MovDisordV3, Ncbi, Curation, bibRecord, 002496

Traditional Chinese medicine on four patients with Huntington's disease.

Identifieur interne : 002496 ( Ncbi/Curation ); précédent : 002495; suivant : 002497

Traditional Chinese medicine on four patients with Huntington's disease.

Auteurs : Takashi Satoh [Japon] ; Toshiyuki Takahashi ; Koh Iwasaki ; Hideaki Tago ; Takashi Seki ; Nobuo Yaegashi ; Muneshige Tobita ; Hiroyuki Arai

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2009.

RBID : pubmed:19133663

English descriptors

KwdEn :
- Aged, Cross-Over Studies, Drugs, Chinese Herbal (therapeutic use), Female, Humans, Huntington Disease (genetics), Medicine, Chinese Traditional (methods), Middle Aged, Pilot Projects.
MESH :
- chemical , therapeutic use : Drugs, Chinese Herbal.
- genetics : Huntington Disease.
- methods : Medicine, Chinese Traditional.
- Aged, Cross-Over Studies, Female, Humans, Middle Aged, Pilot Projects.

Abstract

Four Huntington's disease (HD) patients were treated with traditional Chinese medicines Yi-Gan San (YGS) and Chaihu-Jia-Longgu-Muli Tan (CLMT) in a cross-over manner. Two patients took YGS for 8 weeks first, and after 4 weeks of washing out, they took CLMT for 8 weeks. Two other patients took these medicines in reverse order. All patients showed a decrease in the Unified Huntington's Disease Rating Scale-motor assessment (from 106.3 +/- 4.7 to 89.6 +/- 5.8 as mean +/- SD, P = 0.0004) by YGS treatment with no extrapiramidal symptoms or changes of cognition or ADL. Our study suggests a possibility of a new treatment for involuntary movements.

DOI: 10.1002/mds.22447
PubMed: 19133663

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Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Traditional Chinese medicine on four patients with Huntington's disease.</title>
<author><name sortKey="Satoh, Takashi" sort="Satoh, Takashi" uniqKey="Satoh T" first="Takashi" last="Satoh">Takashi Satoh</name>
<affiliation wicri:level="1"><nlm:affiliation>National Yonezawa Hospital, Yonezawa City, Yamagata, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Yonezawa Hospital, Yonezawa City, Yamagata</wicri:regionArea>
<wicri:noRegion>Yamagata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Takahashi, Toshiyuki" sort="Takahashi, Toshiyuki" uniqKey="Takahashi T" first="Toshiyuki" last="Takahashi">Toshiyuki Takahashi</name>
</author>
<author><name sortKey="Iwasaki, Koh" sort="Iwasaki, Koh" uniqKey="Iwasaki K" first="Koh" last="Iwasaki">Koh Iwasaki</name>
</author>
<author><name sortKey="Tago, Hideaki" sort="Tago, Hideaki" uniqKey="Tago H" first="Hideaki" last="Tago">Hideaki Tago</name>
</author>
<author><name sortKey="Seki, Takashi" sort="Seki, Takashi" uniqKey="Seki T" first="Takashi" last="Seki">Takashi Seki</name>
</author>
<author><name sortKey="Yaegashi, Nobuo" sort="Yaegashi, Nobuo" uniqKey="Yaegashi N" first="Nobuo" last="Yaegashi">Nobuo Yaegashi</name>
</author>
<author><name sortKey="Tobita, Muneshige" sort="Tobita, Muneshige" uniqKey="Tobita M" first="Muneshige" last="Tobita">Muneshige Tobita</name>
</author>
<author><name sortKey="Arai, Hiroyuki" sort="Arai, Hiroyuki" uniqKey="Arai H" first="Hiroyuki" last="Arai">Hiroyuki Arai</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2009">2009</date>
<idno type="doi">10.1002/mds.22447</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Traditional Chinese medicine on four patients with Huntington's disease.</title>
<author><name sortKey="Satoh, Takashi" sort="Satoh, Takashi" uniqKey="Satoh T" first="Takashi" last="Satoh">Takashi Satoh</name>
<affiliation wicri:level="1"><nlm:affiliation>National Yonezawa Hospital, Yonezawa City, Yamagata, Japan.</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>National Yonezawa Hospital, Yonezawa City, Yamagata</wicri:regionArea>
<wicri:noRegion>Yamagata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Takahashi, Toshiyuki" sort="Takahashi, Toshiyuki" uniqKey="Takahashi T" first="Toshiyuki" last="Takahashi">Toshiyuki Takahashi</name>
</author>
<author><name sortKey="Iwasaki, Koh" sort="Iwasaki, Koh" uniqKey="Iwasaki K" first="Koh" last="Iwasaki">Koh Iwasaki</name>
</author>
<author><name sortKey="Tago, Hideaki" sort="Tago, Hideaki" uniqKey="Tago H" first="Hideaki" last="Tago">Hideaki Tago</name>
</author>
<author><name sortKey="Seki, Takashi" sort="Seki, Takashi" uniqKey="Seki T" first="Takashi" last="Seki">Takashi Seki</name>
</author>
<author><name sortKey="Yaegashi, Nobuo" sort="Yaegashi, Nobuo" uniqKey="Yaegashi N" first="Nobuo" last="Yaegashi">Nobuo Yaegashi</name>
</author>
<author><name sortKey="Tobita, Muneshige" sort="Tobita, Muneshige" uniqKey="Tobita M" first="Muneshige" last="Tobita">Muneshige Tobita</name>
</author>
<author><name sortKey="Arai, Hiroyuki" sort="Arai, Hiroyuki" uniqKey="Arai H" first="Hiroyuki" last="Arai">Hiroyuki Arai</name>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2009" type="published">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Cross-Over Studies</term>
<term>Drugs, Chinese Herbal (therapeutic use)</term>
<term>Female</term>
<term>Humans</term>
<term>Huntington Disease (genetics)</term>
<term>Medicine, Chinese Traditional (methods)</term>
<term>Middle Aged</term>
<term>Pilot Projects</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Drugs, Chinese Herbal</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Huntington Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Medicine, Chinese Traditional</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Cross-Over Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Pilot Projects</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Four Huntington's disease (HD) patients were treated with traditional Chinese medicines Yi-Gan San (YGS) and Chaihu-Jia-Longgu-Muli Tan (CLMT) in a cross-over manner. Two patients took YGS for 8 weeks first, and after 4 weeks of washing out, they took CLMT for 8 weeks. Two other patients took these medicines in reverse order. All patients showed a decrease in the Unified Huntington's Disease Rating Scale-motor assessment (from 106.3 +/- 4.7 to 89.6 +/- 5.8 as mean +/- SD, P = 0.0004) by YGS treatment with no extrapiramidal symptoms or changes of cognition or ADL. Our study suggests a possibility of a new treatment for involuntary movements.</div>
</front>
</TEI>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Traditional Chinese medicine on four patients with Huntington's disease.

Traditional Chinese medicine on four patients with Huntington's disease.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki