Validation of the freezing of gait questionnaire in patients with Parkinson's disease.
Identifieur interne : 002486 ( Ncbi/Curation ); précédent : 002485; suivant : 002487Validation of the freezing of gait questionnaire in patients with Parkinson's disease.
Auteurs : Nir Giladi [Israël] ; Joseph Tal ; Tali Azulay ; Oliver Rascol ; David J. Brooks ; Eldad Melamed ; Wolfgang Oertel ; Werner Poewe [Autriche] ; Fabrizio Stocchi ; Eduardo TolosaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2009.
English descriptors
- KwdEn :
- Aged, Analysis of Variance, Antiparkinson Agents (adverse effects), Antiparkinson Agents (therapeutic use), Catechols (therapeutic use), Double-Blind Method, Female, Freezing Reaction, Cataleptic (drug effects), Freezing Reaction, Cataleptic (physiology), Gait Disorders, Neurologic (chemically induced), Gait Disorders, Neurologic (diagnosis), Gait Disorders, Neurologic (drug therapy), Gait Disorders, Neurologic (physiopathology), Humans, Indans (therapeutic use), Levodopa (adverse effects), Male, Middle Aged, Neuroprotective Agents (therapeutic use), Nitriles (therapeutic use), Parkinson Disease (drug therapy), Principal Component Analysis, Psychiatric Status Rating Scales, Questionnaires, Reproducibility of Results, Severity of Illness Index, Statistics as Topic.
- MESH :
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- chemical , therapeutic use : Antiparkinson Agents, Catechols, Indans, Neuroprotective Agents, Nitriles.
- chemically induced : Gait Disorders, Neurologic.
- diagnosis : Gait Disorders, Neurologic.
- drug effects : Freezing Reaction, Cataleptic.
- drug therapy : Gait Disorders, Neurologic, Parkinson Disease.
- physiology : Freezing Reaction, Cataleptic.
- physiopathology : Gait Disorders, Neurologic.
- Aged, Analysis of Variance, Double-Blind Method, Female, Humans, Male, Middle Aged, Principal Component Analysis, Psychiatric Status Rating Scales, Questionnaires, Reproducibility of Results, Severity of Illness Index, Statistics as Topic.
Abstract
To revalidate the Freezing of Gait Questionnaire (FOG-Q), patients with Parkinson's disease (PD) were randomly assigned to receive rasagiline (1 mg/day) (n = 150), entacapone (200 mg with each dose of levodopa) (n = 150), or placebo (n = 154). Patients were assessed at baseline and after 10 weeks using the FOG-Q, Unified Parkinson's Disease Rating Scale (UPDRS), Beck Depression Inventory (BDI), and Parkinson's Disease Questionnaire (PDQ-39). FOG-Q dimensionality, test-retest reliability, and internal reliability were examined. Convergent and divergent validities were assessed by correlating FOG-Q with UPDRS, BDI, and PDQ-39. Comparisons between FOG-Q item 3 and UPDRS item 14 were also made. Principal component analysis indicated that FOG-Q measures a single dimension. Test-retest reliability and internal reliability of FOG-Q score was high. FOG-Q was best correlated to items of the UPDRS relating to walking, general motor issues, and mobility. Correlations between baseline and endpoint suggested that FOG-Q item 3 is at least as reliable as UPDRS item 14. At baseline, 85.9% of patients were identified as "Freezers" using FOG-Q item 3 (> or =1) and 44.1% using UPDRS item 14 (> or =1) (P < 0.001). FOG-Q was a reliable tool for the assessment of treatment intervention. FOG-Q item 3 was effective as a screening question for the presence of FOG.
DOI: 10.1002/mds.21745
PubMed: 19127595
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Brooks</name></author><author><name sortKey="Melamed, Eldad" sort="Melamed, Eldad" uniqKey="Melamed E" first="Eldad" last="Melamed">Eldad Melamed</name></author><author><name sortKey="Oertel, Wolfgang" sort="Oertel, Wolfgang" uniqKey="Oertel W" first="Wolfgang" last="Oertel">Wolfgang Oertel</name></author><author><name sortKey="Poewe, Werner H" sort="Poewe, Werner H" uniqKey="Poewe W" first="Werner H" last="Poewe">Werner Poewe</name><affiliation><country>Autriche</country><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName></affiliation></author><author><name sortKey="Stocchi, Fabrizio" sort="Stocchi, Fabrizio" uniqKey="Stocchi F" first="Fabrizio" last="Stocchi">Fabrizio Stocchi</name></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="doi">10.1002/mds.21745</idno><idno type="RBID">pubmed:19127595</idno><idno type="pmid">19127595</idno><idno type="wicri:Area/PubMed/Corpus">001E78</idno><idno type="wicri:Area/PubMed/Curation">001E78</idno><idno type="wicri:Area/PubMed/Checkpoint">001B07</idno><idno type="wicri:Area/Ncbi/Merge">002486</idno><idno type="wicri:Area/Ncbi/Curation">002486</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Validation of the freezing of gait questionnaire in patients with Parkinson's disease.</title><author><name sortKey="Giladi, Nir" sort="Giladi, Nir" uniqKey="Giladi N" first="Nir" last="Giladi">Nir Giladi</name><affiliation wicri:level="1"><nlm:affiliation>Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. nirg@tasmc.health.gov.il</nlm:affiliation><country xml:lang="fr">Israël</country><wicri:regionArea>Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv</wicri:regionArea><wicri:noRegion>Tel-Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Tal, Joseph" sort="Tal, Joseph" uniqKey="Tal J" first="Joseph" last="Tal">Joseph Tal</name></author><author><name sortKey="Azulay, Tali" sort="Azulay, Tali" uniqKey="Azulay T" first="Tali" last="Azulay">Tali Azulay</name></author><author><name sortKey="Rascol, Oliver" sort="Rascol, Oliver" uniqKey="Rascol O" first="Oliver" last="Rascol">Oliver Rascol</name></author><author><name sortKey="Brooks, David J" sort="Brooks, David J" uniqKey="Brooks D" first="David J" last="Brooks">David J. 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Patients were assessed at baseline and after 10 weeks using the FOG-Q, Unified Parkinson's Disease Rating Scale (UPDRS), Beck Depression Inventory (BDI), and Parkinson's Disease Questionnaire (PDQ-39). FOG-Q dimensionality, test-retest reliability, and internal reliability were examined. Convergent and divergent validities were assessed by correlating FOG-Q with UPDRS, BDI, and PDQ-39. Comparisons between FOG-Q item 3 and UPDRS item 14 were also made. Principal component analysis indicated that FOG-Q measures a single dimension. Test-retest reliability and internal reliability of FOG-Q score was high. FOG-Q was best correlated to items of the UPDRS relating to walking, general motor issues, and mobility. Correlations between baseline and endpoint suggested that FOG-Q item 3 is at least as reliable as UPDRS item 14. At baseline, 85.9% of patients were identified as "Freezers" using FOG-Q item 3 (> or =1) and 44.1% using UPDRS item 14 (> or =1) (P < 0.001). FOG-Q was a reliable tool for the assessment of treatment intervention. FOG-Q item 3 was effective as a screening question for the presence of FOG.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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