak, Margaret K Y" sort="Mak, Margaret K Y" uniqKey="Mak M" first="Margaret K Y" last="Mak">Margaret K Y. Mak</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, Republic of China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Hui Chan, Christina W Y" sort="Hui Chan, Christina W Y" uniqKey="Hui Chan C" first="Christina W Y" last="Hui-Chan">Christina W Y. Hui-Chan</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2002" type="published">2002</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Biomechanical Phenomena</term><term>Female</term><term>Humans</term><term>Hypokinesia (diagnosis)</term><term>Hypokinesia (physiopathology)</term><term>Male</term><term>Middle Aged</term><term>Neurologic Examination</term><term>Orientation (physiology)</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (physiopathology)</term><term>Posture (physiology)</term><term>Reaction Time (physiology)</term><term>Reference Values</term><term>Weight-Bearing (physiology)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hypokinesia</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Orientation</term><term>Posture</term><term>Reaction Time</term><term>Weight-Bearing</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Hypokinesia</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Biomechanical Phenomena</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neurologic Examination</term><term>Reference Values</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Patients with Parkinson's disease (PD) are known to manifest slowness in movements. We sought to identify the particular kinematic and kinetic disorders that contribute to the slowness in performing sit-to-stand in these patients. Two inter-related studies were carried out. In the first study, 20 patients with PD and 20 control subjects were instructed to perform sit-to-stand at a natural speed. In the second study, 15 control subjects were instructed to simulate the slower speed of sit-to-stand of the patients identified in the first study. Kinematic and kinetic data were recorded by a PEAK motion analysis system and two force platforms. The results showed that patients with PD generated smaller peak horizontal and vertical velocities during the task. They took a longer time to complete each individual phase as well as the whole movement of sit-to-stand. Patients also produced smaller peak hip flexion and ankle dorsiflexion joint torques and had prolonged time-to-peak torques from sit-to-stand onset. When control subjects simulated the patients' speed of sit-to-stand, there was no difference in all the kinematic and kinetic data between groups. The only exception was that they exhibited a shorter transition time between peak horizontal velocity (flexion phase) and seat-off (extension phase) than the patients. This study demonstrated that the slowness of PD patients during sit-to-stand at a natural speed could be attributed to inadequate peak hip flexion and ankle dorsiflexion torques, a prolonged torque production, as well as a difficulty in switching from the flexion to extension direction during sit-to-stand. As the latter difficulty persisted when the control subjects performed the task at a speed similar to that of the patients, our findings suggest that a fundamental problem of patients with Parkinson's disease could be a switch between movement directions.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">12465056</PMID><DateCreated><Year>2002</Year><Month>12</Month><Day>04</Day></DateCreated><DateCompleted><Year>2003</Year><Month>03</Month><Day>24</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0885-3185</ISSN><JournalIssue CitedMedium="Print"><Volume>17</Volume><Issue>6</Issue><PubDate><Year>2002</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Movement disorders : official journal of the Movement Disorder Society</Title><ISOAbbreviation>Mov. Disord.</ISOAbbreviation></Journal><ArticleTitle>Switching of movement direction is central to parkinsonian bradykinesia in sit-to-stand.</ArticleTitle><Pagination><MedlinePgn>1188-95</MedlinePgn></Pagination><Abstract><AbstractText>Patients with Parkinson's disease (PD) are known to manifest slowness in movements. We sought to identify the particular kinematic and kinetic disorders that contribute to the slowness in performing sit-to-stand in these patients. Two inter-related studies were carried out. In the first study, 20 patients with PD and 20 control subjects were instructed to perform sit-to-stand at a natural speed. In the second study, 15 control subjects were instructed to simulate the slower speed of sit-to-stand of the patients identified in the first study. Kinematic and kinetic data were recorded by a PEAK motion analysis system and two force platforms. The results showed that patients with PD generated smaller peak horizontal and vertical velocities during the task. They took a longer time to complete each individual phase as well as the whole movement of sit-to-stand. Patients also produced smaller peak hip flexion and ankle dorsiflexion joint torques and had prolonged time-to-peak torques from sit-to-stand onset. When control subjects simulated the patients' speed of sit-to-stand, there was no difference in all the kinematic and kinetic data between groups. The only exception was that they exhibited a shorter transition time between peak horizontal velocity (flexion phase) and seat-off (extension phase) than the patients. This study demonstrated that the slowness of PD patients during sit-to-stand at a natural speed could be attributed to inadequate peak hip flexion and ankle dorsiflexion torques, a prolonged torque production, as well as a difficulty in switching from the flexion to extension direction during sit-to-stand. As the latter difficulty persisted when the control subjects performed the task at a speed similar to that of the patients, our findings suggest that a fundamental problem of patients with Parkinson's disease could be a switch between movement directions.</AbstractText><CopyrightInformation>Copyright 2002 Movement Disorder Society</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mak</LastName><ForeName>Margaret K Y</ForeName><Initials>MK</Initials><AffiliationInfo><Affiliation>Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, Republic of China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hui-Chan</LastName><ForeName>Christina W Y</ForeName><Initials>CW</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mov Disord</MedlineTA><NlmUniqueID>8610688</NlmUniqueID><ISSNLinking>0885-3185</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000368">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D001696">Biomechanical Phenomena</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D005260">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D018476">Hypokinesia</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000175">diagnosis</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008297">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D008875">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009460">Neurologic Examination</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D009949">Orientation</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000175">diagnosis</QualifierName><QualifierName MajorTopicYN="N" UI="Q000503">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011187">Posture</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D011930">Reaction Time</DescriptorName><QualifierName MajorTopicYN="Y" UI="Q000502">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D012016">Reference Values</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N" UI="D016474">Weight-Bearing</DescriptorName><QualifierName MajorTopicYN="N" UI="Q000502">physiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2002</Year><Month>12</Month><Day>5</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>3</Month><Day>26</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2002</Year><Month>12</Month><Day>5</Day><Hour>4</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">12465056</ArticleId><ArticleId IdType="doi">10.1002/mds.10257</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><noCountry><name sortKey="Hui Chan, Christina W Y" sort="Hui Chan, Christina W Y" uniqKey="Hui Chan C" first="Christina W Y" last="Hui-Chan">Christina W Y. Hui-Chan</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Mak, Margaret K Y" sort="Mak, Margaret K Y" uniqKey="Mak M" first="Margaret K Y" last="Mak">Margaret K Y. Mak</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000928 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000928 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:12465056
|texte= Switching of movement direction is central to parkinsonian bradykinesia in sit-to-stand.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:12465056" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |