MovDisordV3, Ncbi, Curation, bibRecord, 002E72

A Recommended Scale for Cognitive Screening in Clinical Trials of Parkinson’s Disease

Identifieur interne : 002E72 ( Ncbi/Curation ); précédent : 002E71; suivant : 002E73

A Recommended Scale for Cognitive Screening in Clinical Trials of Parkinson’s Disease

Auteurs : Kelvin L. Chou [États-Unis] ; Melissa M. Amick [États-Unis] ; Jason Brandt [États-Unis] ; Richard Camicioli [Canada] ; Karen Frei [États-Unis] ; Darren Gitelman [États-Unis] ; Jennifer Goldman [États-Unis] ; John Growdon [États-Unis] ; Howard I. Hurtig [États-Unis] ; Bonnie Levin [États-Unis] ; Irene Litvan [États-Unis] ; Laura Marsh [États-Unis] ; Tanya Simuni [États-Unis] ; Alexander I. Tröster [États-Unis] ; Ergun Y. Uc [États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2010.

RBID : PMC:2978783

English descriptors

KwdEn :
- Clinical Trials as Topic, Cognition, Cognition Disorders (complications), Cognition Disorders (diagnosis), Cognition Disorders (psychology), Humans, Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (psychology), Psychometrics, Questionnaires.
MESH :
- complications : Cognition Disorders, Parkinson Disease.
- diagnosis : Cognition Disorders.
- psychology : Cognition Disorders, Parkinson Disease.
- Clinical Trials as Topic, Cognition, Humans, Neuropsychological Tests, Psychometrics, Questionnaires.

Abstract

Background

Cognitive impairment is common in Parkinson’s disease (PD). There is a critical need for a brief, standard cognitive screening measure for use in PD trials whose primary focus is not on cognition.

Methods

The Parkinson Study Group (PSG) Cognitive/Psychiatric Working Group formed a Task Force to make recommendations for a cognitive scale that could screen for dementia and mild cognitive impairment in clinical trials of PD where cognition is not the primary outcome. This Task Force conducted a systematic literature search for cognitive assessments previously used in a PD population. Scales were then evaluated for their appropriateness to screen for cognitive deficits in clinical trials, including brief administration time (<15 minutes), assessment of the major cognitive domains, and potential to detect subtle cognitive impairment in PD.

Results

Five scales of global cognition met the predetermined screening criteria and were considered for review. Based on the Task Force’s evaluation criteria the Montreal Cognitive Assessment (MoCA), appeared to be the most suitable measure.

Conclusions

This Task Force recommends consideration of the MoCA as a minimum cognitive screening measure in clinical trials of PD where cognitive performance is not the primary outcome measure. The MoCA still requires further study of its diagnostic utility in PD populations but appears to be the most appropriate measure among the currently available brief cognitive assessments. Widespread adoption of a single instrument such as the MoCA in clinical trials can improve comparability between research studies on PD.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978783

DOI: 10.1002/mds.23362
PubMed: 20878991
PubMed Central: 2978783

Links toward previous steps (curation, corpus...)

to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000118
to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :000118
to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000373
to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001545
to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :001545
to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001A70
to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :002E72

Links to Exploration step

PMC:2978783

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Recommended Scale for Cognitive Screening in Clinical Trials of Parkinson’s Disease</title>
<author><name sortKey="Chou, Kelvin L" sort="Chou, Kelvin L" uniqKey="Chou K" first="Kelvin L." last="Chou">Kelvin L. Chou</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Departments of Neurology and Neurosurgery, University of Michigan, Ann Arbor, MI, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Neurology and Neurosurgery, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Amick, Melissa M" sort="Amick, Melissa M" uniqKey="Amick M" first="Melissa M." last="Amick">Melissa M. Amick</name>
<affiliation wicri:level="2"><nlm:aff id="A2">VA Boston Healthcare System and Department of Psychiatry, Boston University School of Medicine, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>VA Boston Healthcare System and Department of Psychiatry, Boston University School of Medicine, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Brandt, Jason" sort="Brandt, Jason" uniqKey="Brandt J" first="Jason" last="Brandt">Jason Brandt</name>
<affiliation wicri:level="2"><nlm:aff id="A3">Departments of Psychiatry and Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Psychiatry and Neurology, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Camicioli, Richard" sort="Camicioli, Richard" uniqKey="Camicioli R" first="Richard" last="Camicioli">Richard Camicioli</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta</wicri:regionArea>
<wicri:noRegion>Alberta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Frei, Karen" sort="Frei, Karen" uniqKey="Frei K" first="Karen" last="Frei">Karen Frei</name>
<affiliation wicri:level="2"><nlm:aff id="A5">The Parkinson's and Movement Disorders Institute, Fountain Valley, CA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Parkinson's and Movement Disorders Institute, Fountain Valley, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gitelman, Darren" sort="Gitelman, Darren" uniqKey="Gitelman D" first="Darren" last="Gitelman">Darren Gitelman</name>
<affiliation wicri:level="2"><nlm:aff id="A6">Departments of Neurology and Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Neurology and Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goldman, Jennifer" sort="Goldman, Jennifer" uniqKey="Goldman J" first="Jennifer" last="Goldman">Jennifer Goldman</name>
<affiliation wicri:level="2"><nlm:aff id="A7">Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Growdon, John" sort="Growdon, John" uniqKey="Growdon J" first="John" last="Growdon">John Growdon</name>
<affiliation wicri:level="2"><nlm:aff id="A8">Department of Neurology, Massachusetts General Hospital, Boston, MA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hurtig, Howard I" sort="Hurtig, Howard I" uniqKey="Hurtig H" first="Howard I." last="Hurtig">Howard I. Hurtig</name>
<affiliation wicri:level="2"><nlm:aff id="A9">Depratment of Neurology, University of Pennsylvania Health System, Philadelphia, PA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Depratment of Neurology, University of Pennsylvania Health System, Philadelphia, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Levin, Bonnie" sort="Levin, Bonnie" uniqKey="Levin B" first="Bonnie" last="Levin">Bonnie Levin</name>
<affiliation wicri:level="2"><nlm:aff id="A10">Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Miami Miller School of Medicine, Miami, FL</wicri:regionArea>
<placeName><region type="state">Floride</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Litvan, Irene" sort="Litvan, Irene" uniqKey="Litvan I" first="Irene" last="Litvan">Irene Litvan</name>
<affiliation wicri:level="2"><nlm:aff id="A11">Department of Neurology, University of Louisville School of Medicine, Louisville, KY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Louisville School of Medicine, Louisville, KY</wicri:regionArea>
<placeName><region type="state">Kentucky</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marsh, Laura" sort="Marsh, Laura" uniqKey="Marsh L" first="Laura" last="Marsh">Laura Marsh</name>
<affiliation wicri:level="2"><nlm:aff id="A12">Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Simuni, Tanya" sort="Simuni, Tanya" uniqKey="Simuni T" first="Tanya" last="Simuni">Tanya Simuni</name>
<affiliation wicri:level="2"><nlm:aff id="A13">Parkinson's Disease and Movement Disorders Center and Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Parkinson's Disease and Movement Disorders Center and Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Troster, Alexander I" sort="Troster, Alexander I" uniqKey="Troster A" first="Alexander I." last="Tröster">Alexander I. Tröster</name>
<affiliation wicri:level="2"><nlm:aff id="A14">Department of Neurology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of North Carolina-Chapel Hill, Chapel Hill, NC</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Uc, Ergun Y" sort="Uc, Ergun Y" uniqKey="Uc E" first="Ergun Y." last="Uc">Ergun Y. Uc</name>
<affiliation wicri:level="4"><nlm:aff id="A15">Department of Neurology, University of Iowa, Iowa City, IA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Iowa, Iowa City, IA</wicri:regionArea>
<placeName><region type="state">Iowa</region>
<settlement type="city">Iowa City</settlement>
