Movement Disorders (revue)

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Consensus statement on the role of acute dopaminergic challenge in Parkinson's disease.

Identifieur interne : 000460 ( Ncbi/Merge ); précédent : 000459; suivant : 000461

Consensus statement on the role of acute dopaminergic challenge in Parkinson's disease.

Auteurs : A. Albanese [Italie] ; U. Bonuccelli ; C. Brefel ; K R Chaudhuri ; C. Colosimo ; T. Eichhorn ; E. Melamed ; P. Pollak ; T. Van Laar ; M. Zappia

Source :

RBID : pubmed:11295770

English descriptors

Abstract

Available evidence on the practice of acute pharmacological challenge tests in parkinsonian patients was reviewed by a committee of experts, which achieved a general consensus. The published data deal mainly with the acute administration of levodopa and apomorphine in Parkinson's disease. Such challenge may serve different purposes, e.g., research, diagnosis, or tailoring of treatment. Unique protocols describing the clinical setting and practice parameters are not available. The present paper describes the scientific background and supplies practical guidelines, whenever possible, to perform and evaluate acute challenge tests in parkinsonian syndromes. With the appropriate indication and setting, acute challenge tests are useful in diagnosis and therapy of Parkinson's disease and related disorders.

PubMed: 11295770

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<div type="abstract" xml:lang="en">Available evidence on the practice of acute pharmacological challenge tests in parkinsonian patients was reviewed by a committee of experts, which achieved a general consensus. The published data deal mainly with the acute administration of levodopa and apomorphine in Parkinson's disease. Such challenge may serve different purposes, e.g., research, diagnosis, or tailoring of treatment. Unique protocols describing the clinical setting and practice parameters are not available. The present paper describes the scientific background and supplies practical guidelines, whenever possible, to perform and evaluate acute challenge tests in parkinsonian syndromes. With the appropriate indication and setting, acute challenge tests are useful in diagnosis and therapy of Parkinson's disease and related disorders.</div>
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