Effect of cervical dystonia on employment: A retrospective analysis of the ability of treatment to restore premorbid employment status.
Identifieur interne : 002677 ( Ncbi/Curation ); précédent : 002676; suivant : 002678Effect of cervical dystonia on employment: A retrospective analysis of the ability of treatment to restore premorbid employment status.
Auteurs : Eric S. Molho [États-Unis] ; Nitendra Agarwal ; Katy Regan ; Donald S. Higgins ; Stewart A. FactorSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2009.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Anti-Dyskinesia Agents, Botulinum Toxins.
- drug therapy : Torticollis.
- economics : Torticollis.
- epidemiology : Torticollis.
- Disability Evaluation, Employment, Female, Humans, Male, Middle Aged, Pain Measurement, Retrospective Studies.
Abstract
Using a structured interview method, we sought to address the following questions regarding cervical dystonia (CD) and employment: (1) what is the frequency and severity of job impairment in CD; (2) what are the clinical features that contribute to job impairment; (3) how does the effectiveness of botulinum toxin (BTx) compare to oral medications in restoring employment status. In our population of 155 CD patients, employment was affected by CD in 53.3% (31.2% reduced hours or responsibilities, 3.3% changed to different job, 18.9% loss of employment) and 68.9% of patients reported reduced overall productivity. The likelihood of altered employment (P < 0.0006), reduced productivity (P < 0.0001), and seeking disability benefits (P < 0.003) was significantly associated with the presence of neck pain, but not type of employment, spasmodic head motions, or duration of CD symptoms before treatment with BTx. Treatment with BTx was more likely to improve employment status than oral medications (66.1 vs. 18.5%) and much more likely to restore full employment with normal productivity (12.9 vs. 0.0%). These findings suggest that employment status is frequently affected by CD, particularly in patients withneck pain. BTx is significantly more effective than oral medications in restoring premorbid employment status.
DOI: 10.1002/mds.22622
PubMed: 19441129
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pubmed:19441129Le document en format XML
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Molho</name><affiliation wicri:level="2"><nlm:affiliation>Neurosciences Institute, Albany Medical Center, NY 12208, USA. molhoe@mail.amc.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Neurosciences Institute, Albany Medical Center, NY 12208</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Agarwal, Nitendra" sort="Agarwal, Nitendra" uniqKey="Agarwal N" first="Nitendra" last="Agarwal">Nitendra Agarwal</name></author><author><name sortKey="Regan, Katy" sort="Regan, Katy" uniqKey="Regan K" first="Katy" last="Regan">Katy Regan</name></author><author><name sortKey="Higgins, Donald S" sort="Higgins, Donald S" uniqKey="Higgins D" first="Donald S" last="Higgins">Donald S. Higgins</name></author><author><name sortKey="Factor, Stewart A" sort="Factor, Stewart A" uniqKey="Factor S" first="Stewart A" last="Factor">Stewart A. 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Molho</name><affiliation wicri:level="2"><nlm:affiliation>Neurosciences Institute, Albany Medical Center, NY 12208, USA. molhoe@mail.amc.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Neurosciences Institute, Albany Medical Center, NY 12208</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Agarwal, Nitendra" sort="Agarwal, Nitendra" uniqKey="Agarwal N" first="Nitendra" last="Agarwal">Nitendra Agarwal</name></author><author><name sortKey="Regan, Katy" sort="Regan, Katy" uniqKey="Regan K" first="Katy" last="Regan">Katy Regan</name></author><author><name sortKey="Higgins, Donald S" sort="Higgins, Donald S" uniqKey="Higgins D" first="Donald S" last="Higgins">Donald S. Higgins</name></author><author><name sortKey="Factor, Stewart A" sort="Factor, Stewart A" uniqKey="Factor S" first="Stewart A" last="Factor">Stewart A. Factor</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Dyskinesia Agents (therapeutic use)</term><term>Botulinum Toxins (therapeutic use)</term><term>Disability Evaluation</term><term>Employment</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pain Measurement</term><term>Retrospective Studies</term><term>Torticollis (drug therapy)</term><term>Torticollis (economics)</term><term>Torticollis (epidemiology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Dyskinesia Agents</term><term>Botulinum Toxins</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Torticollis</term></keywords><keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>Torticollis</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Torticollis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Disability Evaluation</term><term>Employment</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pain Measurement</term><term>Retrospective Studies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Using a structured interview method, we sought to address the following questions regarding cervical dystonia (CD) and employment: (1) what is the frequency and severity of job impairment in CD; (2) what are the clinical features that contribute to job impairment; (3) how does the effectiveness of botulinum toxin (BTx) compare to oral medications in restoring employment status. In our population of 155 CD patients, employment was affected by CD in 53.3% (31.2% reduced hours or responsibilities, 3.3% changed to different job, 18.9% loss of employment) and 68.9% of patients reported reduced overall productivity. The likelihood of altered employment (P < 0.0006), reduced productivity (P < 0.0001), and seeking disability benefits (P < 0.003) was significantly associated with the presence of neck pain, but not type of employment, spasmodic head motions, or duration of CD symptoms before treatment with BTx. Treatment with BTx was more likely to improve employment status than oral medications (66.1 vs. 18.5%) and much more likely to restore full employment with normal productivity (12.9 vs. 0.0%). These findings suggest that employment status is frequently affected by CD, particularly in patients withneck pain. BTx is significantly more effective than oral medications in restoring premorbid employment status.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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