Postural instability, frontotemporal dementia, and ophthalmoplegia: clinicopathological case.
Identifieur interne : 003346 ( Ncbi/Curation ); précédent : 003345; suivant : 003347Postural instability, frontotemporal dementia, and ophthalmoplegia: clinicopathological case.
Auteurs : Francisco Cardoso [Brésil] ; John Hodges ; Andrew H. Evans ; Tamas Revesz ; David R. WilliamsSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2011.
English descriptors
- KwdEn :
- Frontal Lobe (metabolism), Frontotemporal Dementia (complications), Frontotemporal Dementia (pathology), Humans, Male, Middle Aged, Ophthalmoplegia (complications), Ophthalmoplegia (pathology), Posture (physiology), Sensation Disorders (complications), Sensation Disorders (pathology), tau Proteins (metabolism).
- MESH :
- chemical , metabolism : tau Proteins.
- complications : Frontotemporal Dementia, Ophthalmoplegia, Sensation Disorders.
- metabolism : Frontal Lobe.
- pathology : Frontotemporal Dementia, Ophthalmoplegia, Sensation Disorders.
- physiology : Posture.
- Humans, Male, Middle Aged.
Abstract
A 56-year-old man presented with gait disturbance, personality change, and behavioral disturbances. He subsequently developed falls, postural instability, and axial rigidity. The cognitive problems progressed and he developed aphasia and later eye movement abnormalities. He died after 9 years of disease. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered.
DOI: 10.1002/mds.23359
PubMed: 21755535
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pubmed:21755535Le document en format XML
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<affiliation wicri:level="3"><nlm:affiliation>Movement Disorders Unit, Neurology Service, Federal University of Minas Gerais, Belo Horizonte, Brazil.</nlm:affiliation>
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<author><name sortKey="Hodges, John" sort="Hodges, John" uniqKey="Hodges J" first="John" last="Hodges">John Hodges</name>
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<author><name sortKey="Evans, Andrew H" sort="Evans, Andrew H" uniqKey="Evans A" first="Andrew H" last="Evans">Andrew H. Evans</name>
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<author><name sortKey="Revesz, Tamas" sort="Revesz, Tamas" uniqKey="Revesz T" first="Tamas" last="Revesz">Tamas Revesz</name>
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<author><name sortKey="Williams, David R" sort="Williams, David R" uniqKey="Williams D" first="David R" last="Williams">David R. Williams</name>
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<author><name sortKey="Revesz, Tamas" sort="Revesz, Tamas" uniqKey="Revesz T" first="Tamas" last="Revesz">Tamas Revesz</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Ophthalmoplegia (complications)</term>
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<term>Posture (physiology)</term>
<term>Sensation Disorders (complications)</term>
<term>Sensation Disorders (pathology)</term>
<term>tau Proteins (metabolism)</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>tau Proteins</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Frontotemporal Dementia</term>
<term>Ophthalmoplegia</term>
<term>Sensation Disorders</term>
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<term>Ophthalmoplegia</term>
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<front><div type="abstract" xml:lang="en">A 56-year-old man presented with gait disturbance, personality change, and behavioral disturbances. He subsequently developed falls, postural instability, and axial rigidity. The cognitive problems progressed and he developed aphasia and later eye movement abnormalities. He died after 9 years of disease. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered.</div>
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