</placeName>
<orgName type="university">Université de l'Iowa</orgName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A16">Veterans Affairs Medical Center, Iowa City, IA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Veterans Affairs Medical Center, Iowa City, IA</wicri:regionArea>
<placeName><region type="state">Iowa</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">20878991</idno>
<idno type="pmc">2978783</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978783</idno>
<idno type="RBID">PMC:2978783</idno>
<idno type="doi">10.1002/mds.23362</idno>
<date when="2010">2010</date>
<idno type="wicri:Area/Pmc/Corpus">000118</idno>
<idno type="wicri:Area/Pmc/Curation">000118</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000373</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">001545</idno>
<idno type="wicri:Area/PubMed/Curation">001545</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001A70</idno>
<idno type="wicri:Area/Ncbi/Merge">002E72</idno>
<idno type="wicri:Area/Ncbi/Curation">002E72</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A Recommended Scale for Cognitive Screening in Clinical Trials of Parkinson’s Disease</title>
<author><name sortKey="Chou, Kelvin L" sort="Chou, Kelvin L" uniqKey="Chou K" first="Kelvin L." last="Chou">Kelvin L. Chou</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Departments of Neurology and Neurosurgery, University of Michigan, Ann Arbor, MI, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Neurology and Neurosurgery, University of Michigan, Ann Arbor, MI</wicri:regionArea>
<placeName><region type="state">Michigan</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Amick, Melissa M" sort="Amick, Melissa M" uniqKey="Amick M" first="Melissa M." last="Amick">Melissa M. Amick</name>
<affiliation wicri:level="2"><nlm:aff id="A2">VA Boston Healthcare System and Department of Psychiatry, Boston University School of Medicine, Boston, MA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
<wicri:cityArea>VA Boston Healthcare System and Department of Psychiatry, Boston University School of Medicine, Boston</wicri:cityArea>
</affiliation>
</author>
<author><name sortKey="Brandt, Jason" sort="Brandt, Jason" uniqKey="Brandt J" first="Jason" last="Brandt">Jason Brandt</name>
<affiliation wicri:level="2"><nlm:aff id="A3">Departments of Psychiatry and Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Psychiatry and Neurology, Johns Hopkins University School of Medicine, Baltimore, MD</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Camicioli, Richard" sort="Camicioli, Richard" uniqKey="Camicioli R" first="Richard" last="Camicioli">Richard Camicioli</name>
<affiliation wicri:level="1"><nlm:aff id="A4">Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta</wicri:regionArea>
<wicri:noRegion>Alberta</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Frei, Karen" sort="Frei, Karen" uniqKey="Frei K" first="Karen" last="Frei">Karen Frei</name>
<affiliation wicri:level="2"><nlm:aff id="A5">The Parkinson's and Movement Disorders Institute, Fountain Valley, CA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>The Parkinson's and Movement Disorders Institute, Fountain Valley, CA</wicri:regionArea>
<placeName><region type="state">Californie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gitelman, Darren" sort="Gitelman, Darren" uniqKey="Gitelman D" first="Darren" last="Gitelman">Darren Gitelman</name>
<affiliation wicri:level="2"><nlm:aff id="A6">Departments of Neurology and Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Departments of Neurology and Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Goldman, Jennifer" sort="Goldman, Jennifer" uniqKey="Goldman J" first="Jennifer" last="Goldman">Jennifer Goldman</name>
<affiliation wicri:level="2"><nlm:aff id="A7">Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Growdon, John" sort="Growdon, John" uniqKey="Growdon J" first="John" last="Growdon">John Growdon</name>
<affiliation wicri:level="2"><nlm:aff id="A8">Department of Neurology, Massachusetts General Hospital, Boston, MA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Massachusetts General Hospital, Boston, MA</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hurtig, Howard I" sort="Hurtig, Howard I" uniqKey="Hurtig H" first="Howard I." last="Hurtig">Howard I. Hurtig</name>
<affiliation wicri:level="2"><nlm:aff id="A9">Depratment of Neurology, University of Pennsylvania Health System, Philadelphia, PA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Depratment of Neurology, University of Pennsylvania Health System, Philadelphia, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Levin, Bonnie" sort="Levin, Bonnie" uniqKey="Levin B" first="Bonnie" last="Levin">Bonnie Levin</name>
<affiliation wicri:level="2"><nlm:aff id="A10">Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Miami Miller School of Medicine, Miami, FL</wicri:regionArea>
<placeName><region type="state">Floride</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Litvan, Irene" sort="Litvan, Irene" uniqKey="Litvan I" first="Irene" last="Litvan">Irene Litvan</name>
<affiliation wicri:level="2"><nlm:aff id="A11">Department of Neurology, University of Louisville School of Medicine, Louisville, KY, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Louisville School of Medicine, Louisville, KY</wicri:regionArea>
