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Substantia nigra echogenicity in progressive supranuclear palsy.

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Substantia nigra echogenicity in progressive supranuclear palsy.

Auteurs : Jens Ebentheuer [Allemagne] ; Monica Canelo ; Ellen Trautmann ; Claudia Trenkwalder

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.

RBID : pubmed:20198715

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Female, Humans, Male, Substantia Nigra (ultrasonography), Supranuclear Palsy, Progressive (pathology), Supranuclear Palsy, Progressive (ultrasonography), Ultrasonography, Doppler, Transcranial (methods).
MESH :
- methods : Ultrasonography, Doppler, Transcranial.
- pathology : Supranuclear Palsy, Progressive.
- ultrasonography : Substantia Nigra, Supranuclear Palsy, Progressive.
- Aged, Aged, 80 and over, Female, Humans, Male.

Abstract

A normoechogenic substantia nigra (SN) is a typical finding in transcranial sonography in patients with progressive supranuclear palsy (PSP), whereas in patients with Parkinson's disease a hyperechogenic SN is characteristic. A recent classification scheme recommends the differentiation of PSP patients into those with Richardson's syndrome (RS) and those with PSP-Parkinsonism (PSP-P). We investigated 34 PSP patients (27 RS, 7 PSP-P) with ultrasound of the substantia nigra in search of differentiations in the two groups. We found that most of the PSP-P patients, according to recently published criteria, had a hyperechogenic SN (6 of 7): right (cm(2)) median 0.22, 25% percentile 0.21 and 75% percentile 0.36 (cm(2)); left (cm(2)) median 0.21, 25% percentile 0.20 and 75% percentile 0.30 and a normal third ventricle (mean mm) +/-SD: 7.1 +/- 2.43). In RS patients a normoechogenic SN (26 of 27) and an enlarged third ventricle (mean mm) +/-SD: 10.3 +/- 2.41) was found. These differences may elucidate the pathological differences of RS and PSP-P.

DOI: 10.1002/mds.22981
PubMed: 20198715

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<author><name sortKey="Ebentheuer, Jens" sort="Ebentheuer, Jens" uniqKey="Ebentheuer J" first="Jens" last="Ebentheuer">Jens Ebentheuer</name>
<affiliation wicri:level="3"><nlm:affiliation>Paracelsus-Elena-Klinik, Center of Parkinsonism and Movement Disorders, Kassel, Germany. j.ebentheuer@gmx.de</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Paracelsus-Elena-Klinik, Center of Parkinsonism and Movement Disorders, Kassel</wicri:regionArea>
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<author><name sortKey="Trenkwalder, Claudia" sort="Trenkwalder, Claudia" uniqKey="Trenkwalder C" first="Claudia" last="Trenkwalder">Claudia Trenkwalder</name>
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<term>Substantia Nigra (ultrasonography)</term>
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<term>Supranuclear Palsy, Progressive (ultrasonography)</term>
<term>Ultrasonography, Doppler, Transcranial (methods)</term>
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<term>Supranuclear Palsy, Progressive</term>
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<front><div type="abstract" xml:lang="en">A normoechogenic substantia nigra (SN) is a typical finding in transcranial sonography in patients with progressive supranuclear palsy (PSP), whereas in patients with Parkinson's disease a hyperechogenic SN is characteristic. A recent classification scheme recommends the differentiation of PSP patients into those with Richardson's syndrome (RS) and those with PSP-Parkinsonism (PSP-P). We investigated 34 PSP patients (27 RS, 7 PSP-P) with ultrasound of the substantia nigra in search of differentiations in the two groups. We found that most of the PSP-P patients, according to recently published criteria, had a hyperechogenic SN (6 of 7): right (cm(2)) median 0.22, 25% percentile 0.21 and 75% percentile 0.36 (cm(2)); left (cm(2)) median 0.21, 25% percentile 0.20 and 75% percentile 0.30 and a normal third ventricle (mean mm) +/-SD: 7.1 +/- 2.43). In RS patients a normoechogenic SN (26 of 27) and an enlarged third ventricle (mean mm) +/-SD: 10.3 +/- 2.41) was found. These differences may elucidate the pathological differences of RS and PSP-P.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Substantia nigra echogenicity in progressive supranuclear palsy.

Substantia nigra echogenicity in progressive supranuclear palsy.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki