Executive functioning in adult patients with Sydenham's chorea.
Identifieur interne : 002B66 ( Ncbi/Curation ); précédent : 002B65; suivant : 002B67Executive functioning in adult patients with Sydenham's chorea.
Auteurs : Rogério Beato [Brésil] ; Débora P. Maia ; Antônio Lúcio Teixeira ; Francisco CardosoSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.
English descriptors
- KwdEn :
- Adolescent, Adult, Age of Onset, Anti-Bacterial Agents (therapeutic use), Anti-Dyskinesia Agents (therapeutic use), Anticonvulsants (therapeutic use), Chorea (drug therapy), Chorea (epidemiology), Chorea (physiopathology), Cognition Disorders (diagnosis), Cognition Disorders (epidemiology), Executive Function, Female, Humans, Male, Neuropsychological Tests, Penicillin G Benzathine (therapeutic use), Pimozide (therapeutic use), Severity of Illness Index, Valproic Acid (therapeutic use), Young Adult.
- MESH :
- chemical , therapeutic use : Anti-Bacterial Agents, Anti-Dyskinesia Agents, Anticonvulsants, Penicillin G Benzathine, Pimozide, Valproic Acid.
- diagnosis : Cognition Disorders.
- drug therapy : Chorea.
- epidemiology : Chorea, Cognition Disorders.
- physiopathology : Chorea.
- Adolescent, Adult, Age of Onset, Executive Function, Female, Humans, Male, Neuropsychological Tests, Severity of Illness Index, Young Adult.
Abstract
Sydenham's chorea (SC) is characterized by a combination of motor and behavioral findings. Cognitive function has been scarcely studied in this condition. The aim of this study is to investigate executive functions in adult patients with SC. We performed neuropsychological tests to evaluate executive functions in controls and adult patients with persistent and in remission SC. Patients with SC have impairment in Tower of London task, reduced verbal fluency, and lower scores in the Stroop test. A subset of adult patients with SC present with executive dysfunction, even when chorea is in remission.
DOI: 10.1002/mds.23154
PubMed: 20461802
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pubmed:20461802Le document en format XML
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<author><name sortKey="Beato, Rogerio" sort="Beato, Rogerio" uniqKey="Beato R" first="Rogério" last="Beato">Rogério Beato</name>
<affiliation wicri:level="2"><nlm:affiliation>Neurology Service, Internal Medicine Department, The Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
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<placeName><region type="state">Minas Gerais</region>
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<author><name sortKey="Maia, Debora P" sort="Maia, Debora P" uniqKey="Maia D" first="Débora P" last="Maia">Débora P. Maia</name>
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<author><name sortKey="Teixeira, Antonio Lucio" sort="Teixeira, Antonio Lucio" uniqKey="Teixeira A" first="Antônio Lúcio" last="Teixeira">Antônio Lúcio Teixeira</name>
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<author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Executive functioning in adult patients with Sydenham's chorea.</title>
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<affiliation wicri:level="2"><nlm:affiliation>Neurology Service, Internal Medicine Department, The Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
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<author><name sortKey="Maia, Debora P" sort="Maia, Debora P" uniqKey="Maia D" first="Débora P" last="Maia">Débora P. Maia</name>
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<author><name sortKey="Teixeira, Antonio Lucio" sort="Teixeira, Antonio Lucio" uniqKey="Teixeira A" first="Antônio Lúcio" last="Teixeira">Antônio Lúcio Teixeira</name>
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<author><name sortKey="Cardoso, Francisco" sort="Cardoso, Francisco" uniqKey="Cardoso F" first="Francisco" last="Cardoso">Francisco Cardoso</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2010" type="published">2010</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age of Onset</term>
<term>Anti-Bacterial Agents (therapeutic use)</term>
<term>Anti-Dyskinesia Agents (therapeutic use)</term>
<term>Anticonvulsants (therapeutic use)</term>
<term>Chorea (drug therapy)</term>
<term>Chorea (epidemiology)</term>
<term>Chorea (physiopathology)</term>
<term>Cognition Disorders (diagnosis)</term>
<term>Cognition Disorders (epidemiology)</term>
<term>Executive Function</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Neuropsychological Tests</term>
<term>Penicillin G Benzathine (therapeutic use)</term>
<term>Pimozide (therapeutic use)</term>
<term>Severity of Illness Index</term>
<term>Valproic Acid (therapeutic use)</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Bacterial Agents</term>
<term>Anti-Dyskinesia Agents</term>
<term>Anticonvulsants</term>
<term>Penicillin G Benzathine</term>
<term>Pimozide</term>
<term>Valproic Acid</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Chorea</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Chorea</term>
<term>Cognition Disorders</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Chorea</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age of Onset</term>
<term>Executive Function</term>
<term>Female</term>
<term>Humans</term>
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<term>Neuropsychological Tests</term>
<term>Severity of Illness Index</term>
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<front><div type="abstract" xml:lang="en">Sydenham's chorea (SC) is characterized by a combination of motor and behavioral findings. Cognitive function has been scarcely studied in this condition. The aim of this study is to investigate executive functions in adult patients with SC. We performed neuropsychological tests to evaluate executive functions in controls and adult patients with persistent and in remission SC. Patients with SC have impairment in Tower of London task, reduced verbal fluency, and lower scores in the Stroop test. A subset of adult patients with SC present with executive dysfunction, even when chorea is in remission.</div>
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