Parkinsonism secondary to bilateral striatal fungal abscesses.
Identifieur interne : 004551 ( Ncbi/Curation ); précédent : 004550; suivant : 004552Parkinsonism secondary to bilateral striatal fungal abscesses.
Auteurs : C H Adler [États-Unis] ; M B Stern ; M L BrooksSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1989.
English descriptors
- KwdEn :
- Adult, Amphotericin B (therapeutic use), Brain Abscess (complications), Brain Abscess (drug therapy), Brain Diseases (complications), Brain Diseases (drug therapy), Corpus Striatum, Humans, Male, Mycoses (complications), Mycoses (drug therapy), Parkinson Disease, Secondary (etiology), Substance Abuse, Intravenous (complications).
- MESH :
- chemical , therapeutic use : Amphotericin B.
- complications : Brain Abscess, Brain Diseases, Mycoses, Substance Abuse, Intravenous.
- drug therapy : Brain Abscess, Brain Diseases, Mycoses.
- etiology : Parkinson Disease, Secondary.
- Adult, Corpus Striatum, Humans, Male.
Abstract
A 24-year-old man with an 11-year history of i.v. drug use rapidly developed parkinsonism clinically indistinguishable from MPTP toxicity and Parkinson's disease. Although tests were negative for the human immunodeficiency virus, radiologic evaluation revealed bilateral striatal lesions. Stereotactic biopsy demonstrated septate hyphae consistent with either aspergillosis or mucormycosis. Gradual improvement followed systemic therapy with amphotericin B.
DOI: 10.1002/mds.870040407
PubMed: 2811892
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