<placeName><region type="state">Kentucky</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marsh, Laura" sort="Marsh, Laura" uniqKey="Marsh L" first="Laura" last="Marsh">Laura Marsh</name>
<affiliation wicri:level="2"><nlm:aff id="A12">Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX</wicri:regionArea>
<placeName><region type="state">Texas</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Simuni, Tanya" sort="Simuni, Tanya" uniqKey="Simuni T" first="Tanya" last="Simuni">Tanya Simuni</name>
<affiliation wicri:level="2"><nlm:aff id="A13">Parkinson's Disease and Movement Disorders Center and Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Parkinson's Disease and Movement Disorders Center and Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Troster, Alexander I" sort="Troster, Alexander I" uniqKey="Troster A" first="Alexander I." last="Tröster">Alexander I. Tröster</name>
<affiliation wicri:level="2"><nlm:aff id="A14">Department of Neurology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of North Carolina-Chapel Hill, Chapel Hill, NC</wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Uc, Ergun Y" sort="Uc, Ergun Y" uniqKey="Uc E" first="Ergun Y." last="Uc">Ergun Y. Uc</name>
<affiliation wicri:level="4"><nlm:aff id="A15">Department of Neurology, University of Iowa, Iowa City, IA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, University of Iowa, Iowa City, IA</wicri:regionArea>
<placeName><region type="state">Iowa</region>
<settlement type="city">Iowa City</settlement>
</placeName>
<orgName type="university">Université de l'Iowa</orgName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A16">Veterans Affairs Medical Center, Iowa City, IA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Veterans Affairs Medical Center, Iowa City, IA</wicri:regionArea>
<placeName><region type="state">Iowa</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2010">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Clinical Trials as Topic</term>
<term>Cognition</term>
<term>Cognition Disorders (complications)</term>
<term>Cognition Disorders (diagnosis)</term>
<term>Cognition Disorders (psychology)</term>
<term>Humans</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (psychology)</term>
<term>Psychometrics</term>
<term>Questionnaires</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Cognition Disorders</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Cognition Disorders</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Clinical Trials as Topic</term>
<term>Cognition</term>
<term>Humans</term>
<term>Neuropsychological Tests</term>
<term>Psychometrics</term>
<term>Questionnaires</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">Cognitive impairment is common in Parkinson’s disease (PD). There is a critical need for a brief, standard cognitive screening measure for use in PD trials whose primary focus is not on cognition.</p>
</sec>
<sec sec-type="methods" id="S2"><title>Methods</title>
<p id="P2">The Parkinson Study Group (PSG) Cognitive/Psychiatric Working Group formed a Task Force to make recommendations for a cognitive scale that could screen for dementia and mild cognitive impairment in clinical trials of PD where cognition is not the primary outcome. This Task Force conducted a systematic literature search for cognitive assessments previously used in a PD population. Scales were then evaluated for their appropriateness to screen for cognitive deficits in clinical trials, including brief administration time (<15 minutes), assessment of the major cognitive domains, and potential to detect subtle cognitive impairment in PD.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Five scales of global cognition met the predetermined screening criteria and were considered for review. Based on the Task Force’s evaluation criteria the Montreal Cognitive Assessment (MoCA), appeared to be the most suitable measure.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">This Task Force recommends consideration of the MoCA as a minimum cognitive screening measure in clinical trials of PD where cognitive performance is not the primary outcome measure. The MoCA still requires further study of its diagnostic utility in PD populations but appears to be the most appropriate measure among the currently available brief cognitive assessments. Widespread adoption of a single instrument such as the MoCA in clinical trials can improve comparability between research studies on PD.</p>
</sec>
</div>
</front>
</TEI>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002E72 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 002E72 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    Ncbi
   |étape=   Curation
   |type=    RBID
   |clé=     PMC:2978783
   |texte=   A Recommended Scale for Cognitive Screening in Clinical Trials of Parkinson’s Disease
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i   -Sk "pubmed:20878991" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a MovDisordV3

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

A Recommended Scale for Cognitive Screening in Clinical Trials of Parkinson’s Disease

A Recommended Scale for Cognitive Screening in Clinical Trials of Parkinson’s Disease

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki