Neurostimulation of the ventral intermediate thalamic nucleus in inherited myoclonus-dystonia syndrome.
Identifieur interne : 000563 ( Ncbi/Merge ); précédent : 000562; suivant : 000564Neurostimulation of the ventral intermediate thalamic nucleus in inherited myoclonus-dystonia syndrome.
Auteurs : T. Trottenberg [Allemagne] ; W. Meissner ; C. Kabus ; G. Arnold ; T. Funk ; K M Einhaupl ; A. KupschSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2001.
English descriptors
- KwdEn :
- Brain Mapping, Dominance, Cerebral (physiology), Dystonic Disorders (genetics), Dystonic Disorders (physiopathology), Dystonic Disorders (therapy), Electric Stimulation Therapy, Humans, Male, Middle Aged, Myoclonus (genetics), Myoclonus (physiopathology), Myoclonus (therapy), Neurologic Examination, Ventral Thalamic Nuclei (physiopathology).
- MESH :
- genetics : Dystonic Disorders, Myoclonus.
- physiology : Dominance, Cerebral.
- physiopathology : Dystonic Disorders, Myoclonus, Ventral Thalamic Nuclei.
- therapy : Dystonic Disorders, Myoclonus.
- Brain Mapping, Electric Stimulation Therapy, Humans, Male, Middle Aged, Neurologic Examination.
Abstract
We report on the effects of bilateral neurostimulation of the ventral intermediate thalamic nucleus (VIM) in a patient with medically intractable and progressing inherited myoclonus dystonia syndrome (IMDS). Postoperatively, the patient improved by approximately 80% on the modified version of a myoclonus score without any significant change in the dystonic symptoms. This suggests that neurostimulation of the VIM may be an effective treatment for myoclonus in pharmacologically intractable IMDS.
PubMed: 11481711
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pubmed:11481711Le document en format XML
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<author><name sortKey="Trottenberg, T" sort="Trottenberg, T" uniqKey="Trottenberg T" first="T" last="Trottenberg">T. Trottenberg</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Humboldt-University, Charité-Virchow, Berlin, Germany.</nlm:affiliation>
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<wicri:regionArea>Department of Neurology, Humboldt-University, Charité-Virchow, Berlin</wicri:regionArea>
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<author><name sortKey="Kabus, C" sort="Kabus, C" uniqKey="Kabus C" first="C" last="Kabus">C. Kabus</name>
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<author><name sortKey="Arnold, G" sort="Arnold, G" uniqKey="Arnold G" first="G" last="Arnold">G. Arnold</name>
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<author><name sortKey="Funk, T" sort="Funk, T" uniqKey="Funk T" first="T" last="Funk">T. Funk</name>
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<author><name sortKey="Einhaupl, K M" sort="Einhaupl, K M" uniqKey="Einhaupl K" first="K M" last="Einhaupl">K M Einhaupl</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Neurostimulation of the ventral intermediate thalamic nucleus in inherited myoclonus-dystonia syndrome.</title>
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<term>Dominance, Cerebral (physiology)</term>
<term>Dystonic Disorders (genetics)</term>
<term>Dystonic Disorders (physiopathology)</term>
<term>Dystonic Disorders (therapy)</term>
<term>Electric Stimulation Therapy</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Myoclonus (genetics)</term>
<term>Myoclonus (physiopathology)</term>
<term>Myoclonus (therapy)</term>
<term>Neurologic Examination</term>
<term>Ventral Thalamic Nuclei (physiopathology)</term>
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<term>Myoclonus</term>
<term>Ventral Thalamic Nuclei</term>
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<front><div type="abstract" xml:lang="en">We report on the effects of bilateral neurostimulation of the ventral intermediate thalamic nucleus (VIM) in a patient with medically intractable and progressing inherited myoclonus dystonia syndrome (IMDS). Postoperatively, the patient improved by approximately 80% on the modified version of a myoclonus score without any significant change in the dystonic symptoms. This suggests that neurostimulation of the VIM may be an effective treatment for myoclonus in pharmacologically intractable IMDS.</div>
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<Title>Movement disorders : official journal of the Movement Disorder Society</Title>
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<ArticleTitle>Neurostimulation of the ventral intermediate thalamic nucleus in inherited myoclonus-dystonia syndrome.</ArticleTitle>
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<Abstract><AbstractText>We report on the effects of bilateral neurostimulation of the ventral intermediate thalamic nucleus (VIM) in a patient with medically intractable and progressing inherited myoclonus dystonia syndrome (IMDS). Postoperatively, the patient improved by approximately 80% on the modified version of a myoclonus score without any significant change in the dystonic symptoms. This suggests that neurostimulation of the VIM may be an effective treatment for myoclonus in pharmacologically intractable IMDS.</AbstractText>
<CopyrightInformation>Copyright 2001 Movement Disorder Society.</CopyrightInformation>
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